MCCQE Part I
Study Guide
Table of Contents
Welcome to AMBOSS!
Scoring System
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Learning content
S01: CARDIOVASCULAR MEDICINE
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S02: RESPIRATORY MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8.
S03: ENDOCRINOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
S04: GASTROENTEROLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
S05: RENAL MEDICINE .
S06: HEMATOLOGY
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S07: INFECTIOUS DISEASES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21
S08: NEUROLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
S09: ONCOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
S10:. DERMATOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
S11: HEAD AND NECK / EYE / EAR NOSE AND THROAT . . . . . . . . . . . . . . . . . . . 30
S12: MUSCULOSKELETAL / ORTHOPAEDICS / RHEUMATOLOGY . . . . . . . . . . . . . . . 33
S13: OBSTETRICS & GYNAECOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
S14: PSYCHIATRY . . . . . . . . . . . . . . . . . . . . . . . . . .
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S15: PEDIATRIC MEDICINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
S16: NUTRITION / METABOLISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
S17: CLINICAL PHARMACOLOGY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
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S18: CLINICAL IMMUNOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
S19: CRITICAL CARE / ANAESTHESIA / EMERGENCY MEDICINE . . . . . . . . . . . . . . . . 51
S20: PUBLIC HEALTH / LAW / ETHICS . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
> Table of Content | 2
Welcome to AMBOSS!
Created by a team of dedicated physicians, AMBOSS is an interactive library of 20,000+ medical topics interlinked with a Question Bank with over 5,000 clinical case-based questions. With all the necessary resources
in one place, AMBOSS delivers up-to-date medical knowledge to students, physicians, and faculty around the
world.
In this MCCQE Part I Study Guide, we’ve provided you with a comprehensive checklist of the Medical Expert
Objectives linked to the corresponding AMBOSS articles.
To use this resource for your studies, click on each topic and you will be directed to the assigned articles from
the AMBOSS library. From the articles, you will also be able to access the corresponding questions in the
AMBOSS Qbank.
Click here to open
library articles
Click here to answer
multiple choice questions
We recommend that all candidates read the official MCC “Objectives for the Qualifying Examination” guidelines
before commencing your studies. Links to important Canadian guidelines and clinical resources are also
included in this Study Guide.
With AMBOSS, you’ll be able to study for your exams online, but you can also access our study resources
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> Table of Content | 3
MCCQE Part I
Additional tips and resources
The Medical Council of Canada Qualifying Examination (MCCQE) Part I is the standardized, cumulative test for
all medical students wishing to practice medicine in Canada. It is based on the MCC Objectives and covers the
foundational medical knowledge and critical thinking expected of a physician in Canada.
Additional tips and resources are listed below:
General MCCQE Information
https://www.mcc.ca/examinations/mccqe-part-i/
MCCQE Part I Scoring System
https://www.mcc.ca/examinations/mccqe-part-i/scoring/
List of Suggested Reference Materials
https://www.mcc.ca/examinations/list-of-suggested-reference-materials/
Clinical Guidelines- Joule (Canadian Medical Association)
https://joulecma.ca/cpg/homepage
Canadian Task Force on Preventive Health Care
https://canadiantaskforce.ca/
> Table of Content | 4
S01: Cardiovascular Medicine
Theme
Topic
Cardiorespiratory arrest
Cardiopulmonary resuscitation (CPR)
Cardiovascular examination
Cardiovascular examination
Approach to the patient with chest pain
ECG
Chest pain
Approach to the patient with edema
Edema
Overview of cardiac arrhythmias (Cardiac arrhythmias)
Atrial fibrillation
Arrhythmias
Paroxysmal supraventricular tachycardia
Ventricular tachycardia
Ventricular fibrillation
Syncope
Supraventricular premature beats
Sick sinus syndrome
Dysrhythmias
Ventricular premature beats
Atrioventricular block
Long QT syndrome
Acute and chronic heart failure
Congestive heart failure
Principles of coronary artery disease
Atherosclerosis
Ischemic heart disease and acute coronary syndromes
Acute coronary syndrome
Cardiac catheterization
Coronary artery bypass grafting
Hypertension
Hypertension and hypertensive vascular disease
Renal artery stenosis
> Table of Content | 5
S01: Cardiovascular Medicine
Theme
Topic
Valvular heart diseases
Aortic valve stenosis
Aortic regurgitation
Mitral stenosis
Valvular Heart Diseases
Mitral regurgitation
Mitral valve prolapse
Infective endocarditis
Rheumatic fever
Pericarditis
Pericardial disease and myocarditis
Myocarditis
Pericardial effusion and cardiac tamponade
Thoracic aortic aneurysm
Abdominal aortic aneurysm (AAA)
Aortic dissection
Aneurysm
Endarterectomy
Vascular diseases of the aorta and limbs
Peripheral arterial disease
Acute limb ischemia
Carotid artery stenosis
Chronic venous disease
Cardiomyopathy
Cardiomyopathy
> Table of Content | 6
S01: Cardiovascular Medicine
Theme
Topic
Antiarrhythmic drugs
Antiplatelet agents
Oral anticoagulants
Parenteral anticoagulation
Antiadrenergic agents
Beta blockers
Calcium channel blockers (CCB)
Renin-angiotensin-aldosterone system inhibitors
Cardiac drugs
Amiodarone
Nitrates
Phosphodiesterase inhibitors
Cardiac glycosides (Digitalis)
Diuretics
Parasympathomimetic drugs
Muscarinic antagonists
Sympathomimetic drugs
Statins
> Table of Content | 7
S02: Respiratory Medicine
Theme
Topic
Approach to the patient with dyspnea
Pulmonary examination
Approach to the patient with cough
Cough
Airway management and ventilation
Airway management and ventilation
Asthma
Chronic obstructive pulmonary disease
Obstructive Pulmonary Diseases
Bronchiectasis
Cystic Fibrosis
Pneumonia
Respiratory infections
Acute bronchitis
Tuberculosis
Lung cancer
Lung cancer
Interstital pulmonary disease
Interstitial lung disease
Pulmonary embolism
Pulmonary vascular disease
Deep vein thrombosis
Pulmonary hypertension and cor pulmonale
Pulmonary hypertension and cor pulmonale
Sarcoidosis
Asbestosis
Pneumoconiosis
Silicosis
Rare pneumoconioses
Atelectasis
Atelectasis
Acute respiratory distress syndrome
Acute respiratory distress syndrome
Pleura and mediastinal disorders
Pneumothorax
Pleural effusion
Upper airway disease
Obstructive sleep apnea
> Table of Content | 8
S02: Respiratory Medicine
Theme
Topic
Hypersensitivity and anaphylactic reactions
Allergies, anaphylaxis
Hypersensitivity pneumonitis
Shock
Pulmonary function testing
Other
Arterial blood gas analysis and pulse oximetry
Beta-2 adrenergic agonists
> Table of Content | 9
S03: ENDOCRINOLOGY
Theme
Topic
Principles of endocrinology
General endocrinology
Diabetes mellitus
Hyperglycemic crises
Hypoglycemia
Diabetes mellitus
Antidiabetic drugs
Inpatient management of hyperglycemia
Insulin
Lipid Disorders
Dyslipidemias and disorders of lipoprotein metabolism
Statins
Second-line lipid-lowering agents
Obesity
Metabolic syndrome
Thyroid gland and parathyroid glands
Antithyroid drugs
Goiter
Thyroid antibodies
Hyperthyroidism
Graves disease
Thyroid disorders
Hypothyroidism
Hashimoto’s thyroiditis
Subacute thyroiditis
Thyroid nodules
Thyroid cancer (Thyroid carcinoma)
Thyroid surgery
Parathyroid diseases
Hyperparathyroidism
Hypoparathyroidism
> Table of Content | 10
S03: ENDOCRINOLOGY
Theme
Topic
Adrenal diseases
Adrenal insufficiency
Primary hyperaldosteronism/Conn syndrome
Cushing’s syndrome
Congenital adrenal hyperplasia
Pheochromocytoma
Metabolic bone disorders
Osteomalacia and rickets
Osteoporosis
Bisphosphonates
Laboratory evaluation of bone disease
Paget disease of bone
Hypopituitarism
Hypothalamus and pituitary disease
Hyperprolactinemia
Acromegaly
Pituitary adenoma
Hypogonadism
Hypogonadism
Multiple endocrine neoplasia
Multiple endocrine neoplasia
Syndrome of inappropriate antidiuretic hormone
secretion (SIADH) and diabetes insipidus
Breast disorders
Syndrome of inappropriate antidiuretic hormone secretion
(SIADH)
Diabetes insipidus
Breast cancer
Benign breast conditions
Other
Insulinoma
Glucocorticoids
> Table of Content | 11
S04: GASTROENTEROLOGY
Theme
Topic
Nausea and vomiting
Approach to the patient with nausea and vomiting
Case 5: Nausea
Approach to the acute abdomen
Acute abdomen
Approach to the patient with dysphagia
Case 22: Problems with swallowing
Esophagus
Esophageal cancer
Esophageal perforation
Esophageal barium swallow
Achalasia
Esophageal diverticula
Esophagus, stomach and duodenum
Gastroesophageal reflux disease
Peptic ulcer disease
Atrophic gastritis
Gastrinoma (Zollinger-Ellison syndrome)
Gastric cancer
Boerhaave syndrome
Acute pancreatitis
Diseases of the Pancreas
Chronic pancreatitis
Pancreatic Carcinoma
> Table of Content | 12
S04: GASTROENTEROLOGY
Theme
Approach to the patient with digestive bleeding
Topic
Gastrointestinal bleeding
Mallory-Weiss syndrome
Case 8: Altered bowel habits
Acute appendicitis
Crohn disease
Ulcerative colitis
Irritable bowel syndrome
Colorectal cancer
Colonic polyps
Lynch syndrome (Hereditary nonpolyposis colon cancer)
Bowel obstruction
Bowel surgery
Diseases of the Small and Large Intestines
Abdominal hernias
Inguinal hernia
Femoral hernia
Internal hernia
Congenital diaphragmatic hernias
Acquired diaphragmatic hernia
Malabsorption
Coeliac disease
Lactose intolerance
Intestinal ischemia
> Table of Content | 13
S04: GASTROENTEROLOGY
Theme
Topic
Diarrhea
Food poisoning
Bacterial gastroenteritis
Norovirus infection
Diarrhea, gastroenteritis and food borne
gastric infections
Rotavirus infection
Botulism
Diarrheagenic E. coli
Clostridium difficile infection
Amebiasis
Giardiasis
Rectal prolapse
Hemorrhoids
Thrombosed external hemorrhoid
Anorectal Disorders
Anal fissures
Anal abscess and fistula
Anal cancer
Pilonidal cyst
Approach to the jaundiced patient
Jaundice and cholestasis
Cirrhosis
Alcoholic liver disease
Ascites
Diseases of the liver
Portal hypertension
Wilson disease
Hemochromatosis
Autoimmune hepatitis
> Table of Content | 14
S04: GASTROENTEROLOGY
Theme
Topic
Hepatitis A
Hepatitis B
Diseases of the liver
Hepatitis C
Hepatocellular carcinoma
Benign Liver tumors and hepatic cysts
Pyogenic liver abscess
Cholelithiasis, choledocholithiasis, cholecystitis, and cholangitis
Primary biliary cholangitis
Gallbladder and biliary tract diseases
Primary sclerosing cholangitis
Cholangiocarcinoma
Inherited hyperbilirubinemia (Gilbert's syndrome)
Proton pump inhibitors
Meckel diverticulum
Other
Pancreatic and hepatic surgery
Carcinoid tumor
> Table of Content | 15
S05: RENAL MEDICINE
Theme
Topic
Diagnostic evaluation of the kidney and urinary tract
Approach to the patient with urinary abnormalities
Dehydration
Sodium disorders
Disorders of potassium balance
Fluid and electrolyte imbalances
Disorders of calcium balance
Syndrome of inappropriate antidiuretic hormone secretion
(SIADH)
Diabetes insipidus
Acute kidney injury
Pyelonephritis
Urinary tract infections
Acute kidney and urinary tract diseases
Urethritis
Nephrolithiasis
Hematuria
Chronic kidney disease
Renal cell carcinoma
Urothelial cancer
Urinary incontinence
Stress incontinence
Chronic kidney and urinary tract diseases
Urge incontinence
Urinary retention
Urinary tract obstruction
Vesicoureteral reflux
Retroperitoneal fibrosis
> Table of Content | 16
S05: RENAL MEDICINE
Theme
Topic
Glomerular diseases
IgA nephropathy (Berger disease)
Poststreptococcal glomerulonephritis
Glomerular diseases
Rapidly progressive glomerulonephritis
Nephrotic syndrome
Nephritic syndrome
Proteinuria
Renal Artery Stenosis
Renal Artery Stenosis
Congenital anomalies of the kidneys
Hereditary renal disorders
Polycystic Kidney Disease
Renal tubular disorders
Tubulointerstitial diseases
Tubulointerstitial diseases
Benign prostatic hyperplasia
Prostate
Prostatitis
Prostate cancer
Bladder exstrophy, abnormalities of the male urethra,
and webbed penis
Disorders of the glans penis and foreskin
Scrotal abnormalities
Epididymitis
Male reproductive system
Testicular tumors
Carcinoma of the penis
Genitourinary trauma
Testicular torsion
Priapism
> Table of Content | 17
S05: RENAL MEDICINE
Theme
Topic
Penile fracture
Male reproductive system
Erection and ejaculation disorders
Semen analysis
Edema
Renal replacement therapy
Other
Diagnostic investigations in urology
Diuretics
> Table of Content | 18
S06: HEMATOLOGY
Theme
Topic
Basics of haematology
Basics of hematology
Approach to the patient with adenopathy
and splenomegaly
Splenomegaly
Lymphadenopathy
Anemia
Iron deficiency anemia
Hemolytic anemia
Hereditary spherocytosis
Anemias
Glucose-6-phosphate dehydrogenase deficiency
Sickle cell anemia
Vitamin B12 deficiency
Porphyrias
Hemolytic uremic syndrome (HUS)
Hodgkin lymphoma
Lymphomas
Non-Hodgkin lymphomas
MALT lymphoma
Acute leukemia
Leukemias
Chronic myeloid leukemia
Chronic lymphocytic leukemia
Hemostasis and bleeding disorders
Hemophilia
Coagulation and bleeding disorders
Hypercoagulable states
Disseminated intravascular coagulation
Haemoglobinopathies
Thalassemia
Myelodysplastic syndromes
Myelodysplastic syndromes
Polycythemia vera
Myeloma and plasma cell disorders
Multiple myeloma
> Table of Content | 19
S06: HEMATOLOGY
Theme
Topic
Blood products
Transfusion
Thrombocytopenia
Platelet and vascular wall disorders
Thrombotic thrombocytopenic purpura
Myeloproliferative neoplasms
Myeloproliferative neoplasms
Amyloidosis
Amyloidosis
Antiplatelet agents
Parenteral anticoagulation
Oral anticoagulants
Erythrocyte morphology and hemoglobin
Other
Myeloproliferative neoplasms
Mycosis fungoides
(Cutaneous T-cell lymphoma)
Antiphospholipid syndrome
Asplenia
> Table of Content | 20
S07: INFECTIOUS DISEASES
Theme
Topic
Bacteria overview
Principles of microbiology
General mycology
Approach to the patient with fever
Fever and inflammation
The flu
Influenza
Sepsis and septic shock
Sepsis
Shock
HIV/AIDs
Human immunodeficiency virus (HIV)
HIV-associated conditions
Hospital acquired infections
Nosocomial infections
Syphilis
Syphilis
Sexually transmitted infections
Candidiasis
Gonorrhea
Chancroid
Sexually transmitted diseases
Herpes simplex virus infections
Cytomegalovirus infection
Chlamydia infections
Pelvic inflammatory disease
Granuloma inguinale
Legionnaires disease
Legionellosis
Collection of zoonotic diseases
Lyme disease (Borreliosis)
Typhoid fever, Paratyphoid fever
Leptospirosis
Zoonoses and arthropod-borne infections
Diphtheria
Listeriosis
> Table of Content | 21
S07: INFECTIOUS DISEASES
Theme
Topic
Dengue
Malaria
Zoonoses and arthropod-borne infections
Toxoplasmosis
Yellow fever
Zika virus infection
Immunosuppressants
Immunosuppression
Pneumocystis pneumonia
Transplantation
Aspergillosis
Mononucleoside syndromes
Infectious mononucleosis/Epstein Barr Virus
Traveler’s diarrhea
Traveller’s diseases
Immunizations for travel
Vaccination
Immunization schedule
Overview of antibiotic therapy
Antiviral agents
Other
Antifungals
Chloroquine and hydroxychloroquine
Staphylococcal diseases
Finger infections
Tetanus
> Table of Content | 22
S08: NEUROLOGY
Theme
Topic
Neurological examination
Neurological examination
Headache
Migraine
Tension headaches
Approach to the patient with headache
Cluster headache
Elevated intracranial pressure and brain herniation
Dissection of the carotid and the vertebral artery
Approach to the patient with syncope
Syncope
Lumbar Puncture
Lumbar puncture
Cranial nerve palsies
Cranial nerve disorders
Trigeminal neuralgia
Facial nerve palsy/Bell palsy
Disorders of the visual pathway
Disorders of the visual pathway
Parkinson disease
Parkinson-plus syndromes
Medication for Parkinson disease
Huntington‘s disease
Movement disorders
Dystonia
Tremor
Tourette syndrome
Spasticity
Cerebellum
Cerebellar syndromes
Cerebellar disorders
Wernicke encephalopathy and Korsakoff syndrome
Spino-cereballar ataxia
> Table of Content | 23
S08: NEUROLOGY
Theme
Topic
Meningitis
Infections of nervous system
Herpes simplex encephalitis
Brain abscess
Complete spinal cord injury
Spinal disorders
Incomplete spinal cord syndromes
Syringomyelia
Spinal stenosis
Bulbar palsy and pseudobulbar palsy
Carpal tunnel syndrome
Diabetes mellitus (diabetic neuropathy)
Median nerve neuropathy
Peripheral neuropathy
Neuralgic amyotrophy
Peripheral nerve injuries
Polyneuropathy
Radial neuropathies
Ulnar nerve entrapment
Motor neuron diseases
Amyotrophic lateral sclerosis
Spinal muscular atrophy
Neurodegenerative
Hereditary spastic paraplegia
Multiple sclerosis
Multiple sclerosis
Neuromuscular junction diseases
Myasthenia gravis
Botulism
Guillain-Barre syndrome
Guillain-Barré syndrome
Muscular dystrophies
Progressive muscular dystrophies
Myopathies
Myotonic syndromes
Pain syndromes
Complex regional pain syndrome
> Table of Content | 24
S08: NEUROLOGY
Theme
Topic
Seizure disorders (Epilepsy)
Seizure disorders and epilepsy
Focal seizures and syndromes
Anticonvulsant drugs
Narcolepsy
Sleep disorders
Restless legs syndrome
Cerebrovascular system
Stroke
Locked-in syndrome
Wallenberg syndrome (lateral medulla syndrome)
Cerebral aneurysms
Cerebrovascular system
Cerebral venous thrombosis
Carotid-cavernous fistula
Epidural hematoma
Subdural hematoma
Subarachnoid hemorrhage
Intracerebral hemorrhage
Traumatic brain injury
Traumatic brain injury
Brain tumours
Brain tumours
Astrocytoma
Meningioma
Acoustic neuroma
Elevated intracranial pressure and brain herniation
Intracranial pathology
Idiopathic intracranial hypertension
Hydrocephalus
Hydrocephalus
> Table of Content | 25
S08: NEUROLOGY
Theme
Topic
Rare neurological diseases
Transient global amnesia
Other
Skull base syndromes
Creutzfeldt-Jakob disease
Myelopathy
> Table of Content | 26
S09: ONCOLOGY
Theme
Topic
Principles of oncology
General oncology
Disorders of calcium balance
Oncological emergencies
Superior Vena Cava Syndrome
Spinal cord compression
Brain metastases
Disordered cell growth
Tumor markers
Palliation
Overview of palliative medicine
Chemotherapeutic agents
Principles of cancer treatment
Opioids
Antiemetics
Paraneoplastic syndromes
Paraneoplastic syndromes
> Table of Content | 27
S10: DERMATOLOGY
Theme
Topic
Principles of dermatology
Principles of dermatology
Benign skin lesions
Collection of dermatological disorders
Precancerous skin lesions
Melanoma
Skin cancers
Squamous cell carcinoma
Basal cell carcinoma (Basalioma)
Skin and soft tissue infections
Gas gangrene (Clostridial myonecrosis)
Shingles
Molluscum contagiosum
Impetigo
Skin and soft tissue infections
Staphylococcal scalded skin syndrome
Dermatophyte infections
Tinea versicolor (Pityriasis versicolor)
Scabies
Lice infestation
Erythrasma
Atopic dermatitis
Contact dermatitis
Dermatitis (Eczema)
Seborrheic dermatitis
Stasis Dermatitis
Lichen Simplex Chronicus
Wound treatment
Wounds
Wound healing
Burns
Burns
> Table of Content | 28
S10: DERMATOLOGY
Theme
Topic
Acne vulgaris
Acneiform Eruptions
Rosacea
Lichen planus
Papulosquamous Diseases
Pityriasis rosea
Psoriasis
Autoimmune blistering diseases
Vesiculobullous Diseases
Porphyrias
Ichthyosis
Heritable Disorders
Vitiligo
Neurocutaneous syndromes
Stevens-Johnson syndrome
Aphthous stomatitis
Alopecia
Other
Photodermatoses
Angioedema
Erythema nodosum
Erythema multiforme
> Table of Content | 29
S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme
Topic
Ocular trauma
Traumatic eye injuries
Eye and orbit
Orbit
Orbital disorders
Lacrimal apparatus
Diseases of the lacrimal apparatus
Lids and lashes
Inflammation of the eyelids
Conjunctivitis
Conjunctiva
Pterygium
Sclera
Scleritis and episcleritis
Cornea
Corneal disorders
Diseases of the uvea
Uveal tract
Uveal melanoma
Diseases of the lens
Lens
Cataract
Diseases of the vitreous body
Vitreous
Endophthalmitis
Diseases of the retina
Retinal vessel occlusion
Retina
Retinal detachment
Age-related macular degeneration
Glaucoma
Glaucoma
Pupils
Physiology and abnormalities of the pupil
Horner syndrome
Opthalmology miscellaneous
Keratitis
Ocular motility disorders and strabismus
> Table of Content | 30
S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme
Topic
Hearing loss
The Ear
Otitis externa (Swimmer’s ear)
Acute otitis media (Middle ear infection)
Ear
Chronic otitis media
Cholesteatoma
Otosclerosis
Ménière disease
Tinnitus
Case 40: Dizziness
Benign paroxysmal positional vertigo
Dizziness and Vertigo
Vestibular Neuronitis (labyrinthitis)
Acoustic neuroma (vestibular schwannoma)
Phobic postural vertigo
Rhinosinusitis
Rhinitis
Sinusitis
Nose
Epistaxis
Nasal papilloma
> Table of Content | 31
S11: HEAD AND NECK / EYE / EAR NOSE
AND THROAT
Theme
Topic
Acute tonsillitis
Larynx
Laryngitis
Throat
Laryngeal carcinoma
Pharyngeal cancer
Juvenile nasopharyngeal angiofibroma
Adenoid hypertrophy
Miscellaneous ear, nose, and throat disorders
Miscellaneous ear, nose, and throat disorders
Diseases of the salivary glands
Head and Neck Examination
Head and Neck
Overview of head and neck region
Deep neck infections
Congenital neck masses
> Table of Content | 32
S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme
Topic
Adaptive immune system
Principles of immunology and rheumatology
Autoantibodies in rheumatic diseases
Immunosuppressants
Rheumatoid arthritis
Systemic lupus erythematosus
Antiphospholipid syndrome
Systemic connective tissue disease
Systemic sclerosis (Scleroderma)
Inflammatory myopathies (Myositis)
Sjögren’s Syndrome
Connective tissue diseases
Seronegative spondyloarthropathies
Ankylosing spondylitis
Seronegative rheumatic disease
Reactive arthritis (Reiter syndrome)
Psoriasis
Vasculitides
Kawasaki disease
Giant cell arteritis (Temporal arteritis)
Vasculitides
Granulomatosis with polyangiitis
(Wegener granulomatosis)
Thromboangiitis obliterans
Raynaud phenomenon
Henoch-Schonlein purpura
Gout and other microcrystalline arthropathies
Gout and hyperuricemia
Osteoarthritis
Degenerative joint disease
Osteoarthritis of the hip and knee
Fibromyalgia
Non-articular rheumatism
Polymyalgia rheumatica
> Table of Content | 33
S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme
Topic
Bone tumours
Benign bone tumors
Malignant bone tumors
Compartment syndrome
General principles of fractures
Compartment syndrome
General principles of fractures
Conservative treatment of fractures
(Conservative fracture management)
Shoulder, axilla, and brachial plexus
Shoulder dislocation
Shoulder
Soft tissue lesions of the shoulder
Biceps tendon tear
Clavicle
Clavicle fracture
Upper arm and elbow
Humerus fracture
Humerus and elbow
Insertional tendiopathy (epicondylitis)
Elbow dislocation
Radial head subluxation (Pulled elbow)
Forearm, wrist and hand
Scaphoid fracture
Forearm, wrist and hand
Distal radius fractures
Finger injuries
Dupuytren’s contracture
Vertebral fractures
Spondylolisthesis
Spine
Degenerative disc disease
Torticollis
Pelvis
Pelvic fracture
Hip
Hip fractures
> Table of Content | 34
S12: MUSCULOSKELETAL / ORTHOPAEDICS /
RHEUMATOLOGY
Theme
Topic
The leg, ankle and foot
Femur
Femoral shaft fracture
Osteonecrosis of the femoral head
Patellar dislocation
Knee and patellar
Knee ligament injuries
Meniscus tear (Meniscus rupture)
Tibia
Tibial fracture
Ankle fracture
Ankle and foot
Achilles tendon rupture
Foot deformities
Sports injuries
Sports injuries
Pediatric fractures
Pediatric fractures
Septic arthritis (Infectious arthritis)
Bone and joint infections
Osteomyelitis
Collection of orthopedic conditions
Thoracic outlet syndrome
Other (orthopedics)
Osteochondritis dissecans
Tenosynovitis
> Table of Content | 35
S13: OBSTETRICS & GYNAECOLOGY
Theme
Topic
Menopause, urogynaecology and prolapse
Diagnostic procedures in gynecology
Menopause
Pelvic organ prolapse
Stress incontinence
Urinary incontinence
Urinary tract infections
Anomalies of the female genital tract
Oncology and gynaecological surgery
Human papillomavirus infection
Cervical cancer (Cervical carcinoma)
Breast cancer
Vulvar and vaginal cancer
Ovarian tumors
Menstrual cycle and menstrual cycle abnormalities
Hypogonadism
Menstrual cycle, puberty and hormones
Estrogen and associated diseases
Disorders of sex development
Endometriosis
Endometrial cancer
Uterine leiomyoma (Fibroids)
Polycystic ovary syndrome (PCOS)
Vaginal bleeding
Pregnancy loss
Ectopic pregnancy
Vulvovaginitis
Sexually transmitted infections
> Table of Content | 36
S13: OBSTETRICS & GYNAECOLOGY
Theme
Topic
Infertility
Nonhormonal contraception
Contraception, preconception and infertility
Hormonal contraceptives
Prenatal care
Pregnancy
The placenta, umbilical cord, and amniotic sac
Hypertensive pregnancy disorders
Gestational diabetes mellitus
Gestational trophoblastic disease
Antenatal care, fetal wellbeing and medical
disorders in pregnancy
Placental insufficiency
Multiple pregnancy
Intrauterine growth restriction
Pharmacotherapy during pregnancy
Chorioamnionitis, neonatal infection and omphalitis.
Childbirth
Mechanics of childbirth
Labour and birthing
Uterine rupture
Preterm labor and birth
Congenital TORCH infections
Birth traumas
Obstetric emergencies
Postpartum hemorrhage
Antepartum hemorrhage
Postpartum period
Puerperium
Prenatal and postnatal physiology
> Table of Content | 37
S14: PSYCHIATRY
Theme
Topic
Autism spectrum disorder
Tourette syndrome
Neurodevelopmental disorders
Emotional and behavioral disorders in children and adolescents
Attention deficit hyperactivity disorder
Personality disorders
Personality disorders
Disruptive, impulse-control, and conduct disorders
Psychosomatic
Somatic symptom and related disorders
Schizophrenia
Delusional disorder
Psychosis
Bipolar disorder
Lithium
Antipsychotics
Major depressive disorder
Anxiety disorders
Depressive and anxiety disorders
Antidepressants
Suicidality
Obsessive compulsive disorders
Obsessive-compulsive disorder
Feeding and eating disorders
Eating disorders
Trauma- and stressor-related disorders
Trauma- and stressor-related disorders
Dissociative disorders
Dissociative disorders
Elimination disorders
Elimination disorders
Sleep wake disorders
Sleep disorders
Sedative hypnotic drugs
> Table of Content | 38
S14: PSYCHIATRY
Theme
Topic
Sexual dysfunctions
Sexuality and sexual medicine
Alcohol use disorder (Alcoholism)
Substance related and addictive disorders
Substance-related and addictive disorders
Wernicke encephalopathy and Korsakoff syndrome
Major neurocognitive disorder
Delirium
Alzheimer’s disease
Neurocognitive disorders
Vascular dementia
Frontotemporal dementia
Parkinson-plus syndromes
Psychotherapy and defense mechanisms
Other
Electroconvulsive therapy (ECT)
Anticonvulsant drugs
> Table of Content | 39
S15: PEDIATRIC MEDICINE
Theme
NEONATOLOGY
The newborn infant
Birth traumas
Neonatal respiratory distress syndrome
Teratogenic birth defects
Assessment and care and major problems of
the newborn
Intrauterine Growth Restriction
Congenital visceral malformations
Hemolytic disease of the fetus and newborn
Vitamin K deficiency bleeding of the newborn
Sudden infant death syndrome
Neonatal jaundice
Neonatal jaundice (Icterus neonatorum)
Neonatal screening
The newborn infant
Congenital TORCH infections
Infectious diseases in pregnancy affecting the newborn
HIV in pregnancy
Perinatal hepatitis B
Hypertensive pregnancy disorders
Pregnancy disorders affecting the newborn
Gestational diabetes mellitus
Hyperthyroidism in pregnancy
Neonatal sepsis
Chorioamnionitis, neonatal infection, and omphalitis
CHILD DEVELOPMENT, MILESTONES, AND GROWTH
Child development and milestones
Child development and milestones
> Table of Content | 40
S15: PEDIATRIC MEDICINE
Theme
GENERAL PAEDIATRICS
Normal growth
Child development and milestones
National program for Child and Youth Health
See recommended resources
National Vaccination Program
Vaccination
Immunization schedule
CARDIOLOGY
Congenital heart defects
Acyanotic congenital heart defects
Cyanotic congenital heart defects
HAEMATOLOGY/ONCOLOGY
Anaemia
Anemia
Thalassemia
Diagnostic approach and referral criteria
for paediatric neoplasia
Acute leukemia
Neuroblastoma
Common paediatric tumours
Wilms tumour (Nephroblastoma)
Retinoblastoma
ENDOCRINOLOGY, NUTRITION AND GROWTH
Puberty disorders
Puberty
Disorders of sex development
Tall stature and abnormally rapid growth
Disordered growth
Metabolic syndrome
Short stature
Diabetes Mellitus
Diabetes mellitus
> Table of Content | 41
S15: PEDIATRIC MEDICINE
Theme
INFECTIOUS DISEASES
Measles
Mumps
Scarlet fever (Second disease)
Rubella
Fifth disease (Erythema infectiosum)
Roseola infantum
Chickenpox
Atopic dermatitis
Seborrheic dermatitis
Dermatology and rashes
Acne vulgaris
Herpes simplex virus infections
Molluscum contagiosum
Impetigo
Staphylococcal scalded skin syndrome
Dermatophyte infections
Tinea versicolor (Pityriasis versicolor)
Scabies
Lice infestation
Approach to the child with fever
Fever and inflammation
Febrile seizures (Febrile seizure)
Sepsis
Sepsis
> Table of Content | 42
S15: PEDIATRIC MEDICINE
Theme
NEUROLOGY
Neurological infections
Meningitis
Poliomyelitis
Craniosynostosis
Neurology
Hydrocephalus
Craniovertebral junction anomalies
Neural tube defects
Seizure disorders
Seizure disorders and febrile convulsions
Generalized epilepsy in childhood
Febrile seizures (Febrile seizure)
CHILD PSYCHIATRY AND NEURODEVELOPMENT
Child development and milestones
Disruptive, impulse-control, and conduct disorders
Child psychiatry and neurodevelopmental disorders
Chromosomal aberrations
Autism spectrum disorder
Attention deficit hyperactivity disorder
Cerebral Palsy
Maltreatment in child and youth
Child maltreatment
> Table of Content | 43
S15: PEDIATRIC MEDICINE
Theme
PULMONOLOGY
Bronchiolitis
Croup
Respiratory tract infections
Pertussis
Acute bronchitis
Recurrent wheezing and asthma
Urticaria, angioedema and anaphylaxis
Asthma
Hypersensitivity reactions
Angioedema
Obstructive sleep apnoea
Obstructive sleep apnoea
Food allergy
Food allergies
Cystic fibrosis
Cystic fibrosis
GASTROENTEROLOGY
Hypertrophic pyloric stenosis
Gastroesophageal reflux
Acute appendicitis
Esophageal atresia
Approach to the vomiting child
Duodenal atresia and stenosis
Hirschsprung’s disease
Necrotizing enterocolitis
Intussusception
Volvulus and intestinal malrotation
Meckel diverticulum
Inguinal hernia
Approach to children with acute abdominal pain
Testicular torsion
Ovarian torsion
Henoch-Schonlein purpura
> Table of Content | 44
S15: PEDIATRIC MEDICINE
Theme
GASTROENTEROLOGY
Approach to the constipated child
Constipation
Diarrhea
Malabsorption
Celiac disease
Approach to the child with chronic diarrhoea
and malabsorption
Crohn disease
Ulcerative colitis
Lactose intolerance
Irritable bowel syndrome
Bacterial gastroenteritis
Diarrheagenic E. coli
Acute gastroenteritis
Rotavirus infection
Diarrhea
Approach to the dehydrated child
Dehydration
OPTHALMOLOGY AND ENT
Conjunctivitis
Ophthalmology
Strabismus
Orbital cellulitis
Acute otitis media
Ear
Chronic otitis media
Otitis externa
Acute tonsilitis
Laryngitis
Nose and throat
Epiglottitis
Sinusitis
Rhinitis
> Table of Content | 45
S15: PEDIATRIC MEDICINE
Theme
NEPHROLOGY
Urinary tract infections
Urinary tract infections
Nephrotic syndrome
Nephrotic syndrome
Congenital anomalies of the kidneys
Renal and urinary tract malformations
Bladder exstrophy, abnormalities of the male urethra,
and webbed penis
Vesicoureteral reflux
Nephritic syndrome
Glomerulonephritis
Poststreptococcal glomerulonephritis
Henoch-Schönlein purpura
Enuresis
Elimination disorders
MUSCULOSKELETAL
Developmental dysplasia of the hip
Legg-Calvé-Perthes disease
Slipped capital femoral epiphysis
Orthopedics
Osgood Schlatter disease
Transient synovitis
Juvenile idiopathic arthritis
Idiopathic scoliosis
Osteomyelitis and infectious arthritis
Septic arthritis
Osteomyelitis
Muscular dystrophy
Progressive muscular dystrophies
Muscular atrophy
Spinal muscular atrophy
OTHERS
Cardiopulmonary resuscitation
Paediatric basic life support
Foreign body aspiration (FBA)
Parenteral fluid therapy
> Table of Content | 46
S15: PEDIATRIC MEDICINE
Theme
CONGENITAL AND INHERITED DISORDERS
Basics of human genetics
Down syndrome (Trisomy 21)
Ehlers-Danlos syndrome and Marfan syndrome
Inherited hyperbilirubinemia
Inborn errors of carbohydrate metabolism
Congenital immunodeficiency disorders
Cleft lip and cleft palate (Cleft lip)
Congenital adrenal hyperplasia
Inborn errors of metabolism
Rare inherited syndromes
Choanal atresia
Neurocutaneous syndromes
> Table of Content | 47
S16: NUTRITION / METABOLISM
Theme
Topic
Specialised nutrition support
Vitamins
Nutrition
Vitamin B12 deficiency
Folate deficiency
Malabsorption
Inborn errors of metabolism
Lipids and fat metabolism
Metabolism
Inborn errors of carbohydrate metabolism
Glycogen metabolism
Glycolysis and gluconeogenesis
Intravenous fluid therapy
Electrolyte repletion
Normal fluid and electrolyte imbalance
Sodium disorders
Potassium disorders
Calcium disorders
Acid-base balance
Acid base disorders
> Table of Content | 48
S17: CLINICAL PHARMACOLOGY
Theme
Topic
Fundamentals of pharmacology
Fundamentals of pharmacology
Salicylate toxicity
Metal toxicity
Toxicity and poisoning
Organic solvent toxicity
Poisoning
> Table of Content | 49
S18: CLINICAL IMMUNOLOGY
Theme
Topic
Lymphatic system
Lymphatics
Lymphatic techniques
Lymphadenopathy
Transplantation
Transplantation
Adaptive immune system
Immunology
Innate immune system
Congenital immunodeficiency disorders
> Table of Content | 50
S19: CRITICAL CARE/ANAESTHESIA/
EMERGENCY MEDICINE
Theme
Topic
Management of trauma patients
Penetrating trauma
Blunt trauma
Splenic rupture
Trauma
General treatment of fractures
Nonthrombotic embolism
Rhabdomyolysis and crush syndrome
Compartment syndrome
Airway management and ventilation
Perioperative management
Surgery
Laparoscopic surgery
Airway management and ventilation
Airway management and ventilation
Pain management
Opioids
Local anesthetic agents
Local and regional anesthesia
Anaesthesia
Non-opioid analgesics
Inhalational anesthetics
Intravenous anaesthetics
Skeletal muscle relaxants
Benzodiazepines
Malignant hyperthermia
Other
Parenteral fluid therapy
Hypothermia and frostbite
> Table of Content | 51
S20: PUBLIC HEALTH / LAW / ETHICS
Theme
Topic
Investigations
Laboratory medicine
Death
Grief and end-of-life counseling
Overview of palliative medicine
Medical law and ethics
Patient communication and counseling
Principles of medical law and ethics
Quality and safety
Epidemiology
Epidemiology
Infection prevention and control
If you have completed this study guide, you will have covered all of the requirements for the ‘Medical Expert’
objectives outlined by the Medical Council of Canada. However, you will also need to consult other resources
for Canadian medical ethics, laws, and healthcare systems. To do this, you will find a list of resources here.
Specifically, you should supplement this Study Guide with resources covering these topics:
Population Health and Its Determinants
Concepts of Health and Its Determinants
Disaster Preparedness, Emergency Response, and Recovery
Assessing and Measuring Health Status at the Population Level
Interventions at the Population Level
Administration of Effective Health Programs at the Population Level
Outbreak Management
Environment
Health of Special Populations
Work-related Health Issues
Indigenous Health
Legal, Ethical and Organizational Aspects of Medicine
Consent
Truth Telling
Negligence
Confidentiality
Legal System
> Table of Content | 52