abiotic factors = non-living conditions in a habitat activation energy = the energy required to initiate a reaction. active site = area of an enzyme with a shape complementary to a specific substrate, allowing the enzyme to bind a substrate with specificity. active transport = movement of particles across a plasma membrane against a concentration gradient. Energy is required. (ATP) adenosine diphosphate (ADP) = a nucleotide composed of a nitrogenous base (adenine), a pentose sugar and two phosphate groups. Formed by the hydrolysis of ATP, releasing a phosphate ion and energy. adenosine triphosphate (ATP) = a nucleotide composed of a nitrogenous base (adenine), a pentose sugar and three phosphate groups. The universal energy currency for cells. agglutinins = chemicals (antibodies) that cause pathogens to clump together so they are easier for phagocytes to engulf and digest.(caused by cross linking by antibodies that have a number of binding sites) alleles = different versions of the same gene. amino acids = monomer used to build polypeptides and thus proteins anabolism (anabolic) = reactions of metabolism that construct molecules from smaller units. These reactions require energy from the hydrolysis of ATP. analogous structures = structures that have adapted to perform the same function but have a different origin. anaphase = third stage of mitosis when chromatids are separated to opposite poles of the cell. antibiotic-resistant bacteria = bacteria that undergo mutation to become resistant to an antibiotic and then survive to increase in number. antibiotics = a chemical or compound that kills or inhibits the growth of bacteria antibodies = Y-shaped glycoproteins made by B cells of the immune system in response to the presence of an antigen. antigen = identifying chemical on the surface of a cell that triggers an immune response antigen−antibody complex = the complex formed when an antibody binds to an antigen. antigen-presenting cell (APC) = a cell that displays foreign antigens complexed with major histocompatibility complexes on their surface plasma membranes, so it can be recognised by other cells antisense strand 'lagging strand' = the strand of DNA that runs 3' to 5' and is complementary to the sense strand. It acts as a template strand during transcription. anti-toxins = chemicals (antibodies) that bind to toxins produced by pathogens so they no longer have an effect. apoplast = the cell walls and intercellular spaces of plant cells. apoplast route = movement of substances through the cell walls and cell spaces by diffusion and into cytoplasm by active transport. arrhythmia = an abnormal rhythm of the heart. artefacts = objects or structures seen through a microscope that have been created during the processing of the specimen. artificial active immunity = immunity which results from exposure to a safe form of a pathogen, for example, by vaccination. artificial passive immunity = immunity which results from the administration of antibodies from another animal against a dangerous pathogen. asexual reproduction = the production of genetically identical offspring from a single parent. assimilates = the products of photosynthesis that are transported around a plant, e.g., sucrose atrial fibrillation = an abnormal rhythm of the heart when the atria beat very fast and incompletely. atrio-ventricular node (AVN) = stimulates the ventricles to contract after imposing a slight delay to ensure atrial contraction is complete. autoimmune disease = a condition or illness resulting from an autoimmune response. autoimmune response = response when the immune system acts against its own cells and destroys healthy tissue in the body. autotrophic = organisms that acquire nutrients by photosynthesis. B effector cells = B lymphocytes that divide to form plasma cell clones B lymphocytes (B cells) = lymphocytes which mature in the bone marrow and that are involved in the production of antibodies B memory cells = B lymphocytes that live a long time and provide immunological memory of the antibody needed against a specific antigen. belt transect = two parallel lines are marked along the ground and samples are taken of the area at specified points. Benedict's reagent = an alkaline solution of copper(II)sulfate used in the chemical tests for reducing sugars and non-reducing sugars. A brick-red precipitate indicates a positive result. beta pleated sheet = sheet-like secondary structure of proteins binomial nomenclature = the scientific naming of a species with a Latin name made of two parts − the first indicating the genus and the second the species. biodiversity = the variety of living organisms present in an area biuret test = the chemical test for proteins; peptide bonds form violet coloured complexes with copper ions in alkaline solutions. Bohr effect = the effect of carbon dioxide concentration on the uptake and release of oxygen by haemoglobin bradycardia = a slow heart rhythm of below 60 beats per minute breathing rate = the number of breaths (inhalation and exhalation) taken per minute. bulk transport = a form of active transport where large molecules or whole bacterial cells are moved into or out of a cell by endocytosis or exocytosis bundle of his = conducting tissue composed of purkyne fibres that passes through the septum of the heart alpha-glucose = glucose in which the hydrogen atom on carbon no.1 projects above the plane of the ring ab initio protein modelling = a model is built based on the physical and electrical properties of the atoms in each amino acid in the sequence accuracy = how close a measured or calculated value is to the true value active immunity = where the immune system is activated and manufactures its own antibodies adaption = a characteristic that enhances survival in the habitat adhesion = the attraction between water molecules and the walls of the xylem vessels affinity = a strong attraction alveoli = tiny folds of the lung epithelium to increase the surface area amphiphilic = attracted to both water and fat - containing hydrophobic and hydrophilic parts amylopectin molecule = a molecule of polysaccharide with glycosidic bonds between carbon 1 and 4, and branches formed by glycosidic bonds between 1 and 6. It is a constituent of starch amylose molecule = a molecule of polysaccharide with long straight chains of between 100 and 1000 alpha glucose molecules. It is a constituent of starch. Like maltose, it has glycosidic bonds between carbon 1 and 4 anatomical adaptations = structural features anatomy = a branch of science that concerns the studying of the structure of living organisms angina pectoris = a condition marked by severe pain in the chest, resulting from an inadequate blood supply, and therefore a lack of oxygen to the heart muscle that causes the coronary arteries to spasm anion = a negatively charged ion anomaly = result that does not fit the expected trend nor pattern aorta = the main artery of the body in mammals apoptosis = the death of cells which happens as a normal part of an organism's growth and development archaea = prokaryotic microorganisms of similar size to bacteria but have some differences of metabolism arteries = vessels that carry blood away from the heart arterioles = small blood vessels that distribute the blood from an artery to the capillaries artificial classification = a classification based on just one or a few characteristics artificial immunity = immunity that is achieved as a result of medical intervention artificial insemination = the medical procedure of injecting semen into the uterus of a female of the same species asymptomatic = having no symptoms atria = thin walled chambers of the heart that receive the blood from the veins and then pass it to the ventricles atrio-ventricular valves = valves between the atria and the ventricles, which ensure that the blood flows in the correct direction callose = a polysaccharide containing β 1-3 linkages and β 1-6 linkages between the glucose monomers that is important in the plant response to infection. carbaminohaemoglobin = the compound formed when carbon dioxide combines with haemoglobin. carbohydrates = organic polymers composed of the elements carbon, hydrogen and oxygen in the ratio Cx(H2O)y. Also known as saccharides or sugars. carbonic anhydrase = enzyme which catalyses the reversible reaction between carbon dioxide and water to form carbonic acid. cardiac cycle = the events of a single heartbeat, composed of diastole and systole. carrier proteins = membrane proteins that play a part in the transport of substances through a membrane. cartilage = strong, flexible connective tissue found in many areas of the bodies of humans and other animals catabolism (catabolic) = reactions of metabolism that break molecules down into smaller units. These reactions release energy. catalase = an enzyme that catalyses the breakdown of hydrogen peroxide. cell cycle = the highly ordered sequence of events that takes place in a cell, resulting in division of the nucleus and the formation of two genetically identical daughter cells cell signalling = a complex system of intercellular communication. cellulose = a polysaccharide formed from beta glucose molecules where alternate beta glucose molecules are turned upside down. It is unable to coil or form branches but makes hydrogen bonds with other cellulose molecules to produce strong and insoluble fibres. Major component of plant cell walls. cell wall = a strong but flexible layer that surrounds some cell-types. centrioles = component of the cytoskeleton of most eukaryotic cells, composed of microtubules. centromere = region at which two chromatids are held together channel proteins = membrane proteins that provide a hydrophilic channel through a membrane. checkpoints = control mechanisms of the cell cycle. chiasmata = sections of DNA, which became entangled during crossing over, break and rejoin during anaphase 1 of meiosis sometimes resulting in an exchange of DNA between bivalent chromosomes, forming recombinant chromatids and providing genetic variation. chloride shift = the movement of chloride ions into the red blood cells as hydrogen ions move out to maintain the electrochemical equilibrium. chloroplasts = organelles that are responsible for photosynthesis in plant cells. Contain chlorophyll pigments, which are the site of the light reactions of photosynthesis chromatids = two identical copies of DNA (a chromosome) held together at a centromere. chromatin = uncondensed DNA in a complex with histones. chromosomes = structures of condensed and coiled DNA in the form of chromatin. Chromosomes become visible under the light microscope when cells are preparing to divide. circulatory system = the transport system of an animal. clonal expansion = the mass proliferation of antibody-producing cells by clonal selection. clonal selection = the theory that exposure to a specific antigen selectively stimulates the proliferation of the cell with the appropriate antibody to form numerous clones of these specific antibody-forming cells (clonal expansion). closed circulatory system = a circulatory system where the blood is enclosed in blood vessels and does not come into direct contact with the cells of the body beyond the blood vessels. Clostridium difficile (C. difficile) = a species of Gram positive bacteria that is resistant to most antibiotics codon = a three-base sequence of DNA or RNA that codes for an amino acid. cofactors = non-protein components necessary for the effective functioning of an enzyme. cohesion-tension theory = the best current model explaining the movement of water through a plant during transpiration communicable diseases = diseases that can be passed from one organism to another, of the same or different species. community = all the populations of living organisms in a particular habitat. companion cells = the active cells found next to sieve tube elements that supply the phloem vessels with all of their metabolic needs competitive inhibitor = an inhibitor that competes with substrate to bind to active site on an enzyme. complementary base pairing = specific hydrogen bonding between nucleic acid bases. Adenine (A) binds to thymine (T) or uracil (U) and cytosine (C) binds to guanine (G). compound light microscope = a light microscope which uses two lenses to magnify an object; the objective lens, which is placed near to the specimen and an eyepiece lens, through which the specimen is viewed. condensation reaction = a reaction between two molecules resulting in the formation of a larger molecule and the release of a water molecule. The opposite reaction to a hydrolysis reaction continuous variation = a characteristic that can take any value within a range, e.g. height. contrast = staining or treating specific cell components so they are visible compared to untreated components convergent evolution = organisms evolve similarities because the organisms adapt to similar environments or other selection pressures. correlation coefficient = statistical test used to consider the relationship between two sets of data. countercurrent exchange system = a system for exchanging materials or heat when the two different components flow in opposite directions past each other counterstain = application of second stain with a contrasting colour to sample for microscopy crossing over = see chiasmata cytokines = cell-signalling molecules produced by mast cells in damaged tissues that attract phagocytes to the site of infection or inflammation. cytokinesis = cell division stage in the mitotic phase of the cell cycle that results in the production of two identical daughter cells. cytolysis = the bursting of an animal cell caused by increasing hydrostatic pressure as water enters by osmosis. cytoplasm = internal fluid of cells, composed of cytosol (water, salts and organic molecules), organelles and cytoskeleton. cytoskeleton = a network of fibres in the cytoplasm of a eukaryotic cell denatured (denaturation) = change in tertiary structure of a protein or enzyme, resulting in loss of normal function. deoxyribonucleic acid (DNA) = the molecule responsible for the storage of genetic information. diastole = the stage of the cardiac cycle in which the heart relaxes and the atria and then the ventricles fill with blood. dicotyledonous plants (dicots) = plants that produce seeds containing two cotyledons, which act as food stores for the developing embryo and form the first leaves when the seed germinates. differential staining = using specific stains to distinguish different types of cell. differentiation = the process of a cell becoming differentiated. Involves the selective expression of genes in a cell's genome. diploid = normal chromosome number; two chromosomes of each type − one inherited from each parent. disaccharide = a molecule comprising two monosaccharides, joined together by a glycosidic bond. discontinuous variation = a characteristic that can only result in certain discrete values, for example, blood type. divergent evolution = species diverge over time into two different species, resulting in a new species becoming less like the original one. DNA helicase = enzyme that catalyses the unwinding and separating of strands in DNA replication. DNA polymerase = enzyme that catalyses the formation of phosphodiester bonds between adjacent nucleotides in DNA replication. DNA replication = the semi-conservative process of the production of identical copies of DNA molecules. double circulatory system = a circulatory system where the blood travels twice through the heart for each complete circulation of the body. In the first circulation blood is pumped by the heart to the lungs. In the second circulation oxygenated blood is pumped by the heart to the brain and body to supply cells with oxygen. ectopic heartbeat = extra heartbeats that are out of the normal rhythm. elastic recoil = the ability to return to original shape and size following stretching. Particularly of the alveoli of the lungs and of the arteries. electrocardiogram (ECG) = a technique for measuring tiny changes in the electrical conductivity of the skin that result from the electrical activity of the heart. This produces a trace which can be used to analyse the health of the heart. electron microscopy = microscopy using a microscope that employs a beam of electrons to illuminate the specimen. As electrons have a much smaller wavelength than light they produce images with higher resolutions than light microscopes. emulsion test = laboratory test for lipids using ethanol; a white emulsion indicates the presence of a lipid. endocytosis = the bulk transport of materials into cells via invagination of the cell-surface membrane forming a vesicle. endosymbiosis = the widely-accepted theoretical process by which eukaryotic cells evolved from prokaryotic cells. end-product inhibition = the product of a reaction inhibits the enzyme required for the reaction. enzyme−product complex = complex formed as a result of an enzyme-catalysed reaction, when a substrate is converted to a product or products while bound to the active site of an enzyme. enzymes = biological catalysts that interact with substrate molecules to facilitate chemical reactions. Usually globular proteins. enzyme-substrate complex = complex formed when a substrate is bound to the active site of an enzyme. epidemic = when a communicable disease spreads rapidly to a lot of people at a local or national level. eukaryotes = multicellular eukaryotic organisms like animals, plants and fungi and single-celled protoctista. eukaryotic cells = cells with a nucleus and other membrane-bound organelles. ex situ conservation = conservation methods out of the natural habitat. exchange surfaces = surfaces over which materials are exchanged from one area to another. exocytosis = the bulk transport of materials out of cells. Vesicles containing the material fuse with the cell-surface membrane and the contents are released to the outside of the cell. exoskeleton = an external skeleton of some organisms, e.g. insects. expiratory reserve volume = the extra amount of air that can be forced out of the lungs over and above the normal exhalation (tidal volume). facilitated diffusion = diffusion across a plasma membrane through protein channels. fatty acids = long chain carboxylic acids used in the formation of triglycerides. fibrous proteins = long, insoluble, structural proteins. fluid-mosaic model = model of the structure of a cell membrane in which phospholipids within the phospholipid bilayer are free to move and proteins of various shapes and sizes are embedded in various positions. fossils = the remains or impression of a prehistoric plant or animal preserved in rock. founder effect = when a few individuals of a species colonise a new area, their offspring initially experience a loss in genetic variation, and rare alleles can become much more common in the population. Fungi = biological kingdom containing yeasts, moulds and mushrooms. gametes = haploid sex cells produced by meiosis in organisms that reproduce sexually. gaseous exchange system = the complex systems in which the respiratory gases oxygen and carbon dioxide are exchanged in an organism. gene = a section of DNA that contains the complete sequence of bases (codons) to code for a protein. gene flow = when alleles are transferred from one population to another by interbreeding. genetic bottleneck = when large numbers of a population die prior to reproducing, leading to reduced genetic biodiversity within the population. genetic code = the sequences of bases in DNA are the 'instructions' for the sequences of amino acids in the production of proteins. genetic variation = a variety of different combinations of alleles in a population. gills = the gaseous exchange organs of fish, comprised of gill plates, gill filaments and gill lamellae. globular proteins = spherical, water-soluble proteins. glucose = a monosaccharide with the chemical formula C6H12O6. One of the main products of photosynthesis in plants. glycerol = alcohol found in triglycerides. glycogen = a branched polysaccharide formed from alpha glucose molecules. A chemical energy store in animal cells. glycolipids = cell-surface membrane lipids with attached carbohydrate molecules of varying lengths and shapes. glycoproteins = extrinsic membrane proteins with attached carbohydrate molecules of varying lengths and shapes. glycosidic bond = a covalent bond between two monosaccharides. goblet cells = differentiated cells specialised to secrete mucus. Golgi apparatus = organelle in most eukaryotic cells formed from an interconnected network of flattened, membrane-enclosed sacs, or cisternae. Play a role in modifying and packaging proteins into vesicles. Gram negative bacteria = bacteria with cell walls that stain red with Gram stain. Gram positive bacteria = bacteria with cell walls that stain purple-blue with Gram stain. granum (plural grana) = a structure inside chloroplasts composed of a stack of several thylakoids. Contains chlorophyll pigments, where light reactions occur during photosynthesis. guard cells = cells that can open and close the stomatal pores, controlling gaseous exchange and water loss in plants. habitat = biodiversity the number of different habitats found within an area. haemoglobin = the red, oxygen-carrying pigment of red blood cells. haemoglobinic acid = the compound formed when haemoglobin accepts free hydrogen ions in its role as a buffer in the blood. haemolymph = the transport medium or 'blood' in insects haploid = half the normal chromosome number; one chromosome of each type. heterotrophic = organisms that acquire nutrients by the ingestion of other organisms. hexose monosaccharide = a monosaccharide composed of six carbons. histamines = chemicals produced by mast cells in damaged tissues that make the blood vessels dilate (causing redness and heat) and the blood vessel walls leaky (causing swelling and pain). histones = proteins that form a complex with DNA called chromatin. homologous chromosomes = matching pair of chromosomes, one inherited from each parent. homologous structure = a structure which appears superficially different but has the same underlying structure. hydrolysis = reaction the breakdown of a molecule into two smaller molecules requiring the addition of a water molecule. The opposite reaction to a condensation reaction. hydrophilic = the physical property of a molecule that is attracted to water. hydrophobic = the physical property of a molecule that is repelled by water. hydrophytes = plants with adaptations that enable them to survive in very wet habitats or submerged or at the surface of water. hydrostatic pressure = the pressure created by water in an enclosed system. immune response = a biological response that protects the body by recognising and responding to antigens and by destroying substances carrying non-self antigens. immunoglobulins = Y-shaped glycoproteins that form antibodies. in situ conservation = conservation methods within the natural habitat. independent assortment = the arrangement of each homologous chromosome pair (bivalent) in metaphase 1 and metaphase 2 of meiosis is independent of each other and results in genetic variation. induced-fit hypothesis = modified lock and key explanation for enzyme action; the active site of the enzyme is modified in shape by binding to the substrate. inflammation = biological response of vascular tissues to pathogens, damaged cells, or irritants, resulting in pain, heat, redness and swelling. inhibitor = a factor that prevents or reduces the rate of an enzyme-catalysed reaction. inspiratory reserve volume = the maximum volume of air that can be breathed in over and above a normal inhalation (tidal volume). insulin = a globular protein hormone involved in the regulation of blood glucose concentration. intercostal muscles = the muscles between the ribs that pull the ribs upwards during inhalation (internal intercostal muscles) and downwards during forced exhalation (external intercostal muscles) interleukins = a type of cytokine produced by T helper cells. interphase = growth period of the cell cycle, between cell divisions (mitotic phase). Consists of stages G1, S and G2. interspecific variation = the differences between organisms of different species. intraspecific variation = the differences between organisms of the same species. iodine test = chemical test for the presence of starch using a potassium iodide solution. A colour change to purple/black indicates a positive result. ion = an atom or molecule with an overall electric charge because the total number of electrons is not equal to the total number of protons. See anion and cation. ionic bond = a chemical bond that involves the donating of an electron from one atom to another, forming positive and negative ions held together by the attraction of the opposite charges. keystone species = species which are essential for maintaining biodiversity − they have a disproportionately large effect on their environment relative to their abundance. kingdom = the second biggest and broadest taxonomic group. lactose = a disaccharide made up of a galactose and glucose monosaccharide. laser scanning confocal microscope = a microscope that employs a beam of fluorescence and a pin-hole aperture to produce an image with a very high resolution. light microscope = an instrument that uses visible light and glass lenses to enable the user to see objects magnified many times. line transect = a line is marked along the ground and samples are taken at specified points. lipids = non-polar macromolecules containing the elements carbon, hydrogen and oxygen. Commonly known as fats (solid at room temperature) and oils (liquid at room temperature). lung surfactant = chemical mixture containing phospholipids and both hydrophilic and hydrophobic proteins, which coats the surfaces of the alveoli and prevents them collapsing after every breath. lymph = modified tissue fluid that is collected in the lymph system. lymphocytes = white blood cells that make up the specific immune system. lysosomes = specialised vesicles containin hydrolytic enzymes for the breakdown of waste materials within a cell. macromolecules = large complex molecules with a large molecular weight. maltose = two glucose molecules linked by a 1, 4 glycosidic bond. mass transport system = a transport system where substances are transported in a mass of fluid. meiosis = form of cell division where the nucleus divides twice (meiosis I and meiosis II) resulting in a halving of the chromosome number and producing four haploid cells from one diploid cell. membrane = a selectively-permeable barrier surrounding all cells and forming compartments within eukaryotic cells. membrane proteins = protein components of cell-surface membranes. meristematic tissue (meristems) = tissue found at regions of growth in plants. Contains stem cells. messenger (m)RNA = short strand of RNA produced by transcription from the DNA template strand. It has a base sequence complementary to the DNA from which it is transcribed, except it has uracil (U) in place of thymine (T). metaphase = second stage of mitosis when chromosomes line up at the metaphase plate. mitochondrial DNA = DNA present within the matrix of mitochondria. mitosis = nuclear division stage in the mitotic phase of the cell cycle. mitotic phase = period of cell division of the cell cycle. Consists of the stages mitosis and cytokinesis. monoculture = the cultivation of a single crop in a given area. monomers = individual molecules that make up a polymer. monosaccharide = a single sugar molecule. mRNA see messenger (m)RNA. MRSA (methicillin-resistant Staphylococcus aureus) = a mutated strain of the bacterium Staphylococcus aureus that is resistant to the antibiotic, methicillin. mucous membranes = membranous linings of body tracts that secrete a sticky mucus. multipotent = a stem cell that can only differentiate into a range of cell types within a certain type of tissue. mutation = a change in the genetic material which may affect the phenotype of the organism. myogenic = muscle which has its own intrinsic rhythm. natural active immunity = immunity which results from the response of the body to the invasion of a pathogen. natural passive immunity = the immunity given to an infant mammal by the mother through the placenta and the colostrum. natural selection = the process by which organisms best suited to their environment survive and reproduce, passing on their characteristics to their offspring through their genes. non-competitive inhibitor = an inhibitor that binds to an enzyme at an allosteric site. non-random sampling = an alternative sampling method to random sampling, where the sample is not chosen at random. It can be opportunistic, stratified or systematic. normal distribution curve = the bell-shaped curve that results from plotting continuous variation data on a graph. nucleic acids = large polymers formed from nucleotides. Contain the elements carbon, hydrogen, nitrogen , phosphorus, and oxygen. nucleotides = the monomers used to form nucleic acids. Made up of a pentose monosaccharide,a phosphate group and a nitrogenous base. oncotic pressure = the pressure created by the osmotic effect of the solutes in a solution open circulatory system = a circulatory system with a heart but few vessels to contain the transport medium. operculum = the bony flap covering the gills of bony fish. Part of the mechanism that maintains a constant flow of water over the gas exchange surfaces. opportunistic sampling = sampling using the organisms that are conveniently available. The weakest form of sampling as it may not be representative of the population. opsonins = chemicals that bind to pathogens and tag them so they are recognised more easily by phagocytes, e.g. antibodies. organelle = membrane-bound compartments with varying functions inside eukaryotic cells. osmosis = diffusion of water through a partially permeable membrane down a water potential gradient. A passive process. oxygen = dissociation curve graph showing the relationship between oxygen and haemoglobin at different partial pressures of oxygen. oxygenated blood = blood that has passed through the gas exchange organs (e.g. lungs) and is high in oxygen. pandemic = when a communicable disease spreads rapidly to a lot of people across a number of countries. partially permeable = membrane that allows some substances to cross but not others. passive transport = transport that is a passive process (does not require energy) and does not use energy from cellular respiration. pathogens = microorganisms that cause disease. penicillin = the first widely used, safe antibiotic, derived from a mould, Penicillium notatum. pentose monosaccharide = a monosaccharide composed of five carbons. peptide bond = bond formed between two amino acids. peptides = chains of two or more amino acid molecules. phagocytosis = process by which white blood cells called phagocytes recognise non-self cells, engulf them digest them within a vesicle called a phagolysosome. phagosome = the vesicle in which a pathogen or damaged cell is engulfed by a phagocyte. phloem = plant transport tissue that carries the products of photosynthesis (assimilates) to all cells of the plant. phosphodiester bonds = covalent bonds formed between the phosphate group of one nucleotide and the hydroxyl (OH) group of another. phospholipid bilayer = arrangement of phospholipids found in cell membranes; the hydrophilic phosphate heads form both the inner and outer surface of a membrane, sandwiching the fatty acid tails to form a hydrophobic core. phospholipids = modified triglycerides, where one fatty acid has been replaced with a phosphate group. phylogeny = the evolutionary relationships between organisms. pinocytosis = endocytosis of liquid materials. plasma = the main component of blood, a yellow fluid containing many dissolved substances and carrying the blood cells. plasma cells = B lymphocytes that produce about 2000 antibodies to a particular antigen every second and release them into the circulation. plasma membrane = all the membranes of cells, which have the same basic structure described by the fluid-mosaic model. pluripotent = a stem cell that can differentiate into any type of cell, but not form a whole organism. polymers = long-chain molecules composed of linked (bonded) multiple individual molecules (monomers) in a repeating pattern. polypeptide = chains of three or more amino acids. polysaccharide = a polymer made up of many sugar monomers (monosaccharides). primary immune response = the relatively slow production of a small number of the correct antibodies the first time a pathogen is encountered. prokaryotes = single-celled prokaryotic organisms from the kingdom Prokaryotae. prokaryotic cells = cells with no membrane-bound nucleus or organelles. prophase = first stage of mitosis when chromatin condenses to form visible chromosomes and the nuclear envelope breaks down. prosthetic group = non-protein component of a conjugated protein. proteases = enzymes that catalyse the breakdown of proteins and peptides into amino acids. Proteins = one or more polypeptides arranged as a complex macromolecule. Protista = biological kingdom containing unicellular eukaryotes. Purines = double-ringed, nitrogenous bases that form part of a nucleotide. Purkyne fibres = tissue that conducts the wave of excitation to the apex of the heart. Pyrimidines = single-ringed, nitrogenous bases that form part of a nucleotide. quaternary structure = the association of two or more protein subunits. random sampling = sampling where each individual in the population has an equal likelihood of selection. receptors = extrinsic glycoproteins that bind chemical signals, triggering a response by the cell. recombinant chromatids = chromatids with a combination of DNA from both homologous chromosomes, formed by crossing over and chiasmata in meiosis. reducing sugars = saccharides (sugars) that donate electrons resulting in the reduction (gain of electrons) of another molecule. reduction division = cell division resulting in the production of haploid cells from a diploid cell; meiosis. residual volume = the volume of air that is left in the lungs after forced exhalation. It cannot be measured directly resolution = the shortest distance between two objects that are still seen as separate objects. R-groups = variable groups on amino acids. ribonucleic acid (RNA) = molecules involved in the copying and transfer of genetic information from DNA. Polynucleotides consisting of a ribose sugar and one of four bases; uracil (U), cytosine (C), adenine (A), and guanine (G). ribose = the pentose monosaccharide present in RNA molecules. ribosomal (r)RNA = form of RNA that makes up the ribosome. RNA polymerase = enzyme that catalyses the formation of phosphodiester bonds between adjacent RNA nucleotides. root hair cells = cells found just behind the growing tip of a plant root that have long hairlike extensions that greatly increase the surface area available for the absorption of water and minerals from the soil. root pressure = the active pumping of minerals into the xylem by root cells that produces a movement of water into the xylem by osmosis. Saprophytic = organisms that acquire nutrients by absorption − mainly of decaying material. scanning electron microscopy = an electron microscope in which a beam of electrons is sent across the surface of a specimen and the reflected electrons are focused to produce a three dimensional image of the specimen surface. secondary immune response = the relatively fast production of very large quantities of the correct antibodies the second time a pathogen is encountered as a result of immunological memory − the second stage of a specific immune response. seed bank = a store of genetic material from plants in the form of seeds. selection pressure = factors that affect an organism's chance of survival or reproductive success. selective toxicity = the ability to interfere with the metabolism of a pathogen without affecting the cells of the host. selectively permeable = plasma membrane with protein channels that allows specific substances to cross only. semi-conservative replication = DNA replication results in one old strand and one new strand present in each daughter DNA molecule. sense strand = the strand of DNA that runs 5' to 3' and contains the genetic code for a protein. sieve plates = areas between the cells of the phloem where the walls become perforated giving many gaps and a sieve-like appearance that allows the phloem contents to flow through. sieve tube elements = the main cells of the phloem that have a greatly reduced living content and sieve plates between the cells. Simpson's Index of Diversity (D) = a measure of biodiversity that takes into account both species richness and species evenness. single circulatory system = a circulatory system where the blood flows through the heart and is pumped out to travel all around the body before returning to the heart. sinks (in plants) = regions of a plant that require assimilates to supply their metabolic needs, e.g. roots, fruits. sino-atrial node (SAN) = region of the heart that initiates a wave of excitation that triggers the contraction of the heart. smooth endoplasmic reticulum = endoplasmic reticulum lacking ribosomes; the site of lipid and carbohydrate synthesis, and storage. sources (in plants) = regions of a plant that produce assimilates (e.g. glucose) by photosynthesis or from storage materials, e.g. leaves, storage organs. Specialised = having particular structure to serve a specific function. Species = the smallest and most specific taxonomic group. a group of organisms that can freely interbreed to produce fertile offspring specific immunity = also known as active immunity or acquired immunity − the immune system 'remembers' an antigen after an initial response leading to an enhanced response to subsequent encounters. Spiracles = small openings along the thorax and abdomen of an insect that open and close to control the amount of air moving in and out of the gas exchange system and the level of water loss from the exchange surfaces. stage graticule = a slide with a scale in micrometres (μm) etched into it. Used to measure the size of a sample under a light microscope. stains (staining) = dyes used in microscopy sample preparation to increase contrast or identify specific components. Starch = a polysaccharide formed from alpha glucose molecules either joined to form amylose or amylopectin. stem cells = undifferentiated cells with the potential to differentiate into any of the specialised cell types of the organism. Stomata = pores in the surface of a leaf or stem that may be opened and closed by guard cells. That allow gaseous exchange stratified sampling = sampling where populations are divided into sub-groups (strata) based on a particular characteristic. A random sample is then taken from each of these strata proportional to its size. Stroma = fluid interior of chloroplasts. Student's t test = statistical test used to compare the means of data values of two populations. Substrate = a substance used, or acted on, by another process or substance. For example a reactant in an enzyme-catalysed reaction. Succession = the progressive replacement of one dominant type of species or community by another in an ecosystem, until a stable climax community is established Sucrose = a disaccharide made up of a fructose and glucose monosaccharides. sustainable development = economic development that meets the needs of people today, without limiting the ability of future generations to meet their needs. Symplast = the continuous cytoplasm of living plant cells connected through the plasmodesmata. symplast route = phloem loading through the cytoplasm of the cells via plasmodesmata by diffusion (passive). systematic sampling = different areas of a habitat are identified and sampled separately. Often carried out using a line or belt transect. Systole = the stage of the cardiac cycle in which the atria contract, followed by the ventricles, forcing blood out of the right side of the heart to the lungs and the left side of the heart to the body. T helper cells = T lymphocytes with CD4 receptors on their cell-surface membranes, which bind to antigens on antigen-presenting cells and produce interleukins, a type of cytokine. T killer cells = T lymphocytes that destroy pathogens carrying a specific antigen with perforin. T lymphocytes = lymphocytes which mature in the thymus gland and that both stimulate the B lymphocytes and directly kill pathogens. T memory cells = T lymphocytes that live a long time and are part of the immunological memory. T regulator cells = T lymphocytes that suppress and control the immune system, stopping the response once a pathogen has been destroyed and preventing an autoimmune response. Tachycardia = a fast heart rhythm of over 100 beats per minute at rest. taxonomic group = the hierarchical groups of classification - domain, kingdom, phylum, class, order, family, genus, species telophase = fourth stage of mitosis when chromosomes assemble at the poles and the nuclear envelope reforms. temperature coefficient (Q10) = a measure of how much the rate of a reaction increases with a 10 °C temperature increase. template strand = the antisense strand of DNA that acts as template during transcription so that the complementary RNA strand formed carries the same code for a protein as the DNA sense strand. tertiary structure = further folding of the secondary structure of proteins involving interactions between R-groups, to form hydrogen bonds, disulfide bridges, ionic bonds and hydrophobic interactions tidal volume = the volume of air which moves into and out of the lungs with each resting breath. Tissue = a collection of differentiated cells that have a specialised function or functions in an organism. tissue fluid = the solution surrounding the cells of multicellular animals. Tonoplast = membrane forming a vacuole in a plant cell. total lung capacity = the sum of the vital capacity and the residual volume. Totipotent = a stem cell that can differentiate into any type of cell and form a whole organism. Trachea = the main airway, supported by incomplete rings of cartilage, which carries warm moist air down from the nasal cavity into the chest. tracheal fluid = fluid found at the ends of the tracheoles in insects that helps control the surface area available for gas exchange and water loss. Transcription = the process of copying sections of DNA base sequence to produce smaller molecules of mRNA, which can be transported out of the nucleus via the nuclear pores to the site of protein synthesis. transfer (t)RNA = form of RNA that carries an amino acid specific to its anticodon to the correct position along mRNA during translation. Translation = the process by which the complementary code carried by mRNA is decoded by tRNA into a sequence of amino acids. This occurs at a ribosome. Translocation = the movement of organic solutes (assimilates) around a plant in the phloem. transmission electron microscopy (TEM) = an electron microscope in which a beam of electrons is transmitted through a specimen and focused to produce an image. transpiration = the loss of water vapour from the stems and leaves of a plant as a result of evaporation from cell surfaces inside the leaf and diffusion down a concentration gradient out through the stomata. (aerial parts of the plant) transpiration stream = the movement of water through a plant from the roots until it is lost by evaporation from the leaves. transport system = the system that transports required substances around the body of an organism. Triglyceride = a lipid composed of one glycerol molecule and three fatty acids. triplet code = the genetic code is a sequence of three nucleic acid bases, called a codon. Each codon codes for one amino acid. Turgor = the pressure exerted by the cell-surface membrane against the cell wall in a plant cell. Ultrastructure = the ultrastructure of a cell is those features which can be seen by using an electron microscope. (structure within a cell) Undifferentiated = an unspecialised cell originating from mitosis or meiosis. Vaccine = a safe form of an antigen, which is injected into the bloodstream to provide artificial active immunity against a pathogen bearing the antigen. (stimulates an immune response) Vacuoles = membranous sacs used to transport materials in the cell. vascular bundle = the vascular system of herbaceous dicots, made up of xylem and phloem tissue. vascular system = a system of transport vessels in animals or plants. Vector = a living or non-living factor that transmits a pathogen from one organism to another, e.g. malaria mosquito. Ventilation rate = is the total volume of air inhaled in one minute. Ventilation rate = tidal volume × breathing rate (per minute). vital capacity = volume of air that can be breathed in when the strongest possible exhalation is followed by the deepest possible intake of breath. Vmax = maximum initial velocity or rate of an enzyme-catalysed reaction. water potential (Ψ) = measure of the quantity of water compared to solutes, measured as the pressure created by the water molecules in kilopascals (kPa). The tendency of the water molecules to diffuse from one region to another. Xerophytes = plants with adaptations that enable them to survive in dry habitats or habitats where water is in short supply in the environment. Xylem = plant transport tissue that carries water and minerals from the roots to the other parts of the plant as a result of physical forces. Zygote = the initial diploid cell formed when two gametes are joined by means of sexual reproduction. Earliest stage of embryonic development. Xylem vessels = the tube which carry water up the plant water vapour potential gradient = a difference in the concentration of water vapour molecules inside the leaf compared to the outside waxy cuticle = these prevent water collecting on the cell surfaces. Since pathogens collect in the water and need water to survive, it's a passive defence wildlife reserves = areas set aside for the conservation of species or habitats vascular pathway = the route taken by water as is passes from cell to cell via the cytoplasm and vacuoles viable = capable of surviving or living successfully, especially under particular conditions venules = small blood vessels that collect blood from the capillaries and lead into the veins ventricles = the lower chambers in the heart, their walls create pressure to to pump the blood out of the heart and into the arteries venom = a harmful secretion injected into a victim by a venomous organism such as a snake or a spider ventilation = the refreshing of air in the lungs, so that there is a higher concentration of O2 than in the blood, and a lower C02 concentration veins = vessels that carry blood back to the heart variation = the presence of variety vasodilation = an increase in the diameter of the lumen of arterioles allowing and increased blood flow to specific region of the body vena cava = a large vein carrying deoxygenated blood into the heart validity = if an investigation provides the answer to the research question it is valid unsaturated fatty acid = there are double double carbon bonds, giving the hydrocarbon chain kinks urinary system = consists of two kidneys, ureters, the bladder, and the urethra. Each kidney consists of millions of nephrons, these systems deal with the removal of nitrogenous waste and with osmoregulation tendinous cords = cord like tendons in heart ventricles that connect the papillary muscles in the ventricle walls to the tricuspid/bicuspid valves in the heart to prevent the valves from turning inside out toxin = a substance that is poisonous to living cells/organisms tracheal system = a system of air filled tubes in insects transect = a line across a habitat transmission = passing a pathogen from an infected individual to an uninfected individual transverse section = a section cut crossways turgid = a swollen state of plant cells that have taken in water by osmosis and reached their maximum state of swelling. tylose = an outgrowth from parenchyma into the xylem vessels which can block the vessel systemic circulation = the part of the cardiovascular system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart systematic error = errors that may be inherent in the equipment and are repeated at every replicate. However if the percentage error is known , a calculation can be made to find the margin of error synthetic biology = the re-engineering of biology, this could be the production of new molecules that mimic natural processes or the use of natural molecules to produce new biological systems that do not exist in nature synthesis = making large molecules from small ones symbiosis = the relationship where two organisms coexist for their mutual benefit surface area to volume ratio = the surface area of an organism divided by its volume, expressed as a ratio succulent = a plant that stores water in its stem which becomes fleshy and swollen student's t-test = a test used to compare two means standard deviation = a measure of the spread around a mean squamous epithelial cells = flattened epithelial cells arranged in a layer spirometer = a device that can measure the movement of air into and out of the lungs spherocytosis = cells being more spherical in shape than they usually are species richness = a measure of how many different species are present species evenness = a measure of how evenly represented the species are soil depletion = the loss of soil fertility caused by removal of minerals by continuous cropping smooth muscle = involuntary muscle that contracts without the need for conscious thought sister chromatid = when a chromosome has replicated the resulting two identical chromatids produce are sister chromatids significant figures = the digits of the number that have a meaning and contribute to the numbers precisions septum = the walls that separated two chambers semilunar valves = valves that prevent blood re-entering that hear from the arteries selective breeding = the selection of specific traits in plants or animals through breeding programmes secondary structure = the coiling or folding of an amino acid chain, which arises often as a result of hydrogen bond formation between different parts of the chain. The main forms of secondary structure are the helix and the pleated sheet sampling techniques = techniques used to collect samples, for example random sampling, systematic and stratified sampling sarcomere = the smallest contractile unit of muscle sclerenchyma cells = plant cells that have lignified walls and are used to strengthen stems and leaf midribs secondary defences = defences which attack pathogens that have entered the body risk = the level of exposure to a hazard risk assessment = a way of managing risks by reducing exposure to hazards random error = statistical fluctuations in the measured data sure to the precision limitations of the measurement device regenerative medicine = stem cells may be used to populate a bioscaffold of an organ, and then directed to develop and grow into specific organs for transplanting reproductive system = a collection of organs that work together for the purpose of producing a new organism including gonads (ovaries and testes) and uterus respiration = a process in living organisms involving the release of energy from food; aerobic respiration occurs in the presence of oxygen and involves the release of carbon dioxide; anaerobic respiration occurs in the absence of oxygen and may involve the production of carbon dioxide and ethanol or the production of lactic acid, both aerobic and anaerobic respiration involve the oxidation of complex organic substances, such as glucose or fatty acids respiratory system = a biological system consisting of specific organs and structures used for the process of breathing gaseous exchange and respiration in an organism ribosome = a small organelle consisting of RNA and associated proteins found in large numbers in the cytoplasm of prokaryotic and eukaryotic cells and on the rough endoplasmic reticulum of eukaryotic cells. Each ribosome consists of two subunits. Amino acids are assembled into polypeptides at ribosomes, during a process called translation, where the ribosome moves along and reads instructions from a length of messenger RNA ring vaccination = used when a new case of disease is reported, All people who have been in contact with/live close to the patient are vaccinated palisade cells = closely packed photosynthetic cells within leaves partial pressure = the concentration of oxygen is measured by the relative pressure that it contributes to a mixture of gases. This is called that partial pressure of oxygen or pO2 parenchyma = a packing tissue in plants which fills spaces between other tissues. In roots parenchyma cells may store starch, In leaves some (called chlorenchyma) have chloroplasts and can photosynthesis. In aquatic plants aerenchyma tissue is parenchyma with air spaces to keep the plant buoyant passive immunity = immunity achieved when antibodies are passed to the individual though breast feeding or injection pepsin = an enzyme that digests protein in the stomach of mammals pericycle = a thin layer of meristem tissue between the endodermis and the phloem in plant roots peristalsis = the involuntary contraction and relaxation of the muscle layer of the intestine or another canal within the body, creating wave like movements which push the contents of the canal forward personalised medicine = the development of designer medicines for individuals phospholipid = molecule consisting of one glycerol, two fatty acids and one phosphate group photomicrograph = a photograph of an image seen using an optical microscope phylum = a major subdivision of the kingdom. A phylum contains all the groups of organisms that have the same body plan physiological adaptations = affect the way that processes work plasmodesmata = gaps in the cell wall containing cytoplasm that connects two cells plasmolysed = plant cell where the contents have shrunk due to loss of water by osmosis and the plasma membrane has separated from the cell wall plasmolysis = the process in which the protoplast of a plant cell shrinks as a result of water loss and the plasma membrane detaches from the cell wall platelets = small colorless disc shaped cell fragments without a nucleus, found in large numbers in blood and involved in clotting polar = where the change is not evenly distributed across the particle polymorphic gene locus = a locus that has more than two alleles polynucleotide = a large molecule consisting of many nucleotides polysaccharides = polymers of monosaccharides that are made of hundreds or thousands of monosaccharides monomers bonded together potometer = a device that can measure the rate of water uptake as a leafy stem transpires precision = the closeness of agreement between measured values obtained by repeated measurements primary defence = those that prevent pathogens entering the body primary structure = the sequence of amino acids found in a protein molecule product = molecule produced from substrate molecules by an enzyme catalyzed reaction pulmonary artery = the artery carrying blood from the right ventricle of the heart to the lungs for oxygenation pulmonary vein = the vein carrying oxygenated blood from the lungs to the left atrium order = taxonomic group, a subdivision of the class using additional information about the organism organ = collection of tissues working together to perform a function organ system = a number of organs working together to perform a specific function ossification = process of changing cartilage to bone by depositing calcium phosphate ostia = pores in the heart of an insect that allow blood from the body to enter the heart ovalocytosis = cells being more oval in shape that they usually are oxygen tension = measured in units of pressure (kPa). See partial pressure oxygen uptake = the volume of oxygen absorbed by the lungs in one minute oxyhaemoglobin = a molecule of haemoglobin with oxygen molecules loosely bound to it. When haemoglobin takes up oxygen, it becomes oxyhaemoglobin