1
Methods
The study's quantitative approaches were successful in providing enough answers to
the research questions posed. The goal of this study was to compare the risk of inactivated
flu vaccine to that of live attenuated influenza vaccination (LAIV) among children suffering
from asthma (Ray et al., 2017). The researchers observed asthma exacerbations in hospital or
emergency department settings after IIV and LAIV vaccines were issued among Kaiser
Permanente Northern California members of ages between the ages of 2 and 18 with a history
of asthma for a considerable time. They determined the relative risk of an exacerbation
occurring in a period of one to fourteen days against the reference period of twenty-nine to
forty-two days after vaccination for LAIV and IIV, respectively. The researchers then looked
at the odds ratio among kids who received LAIV and those who received IIV. The
researchers assessed the connection between vaccination and each outcome using a casecentered, risk-interval methodology. Therefore, these quantitative methods were appropriate
as they answered the research questions by drawing conclusions from analyzing the data
collected.
Literature Review
A literature review is relevant to the study, comprehensive, and analyzes studies that
were less than 5 years old since the research was conducted. This indicates that the writers
did an extensive search of the relevant literature. This shows that they took into account and
included the most recent findings to justify their study on asthma exacerbations and the
contrast between live attenuated and inactivated influenza vaccinations in children with
asthma. The relevance and importance of research cannot be determined without first
providing a thorough background in the relevant literature. The authors were able to identify
a knowledge gap and place their work in context by conducting this thorough literature
review. Therefore, the literature evaluation validated the need of doing this research.
2
References
Ray, G. T., Lewis, N., Goddard, K., Ross, P., Duffy, J., DeStefano, F., ... & Klein, N. P.
(2017). Asthma exacerbations among asthmatic children receiving live attenuated
versus inactivated influenza vaccines. Vaccine, 35(20), 2668-2675.