SKELETAL SYSTEM (BONE TISSUE) FUNCTIONS • Support • Protection • Assistance in movement • Mineral Homeostasis (storage and release) • Blood cell production • Triglyceride storage 4 TYPES OF CELLS VITAMINS • Vitamin A – stimulates activity of osteoblast • Vitamin C – synthesis of collagen (main protein) • Vitamin D – increase absorption of calcium from GIT into blood • Vitamin K and Vitamin B12 – synthesis of bone protein HORMONES FACTORS AFFECTING BONE GROWTH & BONE REMODELING • Minerals • Vitamins • Hormones • Exercise • Aging • EXERCISE • AGING MINERALS • Calcium and phosphorous HORMONES Human Growth Hormone (hGH) Anterior lobe of pituitary gland Insulinlike Growth Hormone (IGFs) Liver and bone tissues T3 and T4 Thyroid gland Insulin Pancreas Estrogen Ovaries Testosterone Testes Parathyroid Hormone (PTH) Parathyroid gland Calcitonin (CT) Thyroid gland THE AXIAL SKELETON & APPENDICULAR SKELETON AXIAL SKELETON