Title
Comparison of efficacy of ferrous sulfate and iron
polymaltose complex in the treatment of
childhood iron deficiency anemia
Research Gap

Comparison of efficacy of ferrous sulfate and iron
polymaltose complex in the treatment of
childhood iron deficiency anemia.
Question

What is the difference in efficacy between ferrous
sulfate and iron polymaltose complex for treating
childhood iron deficiency anemia?
Literature review

The World Health Organization (WHO) describes that the nutritional
anemia as basically a low level of hemoglobin due to insufficiency of
one or more essential nutrients.

IDA arises due to inadequate stores of iron in the body. Childhood IDA
is most common illness of developing countries, with an occurrence of
4-8% between 1-3 years of age.

Children under the age of 2 years are at higher risk because of
increased demand of nutritional iron and rapid growth.

Different iron preparations are obtainable. Ferrous sulfate and iron
polymaltose complex are most commonly used preparations. The
bioavailability, efficacy, cost and side effects of both therapies may
vary. Numerous investigations have done to found out the significant
effects of the therapies during childhood IDA (Santiago, 2012).
Hypothesis

It is hypothesized that iron polymaltose complex is
more effective and safe versus Ferrous sulfate in
the treatment of childhood IDA.
Objective

To compare the efficacy of Ferrous sulfate with
iron polymaltose complex in the treatment of
childhood iron deficiency anemia.
Study design
Inclusion Criteria
Exclusion criteria

IDA as per-operational
definition.

Anemia due to other
causative factors.

Children of both sex from 6
months-6 years of age will
be included.

Cardiovascular diseases.

Known hypersensitivity to
ferric and/or ferrous
preparations.

Systemic illnesses alike liver
diseases and renal failure.

History of recurrent blood
transfusions.

Parents refused for
consent.
Outcome

Outcome of the study will help to clear out picture
about the IDA and will mend our ways and help us to
adopt a single useful and practically proven therapy
which in the long run will help to prevent IDA and the
impending morbidity and mortality in children.
References

BOPCHE, A. V., DWIVEDI, R., MISHRA, R. & PATEL, G. 2009. Ferrous
sulfate versus iron polymaltose complex for treatment of iron
deficiency anemia in children. Indian pediatrics, 46.

GUPTA, P. M., PERRINE, C. G., MEI, Z. & SCANLON, K. S. 2016. Iron,
anemia, and iron deficiency anemia among young children in the
United States. Nutrients, 8, 330.

HARK, L., DEEN, D. & MORRISON, G. 2014. Medical nutrition and
disease: a case-based approach, John Wiley & Sons.

ORGANIZATION, W. H. 2009. Global health risks: mortality and burden
of disease attributable to selected major risks, World Health
Organization.
Thank you