NURS265: Module 6 Oral antidiabetic meds
ORAL ANTIDIABETIC MEDS
Med Class
How it works?
Will the med cause hypoglycemia?
Biguanide
Glucophage
(metformin)



Sulfonylureas
Glipizide,
glyburide, amaryl
Glinides
Repaglinide
(prandin)
Thiazolidinedione
Pioglitazone
(actos)
Alpha-glucosidase
inhibitor
Acarbose (precose)
 glucose production by liver
intestinal absorption of the
glucose
Improve insulin receptors
sensitivity

 Binds to receptors of beta-cells to
stimulate release of insulin
  secretion of glucagon

 Binds to receptors of beta-cells to
stimulate release of insulin
  secretion of glucagon

 insulin resistance by  insulin
receptors
 Stimulate peripheral glucose
uptake and storage
 Inhibit glucose production in liver

 Blocks enzyme that delays
absorption of glucose
 Reduces spike after meals

Contraindications
Adverse effects
Administer in regards to
meals