Name: ____________________________________ Date: _______________________________ Period: _______
https://youtu.be/QVCjdNxJreE
1. A multicellular organisms itself grows by making more cells—by making more cells by dividing—that’s
_______________________________________.
2. Mitosis and cytokinesis (splits the cytoplasm) allows for you to make ______________________________________.
3. Cancer is in part due to cells that divide ___________________. The cells are not regulated; they are uncontrolled.
4. Cancer cells may not be able to ________________________________ with other healthy, they may not carry out
__________________________________, they may not securely anchor themselves like other cells do which can
make them more likely to travel somewhere else.
5. Some cancer cells have the ability to _________________________ their own growth hormones that make blood
vessels divert over to those cancer cells and supply the cancer cells with ________________________, which is
taken away from healthy cells.
6. How do cells become cancerous?
7. What is a tumor?
8. How do doctors destroy cancer cells?
9. Chemotherapy targets cells that ___________________ frequently.
10. The cell cycle is often represented as a pie chart—they are either in one of the two different phrases: a phase called
__________________________ where the cells are growing, replicating their DNA, doing their cells functions—or
they are in _______________________________ which includes mitosis and the actual splitting of the cytoplasm—
cytokinesis.
11. Where do cells spend most of their time?
12. From the video, what type of cells do mitosis frequently and sometimes cancer drugs target these cells too?
Name: ____________________________________ Date: _______________________________ Period: _______
13. What is a mutation?
14. Along the cell cycle, there are ________________________ to check that the cell is growing well; replicating its DNA
correctly; and functioning correctly.
15. G1, S, and G2 phase are all apart of ___________________. Then we have M phases where ________________ will
happen.
16. Complete the chart:
Phase
G1
Function
DNA is replicated
the cell grows some more in preparation for mitosis
17. What are the phases of mitosis?
18. In metaphase, the chromosomes (which are made up of DNA) are lined up in the ___________________ correctly—
that they are all attached to the spindle correctly.
19. What happens if the cell does not met the requirements of the checkpoint?
20. What is doing the regulating of the cycle?
21. What are the two proteins involved in positive regulation?
22. Different types of cyclin rise and fall throughout the cell cycle, and the rising and falling is based on a variety of
_____________________ to determine when the cell should move onto the next cell cycle phase.
23. Name a protein that is a negative regulator.
24. What is a G0 (G-Zero) phase?
25. What type of cells can be found in the G0 (G-Zero) phase typically?
Name: ____________________________________ Date: _______________________________ Period: _______
https://youtu.be/QVCjdNxJreE
KEY
1. A multicellular organisms itself grows by making more cells—by making more cells by dividing—that’s cell
reproduction.
2. Mitosis and Cytokinesis (splits the cytoplasm) allows for you to make new body cells.
3. Cancer is in part due to cells that divide too frequently. The cells are not regulated; they are uncontrolled.
4. Cancer cells may not be able to communicate with other healthy, they may not carry out normal cells functions,
they may not securely anchor themselves like other cells do which can make them more likely to travel somewhere
else.
5. Some cancer cells have the ability to secrete their own growth hormones that make blood vessels divert over to
those cancer cells and supply the cancer cells with nutrients, which is taken away from healthy cells.
6. How do cells become cancerous?
genetic links, exposure to toxins, radiation, or excessive exposure to UV light are risk factors
7. What is a tumor?
Uncontrolled growth of cancer cells
8. How do doctors destroy cancer cells?
radiation or medication such as chemotherapy
9. Chemotherapy targets cells that divide frequently.
10. The cell cycle is often represented as a pie chart—they are either in one of the two different phrases: a phase called
interphase where the cells are growing, replicating their DNA, doing their cells functions—or they are in M phase
which includes mitosis and the actual splitting of the cytoplasm—cytokinesis.
11. Where do cells spend most of their time?
Interphase
12. From the video, what type of cells do mitosis frequently and sometimes cancer drugs target these cells too?
Hair follicle cells
13. What is a mutation?
An error in a cell
14. Along the cell cycle, there are check points to check that the cell is growing well; replicating its DNA correctly; and
functioning correctly.
15. G1, S, and G2 phase are all apart of interphase. Then we have M phases where mitosis will happen.
Name: ____________________________________ Date: _______________________________ Period: _______
16. Complete the chart.
Phase
G1
S
G2
Function
the cell individually itself grows
DNA is replicated
the cell grows some more in preparation for mitosis
17. What are the phases of mitosis?
prophase, metaphase, anaphase, and telophase
18. In metaphase, the chromosomes (which are made up of DNA) are lined up in the middle correctly—that they are all
attached to the spindle correctly.
19. What happens if the cell does not met the requirements of the checkpoint?
if it can be fixed = cell limbo; if it cannot be fixed = apoptosis (the cell self-destructs)
20. What is doing the regulating of the cycle?
Proteins—positive regulators & negative regulators.
21. What are the two proteins involved in positive regulation?
Cdk (protein) and Cyclin (enzyme)
22. Different types of cyclin rise and fall throughout the cell cycle, and the rising and falling is based on a variety of
signals to determine when the cell should move onto the next cell cycle phase.
23. Name a protein that is a negative regulator.
p53
24. What is a G0 (G-Zero) phase?
A resting phase—cells are not preparing to divide, not enough resources,
25. What type of cells can be found in the G0 (G-Zero) phase typically?
Neurons from the brain or spine—hence why recovery from a brain or spinal injury can be challenging