MULUNGUSHI UNIVERSITY
SCHOOL OF SCIENCE, ENGINEERING AND TECHNOLOGY
(SSET)
DEPARTMENT OF SCIENCE, MATHEMATICS AND STATISTICS
BIO 112@2021
TUTORIAL SHEET 2-DNA REPLICATION, TRANSCRIPTION AND TRANSLATION
1. Explain the different models of DNA replication.
2. Differentiate conservativeness and semi-conservativeness of DNA.
3. Describe the various stages of DNA replication and the enzymes involved (plus the roles
played by each enzyme mentioned).
4. What is the difference between the genetic code and a codon?
5. List the enzymes involved in prokaryotic DNA synthesis and the role of each one of them.
6. What is a gene?
7. What is the central dogma of molecular biology?
8. Explain the features of the genetic code.
9. Explain the role of stop and start codons and the amino acids they code for.
10. Why is DNA referred to as the blue print of protein synthesis?
11. Discuss posttranscriptional modification in detail, and the significance of the modifications.
12. Explain the role of each type RNA and how they differ one from the other?
13. Differentiate between introns and exons and state the different types of RNA (explain how
they differ from each other).
14. Discuss the processes involved in post translational modification of RNA.
15. Define the word mutation and explain the effects of mutations.
16. Give 2 examples of a ‘gain of function mutation’ and ‘loss of function mutation’.