KWAME NKRUMAH UNIVEERSITY OF SCIECNCE AND TECHNOLOGY FACULTY OF PHARMACY AND PHARMACEUTICAL SCIENCES. DEPARTMENT OF PHARMACY PRACTICE Name: Kristabel Abotsi Index number: 1572117 QUESTION • What are the types of internal validity? • What are the threats to internal and external validity and how can they be resolved? ANSWERS Internal validity is the degree of confidence that the causal relationship you are testing is not influenced by other factors or variables. There are several types of internal validity that can impact the conclusions drawn from a research study and they include: • Content validity: determines whether the experiment is best suited for your research methodology. • Face validity: shows if the research results accurately represent the research’s aims. • Criterion validity examines whether the result of one research matches the outcome of another that uses the same details • Construct validity: determines whether your experiment yields the results you expected. Some threats to international validity include 1. History: History refers to events that occur during the course of a study that are not related to the independent variable but may influence the dependent variable. For example, if a study investigating the effect of a new educational program on student learning coincides with a major teacher strike, the strike may confound the results of the study. 2. Maturation: Maturation refers to changes that occur naturally in participants over time that may influence the dependent variable. For example, in a study investigating the effect of a new nutrition program on weight loss, participants' weight loss may be influenced by natural changes in their metabolism or body composition over time. 3. Testing: Testing refers to the potential for participants to improve their performance on a measure as a result of having taken the test before. For example, if a study uses a pretest/post-test design, participants may improve their performance on the post-test simply because they are more familiar with the test format. 4. Instrumentation: Instrumentation refers to changes in the measurement instrument or procedure that may impact the results of a study. For example, if a study measuring anxiety levels uses two different types of scales at different time points, the results may be confounded by differences in the scales rather than changes in anxiety levels. 5. Selection bias: Selection bias occurs when the groups being compared are not equivalent at the outset of a study. For example, if a study comparing the effectiveness of two different interventions for depression assigns participants to groups based on their availability or willingness to participate, the groups may differ in important ways that impact the results of the study. External validity is the extent to which you can generalize the findings of a study to other situations, people, settings, and measures. There are two main types of external validity: population validity and ecological validity. • Population Validity Population validity refers to whether you can reasonably generalize the findings from your sample to a larger group of people (the population). The selection of the population and how closely the study sample reflects that population are key factors in population validity. Methods of nonprobability sampling are frequently utilized for convenience. Using this kind of sampling, the results can only be generalized to populati ons having similar characteristics to the sample. • Ecological Validity Ecological validity refers to whether you can reasonably generalize the findings of a study to other situations and settings in the ‘real world’. There are also several threats to external validity, including: 1. Experimental setting: The setting in which the study is conducted may be artificial and not representative of the real-world conditions in which the variables of interest operate. 2. Reactivity: Participants may behave differently in a research setting than they would in their normal environment, which can limit the generalizability of the findings. 3. Harthwone Effect: The tendency for participants to change their behaviors simply because they know they are being studied. For example The participants actively avoid anxiety-inducing situations for the period of the study because they are conscious of their participation in the research. 4. Time-related factors: The effects of an intervention or treatment may change over time, which can limit the generalizability of the findings to other times or contexts. 5. Measurement bias: The measurement tools used in a study may not be appropriate or accurate for the population of interest, which can limit the generalizability of the findings. 6. Observer Bias: The characteristics or behaviors of the experimenter(s) unintentionally influence the outcomes, leading to bias and other demand characteristics. To address these threats to internal and external validity, researchers can take several steps: 1. Control for extraneous variables: Careful control of extraneous variables through random assignment and other control procedures can increase internal validity. 2. Use appropriate research design: Selecting a research design that minimizes or eliminates the effects of confounding variables, such as using a randomized controlled trial, can increase internal validity. 3. Use representative samples: Sampling from a population that is representative of the target population can increase external validity. 4. Use multiple settings: Conducting the study in multiple settings can help to increase external validity by ensuring that the results are not specific to one particular environment. 5. Use naturalistic settings: Using naturalistic settings that are similar to the real-world environment in which the variables operate can increase external validity. 6. Replications: These are able to counter almost all threats by enhancing generalizability to other settings, populations and conditions. 7. Probability sampling: This counters selection bias by making sure everyone in a population has an equal chance of being selected for a study sample. 8. Recalibration or reprocessing also counters selection bias using algorithms to correct weighting of factors (e.g., age) within study samples. REFERENCES • Campbell, D. T., & Stanley, J. C. (1963). Experimental and quasi-experimental designs for research. Houghton Mifflin. • Shadish, W. R., Cook, T. D., & Campbell, D. T. (2002). Experimental and quasiexperimental designs for generalized causal inference. Houghton Mifflin. • Trochim, W. M. (2006). The research methods knowledge base. Atomic Dog. • Cook, T. D., & Campbell, D. T. (1979). Quasi-experimentation: Design and analysis issues for field settings. Rand McNally