What is the difference between meiosis I and meiosis II? Meiosis is a specialized type of cellular division that occurs in sexually reproducing organisms, resulting in the production of gametes such as eggs and sperm. There are two phases of meiosis: meiosis I and meiosis II. Meiosis I and meiosis II are similar in some ways, but they have some important differences. One of the biggest differences between meiosis I and meiosis II is the way the chromosomes align and separate. During meiosis I, homologous chromosomes pair up and exchange genetic information in a process called crossing over. This genetic recombination creates new combinations of traits in the resulting gametes. The homologous chromosomes then separate and move to opposite ends of the cell, forming two new cells. In meiosis II, the two cells produced in meiosis I divide again, this time separating the sister chromatids (identical copies of each chromosome) into four new cells. This process is similar to mitosis, but there are some important differences, such as the fact that there is no replication of DNA between meiosis I and meiosis II. Another important difference between meiosis I and meiosis II is the number of chromosomes in each resulting cell. At the end of meiosis I, each cell has half the number of chromosomes as the original parent cell, while at the end of meiosis II, each cell has a complete set of chromosomes, but all of the chromosomes are made up of only one chromatid (rather than two). In summary, meiosis I and meiosis II are both important types of cellular division in sexually reproducing organisms. Meiosis I involves the separation of homologous chromosomes and genetic recombination, while meiosis II involves the separation of sister chromatids to produce four new cells with a complete set of chromosomes. References: - Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2002). Molecular biology of the cell (4th ed.). Garland Science. - Griffiths, A. J., Wessler, S. R., Carroll, S. B., & Doebley, J. (2015). Introduction to genetic analysis (11th ed.). W. H. Freeman.