1. Glycolytic pathway regulation involves
A. allosteric stimulation by ADP
B. allosteric inhibition by ATP
C. feedback, or product, inhibition by ATP
D. all of the above
2. During catabolism, only about 40% of the energy available from oxidizing glucose is used to synthesize ATP. Remaining 60%
A. is lost as heat
B. is used to reduce NADP
C. remains in the products of metabolism
D. is stored as fat.
3. Why does the glycolytic pathway continue in the direction of glucose catabolism?
A. There are essentially three irreversible reactions that act as the driving force for the pathway
B. High levels of ATP keep the pathway going in a forward direction
C. The enzymes of glycolysis only function in one direction
D. Glycolysis occurs in either direction
4. The released energy obtained by oxidation of glucose is stored as
A. a concentration gradient across a membrane
B. ADP
C. ATP
D. NAD+
5. A kinase is an enzyme that
A. removes phosphate groups of substrates
B. uses ATP to add a phosphate group to the substrate
C. uses NADH to change the oxidation state of the substrate
D. removes water from a double bond
6. For every one molecule of sugar glucose which is oxidized __________ molecule of pyruvic acid are produced.
A. 1
B. 2
C. 3
D. 4
7. In the glycogen synthase reaction, the precursor to glycogen is
A. glucose-6-P
B. UTP-glucose
C. UDP-glucose
D. glucose-1-P
8. The active form of glycogen phosphorylase is phosphorylated, while the dephosphorylation of which active form occurs?
A. Glycogen synthase
B. Glycogen semisynthase
C. Glycogen hydrolase
D. Glycogen dehydrogenase
9. The enzymes of glycolysis in a eukaryotic cell are located in the
A. intermembrane space
B. plasma membrane
C. cytosol
D. mitochondrial matrix
10. When concentration of the reactants is higher than the equilibrium concentration then
A. the gibbs free energy will be positive
B. the gibbs free energy will be negative
C. more products will be formed
D. both (b) and (c)
11. Which of the following is not true of glycolysis?
A. ADP is phosphorylated to ATP via substrate level phosphorylation
B. The pathway does not require oxygen
C. The pathway oxidizes two moles of NADH to NAD+ for each mole of glucose that enters
D. The pathway requires two moles of ATP to get started catabo-lizing each mole of glucose
12. In glycolysis, ATP is formed by the transfer of a high-energy phosphate from 1,3-bisphosphoglycerate to ADR No such high-energy phosphate
donor has ever been isolated in mitochondria because
A. the techniques for isolating the phosphate donor are not refined enough
B. no such phosphate donor exists
C. the high-energy phosphate donor is very short-lived and difficult to isolate
D. None of the above
13. ATP is from which general category of molecules?
A. Polysaccharides
B. Proteins
C. Nucleotides
D. Amino acids
14. The glycolytic pathway (glucose 2 pyruvate) is found
A. in all living organisms
B. primarily in animals excluding particles
C. only in eukaryotes
D. only in yeast