Radiology of Hepatobiliary system and Pancreas Dr. K. M. Das, MD Associate Professor, Radiology CMHS Radiology of Hepatobiliary system and Pancreas Ultrasonography Computed tomography MRI: Magnetic resonance Imaging Radiology of Hepatobiliary system and Pancreas- Goal Detection of lesion Extent of disease Etiology Patient management: Further studies, Biopsy, Surgery Radiology of Hepatobiliary system and Pancreas Liver Gall bladder Pancreas Common Hepatic lesions Hepatic cysts Hemangiomas Focal Nodular hyperplasia Hepatic adenoma Hepatoma Metastases Hepatic cysts Hepatic cyst Multiple cysts Polycystic Kidney Disease D/D Hepatic cyst: Liver abscess Early Presentation Late Presentation Ovarian cancer : Metastases Hepatic Cyst Simple cyst Malignant cyst CT angiography Hepatic Cyst Simple cyst Malignant cyst Common Hepatic lesions Hepatic cysts Hemangiomas Focal Nodular hyperplasia Hepatic adenoma Hepatoma Metastases Hemangioma of Liver Hemangioma of Liver Hemangioma of Liver Common Hepatic lesions Hepatic cysts Hemangiomas Focal Nodular hyperplasia Hepatic adenoma Hepatoma Metastases Focal Nodular hyperplasia Second most common tumor of Liver Most common in reproductive-aged women Hyperplastic hepatocytes/ Hamartoma No bleed / Malignant transformation the liver Focal Nodular hyperplasia (FNH) Focal Nodular hyperplasia (FNH) Arterial Venous Delayed Abnormal vessel Common Hepatic lesions Hepatic cysts Hemangiomas Focal Nodular hyperplasia Hepatic adenoma Hepatoma Metastases Hepatic adenoma: facts More common in woman Contraceptive Contain Fat and Glycogen Known to bleed Transform to Hepatoma Hepatic adenoma: facts- CT findings Hepatic adenoma: facts- CT findings Hepatic adenoma: facts- CT findings Bleed Hepatic adenoma: facts- CT findings Very difficult to differentiate a hepatic adenoma from Hepatoma Hepatoma (HCC) : Facts Most common primary hepatic malignancy Incidence : 2.4 per 100,000 per year Hepatoma is the leading causes of death in patients with Cirrhosis. Hepatoma : HCC-Hepatocellular carcinoma. Hepatoma : HCC-Hepatocellular carcinoma. Arterial Phase Venous Phase Hepatoma : Facts. 3D Map Gall bladder Gall bladder : Ultrasonography Acoustic shadowing Acute cholecystitis Gall bladder : Ultrasonography Mirizzi syndrome is a rare complication of gallstone disease in which a gallstone becomes impacted in the cystic duct or neck of the gallbladder causing compression of the common bile duct (CBD) Mirizzi syndrome Gall Bladder perforation Gall Bladder perforation- Gall stone ileus. Gall Bladder Cancer Most aggressive cancer. Surgical resection: 50% survive 5 years. Non Surgical: 5% survive 5 years. Gall Bladder Cancer Gall Bladder Cancer Gall Bladder Cancer: Invading liver Pancreas Acute Pancreatitis: CT Best screening modality: CT Disease severity and the outcome prediction Identify complications and Guide interventions Acute Pancreatitis: CT Normal Pancreas Adenocarcinoma Pancreas 4th Leading cause of Cancer mortality Poor prognosis with <5% survival at 5 years <20% of patients are candidates for curative surgery Adenocarcinoma of Pancreas: CT Adenocarcinoma Pancreas : CT MRI : Indication Equivocal diagnosis Elastography Cirrhosis of Liver Chemical shift Imaging Biliary duct pathology Endoscopic retrograde cholangiopancreatography (ERCP) MRCP : Magnetic resonance cholaniopancreatography MRCP : Magnetic resonance cholaniopancreatography Primary sclerosing cholangitis MRCP ERCP MR: Chemical shift imaging In Phase Out of Phase MR Elastography (MRE) stiffness value of 2.1 kPa stiffness value of 2.1 kPa Normal < 2.9 kPa stiffness value of 4.8 kPa stiffness value of 8 kPa Summary 1 Increased lesion detection does not necessarily mean a more accurate study. In fact, most mm size lesions are benign cyst or hemangiomas Summary 2 Lesion detection is not enough Creating a long differential diagnosis is not the key Creating a decisive diagnosis is the key