Tolerable Upper Intake Levels (ULs) ,. I• I C / / .‘ r /—‘ •, ..., ,/ •‘ ,1’ , ., ; .... / % / ,1’ , . /. ., . .! .,.%;/•%/ 3 .‘\ ‘‘ ..,. ,/ •. /_ / Infants 0—6 mc NDd 1,000 ND 0.7 ND 40 ND ND ND ND ND 6—l2mo ND 1,500 ND 0.9 ND 40 ND ND ND ND ND 3 2,500 1,000 1.3 200 40 65 2 300 0.2 110 3 600 0.3 45 60 ND ND 4 3 90 ND 3 150 ND ND ND ND ND 7 12 1.5 1.9 2,3 2.9 ND ND 1.8 1.8 1.8 1.8 23 34 40 40 40 40 2.2 2.3 2.3 2.3 2.3 2.3 3.4 3.6 3.6 3.6 3.6 3.6 ND ND 1.8 1.8 1.8 1.8 23 34 40 40 40 40 2.2 2.3 2.3 2.3 2.3 2.3 3.4 3.6 3.6 3.6 3.6 3.6 ND ND 34 40 2.3 2.3 3.6 3.6 2.3 2.3 3.6 3.6 5 Children 1—3 y 4—8y 6, 2,500 3,000 2.2 300 40 Males 9—13y l4—JBy 19—30y 31—50y 51—70y >70y 11 3,000 5,000 10 600 40 350 6 1,100 0.6 17 20 20 20 20 3,000 2,500 2,500 2,000 2,000 8,000 10,000 10,000 10,000 10,000 10 10 10 10 10 900 1,100 1,100 1,100 1,100 45 45 45 45 45 350 350 350 350 350 9 11 11 11 11 1,700 2,000 2,000 2,000 2,000 1.0 1.0 1.0 1.0 1.0 4 4 4 4 4 3 280 400 400 400 400 400 Females 9—l3y 14—18y 19—30y 3l—50y 51—7Oy >70y 11 17 20 20 20 20 3,000 3,000 2,500 2,500 2,000 2,000 5,000 8,000 10,000 10,000 10,000 10,000 10 10 10 10 10 10 600 900 1,100 1,100 1,100 1,100 40 45 45 45 45 45 350 350 350 350 350 350 6 9 11 11 11 11 1,100 1,700 2,000 2,000 2,000 2,000 0.6 1.0 1.0 1.0 1.0 1.0 4 4 4 4 4 3 280 400 400 400 400 400 Pregnancy 14—l8y 19—SOy 17 20 3,000 8,000 2,500 10,000 10 10 900 1,100 45 45 350 350 9 11 1,700 2,000 1.0 1.0 3.5 3.5 400 400 Lactation 14—18y 19—SOy 17 20 3,000 8,000 2,500 10,000 10 10 900 1,100 45 45 350 350 Note: A Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effect5 to almost all individuals in the general population. Unless otherwise specified, the UL represents total intake from food, water, and supplements. Due to a lack of suitable data, ULs could not be established for vitamin K, thiamin, riboflavin, vitamin B, pantothenic acid, biotin, and catotenoids. In the absence of a UL extra caution may be warranted in consuming levels above recommended intakes. Members of the general population should be advi5ed not to routinely exceed the UL The UL is not meant to apply to individuals who are treated with the nutrient under medical supervision or to individuals with predisposing conditions that modify their sensitivity to the nutrient. 9 11 1,700 2,000 1.0 1.0 4 4 400 400. I ND ND 34 40 ND = Not determinable due to lack of data of adverse effects in this age group and concern with regard to lack of ability to handle excess amounts. Source of intake 5hould be from food only to prevent high levels of intake. The ULs for magnesium represent intake from a pharmacological agent only and do not include intake from food and water. Although vanadium in food has not been shown to cause adverse effects in humans, there is no justification for adding vanadium to food, and vanadium supplements should be used with caution. The UL is based on adverse effects in laboratory animals, and this data could be used to set a UL for adults but not children and adolescents. Dato from: Reprinted with permission from the Dietary Reference Intakes series. Copyright 1997, 1998, 2000,2001, 2005,2011 by the National Academies of Sciences, courtesy of the National Academies Press, Wa5hington, D.C. These reports may be accessed via www.nap.edu. 1 I Tolerable Upper Intake Levels (ULs) Vitamins 1 / ., /. . , 6-l2mo Children 1—3y _____ / . .. , * ,,. S’\’’ Sr4 -- ‘‘‘ .,, ‘ — %•/ / “a ‘ 4% %J /t /..‘S çc infants 0-6 ma / ‘%) ‘,%r 600 NDU 25 ND ND ND ND 600 ND 38 ND ND ND ND 400 650 63 75 200 300 10 15 30 40 400 1.0 1,0 600 900 — 300 ND ND Males 9—13y 1,700 1,200 100 600 20 60 600 2.0 14—18y 2,800 1,800 100 800 30 80 800 3.0 l9—30y 31—SOy 5l—7Oy >7Oy 3,000 3,000 3,000 3,000 2,000 2,000 2,000 2,000 100 100 100 100 1,000 1,000 1,000 1,000 35 35 35 35 100 1,000 3.5 100 1,000 3.5 100 1,000 3.5 100 1,000 3.5 Females 9—l3y 14—18y l9—3Oy 3l—5Oy S1—7Oy >7Oy 1,700 2,800 3,000 3,000 3,000 3,000 1,200 1,800 2,000 2,000 2,000 2,000 100 100 100 100 100 100 600 800 1,000 1,000 1,000 1,000 20 30 35 35 35 35 60 80 100 100 100 100 600 800 1,000 1,000 1,000 1,000 2.0 3.0 3.5 3.5 3.5 3.5 Pregnancy l4—l8y 19—50y 2,800 3,000 1,800 2,000 100 100 800 1,000 30 35 80 100 800 1,000 3.0 3.5 Lactation l4—l8y 19—SOy 2,800 3,000 1,800 2,000 100 100 800 1,000 30 35 80 800 100 1,000 3.0 3.5 Note: A Tolerable Upper Intake Level (UL) is the highest level of daily nutrient intake that is likely to pose no risk of adverse health effects to almost all individuals in the general population. Unless otherwise specified, the UL represents total intake from food, water, and sup plements. Due to a lack of suitable data, UL5 could not be established for vitamin K, thiamin, riboflavin, vitamin B12, pantothenic acid, biotin, and carotenoids. In the absence of a UL, extra caution may be war ranted in consuming levels above recommended intakes. Members of the general population should be advised not to routinely exceed the UL. The UL is not meant to apply to individuals who are treated with the nutrient under medical supervision or to individuals with predisposing conditions that modify their sensitivity to the nutrient. a As preformed vitamin A only. As ci-tocopherol; applies to any form of supplemental ci-tocopherol. cThe ULs for vitamin E, niacin, and folate apply to syn thetic forms obtained from supplements, fortified foods, or a combination of the two. ND = Not determinable due to lack of data of adverse effects in this age group and concern with regard to lack of ability to handle excess amounts. Source of intake should be from food only to prevent high levels of intake. Data from: DIETARY REFERENCE INTAKES series, National Academies Press. Copyright ©1997, 1998, 2000, 2001, and 2011, by the National Academy of Sciences. These re ports may be accessed via www.nap.edu. Courtesy of the National Academies Press, Washington, DC. Reprinted with permission. Dietary Reference Intakes: RDA,AI* Infants 0—6mo 6—l2mo 0.01* 0.5* 110’ 130* 0.27’ 17 340 440 0.7* 90 90 7 10 80 130 700 890 900 900 900 900 2’ 120 150 150 750 750 150 8 11 8 8 8 8 240 470 400 420 420 420 8 75 78 18 8 8 240 360 370 320 320 320 0.2* 200’ 260’ 5.5’ 220* 700 7,000 11’ 1,300 1,300 1,000 7,000 1,000 1,200 25’ 1,300 1,300 7,000 1,000 7,200 1,200 21’ 7,300 1,000 7,000 29* 1,300 1,000 7,000 44’ 200* I 30’ 75’ 0.4’ 0.7’ 0.12’ 0.37’ Q* 0.57* 3 5 3.0’ 1.0’ 1.2’ 1.5’ 1.9’ 40 55 55 55 55 55 8 71 11 11 11 71 4.5’ 4,7* 47* 1.5’ 1.5* 2,3* 4.7’ 4.7’ 4.7’ 1.5’ 1.5’ 1.3’ 1.2’ 1,250 1,250 700 700 700 700 40 55 55 55 55 55 8 9 8 8 6 8 4,5* 1.5* 4.7 4.7’ 4.7’ 4.7’ 4.7’ 1.5’ 1.5* 1.5’ 1.3’ 1.2’ 2.3’ 2.0* 47* 1.5’ 1.5’ 1.5’ 2.3’ 2.3’ 2.3’ 1.5’ 1.5’ 1.5, 2.3’ 2.3’ 2.3* 2* 0.003* 0.6* 2’ 3* 275* 15’ 20* 3 1.2’ 17 22 460 500 20 30 34 43 45 45 45 45 7,250 7,250 700 700 700 700 1.6’ 1.8’ 1.8’ 1.8’ 1.8’ 34 43 45 45 45 45 100’ Children 1—3y Males 9—13y 14—18y 19—3Oy 31—50y 51—70y >70y 15’ 35* 35’ 35’ 30* 30’ 1’ 3, 4* 4* 4, 4* 1.5’ 1.9’ 2.2’ 2.3’ 2.3’ 2.3’ 2.3’ Females 9—13y 14—18y 19—3Oy 31—SOy 51—7Oy >70y 24* 25* 25* 20’ 20’ 2’ 3’ 3* 3* 3’ 3* 120 750 150 150 150 750 1,000 7,000 1,000 3’ 3’ 3* 220 220 220 27 27 27 400 350 360 2.0’ 2.0’ 2.0’ 50 50 50 7,250 700 700 60 60 60 72 11 11 1,300 7,300 1,300 3’ 290 290 290 70 9 9 360 310 320 2.6’ 2.6* 50 50 50 1,250 700 700 70 70 70 13 72 12 F Pregnancy l4—l8y 19—30y 31—50y 1.6* 700 890 900 900 900 900 30’ 30’ 3,8’ 4.7’ 4.7’ 2.3’ 2.3’ 2.3’ 2.0’ 1.8’ 2.3’ 2.3’ 2.3* 1.8’ Lactation 14—18y l9—30y 31—SOy 45’ 45’ 3’ 3’ Note:This table (taken from the DRI reports, see www.nap.edu) present5 Recommended Dietary Allowances (RDAs) in bold type and Adequate Intakes (Als) in ordinary type followed by an asterisk (1. An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97—98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an Al is usually developed. For healthy breast-fed infants, an Al is the mean intake. The Al for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake. 2.6’ 5.1’ 5.1* 5.1’ Data from: DIETARY REFERENCE INTAKES series, National Academies Press. Copyright ©1 997, 1998, 2000,2001, 2005, and 2011, by the National Academy of Sciences.These reports may be accessed via www.nap.edu. Courtesy of the National Academies Press, Washington, DC. Reprinted with permission. Dietary Reference Intakes: RDAAI* LTJI1A’. i.i’ItNd’iil!1 flht’. / / Infants 0—6 mc 6—12 mo 0.7* 0.8* Children l—3y 4—8y 1.3* 1.7* Males 9—13y l4—18y 19—30y 31—5Oy 51—70 y > 7Oy Females 9—13y l4—18y 19—3Oy 31—SOy 51—7Oy >70y Pregnancy l4—l8y 19—3Oy 3l—5Oy Lactation l4—l8y l9—3Oy 3l—5Oy NDC ND 31* 30* 44* 4.6* 0.5* 0.5* 9 1* 17.0 f30 130 19* 25* ND ND 7* 10* 0.7* Q,9* 73 79 2.4* 33* 37* 37* 37* 3,7* 730 730 130 730 730 130 31* 38* 38* 38* 30* 30* ND ND ND ND ND ND 12* 16* 17* 17* 14* 14* 1.2* 1.6* 1.6* 1.6* 1.6* 1.6* 34 52 56 56 56 56 2.1* 2.3* 2.7* 2.7* 2.7* 2.7* 130 130 730 130 130 730 26* 26* 25* 25* 27* 21* ND ND ND ND ND ND 10* 11* 12* 12* 11* 11* 1.0* 1.1* 1.1* 1.1* 77* 77* 34 46 46 46 46 46 3.0* 3.0* 3.0* 775 775 175 28* 28* 28* ND ND ND 73* 13* 13* 7,4* 14* 74* 77 77 77 3•$* 3.8* 3.8* 270 270 270 29* 29* 29* ND ND ND 13* 13* 73* 1.3* 13* 73* 77 77 77 60* 95* Note:This table (taken from the DRI reports, see www.nap.edu) presents Recommended Dietary Allowances (RDA) in bold type and Adequate Intakes (Al) in ordinary type followed by an asteri5k (f). An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97—98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an Al is usually developed. For healthy breast-fed infants, an Al is the mean intake. The Al for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake. a Total Water includes all water contained in food, beverages, and drinking water. Based on g protein per kg of body weight for the reference body weight, e.g., for adults 0.8 g/kg body weight for the refer ence body weight. Not determined. Data from: DIETARY REFERENCE INTAKES FOR ENERGY, CARBOHYDRATES, FIBER, FAT, FATTY ACIDS, CHOLESTEROL, PROTEIN, AND AMINO ACIDS (MACRONUTRIENTS), National Academies Press. Copyright ©2002/2005 by the National Academy of Sciences. DIETARY REFERENCE INTAKES FOR WATER, POTASSIUM, SODIUM, CHLORIDE, AND SULFATE, National Academies Press. Copyright 2005 by the National Academy of Sciences. These reports may be accessed via www.nap.edu. Courtesy of the National Academies Pre5s, Washington, DC. Reprinted with permission. / Dietary Reference Intakes: RDA,AI* / //‘ / ,./ ,/ / % // / ,.•/ /‘ // % .1. // /1 S / /1 / /1 / // Ij*;///;/ / /i Infants 0—6 ma .* /M ‘,I/’’ %./ /$ /1 I // I ./.. Z ,‘ / ./ /‘_ /j’ ‘ ‘ ,/ // // 400* 40* 10* 4* 2.0* 0.2* 0.3* 2* 0.1* 65* 0.4* 1.7* 5* 125* 6-12 ma 500* 50* 10* 5* 2.5* 0.3* 0.4* 4* 03* 80* 0.5* 1.8* 6* 150* Children 1—3 y 4-8y 300 400 75 25 75 75 6 7 30 55* 0.5 0.6 0.5 0.6 6 8 0.5 0.6 750 200 0.9 1.2 2* 3* 8* 12* 200* 250* 45 75 90 90 90 90 75 75 75 75 75 20 17 15 15 15 75 75 60 75* 120* 120* 120* 120 0.9 7.2 7.2 7.2 7.2 7.2 0.9 7.3 7.3 1.3 1.3 1.3 72 16 76 76 16 16 1.0 1.3 1.3 1.3 7.7 7.7 300 400 400 400 400 400 1.8 2.4 2.4 2.4 2Ah 4* 5* 5* 5* 5* 5* 20 25* 30* 30* 30* 30* 375* >70y 600 900 900 900 900 900 550’ 550’ 550’ 550’ 550’ Females 9—13y 14—18 y 19—30y 31—5Oy 5l—70y >7Oy 600 700 700 700 700 700 45 65 75 75 75 75 15 15 75 15 15 20 71 75 75 75 15 75 60’ 75* 90’ 90* 0.9 1.0 7.7 7.7 7.7 7.1 72 74 74 74 74 14 7.0 7.2 7.3 7.3 1.5 7.5 300 400’ 400’ 400’ 400 400 7.8 2.4 2.4 2.4 2A” 4* 5* 90’ 90’ 0.9 1.0 7.7 1.7 1.7 7.7 20’ 25’ 30’ 30’ 30* 375* 400’ 425’ 425’ 425* 30’ 425’ 750 770 770 80 85 85 75 75 75 75 75 75 75’s 90’ 90’ 7.4 7.4 7.4 1.4 7.4 7.4 78 78 18 7.9 1.9 1.9 60& 60& 600 2.6 2.6 2.6 6’ 6* 6* 30* 30* 30’ 450’ 450’ 45Q* 1,200 7,300 7,300 175 720 120 15 75 75 79 19 19 75* 90* 90* 7•4 7.4 7.4 1.6 7.6 7.6 77 77 17 2.0 2.0 2.0 500 500 500 2.8 2.8 2.8 7* 7* 7* 35* 35* 35* 550* 550* 550* Males 9—13y l4—18y 19—30y 31—50y 51—by Pregnancy 14—18y l9—30y 31—50y Lactation 14—18y l9—30y 31—SOy Note:This table (taken from the DRI reports, see www.nap.edu) presents Recommended Dietary Allowances (RDAs) in bold type and Adequate Intakes (Als) in ordinary type followed by an asterisk (‘I. An RDA is the average daily dietary intake level sufficient to meet the nutrient requirements of nearly all (97—98 percent) healthy individuals in a group. It is calculated from an Estimated Average Requirement (EAR). If sufficient scientific evidence is not available to establish an EAR, and thus calculate an RDA, an Al is usually developed. For healthy breast-fed infants, an Al is the mean intake. The Al for other life stage and gender groups is believed to cover the needs of all healthy individuals in the groups, but lack of data or uncertainty in the data prevent being able to specify with confidence the percentage of individuals covered by this intake. As retinal activity equivalents tRAEs). 1 RAE = 1 p.g retinol, 12 g 3-carotene, 24 p.g cs-carotene, or 24 .cg p-cryptoxanthin. The RAE for dietary provitamin A carotenoids is two-fold greater than retinol equivalents IRE), whereas the RAE for preformed vitamin A is the same as RE. b As cholecalciferol. 1 pg cholecalciferol = 40 lU vitamin D. Under the assumption of minimal sunlight. As cs-tocopherol. c*-Tocopherol includes RRR-cs-tocopherol, the only form of cs-tocopherol that occurs naturally in foods, and the 2R-stereoi5omeric forms of cc-tocopherol (RRR-, RSR-, RRS-, and R5S-cs-tocopherol) that occur in fortified foods and supplements, It does not include the 2S-stereoisomericformsofu-tocopherol(SRR-,55R-,SRS-, and SSS-cs-tocopherol), also found in fortified foods and supplement5. / / L “.*“.*/././,.‘-/.* “ . /1/ ///c/ .$. / / 2•4h 5* 5* 5* 5* As niacin equivalents (NE). 1 mg of niacin = 60 mg of tryptophan; 0—6 months = preformed niacin (not NE). ‘As dietary folate equivalents (DEE). 1 DEE = 1 pg food folate = 0.6 pg of folic acid from fortified food or as a supplement consumed with food = 0.5 pg of a supplement taken on an empty stomach. Although Als have been set for choline, there are few data to assess whether a dietary supply of choline is needed at all stages of the life cycle, and it may be that the choline requirement can be met by endog enous synthesis at some of these stages. Because 10 to 30 percent of older people may malabsorb food-bound B12, it is advisable for those older than 50 years to meet their RDA mainly by consuming foods fortified with 8,2 or a supplement containing 812. ‘In view of evidence linking folate intake with neural tube defects in the fetus, it is recommended that all women capable of becoming pregnant consume 400 pg from supplements or fortified foods in addition to intake of food folate from a varied diet. It is assumed that women will continue consuming 400 pg from supple ments or fortified food until their pregnancy is confirmed and they enter prenatal care, which oriinarily occurs after the end of the periconcep tional period—-the critical time for formation of the neural tube. Data from: DIETARY REFERENCE INTAKES series, National Academies Press. Copyright ©1 997, 1998,2000,2001,2005, and 2011, by the National Academy of Science5.These reports may be accessed via www.nap.edu. Courtesy of the National Academies Press, Washington, DC. Reprinted with permission. -