國立成功大學 行為醫學研究所 碩士論文 焦慮症患者對於情緒干擾面孔之負向促發 Negative Priming of Emotional Distracting Faces in Individuals with Anxiety Disorders 研 究 生 : 指 導 教 授 : 洪 友 雯 謝 淑 蘭 博士 柯 慧 貞 博士 中華民國 93 年 7 月 1 日 3 ! 4 5 6 7 1. Probe Detection Task(PDT) Cancer Apple Prime Probe 8 2. Deployment of Attention Task (DOAT) sky die Prime 1 9 Probe Green (Traditional Stroop Task) Red Cancer (Emotional Stroop Task) Loser Apple 2 10 11 A A E E D D H H Z Z F F (Tipper&Cranston, 1985) 3 12 ABABA ABABA CDCDC ZAZAZ (Flanker paradigm. Neill, Lissner, &Beck, 1990) 4 13 14 15 16 17 18 1. (SA) 30 21 22 29.17 8.69 16.27 1.91 34.33 14.43 15.57 1.99 33.91 9.58 15.18 1.92 19 35.57 9.22 45.71 9.46 44.32 13.13 (TA) 38.00 7.79 54.86 9.54 51.91 12.82 20 (duration=750ms) (answer= same) RT RSI=300ms (duration=750ms) (answer= same) 21 (answer= same) (answer= different) 5 : 22 23 24 25 26 27 28 29 1300 1200 1100 1000 900 30 ( ) . 40 30 20 0 -20 30 ( ) 31 32 33 34 35 36 37 American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders. 4rd ed. TR (DSM-IV-TR). Washington DC: American Psychiatric Association. Amir, N., McNally, R. J., Riemann, B. C., Burns, J., Lorenz, M., & Mullen, J. T. (1996). Suppression of the emotional Stroop effect by increased anxiety in patients with social phobia. Behaviour Research and Therapy, 34(11/12), 945-948. 38 Bradley, B. P., Mogg, K., & Lee, S. C. (1997). Attentional biases for negative information in induced and naturally occurring dysphoria. Behaviour Research and Therapy, 35(10), 911-927. Bradley, B. P., Mogg, K., & Millar, N. (1997). Attentional biases for emotional faces. Cognition and Emotion, 11(1), 25-42. Bradley, B. P., Mogg, K., Falla, S. J., & Hamilton, L. R. (1998). Attentional bias for threatening facial expressions in anxiety: Manipulation of stimulus duration. Cognition and Emotion, 12(6), 737-753. Charney, D. S., Nestler, E. J., & Bunney, B. S. (Eds.) (1999). Neurobiology of mental illness. New York: Oxford University Press. Cirneci, D. & Merloi, A. (2000). Computational modeling of selective attention in anxiety. Cognitie Creier Comportament, 4(4), 371-386. Damian, M. F. (2000). Semantic negative priming in picture categorization and naming. Cognition, 76, B45-B55. David, A. S. (1995). Negative priming (cognitive inhibition) in psychiatric patients: effect of neuroleptics. The Journal of Nervous and Mental Disease, 183(5), 337-339. Egloff, B., & Hock, M. (2001). Interactive effects of state anxiety and trait anxiety on emotional Stroop interference. Personality and Individual Differences, 31, 875-882. Ekman, P., & Davidson, R. J. (Eds.). (1994). The nature of emotion: Fundamental questions. New York: Oxford Oxford University Press. Ellis, A. W. & Young, A. W. (1998). Human cognitive neuropsychology: A textbook with readings. UK: Psychology Press. Enright, S. J. & Beech, A. R. (1993a). Further evidence of reduced inhibition in 39 obsessive-compulsive disorder. Personality and Individual Differences, 14, 387-395. Enright, S. J. & Beech, A. R. (1993b). Reduced cognitive inhibition in obsessive compulsive disorder. British Journal of Clinical Psychology, 32, 67-74. Enright, S. J., Beech, A. R., & Claridge, G. S. (1995). A further investigation of cognitive inhibition in obsessive-compulsive disorder and other anxiety disorders. Personality and Individual Differences, 19(4), 535-542. Everhart, D. E., & Harrison, D. W. (2000). Psychobiology, 28(1), 90-98. Eysenck, M. W. (1988). Anxiety and attention. Anxiety Reseatch, 1, 9-15. Foa, E. B., & Ilai, D., McCarthy, P. R., Shoyer, B., & Murdock, T. (1993). Information processing in obsessive-compulsive disorder. Cognitive Therapy and Research, 17, 173-189. Fox, E. (1994). Attentional bias in anxiety: a defective inhibition hypothesis. Cognition and Emotion, 8(2), 165-195. Fox, E. (1993a). Attentional bias in anxiety: Selective or not? Behaviour Research and Therapy, 31(5), 487-493. Fox, E. (2002). Processing emotional facial expressions: The role of anxiety and awareness. Cognitive, Affective, & Behavioral Neuroscience, 2(1), 52-63. Gray, J. A. & McNaughton, N. (2000). The neuropsychology of anxiety: An enquiry into the functions of the septo-hippocampal system (2rd ed.). New York: Oxford University Press. Greenberg, B. D., Murphy, D. L., & Rasmussen, S. A. (2000). Neuroanatomically based approaches to obsessive-compulsive disorder : neurosurgery and transcranial magnetic stimulation. Psychiatric Clinical North American, 23(3): 671. 40 Hoenig, K., Hochrein, A., Muller, D. J., & Wagner, M. (2002). Different negative priming impairments in schizophrenia and subgroups of obsessive-compulsive disorder. Psychological Medicine, 32, 459-468. Hope, D. A., Rapee, R. M., Heimberg, R. G., & Dombeck, M. J. (1990). Representations of the social phobia: Vulnerability to social threat. Cognitive Research and Therapy, 14, 177-189. Houghton, G., & Tipper, S. P. (1994). A model of inhibitory mechanisms in selective attention. In D. Dagenbach, & T. H. Carr (Eds.), Inhibitory process in attention, memory, and language. New York: Academic Press. Houghton, G., Tipper, S. P., Weaver, B., & Shore, D. I. (1996). Inhibition and interference in selective attention: Some test of a neural network model. Visual cognition, 3(2), 119-164. Houwer, J. D., Rothermund, K., & Wentura, D. (2001). Menmory and Cognition, 29(7), 931-939. Humphreys, G. W., Duncan, J., & Treisman, A. (Eds.). (1999). Attention, space and Action: studies in cognitive neuroscience. New York: Oxford University Press. Ingram, R. E., & Price, J. M. (Eds.). (2001). Vulnerability to psychopathology. New York London: The Guilford Press. Khurana, B. (2000). Not to be and then to be: visual representation of ignored unfamiliar faces. Journal of Experimental Psychology: Human Perception and Performance, 26(1), 246-263. Kindt, M., & Brosschot, J. F. (1998). Cognitive inhibition in phobia. British Journal of Clinical Psychology, 37, 103-106. Kindt, M., & Brosschot, J. F. (1998). Cognitive avoidance in phobia. Journal of Psychopathology and Behavioral Assessment, 20(1), 43-55. 41 Kolb, B., & Whishaw, I. Q. (1996). Human neuropsychology (4rd ed.). New York: W. H. Freeman and Company. Kramer, A. F., & Strayer, D. L. (2001). Psychology and Aging, 16(4), 580-587. Lane, R. D., & Nadel, L (Eds.). (2000). Cognitive neuroscience of emotion. New York: Oxford Oxford University Press. Ledoux, J. Cognitive-emotional interactions: listen to the brain. In: Lane RD, Nadel L eds. Cognitive Neuroscience of emotion. (2000). New York: Oxford University Press. Logan, A. C., & Goetsch, V. L. (1993). Attention to external threat cues in anxiety states. Clinical Psychology Review, 13, 541-559. Lundh, L. G., Wikstrom, J., Westerlund, J., & Ost, L. G. (1999). Preattentive bias for emotional information in panic disorder with agoraphobia. Journal of Abnormal Psychology, 108(2), 222-232. MacDonald, P. A., Antony, M. M., MacLeod, C.M., Swinson, R. P. (1999). Negative priming for obsessive-compulsive checkers and noncheckers. Journal of Abnormal Pshchology, 108(4), 679-686. MacLeod, C., & Mathews, A., & Tata, P. (1986). Attentional bias in emotional disorders. Journal of Abnormal Psychology, 95, 15-20. MacLeod, C. M., & Mathews, A. (1988). Anxiety and the allocation of attention to threat. The Quarterly Journal of Psychology, 95, 15-20. MacLeod, C. M., & MacDonald, A. (2000). Interdimensional interference in the Stroop effect: uncovering the cognitive and neural anatomy of attention. Trends in Cognitive Sciences, 4(10), 383-391. Macqueen, G. M., Galway, T., Goldberg, J. O., & Tipper, S. P. (2003). Impaired distractor inhibition in patients with schizophrenia on a negative priming task. 42 Psychological Medicine, 33, 121-129. Mathews, A., & MacLeod, C. (1985). Selective processing of threat cues in anxiety states. Behavior Research and Therapy, 23, 563-569. Mathews, A. (1993). Attention and memory for threat in anxiety. In Krohne, H. Walter (Eds.), Attention and avoidance: Strategies in coping with averisiveness. WA, US: Hogrefe & Huber Publishers. Mathews, A., May, J., Mogg, K., & Eysenck, M. (1990). Attentional bias in anxiety: Selective search or defective filtering? Journal of Abnormal Psychology, 99(2), 166-173. Mathews, A. (1993). Biases in processing emotional information. The Psychologist: Bulletin of the British Psychological Society, 6, 493-499. Mathews, A., & MacLeod, C. (1994). Cognitive approaches to emotion and emotional disorders. Annual Review of Psychology, 45, 25-50. Mathews, A., Mackintosh, B., & Fulcher, E. P. (1997). Cognitive biases in anxiety and attention to threat. Trends in Cognitive Sciences, 1(9), 340-345. Martin, M., Williams, R. M., & Clark, D. (1991). Does anxiety lead to selective processing of threat-related information? Behaviour Research and Threapy, 29, 147-160. Maxmen, J. S., & Ward, N. G. (1995). Essential psychopathology and its treatment: Second edition revised for DSM-IV. New York London: W. W. Norton & Company. May, C. P., Kane, M. J., & Hasher, L. (1995). Determinants of negative priming. Psychological Bulletin, 118(1),35-54. McNally, R. J., Riemann, B. B., & Kim, E. (1990). Selective processing of threat cues in panic disorder. Behaviour Research and Therapy, 28, 407-412. 43 McNally, R.J., Wilhelm, S., Buhlmann, U., & Shin, L. M. (2001). Cognitive inhibition in obsessive-compulsive disorder: application of a valence-based negative priming paradigm. Behavioural and Cognitive Psychotherapy, 29, 103-106. Milliken, B., Tipper, S. P., & Weaver, B. (1994). Negative Priming in a spatial localization task: Feature mismatching and distractor inhibition. Journal of Experimental Psychology: Human Perception and Performance, 20(3), 624-646. Mogg, K., Mathews, A., & Weinman, J. (1987). Memory bias in clinical anxiety. Journal of abnormal psychology, 96, 94-98. Mogg, K., Mathews, A., & Weinman, J. (1989). Selective processing of threat cues in anxiety states: A replication. Behaviour Research and Therapy, 27, 317-323. Mogg, K., Mathews, A., Bird, C., Macgregor-Morris, R. (1990). Effects of stress and anxiety on the processing of threat stimuli. Journal of Personality and Social Psychology, 59, 1230-1237. Mogg, K., & Bradley, B. P. (1998). A cognitive-emotional analysis of anxiety. Behavior Research and Therapy, 36, 809-848. Mogg, K., McNamara, J., Powys, M., Rawlinson, H., Seiffer, A., & Bradley, B. P. (2000 . Selective attention t threat: A test of two cognitive models of anxiety. Cognition and Emotion, 14(3), 375-399. Morris, J. S., Friston, K. J., Buchel, C., Frith, C. D., Young, A. W., Calder, A. J., & Dolan, R. J. (1998). Aneuromodulatory role for the human amygdala in processing emotional facial expressions. Brain, 121, 47-57. Neill, W. T., Valdes, L. A. & Terry, K. M. (c1995). Selective attention and the inhibitory control of cognition. In F. N. Dempster, & C. J. Brainerd (Eds.), Interference and inhibition in cognition. San Diego: Academic Press. 44 Neill, W. T., Lissner, L. S., & Beck, J. L. (1990). Negative priming in same-different matching: further evidence for a central locus of inhibition. Perception and Psychophysics, 48(4), 398-400. Paquet, L. (2001). Eliminating flanker effects and negative priming in the flankers task: Evidence for early delection. Psychonimic Bulletin and Review, 8(2), 301-306. Skosnik, P.D., Chatterton Jr. R. T., Swisher, T., & Park, S. (2000). Modulation of attentional inhibition by norepinephrine and cortisol after psychological stress. International Journal of Psychophysiology, 36, 59-68. Sadock, B. J. & Sadock, V. A. (2003). Synopsis of Psychiatry. 9rd ed. Philadelphia: Lippincott Williams & Wilkins. Speilberg, C. D. (1999). Measuring anxiety and anger with the State-Trait Anxiety Inventory(STAI) and the State-Trait Anger Expression Inventory(STAXI). In Marnish, M. E. (Eds), The use of psychological testing for treatment planning and outcomes assessment, pp993-1021. Steel, C., Haworth, E. J., Peters, E., Hemsley, D. R., Sharma, T., Gray, J. A., Pickering, A., Gregory, L., Simmons, A., Bullmore, E. T., & Williams, S. C. R. (2001). Neuroimaging correlates of negative priming. Brain imaging, 12(16), 3619-3624. Stein, D. J. (2004). Clinical Manual of Anxiety Disorders. Arlington: American Psychiatric Publishing, Inc. Sturgill, D. S., Ferraro, F. R. (1997). Predicting negative priming: effects of schizotypy, cognitive failures, and anxiety. Personality and Individual Differences, 23(2), 291-304. Taghavi, M.R., Neshat-Doost, H. T., Moradi, A. R., & Yule, W. (1999). Biases in 45 visual attention in children and adolescents with clinical anxiety and mixed anxiety-depression. Journal of Abnormal Child Psychology, 27(3), 215-223. Tipper, S. P., & Cranston, M. (1985). Selective attention and priming: inhibitory and facilitatory effects of ignored primes. The Quarterly Journal of Experimental Psychology, 37A, 591-611. Tipper. S. P. (2001). Does negative priming reflect inhibitory mechanisms? A review and integration of conflicting views. The Quarterly Journal of Experimental Psychology, 54A(2), 321-343. Watts, F. N., McKenna, F. P., Sharrock, R., & Trezise, L. (1986). Color naming of phobia-related words. British Journal of Psychology, 77, 97-108. Wells, A., & Mathews, G. (1994). Attention and emotion: A clinical perspective. UK: Lawrence Erlbaum Associates Ltd. Williams, J. M. G., Mathews, A., & MacLeod, C. (1996). The emotional Stroop task and psychopathology. Psychological Bulletin, 120(1), 3-24. Williams, J. M. G., Watts, F. N., MacLeod, C., & Mathews, A. (1997). Cognitive psychology and emotional disorders (2re ed.). New York: John Wiley & Sons Inc. Yee, P. L., Santoro, K. E., Grey, A. L., & Woog, V. (2000). Memory and Cognition, 28(8), 1429-1436. 46 ______________________ 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. _______________________ ………………………………………(1) ……………………………………………(1) ……………………………………………(1) …………………………………………(1) …………………………………………(1) ……………………………………………(1) …………………(1) ..………………………………..………(1) (2) (2) (2) (2) (2) (2) (2) (2) (3) (3) (3) (3) (3) (3) (3) (3) (4) (4) (4) (4) (4) (4) (4) (4) ……………………………………………(1) ………………………………………(1) …………………………………………(1) …………………………………………(1) ………………………………………(1) ………………………………………(1) ……………………………………………(1) …………………………………………(1) ……………………………………………(1) ……………………………………………(1) ……………………………………………(1) …………………………………………(1) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) 47 ( ______________________ 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. ) _______________________ ………………………………………………(1) …………………(1) …………………………………………(1) ……………………………(1) ……………………………………(1) ………………………………………(1) …………………………………(1) ……(1) …………………(1) …………………………………………………(1) …………………………(1) ………………………………………(1) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (2) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (3) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) (4) 34. 35. 36. 37. 38. 39. …………………………………………………(1) ………………………………(1) ………………………(1) …………………………………………………(1) …(1) ……………(1) …………………………………………(1) (2) (2) (2) (2) (2) (2) (2) (3) (3) (3) (3) (3) (3) (3) (4) (4) (4) (4) (4) (4) (4) 40. ….(1) (2) (3) (4) 48 Negative Priming of Emotional Distracting Faces in Individuals with Anxiety Disorders 49