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CRR HISTOLOGY Cardiovascular and
Lymphatic Systems
SELF-ASSESSMENT
NOTE: The following questions are designed for introductory drill (i.e., to
practice basic vocabulary and description of cell structure and function in
the cardiovascular and lymphatic systems). These questions do not necessarily represent the
quality of questions which will appear on the CRR Unit evaluation.
(reference: https://histology.siu.edu/crr/cvguide.htm).
Other topics:
SAQ slides
SAQ, Introduction -- microscopy, cells, basic tissue types, blood cells.
SAQ, Respiratory System.
SAQ, Renal System.
Multiple choice questions.
Point to an answer. Green color and bold indicates "CORRECT." Red color and italics
indicates "Wrong answer."
(NOTE: In cases where all of the responses are correct, only "all of the above" will be
indicated as correct.)
1. The most abundant tissue element forming the media of the aorta is:
a. cardiac muscle.
b. smooth muscle.
c. collagen.
d. elastin.
e. cartilage.
2. The most abundant tissue element forming the media of small, muscular arteries is:
a. cardiac muscle.
b. smooth muscle.
c. collagen fibers.
d. elastic fibers.
e. cartilage.
3. Blood platelets are most closely associated with:
a. oxygen transport.
b. antibody production.
c. antigen recognition.
d. phagocytosis.
e. clotting.
4. The muscular layer of blood vessels is called:
a. tunica intima.
b. tunica media.
c. tunica adventia.
d. endothelium.
e. mesothelium.
5. A prominent inner elastic membrane (internal elastic lamina), often appearing in cross
section as a wavy or sinuous line, is characteristic of:
a. muscular arteries.
b. small veins.
c. large veins.
d. venules.
e. capillaries.
6. The inner layer of a blood vessel wall, characterised by a simple squamous endothelium
supported by a thin layer of connective tissue, is the:
a. adventitia.
b. external elastic lamina.
c. media.
d. internal elastic lamina.
e. intima.
7. Mesothelium is:
a. simple squamous epithelial tissue.
b. stratified squamous epithelial tissue.
c. simple cuboidal epithelial tissue.
d. stratified cuboidal epithelial tissue.
e. simple columnar epithelial tissue
8. Endothelium is:
a. simple squamous epithelial tissue.
b. stratified squamous epithelial tissue.
c. simple cuboidal epithelial tissue.
d. stratified cuboidal epithelial tissue.
e. simple columnar epithelial tissue
9. Endothelium lines all of the following EXCEPT:
a. arteries.
b. veins.
c. capillaries.
d. lymphatic vessels.
e. glandular ducts.
10. Mesothelium lines:
a. the respiratory tract.
b. the urinary tract.
c. the peritoneal, pleural and pericardial cavities.
d. the nasal cavity.
e. the oral cavity.
11. Which organ is lined by endothelium on the inside and mesothelium on the outside?
a. esophagus.
b. tonsil.
c. intestine.
d. heart.
e. stomach.
12. Which cell junction, located at intercalated disks, is responsible for electrical
communication between cardiac muscle cells?
a. macula adherens.
b. zonula adherens.
c. zonula occludens.
d. desmosome.
e. gap junction.
13. Lymphoid tissue in the intestinal mucosa takes the form of:
a. tonsils.
b. lymph nodes.
c. crypts.
d. lymph nodules.
e. splenic cords.
14. Hassall's corpuscles are a unique and characteristic feature of:
a. spleen.
b. thymus.
c. lymph nodes.
d. bone marrow.
e. tonsils.
15. Reticular fibers (a form of type III collagen) form a supporting meshwork for cells in:
a. spleen.
b. lymph nodes.
c. bone marrow.
d. all of the above.
16. Smooth muscle is most substantial in:
a. the epicardium of the heart.
b. the media of elastic arteries.
c. the media of muscular arteries.
d. the myocardium of the heart.
e. arterioles.
17. The sino-atrial (SA) node, the atrio-ventricular (AV) node, and the Purkinje fibers of the
myocardium all consist of specialized:
a. endothelial cells.
b. fibroblasts.
c. nerve cells.
d. smooth muscle cells.
e. cardiac muscle cells.
18. Purkinje fibers:
a. generate electrical impulses.
b. conduct electrical impulses through the myocardium.
c. synchronize the heartbeat.
d. are found along the innermost layer of the myocardium.
e. all of the above
19. Thick, collagenous rings located at the sites of origin of large vessels and valves of the
heart are referred to as:
a. the fibrous skeleton of the heart.
b. the sino-atrial nodes.
c. intercalated discs.
d. cusps of the valves.
e. none of the above
20. Heart valves normally consist of an endothelial surface covering:
a. cardiac muscle fibers.
b. hyaline cartilage.
c. loose areolar connective tissue.
d. fibrocollagenous and fibroelastic connective tissue.
e. adipose connective tissue.
21. Vasa vasorum are:
a. blood vessels of the myocardium.
b. nerves that supply the blood vessels.
c. nerves of the heart.
d. blood vessels within the walls of the blood vessels.
e. blood vessels of the endocardium.
22. Blood vessels are normally encountered in all of the following EXCEPT:
a. epicardium.
b. myocardium.
c. endocardium.
d. wall of aorta.
e. respiratory mucosa.
23. Which of the following features is a normal component of epicardium but NOT of
endocardium?
a. adipocytes
b. collagen.
c. elastin
d. fibroblasts
e. simple squamous epithelial tissue
24. Intercalated discs:
a. include desmosomes.
b. are found at the boundary between adjacent cardiac muscle cells.
c. include gap junctions.
d. may appear as dark or light bands by light microscopy.
e. all of the above
25. The junctions that are the basis for electrical conduction from one cardiac muscle cell to
another are:
a. desmosomes.
b. occluding junctions.
c. gap junctions.
d. adhering junctions.
26. "Short-cuts" between arteries and veins are:
a. capillaries.
b. sinusoids.
c. lymph vessels.
d. arterio-venous anastomoses.
e. venules.
27. Undifferentiated cells around the perimeter of capillaries are:
a. pericytes.
b. parasites.
c. fenestrations.
d. endothelial cells.
e. basal lamina.
28. Continuous endothelium is found in:
a. endocrine organs.
b. kidney.
c. lung.
d. spleen.
e. all of the above
29. Fenestrated endothelium is found in:
a. endocrine organs.
b. kidney.
c. intestinal villi.
d. spleen.
e. all of the above
30. Lymphatic nodules are found in:
a. cortex of lymph nodes.
b. tonsils.
c. spleen.
d. respiratory and gastrointestinal mucosa.
e. all of the above
31. Lymphatic nodules are NOT found in:
a. cortex of lymph nodes.
b. tonsils.
c. spleen.
d. respiratory and gastrointestinal mucosa.
e. thymus.
32. Red and white pulp describes tissue of the:
a. lymphatic nodules.
b. bone marrow.
c. thymus.
d. spleen.
e. lymph node.
33. The germinal center of a lymph nodule is:
a. comprised of densely packed lymphocytes.
b. the active site of lymphocyte proliferation.
c. comprised mainly of T-cells.
34. Red pulp of the spleen:
a. is comprised of lymphatic nodules.
b. is comprised of B-cells .
c. is comprised of splenic cords, venous sinuses, and reticular fibers.
d. is comprised of elastic connective tissue.
35. Cells which mature in the thymus and then enter circulation are:
a. thymic corpuscles.
b. thymic nurse cells.
c. plasma cells.
d. T-lymphocytes.
e. epitheliocytes.
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SIUC / School of Medicine / Anatomy / David King
https://histology.siu.edu/crr/SAQcv.htm
Last updated: 8 September 2021 / dgk