RESPIRATORY RESPIRATORY ALKALOSIS ALKALOSIS Presentation by: BSN 3A OVERVIEW Respiratory alkalosis -occurs when the levels of carbon dioxide and oxygen in the blood are not balanced. When you breathe too fast or too deep and carbon dioxide levels drop too low. Note: The arterial blood profile seen in respiratory alkalosis is: • • • INCREASE IN PH DECREASE IN HCO3 DECREASE IN PCO2 What is Hyperventilation? Hyperventilation is rapid or deep breathing, usually caused by anxiety or panic. This over breathing, as it is sometimes called, may actually leave you feeling breathless. When you breathe, you inhale oxygen and exhale carbon dioxide. Excessive breathing may lead to low levels of carbon dioxide in your blood, which causes many of the symptoms that you may feel if you hyperventilate. CLASSIFIED IN TWO CATEGORIES: Acute respiratory alkalosis- the PaCO2 level is below the lower limit of normal and the serum pH is alkalemic. Chronic respiratory alkalosis- the PaCO2 level is below the lower limit of normal, but the pH level is relatively normal or near normal due to compensatory mechanisms. MNEMONIC OF TACHYPNEA Temperature increase (fever) Aspirin toxicity Controlled ventilation Hyperventilation (excessive respirations) HYsteria (anxiety) Pain, Pregnancy,Pneumonia Neurological injuries from a head injury or Embolism or Edema in the lungs Asthma due to hyperventilation stroke PATHOPHYSIOLOGY SIGNS AND SYMPTOMS What are the symptoms of respiratory alkalosis? You may experience: Breathlessness Dizziness Numbness and /or tingling in your fingertips, toes and lips Irritability Nausea Muscle spasms or twitching Fatigue Dizziness/lightheadedness Fainting (syncope) Chest discomfort Shortness of breath Tremors Confusion DIAGNOSTIC TEST/EXAM Arterial Blood Gas Basic Metabolic Panel Chest X-ray Pulmonary Function Tests DIAGNOSTIC TEST/EXAM The following laboratory studies that may be helpful are: Serum chemistries Complete blood count (CBC) Liver function test Cultures of blood, sputum, urine, and other sites Thyroid testing Beta-human chorionic hormone levels Drug screens and theophylline and salicylate levels DIAGNOSTIC TEST/EXAM Imaging studies These include the following: Chest radiography - Should be performed to help rule out pulmonary disease as a cause of hypocapnia and respiratory alkalosis Computerized tomography (CT) scanning of the chest - May be performed if chest radiography findings are inconclusive or a pulmonary disorder is strongly considered as a differential diagnosis Ventilation perfusion scanning - Can be considered in patients who are unable to undergo an intravenous contrast injection associated with CT scanning to assess the patient for pulmonary embolism Brain magnetic resonance imaging (MRI) - Can be considered if a central cause of hyperventilation and respiratory alkalosis is suggested and the initial brain CT scan findings are negative or inconclusive NURSING MANAGEMENT Monitor vital signs Monitor ABGs, primarily PaCO2; a value less than 35 mmHg indicates too little CO2 (carbonic acid) Be alert for signs of changes in neurologic, neuromuscular or cardiovascular functions. Encourage the anxious patient to verbalize fears Encourage the patient to take deep, slow breaths or breathe into a brown paper bag (inspire CO2). Keep the patient warm and dry MEDICAL MANAGEMENT For management of Panic and anxiety: Administer sedation as ordered to relax the patient and to reduce the intensity of panic attacks. Institute safety measures for the patient with vertigo or the unconscious patient. PHARMACOLOGIC MANAGEMENT Treatment for respiratory alkalosis depends on the underlying cause to reduce hyperventilation. Depending on the severity, your doctor may also prescribe medication. Examples of medications for hyperventilation include: Alprazolam (Xanax)- used to treat generalized anxiety disorder, symptoms of anxiety in the short term, panic disorder Doxepin- It is a prescription drug and used to treat mood disorders, such as depression and anxiety. Paroxetine (Paxil)- an oral tablet that can be used to treat depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, post-traumatic stress disorder, and premenstrual dysphoric disorder. Thank you for listening! REFERENCES https://emedicine.medscape.com/article/301680-overview https://my.clevelandclinic.org/health/diseases/21657-respiratoryalkalosis#:~: text=Respiratory%20alkalosis%20occurs%20when%20high, reduce%20the%20risk%20of%20hyperventilation. https://www.registerednursern.com/respiratory-alkalosis-nclexreview-notes-with-mnemonic-quiz-acid-base-imbalance-notes/ https://nurseslabs.com/respiratory-alkalosis-nursingmanagement/ https://www.slideshare.net/SiddharthSingh314/ alkalosis-77344859