BCS 110: Unit 1 Exam University Academic Honesty Policy: “I affirm that I will not give or receive any unauthorized help on this exam, and that all work will be my own.” Last Name __________________________ First Name __________________________ Answer all 50 of the following questions. Circle completely or write clearly only one answer per question. The duration of the exam is 50 minutes. Good luck! 1) In a biopsychology experiment, the subjects are _____ and behavior is the _____ variable. A) human, dependent B) human, independent C) nonhuman, dependent D) nonhuman, independent 2) Glial cells improve neuron function in many ways. For example, _____ provide myelin for one axon to secure conduction of action potentials, while ______ form electrical synapses with both a neuron and its target to ensure communication. A) oligodendrocytes and astrocytes B) oligodendrocytes and microglia C) Schwann cells and astrocytes D) Schwann cells and microglia 3) The sympathetic nervous system differs from the parasympathetic nervous system in a variety of ways including that sympathetic nerves exit _____ of the spinal cord and synapse on second-stage neurons ____ the spinal cord. A) from the middle, near to B) from the middle, far from C) from the ends, near to D) from the ends, far from 4) A neuron is at its resting membrane potential of -70 mV, and has a threshold for firing an action potential of -60 mV. All at the same time, it receives EPSPs at five dendrites each of 2mV amplitude. This is called ____, and the neuron ____. A) spatial summation, is not likely to fire B) spatial summation, will likely fire an action potential C) temporal summation, is not likely to fire D) temporal summation, will likely fire an action potential 5) Which of the following cells will give rise directly to the somatic nervous system? A) totipotent cells B) neural crest cells C) embryonic stem cells D) radial glial cells 6) In which of the following planes would a cut need to be made to divide in half the reticular formation (i.e. perpendicular to its long axis)? A) frontal B) sagittal C) horizontal D) cross-section 2 7) The neurons providing the input to the inferior peduncle of the cerebellum are _____ in shape and carry _____ signals. A) unipolar, sensory B) unipolar, motor C) multipolar, sensory D) multipolar, motor 8) A patient is exhibiting signs of depression. You suspect an injury to the ______. A) locus coerulus B) raphe nuclei C) substantia nigra D) ventral tegmental area 9) Which, if any, of the following statements about the equilibrium potential of an ion is false? A) It depends on the concentration of the ions inside and outside the cell. B) It depends on the charge of the ion. C) It is the voltage at which opposing diffusional and electrical forces are equal. D) It is the voltage at which ions stop flowing across the membrane. E) All the statements are correct. 10) The chemoaffinity hypothesis of long and short guidance cues was postulated to explain which stage of neurodevelopment? A) proliferation B) migration C) aggregation D) axon growth E) synapse refinement For the sets below, match each item on the left with the best choice from the items (answers) on the right. Write your answer on the line in front of the number. Some answers may be used multiple times, others not at all. With regard to the methods used in various disciplines of biopsychology to study the brain and behavior: B ______ 11) comparative psychology A) record activity of groups of neurons E ______ 12) neuropsychology B) knock out / knock in genes A ______ 13) psychophysiology C) apply electric stimulation A ______ 14) cognitive neuroscience D) locate neurotransmitters C ______ 15) physiological psychology E) run a test battery 3 With regard to the location of structures within the divisions of the brain: C ______ 16) superior colliculus A) metencephalon E ______ 17) inferior olive B) diencephalon D ______ 18) amygdala C) mesencephalon D ______ 19) substantia nigra D) telencephalon A ______ 20) trigeminal nucleus E) myelencephalon With regard to areas of the brain: pathways and functions E ______ 21) learning and memory (of this fig!) D ______ 22) cortex with inferior colliculus in ascending pathway D ______ 23) initiates pyramidal tract F ______ 24) thinking, planning D ______ 25) pain modulation D ______ 26) outputs to red nucleus G ______ 27) motor selection (cortical) D ______ 28) sensory decussation D ______ 29) motivation and reward center A ______ 30) target of ventral posterior nucleus With regard to the location and function of proteins in a neuron (answers graded independently): Loc Fnct Protein Location Function E ____ G ____ 31) sodium-potassium pumps A) dendrite G) resting potential D ____ H ____ 32) monoamines B) axon H) exocytosis D ____ H ____ 33) voltage-gated calcium channels C) soma I) concentration gradient B ____ K ____ 34) voltage-gated sodium channels E ____ I ____ 35) signal proteins D) axon terminal E) everywhere J) postsynaptic potentials K) action potentials 4 With regard to select functions of neurotransmitters in the central nervous system (CNS) and peripheral nervous system (PNS) (answers graded independently) CNS PNS D EB Neurotransmitter Function A) emotion, mood B) rest and digest C) alertness, energy D) learning and memory E) fight or flight _____ _____ 36) acetylcholine A _____ F _____ 37) serotonin F _____ C E _____ 38) epinephrine D _____ F _____ 39) glutamate C _____ C E _____ 40) norepinephrine F) none 41) Small is to big as a gyrus is to a A) sulcus B) lobe C) commissure D) fissure 42) In contrast to small neurotransmitters, large neurotransmitters produce signals in postsynaptic neurons by A) entering through gap junctions B) activating second messengers C) opening ion channels from the inside via G-proteins D) targeting metabotropic receptors 43) An individual suffers an injury that affects their hypothalamus. What would be a possible consequence of this accident? A) a loss of memory B) paralysis of the muscles of the face C) an unstable breath rate D) visual impairment 44) The neurons whose cell bodies are located in the ventral horns of the spinal cord carry _____ information, and are part of the _____ nervous system. A) afferent, central B) afferent, peripheral C) efferent, central D) efferent, peripheral 5 45) A male visits his doctor complaining of double vision due to an eye tremor that started after a fall from a ladder. Which cranial nerve is most likely involved with this purely motor problem? A) optic (II) B) trochlear (IV) C) facial (VII) D) glossopharyngeal (IX) 46) GABA receptors are permeable to (selective for) potassium ions. true / false 47) The limbic system includes structures in the telencephalon and mesencephalon, and regulates emotional responses to stimuli. true / false 48) Drugs that deactivate the autoreceptors on a neuron are _____ of its neurotransmitter. agonists / antagonists 49) An experimental drug treatment makes neurons leakier to sodium ions at rest. If nothing else changes, then neurons will be ______ likely to fire action potentials. more / less 50) One defining characteristic of neocortex is its columnar organization; these columns are oriented _____ to its pial surface. perpendicular / parallel 6