• The study of the structure of body parts and their relationships to one another • Where it is and what it is made of! • The study of the function of the body’s structural machinery • How it works! • The Highest Level • Made up of organ systems Consists of different __________ that work closely together • • • • • • _______________ Skeletal _______________ Nervous Endocrine Cardiovascular • • • • • Lymphatic/Immune Respiratory Digestive Urinary Reproductive – male and female Principal organs: Skin, hair, nails, cutaneous glands Principal organs: Bones, cartilages, ligaments Principal functions: Protection, water retention, thermoregulation, vitamin D synthesis, cutaneous sensation, nonverbal communication Principal functions: Support, movement, protective enclosure of viscera, blood formation, mineral storage, electrolyte and acid–base balance Integumentary system Skeletal system Principal organs: Lymph nodes, lymphatic vessels, thymus, spleen, tonsils Principal functions: Recovery of excess tissue fluid, detection of pathogens, production of immune cells, defense against disease Lymphatic system Principal organs: Skeletal muscles Principal functions: Movement, stability, communication, control of body openings, heat production Muscular system Principal organs: Nose, pharynx, larynx, trachea, bronchi, lungs Principal organs: Kidneys, ureters, urinary bladder, urethra Principal functions: Absorption of oxygen, discharge of carbon dioxide, acid–base balance, speech Principal functions: Elimination of wastes; regulation of blood volume and pressure; stimulation of red blood cell formation; control of fluid, electrolyte, and acid-base balance; detoxification Respiratory system Urinary system Principal organs: Brain, spinal cord, nerves, ganglia Principal functions: Rapid internal communication, coordination, motor control and sensation Principal functions: Hormone production; internal chemical communication and coordination Nervous system Endocrine system Principal organs: Teeth, tongue, salivary glands, esophagus, stomach, small and large intestines, liver, gallbladder, pancreas Principal functions: Nutrient break down and absorption. Liver functions include metabolism of carbohydrates, lipids, proteins, vitamins, and minerals; synthesis of plasma proteins; disposal of drugs, toxins, and hormones; and cleansing of blood. Digestive system Principal organs: Pituitary gland, pineal gland, thyroid gland, parathyroid glands, thymus, adrenal glands, pancreas, testes, ovaries Principal organs: Testes, epididymides, spermatic ducts, seminal vesicles, prostate gland, bulbourethral glands, penis Principal functions: Production and delivery of sperm; secretion of sex hormones Principal organs: Heart, blood vessels Principal functions: Distribution of nutrients, oxygen, wastes, hormones, electrolytes, heat, immune cells, and antibodies; fluid, electrolyte, and acid-base balance Circulatory system Principal organs: Ovaries, uterine tubes, uterus, vagina, mammary glands Principal functions: Production of eggs; site of fertilization and fetal development; fetal nourishment; birth; lactation; secretion of sex hormones Male reproductive system Female reproductive system • Made up of different types of __________ • Consists of similar types of _________ • Made up of __________ • Made up of ___________ Organism Organ system Tissue Organ Cell Macromolecule Organelle Atom Molecule • No two humans are exactly alike – 70% most common structure – 30% anatomically variant – Variable number of ___________ • Missing muscles, extra vertebrae, blood vessels – Variation in organ ___________ Normal Pelvic kidney Horseshoe kidney Normal Variations in branches of the aorta • __________________ – differentiation and growth • __________________ – producing copies of themselves; pass genes to offspring • __________________ – mutations: changes in genetic structure • __________________ composition – living matter is always compartmentalized into one or more cells • __________________ and movement – sense and react to stimuli • All the chemical reactions that occur in the body – Building reactions • ____________ – Breaking reactions • ____________ • The ability to maintain a relatively stable internal environment in an ever-changing outside world – Example: body temperature – State of the body fluctuates within limited range around a set point – ____________ feedback keeps variable close to the set point • Body senses a change and activates mechanisms to reverse it – dynamic equilibrium • Because feedback mechanisms alter the original changes that triggered them (temperature, for example), they are called feedback loops 1 Room temperature fallsto66°F(19°C) C10° 15°20°25° 6 Room cools down F50° 60°70°80° 2 C10° 15°20°25° F50° 60°70°80° 5 Thermostat shuts off furnace 4 Room temperature rises to 70°F (21°C) 3 Heat output Thermost atactivates furnace Room temperature (oF) 75 Furnace turned off at 70 oF 70 Set point 68 oF 65 Furnace turned on at 66 oF 60 Time • Example: Room temperature does not stay at set point of 68°F, it only averages 68°F Core body temperature Sweating 37.5 oC (99.5 oF) Vasodilation 37.0 oC (98.6 oF) 36.5 oC (97.7 oF) Set point Vasoconstriction Time Shivering • Example: Brain senses change in blood temperature – If too warm, vessels dilate (vasodilation) in the skin and sweating begins (heat-losing mechanism) – If too cold, vessels in the skin constrict (vasoconstriction) and shivering begins (heat-gaining mechanism) Person rises from bed Blood pressure rises to normal; homeostasis is restored Cardiac center accelerates heartbeat Blood drains from upper body, creating homeostatic imbalance Baroreceptors above heart respond to drop in blood pressure Baroreceptors send signals to cardiac center of brainstem • Self-amplifying cycle – Leads to _____________________ in the same direction – Feedback loop is repeated—change produces more change • Normal way of producing rapid changes – Occurs with childbirth, blood clotting, protein digestion, fever, and generation of nerve signals 3 Brain stimulates pituitary gland to secrete oxytocin 4 Oxytocin stimulates uterine contractions and pushes fetus toward cervix 2 Nerve impulses from cervix transmitted to brain 1 Head of fetus pushes against cervix • • • • • Anatomical position Planes of section Directional terms Regions of the body Body cavities and membranes • • • • • Person stands erect Feet flat on floor Arms at ________ Palms, eyes & face facing ______ Standard frame of reference for anatomical descriptions & dissection • Planes are imaginary flat surfaces passing through the body – sections are anatomical views if body is cut on a plane • ____________ – divides body into right and left halves • ________ – divides body into front & back portions • ___________ – divides the body into upper & lower portions • Sagittal plane divides body into right and left _________ – divides body into equal right and left halves – divides the body into right and left portions • __________ – an infinite number Sagittal Frontal Transverse • • • • • • • • above; (toward the head) - __________ below - Inferior toward the midline - __________ away from the midline - Lateral closer to the origin of a body part - ________ farther from the origin of a body part - Distal toward the body surface - __________ away from the body surface - Deep – more internal • Different meanings for humans and animals – Anterior surface of human is surface of chest & belly • anterior in a four-legged animal is the head end – __________ surface of human is back side • posterior in a four-legged animal is the tail end • • • • belly-side - __________ backside - __________ In humans Anterior is the same as Ventral In humans Posterior is the same as Dorsal Cephalic r. (head) Facial r. (face) Cervical r. (neck) Upper limb: Acromial r. (shoulder) Thoracic r. (chest): Sternal r. Pectoral r. Axillary r. (armpit) Brachial r. (arm) Cubital r. (elbow) Umbilical r. Antebrachial r. (forearm) Abdominal r. Inguinal r. (groin) Carpal r. (wrist) Pubic r.: Mons pubis Palmar r. (palm) External genitalia: Penis Scrotum Testes Lower limb: Coxal r. (hip) Patellar r. (knee) Lower limb: Femoral r. (thigh) Crural r. (leg) Tarsal r. (ankle) Pedal r. (foot): Dorsum Plantar surface (sole) (a) Anterior (ventral) (b) Anterior (ventral) (a) Anterior (ventral) (b) Anterior (ventral) Cranial r. Nuchal r. (back of neck) Interscapular r. Scapular r. Vertebral r. Lumbar r. Sacral r. Gluteal r. (buttock) Dorsum of hand Perineal r. Femoral r. Popliteal r. Crural r. Tarsal r. Calcaneal r. (heel) (c) Posterior (dorsal) (d) Posterior (dorsal) Quadrants Stomach Right upper quadrant Left upper quadrant Right lower quadrant 10th rib Left lower quadrant (a) Anterior superior spine (b) Regions Hypochondriac region Liver Epigastric region Gallbladder 10th rib Subcostal line Lumbar region Large intestine Umbilical region Small intestine Intertubercular line Hypogastric region Inguinal region Urinary bladder Midclavicular line Urethra (c) (d) • Major body cavities – Dorsal body cavity • __________ cavity • __________ canal – Ventral body cavity • thoracic cavity • diaphragm separates them • abdominopelvic cavity – __________ cavity – __________ cavity • Lined by membranes • Filled with __________ • The area between the lungs - ______________ – contains heart, major blood vessels, esophagus, trachea & thymus • __________ cavities hold the lungs • Membranes – visceral and parietal pleura cover lungs & line rib cage – visceral and parietal pericardium cover heart & line pericardial sac • Brim of the pelvis separates abdominal from pelvic cavity contains GI tract, kidneys & ureters contains rectum, bladder, urethra & reproductive organs • Membranes = visceral & parietal __________