Cell Membrane Diseases If the cell membrane is unable to do its job properly, this can cause the cell to stop working properly. If many cells have bad cell membranes, the disease can affect an entire organ or even the whole body. In many of these cell membrane diseases, proteins within the cell membrane don't transport materials properly. It is not necessarily that the membrane itself disappears, rather that certain parts don't work. Choose a disease/disorder from the list below to complete your research project on. You will be completing a poster, model, video or slideshow or format of your choice to display your research. All of the disorders mentioned are either disorders of cell membranes or can be treated using knowledge of cell membranes. Topics of Research Alzheimer's Cystic Fibrosis Polycystic Kidney Disease Stroke Cancer (choose a type) Pain Reduction (Morphine) Diabetes Cholera Major Depressive Disorder Anxiety Disorder Part 1: Disease Background Information What is the disease? (describe its characteristics etc.) What are the symptoms of the disease? What age/group/gender are most affected by this disease Statistics of Disease (how many are affected in Alberta? Canada? Worldwide?) Which specific cells or groups of cells are involved? How is the disease diagnosed? How can this disease be prevented? If not, how can one maintain a level of health? Part 2: Cause of Disease How does a person get the disease/disorder? Make sure to speak to the molecular level. Is there a genetic basis to the inheritance of the disease/disorder? Explain in detail. How does this disease effect the body system? How would the body system function normally? (again, speak at the cellular level) How is the disease related to cell membrane activity/function/involvement? Be detailed. Include a schematic diagram comparing a healthy cell to a cell with your disease/disorder. Part 3: Medical Research What current research is being done to either understand the disorder better or to treat/cure the disorder? Where is it being done? What exactly are they researching and how? o Be sure to identify areas of research at the cellular level (example of DNA and gene mapping, cell membrane function etc.) What kind of technologies are they using for the research? Identify specific careers that would be involved in the research and treatment of the disorder. Part 4: Cure/Treatment Can your disorder be cured? Or only treated? Describe what treatment or curative options there are for your disorder Describe the role of understanding the cell membrane on the use of various medications or treatments for your disorder Describe the pharmacology involved in the treatment method. Identify specifically what particles (molecules, ions, proteins, receptors) are affected at the cellular level.