HUMAN GROWTH AND DEVELOPMENT PRE-EMBRYONIC PERIOD the first 2 weeks of human development after conception. EMBRYONIC PERIOD third week after fertilization and continuing until the end of the eighth week. This period is known as the organogenetic period that denotes the formation and differentiation of organs and organ systems week 2: developing of The yolk sac and the amniotic cavity, and the embryoblast differentiates into the Implantation of the blastocyst is completed by the end of the second week. week 3: differentiation of the three germ layers: 1-ectoderm (outer layer, gives rise to skin, teeth, and glands of the mouth and nervous system) 2-endoderm (inner layer, gives rise to epithelium of the respiratory, digestive and genitourinary tracts) 3-mesoderm (lies between the ectoderm and endoderm; gives rise to the connective tissue) week 8: a clear distinction between the upper and lower limbs, the external genitals are well developed, not well enough to distinguish the gender, and the embryo has a human appearance and main organ systems have also begun to develop THE FETAL PERIOD Weeks 9 to 12: 1-face is recognizably human at 10 weeks 2-Ossification appears 3-intestines leave the umbilical cord and enter the abdomen 4-external genitalia differentiate and are distinguishable by week 12 Weeks 17 to 20: 1-fetal movements (quickening) 2-skin is now covered with a thick, cheese-like material called vernix caseosa 3-hair appears on the eyebrows and head. 4-Subcutaneous deposits of brown fat, used by the newborn for heat production Weeks 21 to 25: By 24 weeks 1-fingernails 2-lungs have begun to secrete surfactant Weeks 26 to 29: fetus may survive if born 1-lungs can breathe air 2-central nervous system can regulate body temperature and direct rhythmic breathing Weeks 30 to 34: At 30 weeks the pupillary light reflex is present. Weeks 35 to 40: At 35 weeks, the fetus has a strong hand grasp reflex and orientation to light