Appendicitis in children Ahmed Said What is Appendicitis? Appendicitis is an infection or inflammation of the appendix, a pinky-sized, tube-like structure part of the large intestine. The appendix is in the right lower section of the abdomen in most children. Appendicitis is the most common cause of emergency abdominal surgery in children. Though it can happen at any age, appendicitis occurs more frequently in school-aged children, and rarely occurs under the age of 1. 12/10/2022 PRESENTATION TITLE 2 What causes Appendicitis in a child? Appendicitis is the result of a blockage of the appendix caused by hard mucus or stool, or swelling caused by a virus. The blockage causes the appendix to swell and become inflamed. If the swelling and infection are left untreated, the appendix can perforate, causing the contents of the appendix to be released into the abdomen, spreading the infection. 12/10/2022 PRESENTATION TITLE 3 Signs of Appendicitis 12/10/2022 1 2 3 4 5 Sudden pain that begins on the right side of the lower abdomen. Sudden pain that begins around belly button and often shifts to your lower right abdomen. Pain that worsens if you cough, walk or make other jarring movements. Nausea and vomiting and diarrhea Fever and Loss of appetite. PRESENTATION TITLE 4 How does a child act with appendicitis? The most common symptoms of appendicitis in children are: Abdominal pain that begins around the belly button and moves to the right lower side of the abdomen. The pain typically increases when walking, jumping or coughing, and usually worsens as time goes on. Constipation and frequent urination. 12/10/2022 PRESENTATION TITLE 5 Stages of appendicitis Early stage appendicitis Obstruction of the appendiceal lumen leads to mucosal edema and ulceration------ The child could experience mild epigastric pain lasts four to six hours. 12/10/2022 PRESENTATION TITLE 6 Stages of appendicitis Suppurative appendicitis Increased intraluminal pressure associated with obstructed lymphatic and venous drainage-----Allows invasion of the appendix wall by bacteria and inflammatory fluid----- Child will typically experience the shift of pain from the umbilical area to the LRQ. 12/10/2022 PRESENTATION TITLE 7 Stages of appendicitis Perforated appendicitis Persisting tissue ischemia results in appendiceal infarction and perforation. Perforation can cause localized or generalized peritonitis. 12/10/2022 PRESENTATION TITLE 8 Stages of appendicitis Spontaneously resolving appendicitis – If the obstruction of the appendiceal lumen is relieved, acute appendicitis may resolve spontaneously. This occurs if the cause of the symptoms is lymphoid hyperplasia or when a fecalith is expelled from the lumen. Treated only with Antibiotics 12/10/2022 PRESENTATION TITLE 9 Diagnostics and Lab Tests Among laboratory tests, IL-6 is the best laboratory marker of acute appendicitis, although it is only of medium diagnostic accuracy. White blood cell count and C-reactive protein concentration in serum are of low diagnostic accuracy and have only a supportive role in diagnosing acute appendicitis in children. 12/10/2022 PRESENTATION TITLE 10 Diagnostics and lab tests abdominal X-ray, an abdominal ultrasound, computerized tomography (CT) scan or magnetic resonance imaging (MRI) 12/10/2022 PRESENTATION TITLE 11 What can be mistaken with Appendix pain? Appendicitis can easily be confused with something else, such as: •gastroenteritis. •severe irritable bowel syndrome (IBS) •constipation. •bladder or urine infections. 12/10/2022 PRESENTATION TITLE 12 Physical Testing for Appendicitis A health care provider tests for the obturator sign by asking the patient to lie down with the right leg bent at the knee. Moving the bent knee left and right requires flexing the obturator muscle and will cause abdominal pain if the appendix is inflamed. 12/10/2022 PRESENTATION TITLE 13 Treatment Some researchers has suggested that appendectomies aren’t necessary to treat uncomplicated appendicitis, which is appendicitis without a ruptured appendix, pus-filled abscesses, or peritonitis. Instead, an antibiotic-only treatment can do the trick. Although, most of the patients treated with Antibiotics only required fewer doses of narcotics, returned to work quicker, and did not have a 12/10/2022 higher perforation rates, thay had recurrent appendicitis in one year. PRESENTATION TITLE 14 Complications after surgery • Abnormal connections between abdominal organs or between these organs and the skin surface (fistula) • Abscess • Blockage of the intestine • Infection inside the abdomen (peritonitis) • Infection of the surgical wound 12/10/2022 PRESENTATION TITLE 15 Thank you Ahmed Said