Essay: 1 X 15 1. Classify pharmacological agents used in the treatment of congestive cardiac failure. Explain the mechanism of action of inotropic drugs in the treatment of cardiac failure. Mention the adverse effects and the uses of these drugs. What are recent advances in the treatment of cardiac failure? Short note: 1. Explain the Cheese reaction and treatment of Hypertensive crisis 2. Importance of beta blockers in angina. 2X5 MCQ: 5X1 1. A 62-year-old patient with a history of asthma and vasospastic angina states that he gets chest pain both with exertion and at rest, about ten times per week. one sublingual nitroglycerin tablet always relieves his symptoms, but this medication gives him an awful headache every time he takes it. Which is the best option for improving his angina? A. Change to sublingual nitroglycerin spray. B. Add amlodipine. C. Add propranolol. D. Replace nitroglycerin with ranolazine Ans: B 2. A 40-year-old female was just started on therapy for hypertension and developed a Dysgeusia which is a loss or altered taste. Which drug is most likely responsible for this side effect? A. Captopril. B. Lisonopril. C. Enalapril. D. Ramipril. Ans : A 3. A hypertensive patient with a renal disease was prescribed clonidine, but stopped it abruptly. Which side effect will he experience? A. Increased renal blood flow. B. decrease glomerular filtration C. Rebound hypertension. D. Severe hypotension. Ans : C 4. An unknown patient presented to the ER unconsciously, blood analysis was done and the result show that the patient has hypokalemia and hypomagnesemia. While the ECG suggests a heart failing. Which of the following drugs is contraindicated in this case? A. Digoxin. B. Spironolactone. C. Isosorbite dinitrate. D. Ramipril. Ans : A 5. Which of the following group of drugs are the 1st line treatment in both hypertension and heart failure? A. ACE inhibitor. B. Diuretics. C. Cardiac glycosides. D. Both A & B. Ans : D