BIOLOGY (Greek Words) bios – “ life “ logus – “ to study “ science of life the study of living things BRIEF HISTORY OF BIOLOGY I. PRIMITIVE PERIOD characterized by uncritical accumulation of information mainly derived from the practical processes or necessities of obtaining materials like the basic needs accumulation of knowledge was not recorded II. CLASSICAL PERIOD began with the Greeks and continued with the Romans it marked by great curiosity about natural phenomena and ability to organize biological knowledge and record it HIPPOCRATES ARISTOTLE THEOPHRASTUS GALEN 1 III. RENAISSANCE PERIOD (14TH to 16TH centuries ) curiosity about living things, its structure and functions were the main concern during this time MICHAEL ANGELO ANDREAS VESALIUS WILLIAM HARVEY LEONARDO da VINCI IV. MODERN ERA (17th century to present) The introduction of microscope at the beginning of the 17th century marked the start of modern biology ANTON VAN LEEUWENHOEK ROBERT HOOKE ROBERT BROWN MATTHIAS JACOB SCHLEIDEN THEODORE SCHWANN CAROLUS LINNAEUS JEAN BAPTISTE LAMARCK CHARLES DARWIN LOUIS PASTEUR GREGOR MENDEL HUGO de VRIES E. H. STARLING ERNST HAECKEL H. E. COWLA V. E. SHELFORD 2 BRANCHES OF BIOLOGY I.ACCORDING TO ASPECT OR METHOD OF STUDY: 1. Anatomy 14. Histology 2. Biogeography 15. Limnology 3. Biochemistry 16. Morphology 4. Biological Earth Science 17. Nomenclature 5. Biological Psychology 18. Ontogeny 6. Biomathematics 19. Organology 7. Biophysics 20. Oceanography 8. Cytology 21. Paleontology 9. Ecology 22. Pathology 10. Embryology 23. Phylogeny 11. Evolution 24. Physiology 12. Endocrinology 25. Systematic Taxonomy 13. Genetics 26. Zoogeography II.ACCORDING TO THE TYPE OF ORGANISMS 1. Bacteriology 10. Mammalogy 2. Botany 11. Microbiology 3. Carcinology 12. Mycology 4. Conchology 13. Ornithology 5. Entomology 14. Parasitology 6. Helminthology 15. Phycology 7. Herpetology 16. Protozoology 8. Ichthyology 17. Virology 9. Malacology 18. Zoology 3 THE NATURE OF LIFE LIFE – is the state of an animal or plant in which its organs are capable of performing their functions CHARACTERISTICS OF LIVING THINGS AND HOW IT DIFFERS FROM NON-LIVING NON-LIVING CHARACTERISTICS LIVING THINGS THINGS 1.ORGANIZATION made up of cells made up of atoms can combine chemical elements for can not their needs recombine materials 2.GROWTH internal growth external (INTUSSUSCEPTION) growth (ACCRETION) 3.LIFE CYCLE definite life cycle no orderly (IRREVERSIBLE) cycle 4.REPRODUCTION can reproduce sexually or asexually can not reproduce 5.FORM/SIZE definite form/size 6.MOVEMENT can move by themselves materials can vary widely can move by external force 4 7.IRRITABILITY disproportionate reaction to changes 8.ADAPTABILITY “autoplastic” “alloplastic” 9.METABOLISM anabolism catabolism vital processes takes place 10.CHEMICAL COMPOSITION made up of organic & no definite chemical inorganic composition 5 proportionate reaction to change can not adapt to changes does not undergo vital processes COMPARISON BETWEEN PLANTS and ANIMALS POINT OF COMPARISON 1.FORM and SRUCTURE 2.METABOLISM ANIMALS PLANTS body form is rather constant organs are mostly internal cells are within delicate membrane growth is usually differential mostly with melanin pigment body form is often variable “Heterotrophs” (major consumer) undergo cellular respiration end products are CO2,H2O & urea “Autotrophs” (major producer) 6 organs are added externally cells are within thick rigid cell walls growth is usually terminal mostly with chlorophyll pigment undergo photosynthesis O2 is released as by product 3.IRRITABILITY with nervous system can respond faster to stimuli without nervous system respond slower to stimuli THE NATURE OF LIFE: THEORIES ON THE ORIGIN OF LIFE 1. Divine Creation Theory 2. Biogenesis 3. Abiogenesis or Spontaneous Generation 4. Cozmozoic or Interplanetary 5. Naturalistic Theory 6. Philosophical Theory of Eternity 7. Big Bang Theory and Chemical Evolution 8. Coacervate Theory 7 CHEMICAL BASIS OF LIFE PROTOPLASM – the living part of the cell which is composed of complex mixture of inorganic and organic compounds. MATTER – anything that occupies space and has mass I. PHYSICAL PROPERTIES OF MATTER Example: odor color taste transparency physical states density boiling point freezing point melting point STATES OF MATTER 1. Gases 3. Solids 2. Liquids 4. Plasma 8 II. CHEMICAL PROPERTIES Substance undergoes change in composition Example: rusting (shiny bright metal) reddish brown cooking egg (colorless albumin) change to white ATOMS basic building block of matter smallest particle/unit of an element composed of protons (+) neutrons (neutral) electrons (-) MOLECULES – smallest particle of a compound/ element consisting of two or more atoms ELEMENTS simplest form of a substance that can not be decomposed by simple chemical means possess either positive or negative charge classified into metals, non metals & metalloids COMPOUNDS substances whose molecules are made up of two or more kinds of atoms classified into organic & inorganic 9 CHEMICAL BONDING interactions involving atoms of elements combining with one another classified into covalent bond, ionic bond & hydrogen bond I.COMPOUNDS: A. Organic – contain carbon atoms in their molecules FOUR IMPORTANT ORGANIC COMPOUNDS IN THE ORGANISMS BODY 1. CARBOHYDRATES – simplest and most abundant; main source of energy in the body THREE CLASSES OF CARBOHYDRATES 1. starches 2. cellulose 3. sugars a. MONOSACCHRIDES/SIMPLE SUGARS Example: glucose (dextrose or blood sugar) fructose (fruit sugar) galactose (milk sugar) mannose molecular formula – C6H12O6 10 b. DISACCHARIDES/DOUBLE SUGARS Example: sucrose (table sugar) lactose (milk sugar) maltose (malt sugar) molecular formula – C12H22O11 c. POLYSACCHARIDES/COMPLEX SUGARS Example: starches (energy storage in plant) glycogen (animal starch) cellulose (structural materials in plants) 2. PROTEINS – the most important organic compounds AMINO ACIDS building blocks of proteins important for growth and repair of tissues act as enzymes, hormones, antigens and antibodies THREE TYPES OF PROTEINS 1. fibrous protein – keratin and silk 2. globular protein – hemoglobin 11 3. conjugated protein – nucleoprotein ( histones ), glycoprotein (mucin), lipoprotein (serum & brain tissue), chromoprotein (cytochrome) 3. NUCLEIC ACIDS the large and the most complex organic molecules important for protein synthesis and heredity POLYPEPTIDES – are the building blocks of nucleic acids TWO KINDS OF NUCLEIC ACIDS 1. DNA (deoxyribonucleic acid) found inside the nucleus of cell 2. RNA (ribonucleic acid) found both inside and outside the nucleus of the cell 4. LIPIDS are fats and other related substances insoluble in water soluble only in chloroform and acetone GLYCEROL and FATTY ACIDS are the building blocks of lipids important in the storage of energy and component of the cell membrane 12 TYPES OF LIPIDS a. Simple Lipids – oils, fats, waxes b. Compound/Complex lipids – steroids, cholesterol and phospholipids B. Inorganic Molecules usually do not have carbon atoms often associated with non living things THE MOST COMMON INORGANIC MOLECULES FOUND IN AN ORGANISMS BODY 1. WATER most abundant component of the protoplasm (60 – 90%) universal solvent retain heat well high surface tension 2. GASES (oxygen and carbon dioxide) importance in the organism’s body a. respiratory gases b. in tissue fluids (blood & lymph) c. in oxidation of food molecules in order to release energy 3. MINERALS 4. ORGANIC SALTS present in the bone, teeth and shells 13 Examples: calcium carbonate - CaCO3 calcium phosphate - ( Ca3( PO 4 ) 2 ) sodium chloride - NaCl Important in Vital Processes such as: a. irritability of muscles and nerves b. growth and repair of tissues c. act as buffers or regulators of acid-base balance VITAMINS Inorganic compounds usually of plant origin Accessory food factors needed by man and animals for normal growth and development BASIC FOOD GROUPS: The Basic Seven Food Groups Based on their Nutrient Contents GROUP I - meat, poultry, fish, eggs, dried beans, peas and nuts GROUP II - green and yellow leafy vegetables GROUP III- citrus fruits, raw cabbage, salads greens and tomatoes 14 GROUP IV- potatoes, other vegetables and non-citrus fruits GROUP V - bread, breakfast cereals, flour biscuits and crackers GROUP VI - butter and fortified margarine GROUP VII- milk and milk products 15 THE CELLULAR BASIS OF LIFE CELL (CYTOLOGY) the basic structural and functional unit of all living things varies in shape and size BRIEF HISTORY OF CELL BIOLOGY 1. ROBERT HOOKE (1665) - cells 2. ANTON VAN LEEWENHOEK (1674) - protozoan, red blood cells, capillary system 3. ROBERT BROWN (1833) - nucleus 4. DUJARDIN (1835) - protoplasm 5. MATTHIAS SCHLEIDEN (1838) 6. THEODOR SCHWANN (1839) - all living things are composed of cells 7. RUDOLF VIRCHOW (1858) - all cells come from pre-existing cells CELL THEORY 1. All organisms are made up of cells and a cell is the structural and functional unit of organisms. 2. Cells are capable of self-reproduction and cells come only from pre-existing cells. 16 TYPES OF CELLS PROKARYOTIC CELLS EUKARYOTIC CELLS cells without true nucleus cells with true nucleus cell size ranging from 1 to ranging from 10-100um 10 um in linear dimension outer boundary is composed of plasma composed of cell wall & membrane made up of plasma membrane phospholipids bilayer of proteins no membrane bounded with membrane nucleus nucleus (not distinct)with composed of multiple nucleoid containing single chromatin chromosome(DNA only) cytoplasm contains few contains many organelles organelles like ribosomes, thyllakoids, enzymes undergo aerobic & aerobic respiration only anaerobic respiration divide by binary fission by mitosis/meiosis mostly unicellular mostly multicellular ex.bacteria, cyanobacteria ex. Animals, plants, protest, or blue green algae fungi 17 MORPHOLOGY and PHYSIOLOGY OF EUKARYOTIC CELL STRUCTURES CHARACTERISTICS FUNCTIONS 1.Cell Membrane/ outermost membrane give strength, Plasma of the cell shape and Membrane protection to the cell with cilia, flagella microvilli pinocytic vesicles 2.Protoplasm triple layered composed of protein & lipids 3.Nucleus consist of: the most distinct structure located at the center of the cell the control center of the cell important in cellular reproduction a. nuclear membrane encloses the nucleus protects and regulates the regulates traffic flow of materials jelly-like living exhibit the substance of the cell properties comprising the and activities nucleus & cytoplasm of life 18 passage of materials b. nucleoplasm the cytoplasm inside the nucleus chromosomes and nucleoli are suspended on it c. chromosomes thread like bodies that bear the genes important in heredity d. nucleolus dark staining bodies inside the nucleus for protein synthesis 4.Cytoplasm the protoplasm outside the nucleus contains organelles and inclusions serve to carry out the direction of the nucleus ORGANELLES permanent, subcellular structure in the cytoplasm performed the different metabolic activities of the cell A. Endoplasmic Reticulum routes of system of membrane 19 enclosed canals forming network in the cytoplasm TYPES: Smooth ER Rough ER b.Ribosomes transport for the different materials within the cells without ribosomes with ribosomes for protein spherical bodies synthesis aggregates of protein and RNA C.Golgi Complex system of membrane secretes chemical enclosed vesicles products, membrane repair, transport of materials, packaging secretory products D. Mitochondria rounded cylinders or powerhouse of the cell globules E. Lysosomes act as the contains powerful “suicide bag of digestive hydrolytic enzymes the cell” system of the cell F. Plastids gives color to mostly found in 20 plants colored substances within the cells KINDS: chromoplast leucoplast G.Centrosomes H.Vacuoles KINDS: food vacuoles water vacuoles colored plastids contained chlorophyll(green) colorless plastids or white small dark bodies located above the nucleus contains one or two centrioles membrane enclosed cavities filled with fluid or granular materials 21 the organisms contained pigments and other materials play a role in spindle formation during cell division for the storage of food and water DIFFERENCES BETWEEN PLANT and ANIMAL CELL PLANT CELL bounded by cell wall and plasma membrane, containing cellulose and other compounds contained plastids lack lysosomes have large vacuoles for the storage of H2O undergo photosynthesis ANIMAL CELL bounded by plasma membrane only, no cell wall lack plastids contained lysosomes small vacuoles for the storage of food undergo digestion 22 CELLULAR REPRODUCTION / CELL DIVISION process exhibit by all living organisms as they grow or increase in size and number of the cell TYPES: 1. MITOSIS (duplication division ) process that produces two daughter cells with the same quantity and quality of chromosomes as the parent cell (diploid) involve the division of… nucleus (karyokinesis) cytoplasm (cytokinesis) occur in the somatic cell (body cells) of eukaryotic organism 2. AMITOSIS (direct cell division) process of division but there is no evidence of mitotic changes the nucleus and cytoplasm simply divide unequally or roughly equal without undergoing the phases of mitosis cells do not function normally occur in prokaryotic organism or in degenerating cells under pathological conditions 23 3. MEIOSIS (reduction division) process that produces four daughter cells with haploid no. of chromosomes as the parent cell involves two successive divisions mitosis 1 and meiosis 2 occur in sex cells (egg and sperms) CELL CYCLE: the cyclical process of growth and mitosis consists of 4 phases, the 3 stages of interphase (G1, S and G2)) and the mitotic phase INTERPHASE the preparatory stage for the cell to undergo mitosis consists of 3 subdivisions , the G1 period (pre synthesis interphase) S period (synthesis phase) G2 period (post synthesis interphase) MITOTIC PHASE (consists of 4 phases) 1. PROPHASE the stage of preparation the chromosomes appear much shorter but thicker and start to coil tightly centrioles become visible and move to the opposite poles of the nucleus 24 nucleolus no longer visible nuclear membrane start to disappear mitotic apparatus formed (asters, spindles fibers) 2. METAPHASE the stage of separation chromosomes migrate and align at the equatorial plane (center) centromeres of each chromosomes are attached to the spindle fibers 3. ANAPHASE the stage of migration centromeres of each chromosomes divide or split each chromatid of a double stranded chromosome separates from its sister chromatid and goes to the opposite poles cytokinesis begins (formation of cell plate in the plant cell and cleavage furrow in animal cell) 4. TELOPHASE stage of nuclear reconstruction two sets of chromatids reached the opposite poles chromosomes start to uncoil, becomes longer, thinner and less distinct nuclear membrane starts to reappear enclosing each of chromosomes 25 nucleolus also reappear while mitotic apparatus disappear cytokinesis completed resulting into two daughter cells with the same quantity and quality of chromosomes as the parent cell 26 TISSUES composed of cells with similar structures and functions PLANT TISSUES I. MERISTEMATIC TISSUE cells capable of active cell division (mitosis) A. TERMINAL / APICAL MERISTEMS located at the tips of roots and stems responsible for the increase in length of the plant B. INTERCALARY MERISTEMS portion of the apical meristems separated from the apex during development lie below the node and the base of stem of grasses C. LATERAL MERISTEMS located in the periphery of the roots and stems responsible for the increase in the diameter of the organ II. PERMANENT TISSUE composed of mature, differentiated cells 27 A. SURFACE TISSUE form the protective outer covering of the plant Example: Epidermis short – lived in many plants replaced by periderm tissue when the plants grow or becomes matured (outer bark of old trees) B. FUNDAMENTAL TISSUE simple tissues composed of a single type cell form the bulk of the softer parts of plants responsible for storage, basic metabolism and support TYPES: 1. PARENCHYMA (most abundant plant tissue) cells usually have thin primary walls, no secondary walls with large vacuoles chlorenchyma – parenchyma with chloroplast function for photosynthesis aerenchyma – parenchyma with intercellular spaces to improve gas exchange both found in leaves, also in stems and roots 2. COLLENCHYMA composed of elongated cells cell walls are irregularly thickened 28 important supporting tissue in young plants, in the stem of non-woody older plants and in leaves (petiole) 3. SCLERENCHYMA composed of rigid cells, uniformly thick with heavily lignified secondary walls occur in all mature parts of the plants support the non-extending regions of plants TYPES: SCLEREIDS- short cells with variable shapes FIBERS- long, slender cells 4. ENDODERMIS a layer surrounding the vascular tissue core of roots and stems appear like elongated parenchyma cells with lignified and suberized band called “casparian strip” C. VASCULAR TISSUE / CONDUCTIVE TISSUE Composed of several kinds of cells that differ in structure and in function Specialized for long distance transport of water and dissolved solutes (nutrients) 29 TYPES: 1. XYLEM Responsible for the transport of water and dissolved substances upward in the plant body 2. PHLOEM Responsible for the transport of food / nutrients both up and down in the plant body 30 ANIMAL TISSUES I. EPITHELIAL TISSUE covering of external surface or lining of all free body surfaces (internal) forms continuous layer of compactly arranged cells Functions: mainly for covering and protection TYPES AS TO SHAPE OF THE CELLS: 1. SQUAMOUS EPITHELIUM made up of thin, flat cells that resemble blocks Location: outermost layer of the skin, lining of mouth, esophagus 2. CUBOIDAL EPITHELIUM cube shaped cells in appearance Location: lining of ducts, thyroid gland and kidney tubules 3. COLUMNAR EPITHELIUM rectangular shaped cells Location: lining of the trachea, stomach, small Intestine 4. CILIATED/ FLAGELLATED EPITHELIUM maybe columnar or cuboidal cells w/c are provided with cilia or flagellum Location: innermost lining of the trachea, intestine, spermducts oviduct 31 TYPES AS TO STRUCTURE/NO. OF CELLS 1. SIMPLE EPITHELIAL TISSUE one layer of cells 2. STRATIFIED EPITHELIAL TISSUE two or more layers 3. PSEUDOSTRATIFIED EPITHELIAL TISSUE all cells are in contact with the basement membrane but not all reach the surface AS TO FUNCTION: 1. GLANDULAR EPITHELIAL TISSUE for secretion 2. SENSORY EPITHELIAL TISSUE for reception of stimuli and transmission of impulses 3. GERMINAL EPITHEIAL TISSUE for reproduction 4. PROTECTIVE EPITHELIAL TISSUE for protection, covering II. CONNECTIVE TISSUE/ SUPPORTIVE cells are far apart, very variable embedded in intercellular matrix (liquid, semi-solid, solid) contains large amount of cementing substance between cells 32 Functions: binds structure together connects many body parts fill spaces, store fats and forms blood cell provides support and protection Types as to Arrangement of Fibers in the Matrix: 1. Loose connective tissue loose arrangement of fibers in the matrix cells (fibroblasts) are farther apart separated by jelly-like matrix with white collagen fibers (for flexibility and strength) and yellow elastic fibers (for elasticity) lies beneath the epithelium of the skin and most of the internal organs a. mesenchyme b. mucous connective tissue c. reticular connective tissue d. areolar connective tissue e. adipose connective tissue 2. Dense (fibrous) connective tissue contains many collagen fibers that are packed closely together more specific functions in vertebrates than loose connective tissue 33 with less amorphous ground substance a. irregular arranged dense connective tissue b. regular arranged dense connective tissue 3. Specialized connective tissue a. cartilages skeleton during embryonic stage; composed of cells (chondrocytes) located in small spaces called “lacunae with collagenous or elastic fibers” Types as to appearance of the matrix: hyaline cartilage elastic cartilage fibrocartilage b. bones or osseous tissues rigid form of connective tissue comprises most of the skeleton in higher vertebrates composed of cells (osteocytes) located in small cavities (lacunae) of calcified matrix radiating from each lacuna are narrow channels (canaliculi) which penetrate adjacent canaliculi of neighboring lacunae forming lamellar structure c. hemopoietic tissue formation and maturation of blood cells 34 d. blood composed of blood cells (erythrocytes, leukocytes, and thrombocytes) and a fluid intercellular substance (plasma) III. MUSCULAR TISSUE cells are usually elongated and are bound together into sheets or bundle by connective tissue muscle cells have greater capacity for contraction than most other cells responsible for most movement in higher animals TYPES AS TO STRUCTURE/ FUNCTION: a. Skeletal/ Striated Muscle composed of long, cylindrical filamentous cell found attached to the skeleton responsible for voluntary movement of the body b. Cardiac/ Striated Muscle composed of linear, branching bundles of fibers joined end to end by intercalated disc found in the walls of the heart responsible for the involuntary contraction of the organ c. Smooth/ Unstriated Muscle also called visceral muscle composed of elongated cells with tapered ends 35 spindle shaped or fusiform found in the internal organs (stomach,intestine) responsible for the involuntary movement of these organs IV. NERVOUS TISSUE composed of nerve cells or neurons has great capacity to respond to stimuli since they can be easily stimulated and can transmit impulses rapidly NEURONS Made up of cell body ( perikaryon ) and one or more protoplasmic processes (axon and dendrites) Do not undergo cell division Responsible for reception of stimuli and transmission of impulses 36 THE PLANT AS AN ORGANISM The plant is a diverse group of organisms. Its members range from simple unicellular and multicellular algae to highly developed vascular plants. It is divided into categories based upon the structure and reproduction methods. Of all the members of the plant kingdom, the vascular plants show the greatest internal specialization into tissues and organs. It is considered as the dominant plant group on land today. MAJOR GROUPS OF VASCULAR PLANTS: 1. SPORE – BEARING those that produces spore instead of seed an asexual reproductive cell that develops into a new plant Example: ferns, club mosses, horse tails 2. GYMNOSPERMS group of seed producing plants in which the seeds are naked or not protected by a case, “ovary wall” it may or may not produce CONES a fruiting structure composed of modified leaves or branches 37 Example: CYCADS – look like a short palm tree GINKGOS – large tree with fan shaped leaves CONIFERS or CONE BEARERS – pine tree, junifers, red wood 3. ANGIOSPERMS (flowering plants) the largest group among vascular plants group of seed producing plants in which the seeds are enclosed or protected by an ovary wall (fruits) its unique and outstanding structure is the FLOWER Example: all the crop plants in orchards, garden and fields from tiny herbs, shrubs to trees TWO MAJOR SUBCLASSES: A. MONOCOTYLEDONS (monocot) Example: grasses, rice, corn, lilies, orchids and other grass like plants B. DICOTYLEDONS (dicot) Example: roses, sunflowers, citrus plants, maple trees And other great variety of plants 38 STRUCTURAL DIFFERENCES BETWEEN THE TWO MORPHOLOGICAL MONOCOT STRUCTURE 1. Cotyledons/Embryo 1 cotyledon trimerous 2. Flowers/Petals MULTIPLE OF 3’s 3. Leaves/Venation Parallel- Veined 4. Roots Fibrous/Diffuse 5. Stem Anatomy Scattered Vascular Bundles Numerous Without Vascular Cambium DICOT 2 cotyledons pentamerous MULTIPLE OF 5’s Net – Veined Tap Root Vascualr Bundles in Rings Few With vascular Cambium TYPICAL ORGANS OF FLOWERING PLANTS: A. VEGETATIVE ORGANS – root, stem, leaves for growth, development and maintenance of life B. REPRODUCTIVE ORGANS – flowers, fruit, seeds concerned with sexual reproduction and production of seeds 39 ORGANS composed of several tissues grouped together into structural and functional unit PLANT ORGANS I. SHOOT SYSTEM – visible structure above the ground portion (aerial) A. STEM ascending axis of the plant on which the leaves and buds are attached consist of nodes and internodes Function: for support, conduction, and storage of food and water substances TYPES OF STEM: HERBACEOUS WOODY – B. LEAVES lateral outgrowth of the stem usually flat, thin, expanded and green in color cutinized and with chlorophyll Function: site for the process of PHOTOSYNTHESIS, RESPIRATION and TRANSPIRATION 40 TYPES OF LEAVES: SEED LEAF FOLIAGE LEAF C. FLOWERS reproductive organ of the plant usually with colored petals and contain pigments male germ cell from the STAMEN unite with the female germ cell from PISTIL, an embryo is formed. Function: concerned with the production of seeds and fruits D. FRUITS matured or ripened ovary of the flower contain the seeds which carry the embryo Function: help in the dispersal of seeds to distant places; hold and protect the seeds E. SEEDS fertilized and developed ovules contain the embryo Function: responsible for the development of new species II. ROOT SYSTEM – structure beneath the ground portion, usually subterranean, no chlorophyll and uncutinized Function: root for ANCHORAGE and ABSORPTION of food and water substances 41 TYPES OF ROOT: TAP ROOT FIBROUS/DIFFUSE ADVENTITIOUS ORGANS 1. ROOT 2. STEM 3. LEAVES 4. FLOWER 5. FRUITS 6. SEEDS STRUCTURES/PARTS primary root, secondary root nodes, internodes, lenticles, buds, leaf scar blades/lamina (margin, midrib veins)petiole, stipule stamen (anther, filament) pistil (stigma, style, ovary) petals, sepals, peduncle, receptacle pericarp (exocarp, messocarp, endocarp) placenta, locule, seeds seed coat (testa, tegmen) cotyledon 42 ANIMAL ORGANS 1. SKIN (INTEGUMENT) - outermost covering of the body surface Function: protection sensation respiration absorption regulation of body temperature 2. STOMACH – the largest and highly muscular part of the digestive tube Function: temporary storage of food partial digestion of food 3. SMALL INTESTINE – the longest and most coiled part of the digestive tube Function: site of final/complete digestion and absorption of food 4. HEART – highly muscular pumping organ of the body Function: pumps blood to all parts of the body 43 5. BLOOD VESSELS – closed tube that serves for the passageway of blood Function: for the passageway of blood (artery, vein, capillary) 6. LUNGS – spongy paired organs Function: for gaseous exchange/respiration 7. KIDNEYS – paired bean shaped excretory organs of the body Function: eliminates nitrogenous wastes of the body by filtering the blood 8. LIVER – the largest gland in the body Function: secretes bile (emulsifier of fats) 9. REPRODUCTIVE ORGANS A. OVARIES – female sex organs that produces and secretes egg cells (ova) and hormones (estrogen, progesterone) B. TESTES – male sex organ that produces or secretes sperm cells and male hormones (testosterone) 44 10. BRAIN – most specialized organ of the body located in the cranial cavity of the skull (master organ) Function: the coordinator and the director of conscious and unconscious activities (center of communications) 45 ORGAN SYSTEM group of organs that work together in the performance of a specific function THE TEN ORGAN SYSTEMS OF VERTEBRATE ANIMALS and THEIR PRINCIPAL FUNCTIONS 1. INTEGUMENTARY SYSTEM body covering and protection from the environment 2. MUSCULAR SYSTEM movement and locomotion 3. SKELETAL SYSTEM support and framework of the body 4. DIGESTIVE SYSTEM converting insoluble food to soluble or absorbable forms; egestion of wastes 5. RESPIRATORY SYSTEM exchange of gases (carbon dioxide and oxygen) 6. CIRCULATORY SYSTEM transportation of different materials or substances 7. REPRODUCTIVE SYSTEM production of new individuals of the same kind 8. EXCRETORY SYSTEM elimination/disposal of nitrogenous wastes of metabolism 46 9. NERVOUS SYSTEM reception of stimuli; transmission of impulses and coordination of functions 10. ENDOCRINE SYSTEM regulation of internal processes and adjustment to external environment 47 INTEGUMENTARY SYSTEM Functions: covering and protection secretions of substances excretion of metabolic wastes sensation respiration regulation of temperature storage of reserve food nourishment for the young THE SKIN (INTEGUMENT) largest organ of the vertebrate’s body covers the surface of the body consists of three layers; (1) outer epidermis (2) inner dermis (3) subcutaneous layer LAYERS OF THE SKIN: 1. EPIDERMIS (outer, thinner) made up of stratified squamous layer of epithelial tissue a layer of dead cells that usually shed as thin flakes (keratinized) composed of “melanin” pigments with epidermal derivatives/structures like hair, nail, claw, hoof, horn, antler divided into five specific layers (mammals) 48 a. stratum corneum b. stratum lucidum c. stratum granulosum d. stratum spinosum e. stratum germinativum 2. DERMIS (inner, thicker) made up of fibrous connective tissue containing collagen and elastic fibers contains muscle fibers, glands, pigment cells, blood vessels, hair follicle and sensory nerves provides structural support for the epidermis and act as matrix for many nerve endings, muscles and specialized cells consists of two regions a. papillary regions b. reticular regions SKIN GLANDS: A. SWEAT GLANDS give off small amount of liquid waste matter B.OIL GLANDS OR SEBACEOUS GLANDS give off oily substances that make the hair smooth and glossy (sebum) prevents the skin from dryness C. MUCOUS GLAND give off slippery substance due to mucin 49 3. SUBCUTANEOUS LAYER (innermost) composed of fat – rich cells (adipose tissue) that serves for the storage of fats act as shock absorbers provides insulation to conserve body heat COMMON SKIN DISORDERS: acne eczema tinea flave (an-an) prickly heat (bungang araw) sunburn athlete’s foot boil contact dermatitis scabies 50 SKELETAL SYSTEM Functions: support the body attachment of muscles protection of internal organs act as levers for locomotion production of blood cells give stability and shape to the body/frame work stores the elements sodium, calcium, and potassium, then releases to the blood holds the reserves protein that the body uses during fasting SKELETON the framework of the animals body composed of cartilage, bone or a combination of both CARTILAGE – white, soft, rubbery tissues BONE – opaque, hard, compact tissues TYPES OF SKELETON: I. AS TO FORMATION MEMBRANE OR DERMAL BONE Formed by direct OSSIFICATION (bone) ENDOCHONDRAL OR CARTILAGE BONE Formed by replacement of pre – existing cartilage into a bone CHONDRIFICATION OSSIFICATION 51 II. AS TO KIND OF BONE TISSUE spongy bone compact bone III. AS TO LOCATION EXOSKELETON or Dermal Skeleton build up outside the body formed from a secretion called CHITIN Example: Arthropods ENDOSKELETON build up inside the body surrounded by soft tissue divided into AXIAL and APPENDICULAR skeletons Example: vertebrates AXIAL REGION – forms the main axis of the body composed of the vertebral column, ribs, sternum and skull 1. VERTEBRAL COLUMN/ BACKBONE (26) the main axial support of vertebrates a chain of bones that runs down the middle of your back protects the SPINAL CORD 2. RIBS (12 Pairs or 24) series of cartilaginous or elongated bony structures attached to the vertebrae forms the THORACIC CAGE involved in breathing protects the heart and lungs 52 Types of Ribs a. TRUE RIBS – the first 7 pairs b. FALSE RIBS – the next 3 pairs c. FLOATING RIBS – the last 2 pairs 3. STERNUM / BREAST BONE (1) flat narrow structure that serve as ventral attachment of the ribs in mammals strengthen the anterior part of the trunk 4. SKULL (29) the framework of the head includes the bones of the cranium (brain box), sense capsule (nose, ear, eye) and visceral arches (jaw, hyoid, larynx) encloses and protects the brain as well as the sense organs APPENDICULAR REGION – endoskeletal structures which are located laterally or at the side of the body composed of the pectoral girdle (shoulder), pelvic girdle (hip), bones of the forelimbs or (arm), and the bones of the hind limbs or (legs) 53 UPPER EXTREMITIES: (64) 1. PECTORAL GIRDLE 2. FORELIMBS - scapula - humerus - coracoid - radius & ulna - clavicle - carpals - metacarpals - phalanges LOWER EXTREMITIES: (62) 3. PELVIC GIRDLE 4. HINDLIMBS - ilium - femur - ischium - tibia & fibula - pubis - patella - tarsals - metatarsals - phalanges Distribution of Bones in Human: New Born Baby - 350 bones Adult Human - 206 bones I. AXIAL REGION – 80 bones cranium ………….8 face………………14 ears……………….6 hyoid……………...1 sternum…………...1 vertebral column…26 ribs………………24 54 II. APPENDICULAR REGION – 126 bones pectoral girdle and forelimbs………………64 pelvic girdle and hindlimbs………………..62 JOINTS – (SYNDESMOLOGY) articulations between cartilages or bones LIGAMENTS – connective tissue that connects bone to bone GENERAL TYPES OF JOINTS: 1. SYNARTHROSES – are immovable joints Example: sutures of the skull 2. AMPHIARTHROSES – slightly movable joints Example: intervertebral disk (in between vertebrae – sacrum & ilium) 3. DIARTHROSES – freely movable joints - most common joints in the body TYPES: a. Gliding Joint / Arthrodia ex. wrist, ankle b. Hinge Joint / Ginglymus ex. elbow, knee c. Ball and Socket / Enarthrosis ex. shoulder, hips d. Pivot Joint / Diarthroses Rotatoria ex. joint between the atlas and axis of the vertebral column (neck) 55 COMMON DISORDERS OF THE BONE: dislocation sprain fracture rickets osteoporosis scoliosis bursitis 56 MUSCULAR SYSTEM (MYOLOGY) Functions: for movement ad locomotion give shape and form to the body produce heat for the body (thermoregulation) MUSCLE STRUCTURES: 1. Muscle cells are long, elongated, slender structure called MUSCLE FIBERS which are covered by a delicate membrane called SARCOLEMMA. 2. Each muscle fiber is subdivided into smaller cylinders called MYOFIBRILS. 3. The myofibril is composed of SARCOMERES attached end to end. 4. Within each sarcomere are alternating thin and thick myofilaments of ACTIN and MYOSIN proteins. 5. The entire muscles are surrounded by an external connective tissue wrapping called the EPIMYSIUM or FASCIA. 6. Each muscle bundle is further enclosed by a connective tissue layer called the PERIMYSIUM. 7. Four or more muscle fibers are in turn enclosed the ENDOMYSIUM. MUSCLES ARE ATTACHED TO THE BONES BY A TOUGH FLEXIBLE TISSUE CALLED TENDONS 57 TYPES OF MUSCLES: (AS TO STRUCTURE) BASIS OF SKELETAL SMOOTH CARDIAC COMPARISON MUSCLE MUSCLE MUSCLE 1.Location attached to wall of the walls of the the skeleton stomach & heart intestine 2. Shape of the elongated or spindle elongated fibers filamentous shaped or fibers that fusiform branch striated unstriated striated 3. Number of many per one per one per nuclei muscle cell muscle or muscle cell or uninucleated but appears multinucleat to be many ed 4. Position of peripheral central central nuclei present absent present 5. Cross (dark & striations light)alterati on most rapid slowest intermediat 6. Speed of e contraction voluntary involuntary involuntary 7. Type of - controlled by - cannot be - controlled nervous control the will controlled by the will 58 AS TO ACTION: Agonist or prime mover – principal mover for specific action. 1. Antagonist – for opposite movement 2. Synergist – helps to stabilize movement of one joint 3. Fixator – fixes the position of the limb when the movement is occurring AS TO SPECIFIC FUNCTION: 1. FLEXORS 7. ELEVATORS/ LEVATORS 8. DEPRESSORS 9. CONSTRICTORS 10.DILATORS 11.SPHINCTERS 2. EXTENSORS 3. ADDUCTORS 4. ABDUCTORS 5. PRONATORS HOW THE MUSCLE WORKS: Skeletal muscles must be stimulated by nerves to operate. Smooth muscles must be stimulated by hormones and a special set of nerves that belong to the autonomic nervous system According to the SLIDING FILAMENT THEORY, muscle cells are made up of long parallel chains of protein molecules that can slide over each other. If the muscle cell 59 is stimulated, the molecular chains slide over one another and the cell contracts. All muscle fibers produce wastes called LACTIC ACID as they work. If a muscle work very hard, these wastes collect in the muscle and lead to MUSCLE FATIGUE or inability of the muscles to contract due to accumulation of lactic acid and the depleton of ATP. COMMON DISORDERS OF MUSCLE: RHEUMATISM ARTHRITIS GOUT MUSCLE CRAMPS MUSCULAR ATROPHY MUSCLE BRUISE 60 DIGESTIVE SYSTEM Functions: ingestion of food digestion or breaking down of complex substances (food) into simple forms (nutrient) absorption of digested food egestion or excretion of undigested food TYPES OF DIGESTION: As to Action 1. Mechanical Digestion – food is converted into small pieces by physical means such as mastication by teeth 2. Chemical Digestion – food is converted into simpler forms by the action of enzymes As to Location 1. Intracellular – digestion takes place within the cell particularly in the lysosomes Example: unicellular organisms – amoeba, paramecium 2. Intercellular or Extracellular – digestion takes place Outside the cell; inside the digestive tube Example: multicellular organisms/ vertebrates 61 COMPOSITION OF EXTRACELLULAR DIGESTION 1. Digestive Tube/ Alimentary Canal start from the MOUTH and end in ANUS 2. Digestive Glands organs that secrete juices containing enzymes for the digestion of food 3. Accessory Parts includes structures that help in the digestion of food Example: tongue and teeth THE DIGESTIVE TUBE: 1. ORAL/ BUCCAL CAVITY (mouth) a. Teeth – used for mastification of food External parts: crown root neck Internal parts: enamel dentine pulp cavity cementum TYPES AS TO STRUCTURE/FUNCTION incisors canines 62 premolars molars TYPES AS TO APPEARANCE primary / milk teeth (20) permanent teeth (32) b. Tongue – for tasting, manipulation, aid in swallowing the food c. Oral Glands – secrete mucus/ saliva for the lubrication of food d. Palate – roof of the mouth 2. PHARYNX/ THROAT common passageway of food and air 3. ESOPHAGUS pathway for the passageway of food exhibit peristalsis movement 4. STOMACH the largest and highly muscular part of the digestive tube (pouch-like) lined with numerous folds called RUGAE maximum capacity 2.5 pints or more food can stays for about 3-5 hours function for temporary storage and partial digestion of food “CHYME” thick semi fluid mass 63 The parts or division of stomach : a. cardiac sphincter (anterior opening) b. fundus (body) c. pyloric sphincter (posterior end) 5. SMALL INTESTINE the longest and most coiled part lined with numerous folds called VILLI about 22 ft. long and food stays around 4-5 hrs. function for final digestion and absorption of food The parts/ divisions of small intestine: a. duodenum – anterior b. jejunum – middle c. ileum – posterior end 6. LARGE INTESTINE posterior part of the digestive tube joined to the small intestine by the ileocolic junction (VERMIFORM APPENDIX) food stays for about 5 to 25 hrs. or more function for the temporary storage of undigested food and further absorption of water and minerals before the waste materials are excreted The parts/divisions are: a. caecum – anterior 64 b. colon – middle part divided into ascending colon, transverse colon and descending colon c. rectum – posterior 7. ANUS posterior opening of the digestive tube exit of fecal matter regulated by anal sphincter muscle THE DIGESTIVE GLANDS: 1. SALIVARY GLANDS Secrete saliva for lubrication of food found in the oral cavity Types: a. parotid – saliva with PTYALIN enzymes b. submaxillary c. sublingual 2. MUCUOS GLANDS secrete mucin for lubrication of food found in oral cavity, esophagus, small and large intestines 3. GASTRIC GLANDS secrete gastric juice found in the rugae of stomach composition of gastric juice are… a. mucin d. lipase b. HCL e. rennin c. pepsin 65 4. INTESTINAL GLANDS secrete intestinal juice found in the VILLI of small intestine composed of enzymes a. mucin e. sucrase b. trypsin f. maltase c. amylase g. lactase d. lipase 5. PANCREAS secrete pancreatic juice that contains… a. amylase b. lipase c. trypsin 6. LIVER largest gland of the body that secretes BILE which is stored in the GALL BLADDER BILE – emulsifies fat into fat globules Other functions: detoxify nitrogenous wastes production of FIBRINOGEN center for fat and carbohydrate metabolism COMMON DISORDERS/ DISEASES: 1. peptic/ gastric ulcer 5. appendicitis 2. indigestion 6. mumps 3. constipation 7. tooth decay 4. diarrhea 66 CIRCULATORY SYSTEM Functions: transport the oxygen and carbon dioxide, soluble food materials, organic wastes, and hormones regulation of the pH of tissues protection of the body against invading microbes regulation of body temperature in warm – blooded animals TYPES OF CIRCULATION Open-type well-developed blood vessels passing from the heart to the tissues where it opens into spaces called lacunae from these spaces blood returns to the heart through body spaces called hemocoel comes in direct contact with the tissue cells Closed-typed blood is confined inside tubes or blood vessels blood passes from the heart to the tissue and back through these vessels Divisions of closed-typed circulatory system 1. blood vascular system – includes the blood, heart, and blood vessels 2. lymphatic system – includes the lymph or tissue fluid, and lymph vessels 67 THE BLOOD a specialized connective tissue the main transporting medium of the body 8% of total body weight (4 to 6 liters in average adult) considered to be the “essence of life” Composition of Blood Plasma fluid portion of the blood 55% of total blood volume 90 – 92% water, 7-8% plasma proteins, and 1-2% salts and other components average pH of 7.4 Formed elements include the cells (erythrocytes and leukocytes) and cell fragments (thrombocytes) 45% of total blood volume 95% RBC; 5 % WBC and platelets Erythrocytes red blood corpuscles (RBC) small, biconcave disks with polysaccharides on the outer membrane almost the entire interior is packed with hemoglobin 68 about 4-6 million cells per mm3, and each one of these cells contains about 200 million hemoglobin molecules hemoglobin contains 4 globin protein chains each associated with heme, an iron containing group, iron combines loosely with oxygen, and this way oxygen is carried in the blood responsible in the transport of oxygen to body tissues in mammals, short life (less than 4 months), due to lack of nucleus manufactured in the red bone marrow of the skull, the ribs, the vertebrae, and the ends of long bones destroyed in the liver and the spleen when RBC are destroyed, hemoglobin is released, the iron is covered and is returned to the red bone marrow, and the heme portions undergo chemical degradation and are excreted by the liver as bile pigments Leukocytes white blood cells (WBC) less than 1% of the cells in human blood about 5,000 – 9,000 cells/mm3 larger than RBC, with nucleus, no hemoglobin, essentially colorless not confined to the bloodstream, migrate out into the interstitial fluid 69 play important function in the immune system Types of leukocyte 1. granulocytes 2. agranulocytes Types of Granulocytes as to Staining Properties 1. neutrophils 2. eosinophils 3. basophils Types of Agranulocytes as to Function 1. monocytes 2. lymphocytes Thrombocytes called as platelets in humans from fragmentation of megakaryocytes, large cells in the bone marrow; no nucleus involved in blood clotting or coagulation ABO BLOOD CLASSIFICATION the most common blood grouping is the ABO classification based on the types of protein present in the blood cells (antigen A and antigen B) and in the plasma (anti-a and anti-b) 70 agglutination (clumping of blood cells) will form when antigen A combines with anti-a or antigen b combines with anti-b each blood types contains the following: Blood type Type A Type B Type AB Type O Antigen Antigen A Antigen B Antigen A and B no antigen Antibody anti – B Anti – A no antibodies anti – A & anti - B Blood transfusion relationships blood type A can donate to A and AB and can receive from A and O blood type B can donate to B and AB and can receive from B and O blood type AB can donate to AB and can receive from A, B, AB, and O and receive from O, thus called universal donor THE HEART the main pumping organ of the body highly muscular organ located in the mid-ventral region of the thoracic cavity enclosed by a tough connective tissue, the pericardium 71 Chambers of the Heart 1. Atria or Auricles – have thin walls, received blood from the veins and pump it into the ventricle 2. Ventricles – with much thicker walls, pump the blood out of the heart to all parts of the body Types of Heart as to Numbers of Chambers 1. two-chambered heart – found in fishes and it has one auricle and one ventricle 2. three-chambered heart – found in amphibians and reptiles, it has two auricles and one ventricle. It exhibits double but incomplete circulation but there is slight mixing of venous and arterial blood in the ventricle 3. four-chambered heart – found in birds and mammals, it has two auricles and two ventricles, exhibits double and complete circulation, no mixing of venous and arterial blood in the ventricle The Human Heart cone-shaped muscular organ about the size of a fist located between the lungs, tilted, the apex is directed to the left internally, the left and right side is separated by a septum 72 atria and ventricles are separated by atrioventricular valves, tricuspid valve on the right and bicuspid valve on the left between ventricle and its vessels, regulated by a semilunar valve, pulmonary and aortic semilunar valves The Heartbeat about 70 times/minute, each heartbeat lasts about 0.85 sec cardiac cycle includes systole (contraction of heart muscle) and diastole (relaxation of heart muscle) contraction is intrinsic (outside nervous stimulation) due to nodal tissue SA (sinoatrial) node in the upper dorsal wall of right atrium, initiates atrial contraction, also called as pacemaker AV node (atrioventricular) node in the base of the right atrium, initiates ventricle contraction expels 60 ml of blood per beat THE BLOOD VESSELS Types of Blood Vessels as to Direction of Blood Flow Arteries carry oxygenated blood away from the heart, except pulmonary arteries, which carry 73 deoxygenated blood away from the heart going to the lungs; branched into arterioles connecting small arteries to capillaries Capillaries connect arterioles and venules; about 0.5 to 1 mm long; could be found in the metabolic organs Veins carry deoxygenated blood towards the heart, except pulmonary veins, which carry oxygenated blood towards the heart; branched into venules, connecting small veins to capillaries Layers of the Blood Vessels (except capillaries and venules) 1. tunica intima (inner layer) includes endothelium 2. tunica media (middle layer) includes elastic and smooth muscle tissue 3. tunica adventitia or tunica externa (outer layer) 74 CIRCULATION PATTERNS Pulmonary circulation blood flow through the system of blood vessels that carry blood from the right ventricle of the heart to the lungs and from the lung and back to the left atrium Systemic Circulation blood flow through the system of blood vessel that carry blood from the left ventricle of the heart to the tissues of the body and back from the body to the right atrium PATHWAY OF BLOOD (BLOOD CYCLE) body tissues ( capillaries ) – for collection of CO2 and wastes venules and veins superior and inferior vena cava right atrium of the heart tricuspid valve right ventricle pulmonary semilunar valve pulmonary aeteries lungs (alveoli/capillaries) – for gas exchange pulmonary veins left atrium of the heart bicuspid valve 75 left ventricle aortic semilunar valve dorsal aorta arteries and arterioles body tissues (capillaries) – for distribution of O2 and nutrients COMMON BLOOD-RELATED DISORDERS Hypertension or High Blood Pressure Thrombosis Leukemia Arteriosclerosis Hemophilia 76 RESPIRATORY SYSTEM FUNCTIONS exchange of gases oxidation of food molecule in order to produce energy in the form of ATP TYPES OF RESPIRATION Direct Respiration exchange of gases between the cells of an organism and the environment essential gases are oxygen and carbon dioxide Indirect Respiration exchange of gases through specialized organs and involves two phases, external (between blood and environment) and internal (between blood and body cells) RESPIRATORY ORGANS Direct Surfaces (skin and pharyngeal regions) – some amphibians and fishes like mudhopper and eels use their skin, salamanders use their pharyngeal regions Gills – most aquatic animals use external or internal gill filaments Lungs – terrestrial animals Characteristics of a Good Respiratory Organ 77 have a large surface area, to accommodate greater amount of gases be thin, for it will take gases the shortest time possible to pass through it be moist, for the gases will be dissolved be permeable so that gases dissolved in water can pass through it be accessible to the source of oxygen and be elastic, to accommodate more air PARTS OF RESPIRATORY TRACT nostrils or external nares – outer opening for entrance of air nasal chamber of cavity – lined with mucus-secreting and ciliated epithelium internal nares – posterior opening connected to the pharynx pharynx – or throat, common passageway of air from the nasal cavity and food from the oral cavity glottis – opening of the cartilaginous larynx, covered by a flap of tissue, the epiglottis, to prevent food from entering the glottis when swallowing larynx – or voice box containing the vocal chords trachea – or windpipe made up of rings of cricoid cartilages bronchi (bronchus) – leading to the lungs 78 bronchioles – smaller branches of each bronchus (secondary and tertiary bronchi) within the lungs alveoli (alveolus) – or air sacs, thin and moist, site of gas exchange between the alveoli and adjacent blood capillaries; in man, there are about 300 million alveoli with a total surface area of about 70 square meter (half an area of a tennis court) LUNGS composed of elastic tissue and some muscles in human, covered by visceral pleura, a thin layer of smooth epithelium located at the pleural cavity lined with parietal pleura diaphragm, a dome-shaped muscular partition from the floor of the chest cavity separates the pleural cavities from the abdominal cavity right lung is divided into three lobes, the left into two Pulmonary Volume tidal volume – volume of air inspired or expired during quiet breathing, about 500 ml (tidal air; 350 ml reach the alveoli and 150 ml left in the respiratory passages) inspiratory reserve volume – amount of air that can be inspired forcefully after inspiration of the normal tidal volume, about 3000 ml (complimental air) 79 expiratory reserve volume – amount of air that can be expired forcefully after expiration of normal tidal volume, about 1100 ml (supplemental air) residual volume – volume of air still remaining in the respiratory passages and lungs after maximum expiration, about 1200 ml (residual air) Pulmonary Capacities vital capacity – sum of tidal air, complimental air, and supplemental air, the maximum volume of air that a person can expel from his respiratory tract after a maximum inspiration, about 4600 ml inspiratory capacity – sum of tidal air and complimental air, amount of air that a person can inspire maximally after normal expiration, about 3500 ml functional residual capacity – sum of supplemental air and residual air, amount of air remaining in the lungs at the end of normal expiration, about 2300 ml total lung capacity – sum of tidal air, complimental air, supplemental air, and residual air, about 5800 ml; equal to the vital capacity plus the residual air MECHANICS OF BREATHING During Inspiration diaphragm and other chest muscles contract 80 ribs also expand volume of thoracic cavity increases the pressure in the lungs fall below atmospheric pressure air rushes in to equalize the pressure through the nostrils going to the alveoli During Expiration diaphragm and other chest muscles return to normal, relax position ribs also return to normal position size of thoracic cavity reduced lungs contract forcing the air out due to increase in pressure COMMON DISEASES ASSOCIATED WITH RESPIRATORY SYSTEM common colds asthma bronchitis pneumonia tuberculosis (TB) 81 EXCRETORY SYSTEM FUNCTIONS collection and elimination of metabolic waste products maintains homeostatis METABOLIC WASTES heat carbon dioxide from respiration water derived from the oxidation of carbohydrates and fats bile salts and pigments from the destruction of RBC mineral salts from the breakdown of other worn-out tissues and from excess dietary intake urea from protein metabolism HUMAN EXCRETORY SYSTEM located in the lower abdomen excretory structures include the kidneys, urinary bladder, ureters, and urethra the main wastes collected is called urine the other organs for excretion include the liver, lungs and skin 82 Kidneys paired, bean shaped organs located on both sides of the spinal column around 5 in long 3 in wide and 1 in thick composed of over one million nephrons organs for homeostatis for they regulate the composition of the blood Blood Supply of the Kidney renal artery – carry blood with dissolved cellular wastes into the kidney renal vein – carry filtered blood out of the kidney Internal parts of the kidney cortex – outer granulated layer medulla – radially striated or lined layer renal pelvis – inner space or cavity continuous with the ureter Structure of the Nephron Renal corpuscle or corpuscles of Malphigii glomerulus – composed of several looped capillary vessels which connect afferent arteriole (entry of blood) with the efferent arteriole(exit of blood) Bowman’s capsule – encloses the glomerulus 83 Renal tubules capsule – expanded as the Bowman’s capsule enclosing the glomerulus proximal convoluted portion – connected to the capsule, about 14mm in length and 60µm in diameter loop of Henle – consisting of two straight (ascending and descending) limbs running parallel to each other distal convoluted portion – short and much convoluted leading to a short, arched connecting potion, which empties into a straight collecting duct leading to the renal pelvis Steps of Urine Formation Pressure filtration -small molecules (water, glucose, amino acids, salts, urea, uric acids) from the glomerulus were forced by the blood into the Bowman’s capsule Selective Reabsorption - molecules (water, glucose, amino acids, salts) return to the blood at the proximal convoluted tubule through diffusion and active transport 84 Tubular secretion -molecules (uric acid, creatinine, ammonia) from the blood moved into the distal convoluted tubule through active transport Reabsorption of water -water returns by osmosis following active reabsorption of salts along the length of the nephron and notably at the loop of Henle and collecting duct Excretion -urine is formed and goes out of the kidney through the pelvis and ureter going into the urinary bladder for temporary storage COMMON KIDNEY DISORDERS Acute renal failure Chronic renal failure Urinary calculi 85 NERVOUS SYSTEM FUNCTIONS coordination and integration of many activities of the body through the conduction of impulses from the receptors to the effectors ORGANIZATION OF THE NERVOUS SYSTEM Origin develops from an embryonic dorsal hollow nerve cord Composition brain, spinal cord, nerve cells, neuroglial cells consist of vast increase in the number of neurons compared to invertebrates consists of several types of paired sensory receptors due to cephalization and bilateral symmetry Divisions Central Nervous System (CNS) – includes the brain and the spinal chord Peripheral Nervous System (PNS) – includes all the nerve cells outside the CNS, both the cranial nerves and the spinal nerves 86 NEURONS nerve cells for reception of stimuli and transmission of reactions responsible for the integration of impulses composition of the brain Parts of a Neuron Cell body -part of a neuron where nucleus and other organelles are located Protoplasmic processes axon – a long cylinder that conducts nerve impulses away from the cell body; covered by tightly packed spiral of Schwann cells containing myelin serve as insulator and considered as glial cells (with supportive and nutritive functions) dendrite – short, highly branched extensions that conduct nerve impulses toward the cell body Types as to Number of Protoplasmic Process unipolar neuron – with only one protoplasmic process; found in dorsal root ganglion of the spinal chord bipolar neuron – with two protoplasmic processes (axon and dendrites); found in the retina of the eye 87 multipolar neuron – with several dendrites and one axon; found in ventral horns of the grat matter of the spinal cord Types as to Functions sensory neurons – transmit impulses from sensory receptors of the sense organ to nerve center (CNS) motor neuron – transmit impulses from the nerve center to the effectors (muscles or glands) adjustor or associative neuron – connects sensory and motor neuron; located in the nerve center, also called interneuron NEUROGLIAL CELLS supporting cells of the nervous tissue composed of actively dividing cells can cause brain tumor Types as to Structure and Function astrocytes – star-shaped neuroglial cells, connect neurons and capillaries microglia – phagocytes, dispose dead cells, bacteria, etc. ependymal – line the fluid-filled cavities of the CNS for protection oligodendrocytes – form the myelin sheath around the fibers Schwann cells and satellite cells 88 CENTRAL NERVOUS SYSTEM lies in the midline of the body most of the cells are neuroglial cells consists of the spinal cord and the brain where nerve impulses are coordinated and interpreted Spinal cord continuation of the base of the brain surrounded by vertebrae; covered by three protective membranes (meninges); the spaces between the meninges are filled with cerebrospinal fluid (CSF), which cushion and protect the CNS; CSF is also contained in the central canal of the cord; Two main functions of the spinal cord center for many reflex actions; provides means of communication between the brain and the spinal nerves Gray Matter consist of cell bodies and short unmyelinated fibers; H-shaped in a cross section; includes interneurons and portions of sensory neurons and motor neurons 89 White Matter consist of bundles of myelinated long fibers of interneurons (tracts) connects the spinal cord to the brain dorsally, contains ascending tracts taking information to the brain ventrally, contains descending tracts carrying information from the brain Brain most specialized organ of the body located in the cranial cavity of the skull made up of soft nervous tissue covered by three membranes or meninges Meninges of the Brain pia mater – innermost membrane; closely adhering to the surface of the brain and dipping down into its many folds; well supplied with blood vessels that carry food and oxygen to the brain arachnoid mater – middle membrane; made up of fibrous and elastic connective tissues; separated to the pia mater by the cerebrospinal fluid dura mater – outermost membrane; thick and tough linings of the cranium 90 Hemispheres of the Brain left hemisphere – controls the right side of the body right hemisphere – controls the left side of the body Divisions of the Brain cerebrum cerebellum diencephalons (hypothalamus and thalamus) the brain stem (medulla oblongata, pons and midbrain) Cerebrum foremost part and largest part (in humans) of the brain the seat of consciousness, intelligence, sensory perception of sight, olfactory, and auditory senses, and coordination of body movement controls the activities of the lower parts of the brain can override the functioning of the brain stem and diencephalons can initiate voluntary motor activities and controls the actions of the cerebellum consists of two large masses called cerebral hemispheres, connected by corpus callosum Lobes of Cerebrum frontal lobe – responsible for the elaboration of conscious thought and control the movement of skeletal muscles; includes the motor elaboration, 91 articulation, mastication, deglutition, and movement of tongue, lips, hands, arms and legs parietal lobe – responsible for the sensations of temperature, touch, pressure, and pain from the skin; includes salivation and sensory elaboration of the mouth, lips, tongue, hands, arms, and legs temporal lobe – responsible for hearing and smelling, visual and auditory recollection, and perceptual judgment occipital lobe – responsible for vision Cerebellum lies below the posterior portion of the cerebrum separated from the brain stem by the fourth ventricle functions in muscle coordination, posture and balance Diencephalon Hypothalamus forms the floor of the third ventricle maintains homeostasis of the internal environment contains center for regulating hunger, sleep, thirst, body temperature, water balance, and blood pressure controls the pituitary gland, serves as a link between the nervous and endocrine systems 92 Thalamus forms the sides and roof of the third ventricle the last portion of the brain for sensory input before the cerebrum serves as a central relay station for sensory impulses and channels them to appropriate regions of the cerebrum for interpretation The Brain Stem Medulla oblongata lies between the spinal cord and the pons, anterior to the cerebellum contains a number of vital centers for regulating heartbeat, breathing, and blood pressure also contains reflex centers for vomiting, coughing, sneezing, hiccupping, and swallowing contains tracts that ascend or descend between the spinal cord and the brain Pons contains bundles of axons traveling between the cerebellum and the rest of the CNS helps in regulating breathing rate contains reflex centers concerned with head movements in response to visual and auditory stimuli 93 Midbrain act as a relay station for tracts passing between the cerebrum and the spinal cord or cerebellum contains reflex centers for visual, auditory, and tactile responses PERIPHERAL NERVOUS SYSTEM lies outside the CNS contains both cranial and spinal nerves Nerves bundles of long neuron fibers held together by connective tissue sensory nerves contain sensory fibers, motor nerve contain motor fibers, and mixed nerves contain both types of fibers Cranial nerves in humans, there are 12 pairs of cranial nerves attached to the brain some of these are sensory nerves and others are mixed nerves mainly concerned with the head, neck, and facial regions of the body include the vagus nerve which has branches to the pharynx and larynx and most of the internal organs 94 Spinal nerves in humans, there are 31 pairs of spinal nerves emerged from the spinal cord emerge from the spinal cord by two short roots – dorsal root and ventral root dorsal root contain the axons of sensory neurons which conduct impulses to the cord ventral root contain the axons of motor neurons which conduct impulses away from the cord all spinal nerves are mixed nerves conducting impulses to and from the spinal cord Somatic System includes all nerves that serve the skeletal muscles (effectors) and exterior sense organs including those in the skin (receptors) initiate reflex action Automatic System includes all nerves that serve the internal organs automatically and usually without need for conscious intervention function automatically and subconsciously; innervate internal organs utilize 2 motor neurons (the first has a cell body within the CNS and a preganglionic fiber, the second 95 has a cell body within the ganglion and a postganglionic fiber) and 1 ganglion for each impulse divided into sympathetic and parasympathetic systems Sympathetic System fight or flight norepinephrine (NE) is neurotransmitter postganglionic fiber is longer than preganglionic fiber preganglionic fiber arises from the middle portion of the cord important during emergency situations accelerates heartbeat, dilates the bronchi, increases the breathing rate inhibits digestive tract Parasympathetic System “housekeeper” of the nervous system acetylcholine (Ach) is neurotransmitter preganglionic fiber is longer than postganglionic fiber preganglionic fiber arises from the brain and lower portion of the cord promotes all the internal responses with a relaxed state; retards heartbeat, promotes digestion 96 Reflexes automatic, involuntary responses to changes occurring inside or outside the body some reflexes involve the brain others involve only the spinal cord and a spinal nerve (reflex arc or spinal reflex) Reflex Arc major functional unit of the nervous system allows us to react rapidly to internal and external stimuli Steps of reflex arc nerve impulses move along the axon of a sensory neuron toward the cell body located outside the cord from the cell body of the sensory neuron, the impulses are picked up by an interneuron lies within the cord then pass to the dendrites and the cell body of a motor neuron that lies ventrally within the cord the impulses will leave the cord by way of the ventral root traveling along the axon of the motor neuron going to the muscle fibers, which contracts TYPES OF RECEPTORS Chemoreceptors stimulated by changes in the chemical concentration of substances 97 located in the nasal cavity and the tongue as olfactory receptors Thermoreceptors stimulated by changes in temperature located in the skin as free nerve endings Mechanoreceptors stimulated by changes in pressure and movement located in the inner ear, skin, and muscles and tendons as hair cell, specialized nerve endings and as free nerve endings respectively Photoreceptors stimulated by light energy located in the retina of the eyes as rods and cones Pain receptors stimulated by tissue damage located widespread in the body as free nerve endings COMMON DISEASES ASSOCIATED WITH NERVOUS SYSTEM Epilepsy Multiple Sclerosis (MS) Meningitis Mental illness Stroke 98 ENDOCRINE SYSTEM FUNCTIONS Coordinates, together with the nervous system, the activities of the body Involved in the synthesis and secretion of hormones Hormonal functions include: control of energy production and utilization control of the composition of extracellular water and electrolytes maintains normal growth and development ENDOCRINE GLANDS ductless glands that synthesize and secrete hormones a hormone is an organic substance needed by the body in minute quantities to elicit a specific physiological response hormones are produced by one part of the body that have an effect on specific target cells located in different parts of the body Hypothalamus a small gland about 1.0 cm in diameter located at the base of the brain intimately associated with the pituitary gland secretes releasing hormones that travel via a portal system and stimulate the anterior pituitary 99 Pituitary Gland a small gland located at the base of the brain in the depression of the skull connected to the brain through a short stalk called infundibulum Divisions of the pituitary gland anterior lobe or adenohypophysis secretes 6 hormones FSH, follicle-stimulating hormone LH, luteinizing hormone (in female) or ICSH, interstitial cell-stimulating hormone (in male) luteotrophic hormone or prolactin ACTH, adrenocorticotrophic hormone TSH, thyroid-stimulating hormone STH, somatotrophic hormone or GH, growth hormone posterior lobe or neurohypophysis secretes 3 hormones: vasopressin, for constriction of the vessels ADH, antidiuretic hormone oxytoxin, controls smooth muscles Thyroid Gland composed of two lobes, on each side of the trachea connected by an isthmus 100 secrete thyroxin that regulate growth and development enlargement of this gland results in a condition known as goiter Parathyroid Gland small glandular bodies located on the dorsal surface of the thyroids secrete parathormones (PTH) that maintains the ration of calcium and phosphorus in the body Thymus Gland located between the upper part of the sternum and the pericardium a temporary organ which reaches greatest development at age 14 to 16 secretes thymosin that controls metabolic rate and involved in the formation of WBC Adrenal Cortex secretes cortisol and aldosterone that causes gluconeogenesis and sodium retention and potassium excretion in the kidneys respectively Adrenal Medulla two small masses located above the kidneys secrete epinephrine and norepinephrine promotes “fight or floght” reactions during emergency 101 Pancreas both an exocrine and endocrine gland the endocrine part consists of the islets of Langerhans that secrete the hormones insulin insulin lowers the blood sugar, little secretion resulted into diabetes mellitus Gonads the interstitial cells (Leydig cells) of the testes secrete testosterone the follicles of the ovary secretes estrogen, the corpus luteum secretes progesterone 102 REPRODUCTIVE SYSTEM Function: ASEXUAL REPRODUCTION only one parent is involved no special reproductive organs or cells are required ensures rapid increase in number exhibited only among lower forms of life such as bacteria, fungi and lower forms of invertebrates Methods of Asexual Reproduction Fission – the body of the parent is divided into two approximately equal parts, transverse or longitudinal, each of which develops into a new individual similar to the parents; common among protozoan Budding – the organism is unequally divided and the new individual evolves as an outgrown (bud) from the parent; common in hydra and freshwater sponges Fragmentation – the individual breaks or splits into two or more parts, each part capable of becoming a complete individual; common among flatworms and echinoderms Sporulation – the numerous cells produced are enclosed in a cyst-like structure so that a part of it surrounds each of the several daughter nuclei after repeated divisions; common among sporozoans; also called multiple fission Regeneration – the capacity to replace or regenerate parts lost by injury; common among echinoderms and planaria 103 SEXUAL REPRODUCTION involves two parents, male and female each parent is provided with a reproductive organ (gonad) for the production of reproductive cells (gametes) for the male, gonads are paired testes that produce the sperm cells for the female, gonads are paired ovaries that produce the egg cells Methods of Sexual Reproduction Conjugation – two individuals fuse together and exchange micronuclei and then separate to continue binary fission; common among protozoan and ciliates Parthenogenesis – a modified form of sexual reproduction wherein an unfertilized egg develops into a complete individual; common among rotifers, ants, bees, and crustaceans Hermaphroditism – both male and female sex organs are present in the same individual (hermaphrodite or monoecious) but does not reproduce by selffertilization; two individuals exchange germ cells with each other in cross-fertilization; common among lower forms of animals, such as flatworms and earthworms; some do reproduce by self-fertilization such as tapeworms and snails; protoandry, if the 104 sperm cells are formed first; protogyny, if the egg cells are formed first Biparental reproduction – exhibited by dioecious animals; it involves separate and distinct male and female individuals, each of which has its own reproductive system; fertilization may take place externally or internally HUMAN MALE REPRODUCTIVE SYSTEM Sex organs (gonad) – testes Sex cells (gametes) – sperm cells Sex hormones – testosterone External structure Penis the copulatory organ, responsible for the transfer of sperm cells into the female reproductive tract cylindrical organ that usually hangs (flaccid) in front of the scrotum composed of the shaft, glans penis and a foreskin (prepuce) covering the glans penis composed of 3 cylindrical columns of spongy, erectile tissue containing blood spaces during sexual arousal, arterial blood flow fills the blood spaces in the erectile tissue that causes erection the release of semen is called ejaculation 105 Scrotum pouch containing the testes that hangs down as an appendage of the body also serves as a thermoregulator to protect the sperm cell against changes in body temperature (1.0 to 1.5oC cooler than the body temperature) Internal Structure Testes the male sex organ suspended within the scrotal sac of the scrotum composed internally of numerous seminiferous tubules embedded within the interstitial cells seminiferous tubules are responsible for the formation of the male gametes, sperm cells; immature sperm cells move from the seminiferous tubules to the epididymis to mature, about 20 days interstitial cells are responsible for the production and secretion of the male sex hormones, testosterone Ducts tubes that conduct the sperm cell/semen vas eferens (vasa eferentia) – tiny tubes connecting the seminiferous tubules of the testis to the coiled epididymis; 106 epididymis (epididymides) – the coiled part of the sperm duct that lies near the testis for temporary storage of matured sperm; vas deferens (vasa deferentia) – coiled tube carrying sperm from the epididymis to the urethra during ejaculation; ejaculatory duct – a part of the sperm duct connecting the vas deferens to the urethra where fluid secreted by the sex glands are mixed with the sperm urethra – the tube that conducts both the urine from the urinary bladder and the semen from the testes during ejaculation Glands organs that produces seminal fluid seminal vesicle (vesicular gland) – lie at the base of the bladder, joining the vas deferens to form the ejaculatory duct, secrete thick, viscous fluid containing fructose and alkaline substance for the survival of the sperm prostate gland – a mass of glandular tissue at the base of the urethra that secretes an alkaline fluid that has a stimulating effect on the sperm as they are released Cowper’s gland (bulbo-urethral gland) – located slightly below the prostate gland secreting mucous fluid for lubrication 107 HUMAN FEMALE REPRODUCTIVE ORGAN Sex organs (gonads) – ovaries Sex cells (gametes) – egg cells Sex hormones – estrogen and progesterone External Structure (collectively called as vulva, the external female genitali) Mons pubis (mons veneris) a pad of a fatty flesh located above and in front of the labia, normally covered with pubic hair after puberty Labia two sets of lips that protect the entrance to the vagina; made up of outer and larger folds of skin covered with pubic hair called labia majora and inner labia minora located beneath the labia majora Clitoris A bud or projection of sensitive erectile organ located at the anterior part of the labia at the juncture of the labia minora, often hidden beneath a hood of flesh called the prepuce Vestibule the opening into the vagina, normally guarded by a thin membrane called hymen in the virgin state 108 Urethral opening opening of the urethra for the excretion of urine Internal Structure Ovary the female sex organ lodged within the peritoneal cavity where they are held in position by mesenteries or ligaments composed internally of numerous follicle each containing an egg cell follicles contain the female gamete, egg cell, that will undergo maturation for a cycle of 28 days also responsible for the production and secretion of the female sex hormones, estrogen before ovulation and progesterone after ovulation ovulation is the release of egg cell (secondary oocyte) from the follicle of the ovary Fimbriae fingerlike projections at the end of each oviduct that capture or sweep the egg cell during ovulation Fallopian tube (oviduct) the egg carrying tubes extending from the ovaries to the uterus where fertilization takes place 109 the inner wall is lined with cilia for the propulsion of the egg during its course down to the uterus for about 12 to 24 hours Uterus (womb) special hollow organ where the embryo develops for 9 months during pregnancy; provided with thick muscular wall, numerous blood vessels and specialized lining called endometrium implantation of the fertilized egg cell takes place a week after fertilization varies with different mammals, simplex in man, duplex in rodents, bicornuate in horses and bipartite in cats Cervix a muscular ring of tissue at the mouth of the uterus protruding into the vagina Vagina hollow muscular tube leading to the outside, with elastic wall not only for the reception of the male penis during copulation but also for the passage of infant during childbirth 110 SEX HORMONES hypothalamus controls the sexual functions of the gonads, it secretes gonadotropin-releasing hormone (GnRH) that stimulates the anterior pituitary gland to produce follicle stimulating hormone (FSH) and luteinizing hormone (LH), LH is called interstitial cell-stimulating hormone (ICSH) in males FSH promotes formation and maturation of sperm cell (spermatogenesis) in the seminiferous tubules of the testes and the development of an egg cell (oogenesis) in the follicle of the ovary LH promotes the development of the corpus luteum which secretes progesterone ICSH controls the production of testosterone by the interstitial cells Testosterone the main sex hormone in males produced by the interstitial cells of the testes essential for the normal development and functioning of the reproductive organs necessary for the maturation of sperm cells brings about and maintains the secondary sexual characteristics that develop during puberty stage: taller heights broader shoulders deeper voice 111 greater muscular development hair on face, chest arms, legs and other parts of the body causes receding hairline and baldness Estrogen and progesterone main sex hormones in females estrogen is produced by the developing follicle of the ovary and progesterone by the corpus luteum after ovulation estrogen is essential for the normal development and functioning of the reproductive organs mainly estrogen brings about and maintains the secondary sexual characteristics that develop during puberty stage soft and rounded body appearance due to greater accumulation of fats beneath the skin softening of the skin wider hips due to the enlargement of the pelvic girdle both estrogen and progesterone are responsible for the development of the breast MENSTRUAL CYCLE Ovarian Cycle primary follicles containing primary oocytes begin producing estrogen 112 secondary follicles containing secondary oocytes continue producing estrogen graafian follicle develops secondary oocytes surrounded by follicle cells is released (ovulation) corpus luteum produces progesterone corpus luteum degenerates Uterine Cycle Menstrual Period (from day 1 to 5) low level of female sex hormones in the body causing the uterine lining to disintegrate and its blood vessels rupture a flow of blood (menses) passes out of the vagina (menstruation) Proliferative phase (day 6 to 13) increased production of estrogen by an ovarian follicle causes endometrium to thicken and to become vascular and glandular Ovulation (day 14) graafian follicle burst and the secondary oocyte is released from the ovary 113 Secretory phase (day 15 to 28) increased production of progesterone by the corpus luteum causes the endometrium to double the thickness and the uterine glands to mature producing a thick mucoid secretion ready to receive the developing embryo EMBRYOLOGY concerned with the origin of the body structures of an individual and its developmental processes the study of the development of an egg from the time of its maturation until the organism is completely formed embryo refers to the offspring in the uterus from weeks 2 through 8 of development EMBRYONIC MEMBRANES 1. Amnion – a thin membrane derived from the embryonic cell layers that forms a fluid – filled pouch, which loosely envelops the embryo and fetus until birth 2. Chorion – a membrane derived from embryonic cell layers that surrounds and protects the embryo and fetus, part of the chorion joins with the uterine lining and develops into the placenta 114 3. Allantois – a membrane derived from the embryonic tissue that contains blood vessels which develops into the blood vessels of the umbilical cord 4. Yolk sac – a balloon – like membrane surrounding a cavity containing nutrients and blood cells for the embryo from week 2 after fertilization until the placenta has fully developed COMMON SEXUAL DISEASES AND DYSFUNCTION Erectile dysfunction Female orgasmic dysfunction Vaginismus Breast Cancer Sterility Infertility Gonorrhea Syphilis Genital herpes AIDS Trichomoniasis 115 BASIC GENETICS: DEFINITION OF TERMS Genetics – the study of heredity and variation Heredity – the transmission of traits from one generation to another, from parents to offspring; the protoplasmic continuity between parents and offspring Variation – any difference existing between individuals of the same species Chromosome – rod-shaped in the nucleus of eukaryotes and prokaryotes that contains the hereditary units or genes; seen particularly during cell division Gene – the unit of heredity occupying a particular location on the chromosome and passed on to offspring Locus – the location of a gene on a chromosome Diploid – the 2N number of chromosomes; twice the number of chromosomes found in gametes Haploid – the N number of chromosomes; half the diploid number; the number characteristic of gametes that contain only one set of chromosomes F1 generation – first filial generation; the firstgeneration offspring of a genetic cross that has at least two generations F2 generation – second filial generation; the second generation offspring of a genetic cross 116 Homozygous – a pair of similar or like genes for any one character Heterozygous – a pair of contrasting traits of two kinds of genes Genotype – the particular genes of an individual that determine a specific trait Phenotype – the outward appearance of an organism, caused by genetic and environmental influences Allele – a pair of similar or contrasting characters; one of two or more alternative states of a gene Dominant allele – hereditary factor that expresses itself when the genotype is heterozygous Recessive allele – hereditary factor that expresses itself only when the genotype is homozygous Hybrid – the offspring of two parents that differ in one or more heritable characters Monohybrid cross – cross in which the parents differ in one pair of alternative characters Dihybrid cross – cross in which the parents differ in two pairs of alternative characters Homologous chromosomes – a pair of chromosomes that have the same shape and contain genes for the same traits Mutation – a sudden change in the genetic make-up; an abrupt and heritable modification of a character 117 TESTCROSS used to determine if an individual expressing dominant trait is homozygous or heterozygous the results indicate whether an individual who has phenotype is heterozygous or homozygous if any of the offspring of a testcross have phenotype determined by the recessive allele, parent with the dominant phenotype must heterozygous the the the the be MONOHYBRID CROSS one-trait testcross if the parent expressing the dominant trait is homozygous, none of the offspring will show the recessive characteristics but if the parent expressing the dominant trait is heterozygous, there is a 50% chance that any offspring will show the recessive characteristics DIHYBRID CROSS two-trait testcross if the parent expressing the dominant trait is homozygous, one of the offspring will show the recessive characteristics but if the parent expressing the dominant trait is heterozygous, there is a 75% chance that an offspring will show at least one of the recessive characteristics 118 PUNNETT SQUARE a “checkboard” grid designed to determine all possible genotypes produced by a given cross introduced by poultry geneticist, R. Punnett in early 1900’s GREGOR JOHANN MENDEL an Austrian Augustinian monk; born in 1822 to peasant parents; studied science and mathematics at the University of Vienna where he failed an exam for a teaching certificate; taught natural science at a local technical school; formulate center laws of heredity in early 1860’s; Before Mendel the belief was Blending Theory of Inheritance; both sexes contribute equally to a new individual; a cross between plants with red flowers and plants with white flowers would yield only plants with pink flowers; The Work of Mendel Mendel’s Experiments he chose to work with the garden pea, Pisum sativum; this plant was easy to cultivate and had a short generation time; he choose 22 varieties of peas; when these varieties self-pollinated, the offspring were like the parent plants and like each other; 119 he cross-pollinated the varieties for his experiment; studied the inheritance of relatively distinguishable traits seed shape, seed color, and flower color; he followed the inheritance of individual traits, he gathered statistical data and used his understanding of mathematical laws of probability to interpret the results. Mendel’s Conclusion Mendel’s First Law: LAW OF SEGREGATION “Each organism contains two factors for each traits, and the factors segregate (separate) during the formation of gametes so that each gamete contains only one factor for each trait. When fertilization occurs, the new organism has two factors for each trait, one from each parent.” Mendel’s Second Law: LAW OF INDEPENDENT ASSORTMENT “Members of one pair of factors segregate (assort) independently of members of another pair of factors. Therefore, all possible combinations of factors can occur in the gametes.” SOLVING GENETIC PROBLEMS Know which characteristic is dominant. 120 Decide on the appropriate key. Recommended use is the first letter of the recessive trait. Determine the genotype of the parents. Determine all possible types of gametes for both parents. Choose what method will be used, Punnett square or forked-line method. Some common human traits Human traits Dominant Skin Freckles Pigmentation Hairline Widow’s peak Unattached Earlobes (Free lobes) Red-green Color vision vision Hair on back of Present hand Left thumb over Interlace fingers right Bent towards Bent little finger ring finger Hair form Curly hair Eye lashes Long eyelashes Ability to curl Tongue tongue 121 Recessive No freckles Continuous Attached Red-green blindness Absent Right thumb over left Straight Straight hair Short eyelashes Inability to curl the tongue SEX-LINKED TRAITS (HUMAN) Genes which are carried on the sex chromosomes, mostly on the X chromosomes only and not on the Y There are now more than 120 known sex linked traits in humans. FEW EXAMPLES OF SEX-LINKED TRAITS: TRAITS DESCRIPTIONS 1. HEMOPHILIA a condition where the blood lacks agents necessary to cause clotting of blood following an injury a heredity disorder common among the royal families 2.COLOUR the inability of an BLINDNESS individual to distinguish between the colours red and green 3. OPTIC TROPHY a deterioration of optic nerve 4.JUVENILE GLAUCOMA a condition leading to hardening of the eyeball from increased internal pressure 122 a condition where a person can see objects clearly close up but not a distance premature loss of hair common among males 5.MYOPIA 6. BALDING Each Human cell contains 23 pairs of chromosomes, including the two sex chromosomes (xy) Number of chromosomes in Human – 46 Female eggs 22pairs of somatic chromosomes and X – sex chromosomes 22-X (Homogametic sex) MALE SPERM 22-X 22-Y (HETERO GAMETIC SEX) 123 CHROMOSOMAL BASIS OF SEX DETERMINATION 22 X 22 X Egg sperm [P(x)=1] [P(x)=1/2] 22 X Egg [P(x)=1] 44 XX 22 Y sperm [P(y)=1/2] 44 XY FEMALE ZYGOTE MALE ZYGOTE SIGNIFICANCE OF SEX CHROMOSOMAL ABERRATIONS (ABNORMALITIES) CAUSES: 1. Nature also makes mistakes. Certain mechanisms may fail during meiosis or mitosis, causing failure of the homologous chromosomes to separate during anaphase (non-disjunction) producing certain eggs with two xchromosomes or none (22-xx or 22-o) instead of one (22x) 124 2. ENVIRONMENTAL FACTORS increasing chemical pollution drug abuse viral infections ionizing radiation (gamma, x-ray, beta or alpha particles) radio isotopes in medicine, industry radioactive wastes from nuclear reactors fallouts of nuclear weapon testing THE HUMAN GENETIC DISORDER: CYSTIC FIBROSIS – condition arises from the production of abnormal amounts of mucous secretions by the lungs and the pancreas HUNTINGTON’S DISEASE – a nervous disorder which usually appear between 35 and 45 years of age (mid-life) - symptoms includes loss of memory, severe depression, anger, difficulty in speaking and swallowing PHENYLKETONURIA (PKU) – a disease caused by the inability of the body to produce a specific enzyme required to break down a protein in itself. 125 CHROMOSOMAL DISORDERS: 1. DOWN SYNDROME (MONGOLISM) No. of chromosomes (47) with extra 21 chromosomes CHARACTERISTICS: mental retardation poor muscle development large tongue slanted eyes flat forehead 2. KLINEFELTER’S SYNDROME No. of chromosomes (47) with extra x chromosome (xxy) small testes sterility (devoid of germ cells) tall, slim with developed breast frequent mental retardation 3. TURNER’S SYNDROME No. of chromosomes (45) with the x chromosome only (xo) failure to develop secondary sex characteristics of female short stature webbed neck 126 flat chested sterility in females 4. SUPER MALE/META MALE No. of chromosomes (47) with extra y chromosomes (xyy) neither the super/bionic man nor the usual male sex symbols mental retardation possible cause of violent behavior 5. SUPER FEMALE/METAFEMALE No. of chromosomes (47) with extra x chromosome (xxx) neither the super/bionic woman nor the usual female sex symbols mental retardation short, stocky, flat chested generally sterile TREATING/DETECTING GENETIC DISORDERS OR DISEASES KARYOTYPING – process that can be used to detect a number of chromosomal abnormalities which in turn are indicators of possible future genetic disorders AMNIOCENTESIS – a prenatal diagnostic technique in which amniotic fluid is removed and the cells 127 present used to produce a karyotype of the fetus which can yield vital information in detecting any abnormalities ULTRA SOUND – technique that enables the doctor to locate the exact position of the fetus ona monitor, thus ensuring the fetus is not accidentally injured during amniocentesis POST NATAL DIAGNOSIS – very useful in the detection of genetic disorders of biochemical origin a. SERUM TEST (blood extraction) - can detect cystic fibrosis -immediate medical treatment such as antibiotics and pulmonary therapy can extend the life expectancy b. PKU SCREENING- done on all new borns within the first two weeks of birth - has lead to a decrease in the number of fatalities caused by PKU (phenylketonuria) GENE TECHNOLOGY (The Artificial Intervention in Genetics) BIOTECHNOLOGY – the use of scientific and engineering principles to manipulate organisms. GENETIC ENGINEERING – the science applied to the manipulation of genes to improve the characteristics of plants and animals, to produce 128 medically important products and to treat genetic disorders in humans TYPES: A. CLONING – the process extracting or isolating the chromosomes of one organism from the nucleus of the cell, synthesizing the DNA, then inserting it to another organism of the same species to produce the desired copies or CLONES B. EMBRYO TRANSPLANT – the removal of an embryo from one female organism (or a test tube) to place the embryo in another female organism EXAMPLE: TEST TUBE BABIES - are form of embryo transplant. The donor sperm is combined with a recipient egg and fertilization occurs in vitro (in glass). The fertilized egg is then inserted into the female uterus by syringe. C. ARTIFICIAL INSEMINATION – the process of mechanically placing the sperm in the vagina or uterus, after which fertilization is allowed to occur naturally - used in animal breeding - means to preserve some animal species in danger of extinction -solved the problem of infertility in human 129 D. RECOMBINANT DNA – “GENE SPLICING TECHNOLOGY” -the product of genetic engineering in which pieces or small fragments of DNA from plant or animal cells are combined to form new sequences Example. PLASMID microorganisms/bacteria TECHNOLOGY in PRODUCTS FROM GENETICALLY ENGINEERED MICROBES INTERFERONS – group of antiviral compounds that may treat few forms of cancer (skin cancer) like melanoma and leukemia -fight viral infection -boost the immune system -relieve rheumatoid arthritis INSULIN GROWTH HORMONE PLASMINOGEN ACTIVATOR TUMOR NECROSIS FACTOR INTERLEUKIN 2 ENZYMES 130 CLASSIFICATION AND NOMENCLATURE IMPORTANT TERMS: SYSTEMATICS – the study of the diversity of organisms at all levels of organizations -includes the taxonomy and classification of organisms TAXONOMY – deals with identification and naming (nomenclature) of organisms PHYLOGENY – the evolutionary history of a group of organism; the scientific basis of classification IDENTIFICATION – recognition of certain distinguishing characters of the plant specimen; results in the comparison of the specimen with similar specimens DESCRIPTIONS –the listing of features/characters of the plant specimen CLASSIFICATION –arrangements of plants into groups having common characteristics -results in the placing of plants into a hierarchy of ranks or categories NOMENCLATURE –the orderly application of binomial names to a particular taxon CARL VON LINNE (1707-1778) LINNAEUS” known as the proponent of Taxonomy 131 “CAROLUS introduced the use of Binomial System of Nomenclature for all species published 2-volume set of Species Plantarum in 1753 which included 7,300 kinds of plants TAXONOMIC CATEGORIES The group of organisms in a particular category is called taxon Each of the category could be subdivided into three additional categories as in SUPERORDER, ORDER, SUBORDER, and INFRAORDER THE SEVEN OBLIGATORY HIERARCHICAL CATEGORIES KINGDOM – maybe composed of several phyla or division PHYLUM – (Division in plants) maybe composed of several classes CLASS – maybe composed of several orders ORDER –maybe composed of several families FAMILY – maybe composed of several genera GENUS – maybe composed of several species SPECIES- maybe composed of several subspecies or varities 132 EXAMPLE/CLASSIFICATION OF HUMAN: KINGDOM Animalia PHYLUM Chordata CLASS Mammalia ORDER Primates FAMILY Hominidae GENUS Homo SPECIES sapiens SCIENTIFIC NAME: HOMO SAPIENS SCIENTIFIC NAME A binomial nomenclature given to a particular species Composed of the Generic name (genus) and species epithet Should be treated in Latin or should be Latinized Should be underlined separately or italized Latin is used to avoid jealousy among scientific community Should follow the rules and recommendations set by the International Code of Botanical/Zoological Nomenclature (ICBN) The universal standard name for any organisms 133 KINGDOM OF ORGANISM I.TWO KINGDOM SYSTEM proposed by Aristotle, kingdom Plantae (immobile) and kingdom Animalia (mobile) II. THREE KINGDOM SYSTEM proposed by German scientist, Earnst Haeckel (1866), adding kingdom Protista for unicellular organisms III. FOUR KINGDOM SYSTEM proposed by H.F. Copeland (1938) adding kingdom Mychota (Monera) for the Prokaryotes and renamed Prostita to Protoctista for the Protozoan and Fungi IV. FIVE KINGDOM SYSTEM proposed by R.H. Whittaker (1957) revised the earlier arrangements into 5 kingdoms MONERA, PROTISTA, FUNGI, PLANTAE AND ANIMALIA unnatural and not based on phylogeny criteria used in classification are types of cells (prokaryote and eukaryote), mode of nutrition (autotrophs and heterotrophs), motility and life cycles most commonly used, especially for academic purposes V. EIGHT KINGDOM SYSTEM proposed by American Molecular Biologist, C. Woese (1990) and introduced the concept of domain based on phylogenetic evolution and molecular data 134 organisms are arranged in phyletic sequence divided into three domains, BACTERIA, ARCHAEA AND EUKARYA DOMAIN I. Kingdom I. DOMAIN II. Kingdom 2. DOMAIN III. Kingdom 3 Kingdom 4 Kingdom 5 Kingdom 6 Kingdom 7 Kingdom 8 BACTERIA Eubacteria (typical bacteria) ARCHAEA Archaeabacteria (Achaic bacteria) EUKARYA Archezoa (ancient animals) Protista (protozoans) Chromista (brown algae) Plantae (red and green algae) and plants Fungi Animalia VIRUSES – exceptional form of living things - not included in the kingdom of classification - borderline forms between living and non-living things 135 I. KINGDOM: MONERA A. PHYLUM: SCHIZOPHYTA (BACTERIA) the only representative of kingdom Monera most abundant and most common organisms on earth believed to be the first form of life on earth no membrane-surrounded nucleus (prokaryotes) the simplest and smallest living organisms. less than 1µ (micron) or 0.01mm in length TYPES OF BACTERIAL CELLS A. AS TO SHAPE 1. Coccus (cocci) – sphere shaped or globular 2. Baccilus (bacilli) – cylindrical or rod shaped 3. Sprillum (spirilla) – spiral or corkscrew shaped B. AS TO GRAM POSITIVENESS (cell wall components) 1. Gram positive bacteria – colored violet after staining with gram-staining solution with murein in cell wall 2. Gram negative bacteria – colored red after staining with gram staining solution no murein the cell wall 136 C. AS TO NUTRITIONAL REQUIREMENTS 1. Lithotrophs (Antotrophs) – organisms that depend on inorganic matter for growth 2. Organotrophs (Heterotrophs) organisms that depend on organic matter fro growth D. AS TO OXYGEN REQUIREMENTS 1. AEROBES a. Obligate aerobes – when they survive mainly in the presence of atmospheric oxygen b. Facultative aerobe – basically anaerobic organisms but are able to survive in the presence of atmospheric oxygen 2. ANAEROBES a. Obligate anaerobes – survive mainly in the absence of atmospheric oxygen b. Facultative anaerobes – basically aerobes but can survive even in the absence of atmospheric oxygen 3. MICROAEROPHILES – organisms that survive in the presence of small amount of atmospheric oxygen E. AS TO THERMAL REQUIREMENTS 1. Psychrophilic – organisms grow at a temperature below 100C; cold-loving organisms 2. Mesophilic – organisms grow around 37oC 3. Thermophilic – grow at 45oC or more most organisms grow as mesophiles. 137 F. AS TO PH REQUIREMENT 1. Acidophilic – organisms prefer an acidic environment 2. Basophilic - organisms prefer an alkaline environment BACTERIA maybe 1. Pathogenic – related to the production of disease process in man 2. Non-pathogenic – do not caused diseases in man SAPROPHYTIC – as saprophytes they are involved in the following activities: a. decomposition of dead matter b. soil fertilization (nitrogen cycle) c. sewage purification d. useful in industrial processes e. useful in food manufacture f. used in genetic engineering for the production of some useful substances such as “interferons” insulin, growth hormones and others g. some are agents of diseases like… cholera diphtheria tuberculosis abscesses bubonic plague leprosy bacterial dysentery whooping cough gonorrhea pneumonia (strep.) U.T.I. tetanus 138 B. PHYLUM: CYANOPHYTA (Blue-green algae) most primitive kind of algae commonly called “seeweed” or “water moss” closely related to bacteria considered autotrophs or self-feeders contains chlorophyll A (green pigment), carotene and xanthophylls (yellow), phycocyanin (blue), phycoerythrin (red) 139 II. KINGDOM: PROTISTA mostly unicellular; live in fresh water, salt water or moist places free-living or parasitic cells have nuclei (eukaryotic type) live singly or colonial: each cell colony can perform all life processes divided into plant-like protests (ALGAE) and animallike protists (PROTOZOA) A. ALGAL PROTISTS aquatic organisms capable of photosynthesis part of phytoplanktons possess chloroplast and cell wall store reserve food usually unicellular, some are colonial and multicellular classified according to their color: green, brown, golden brown and red algae 1. PHYLUM CHLOROPHYTA (green algae) mostly marine; closely related to the first plants; possess clorophylls a and b stored reserve food as starch inside the chloroplast may reproduce sexually and asexually 140 Examples: Spirogyra, volvox, ulva, oedegonium 2. PHYLUM PHAEOPHYTA (brown algae) grow along the shoreline commonly called as “seeweeds” possess chlorophyll a and b, and FUCOXANTHIN store reserve food as laminarin source of ALGIN, a pectin-like material that is added to ice cream and other cream products for smooth consistency Examples: Laminaria, focus, sargassum 3. PHYLUM CHRYSOPHYTA (golden brown, yellow green, diatoms) the most numerous unicellular algae in the oceans and in freshwater habitats contains chlorophyll a, carotenes and xanthophylls cell wall has an outer layer of silica important source of food and oxygen Examples: Vaucheria, synura pinnularia, navicula (diatoms) 4. PHYLUM PYRROPHYTA (Dinoflagellates) bounded by protective cellulose plants most have 2 flagella 141 possess chlorophyll a and c, carotenes and fucoxanthin (yellow brown pigment) extremely numerous in the oceans frequently color coastal waters orange, red or brown as indications of RED TIDES they produce neurotoxin that can cause paralysis of respiratory muscles some are luminescent called “fire plants” Examples: Gymnodinium, Gonyaulax 5. PHYLUM RHODOPHYTA (red algae) multicellular eukaryotes live in warmer sea water possess chlorophyll a and phycobilins reserve food is glycogen – like floridean starch source of agar used commercially to make capsules for vitamins and drugs used as base materials for cosmetics used as culture medium for bacteria and in food preparation (baking, dessert, jellies) Examples: Halymenia, Galaxaura 6. PHYLUM EUGLENOPHYTA (Euglenoid flagelattes) unicellular aquatic protests about 500 species possess one to several flagella show both the characteristics of plants and animals 142 plant-like because they have chloroplast that contains chlorophyll and can manufacture food by photosynthesis (autotrophs) animal-like because they lack cell wall -motile organisms; can also ingest food particles (heterotrophs) Example: Euglena – fresh water green flagellates, indicator species of organic pollution some are also found in marine waters and mud B. ANIMAL PROTISTS (PROTOZOANS) mostly motile, unicellular, colonial, multi-cellular organisms usually aquatic, part of zooplanktons that fed on phytoplanktons considered heterotrophic, some are holozoic saprotrophic, parasitic classified according to their locomotory organs pseudopods, cilia, flagella 1. PHYLUM SARCODINA (Rhizopods/amoeboids) about 8,000 species float or creep about in water a thin cell membrane surrounds the protoplasm of the cell body 143 with protoplasmic extension called…PSEUDOPODIA OR “FALSE FEET” for movement and capturing the food (engulf their prey) some may cause disease such as Entamoeba histolytica, a parasite in human intestine that causes amoebic dysentery Example: Amoeba 2. PHYLUM CILIOPHORA (ciliates) about 5,000 species move by means of hairlike processes called “CILIA” most are holozoic (engulf whole food) divide by transverse binary fission retain a more or less permanent shape because of a (hard covering) known as PELLIOLE differ from others by having 2 types of nuclei the large macronucleus that controls the normal metabolism of the cell the small micronuclei concerned with reproduction Example: Paramecium, Balantidium coli 3. PHYLUM SPOROZOA (sporozoans) about 2,000 species all parasitic with complicated life cycle not capable of locomotion (non motile) feed on protoplasm and body fluids of their host 144 Example: Plasmodium Plasmodium vivax – causative agent of malaria from the bite of female Anopheles mosquito “Anopheles minismus flavirostvis” - injects sporozoites in the blood of a person, enters the blood stream, destroys the RBC - brings chills and high fever 4. PHYLUM ZOOMASTIGINA (zooflagellates) about 1,200 species move by means of flagella unicellular, some are colonial, others are parasitic mostly mutualistic or live in symbiotic relationships with other animals that may cause human diseases Example:Trichomonas, Trypanosoma, Giardia RELEVANCE/ SIGNIFICANCE: algal protists (algae) supplied food and oxygen to aquatic animals 70 species of algae are edible or can be eaten by man like… the ULVA (see lettuce), CAVLERPA or (ar – arosep), CODIUM some have industrial uses - brown alga – algin used in making ice cream - red alga – carrageenan, agar are used as stabilizer in food, paints, cosmetics, pharmaceuticals 145 some species are harmful - Dinoflagellates are the cause of RED TIDE Animal Protists (protozoans) important in the hydrosphere serve as indispensable link in the food chain some species cause serious diseases in man - malaria (Plasmodium) - amoebiasis (Entamoeba) - Fatal sleeping sickness (Trypanosoma) 146 III. KINGDOM FUNGI multicellular eukaryotes about 80,000 species heterotrophs organisms, cannot produce their own organic materials, lack chlorophyll obtain nutrients from dead organic matter (decomposers) so they can be (SAPROPHYTES) or from other living organisms (PARASITIC) grow best in moist, warm, organic rich environments optimum pH for most species is 5.6 mostly aerobic energy reserve is glycogen reproduce by formation of sexual or asexual spores or by fragmentation of the hypha this includes the mushrooms, bracket fungi, bread mold, yeasts, mildews, slime molds MORPHOLOGY/ BODY STRUCTURES: 1. Thallus – main body of the fungi - actively growing vegetative portion 2. Hypha – filamentous or thread like structure that grows from the body 3. Mycelium – a group of hypha 4. Spores – non- motile structure produce by fungi during sexual and asexual reproduction 147 CLASSIFICATION: about 1.5 million species of fungi are in the world 1. PHYLUM BASIDIOMYCOTA (club fungi) the most advance group, about 1,500 species produce spores on a special structure called the “Basidium” Example: mushrooms, bracket fungi, rusts that infect some trees and smuts that infect corn 2. PHYLUM ZYGOMYCOTA (conjugation fungi) the simplest form of fungi, about 1,000 species reproduce by conjugation resulting into a zygosphore, a fungus which attacks fruits the most popular species of this group is the Example: bread mold (Rhizopus) 3. PHYLUM ASCOMYTA (sac fungi) the largest division of fungi, about 15,000 species asexual reproduction is more common Example: yeast, blue – green molds, morels and powdery mildews which attack plants *yeast are found in decaying fruits, grains and other food, a little larger than bacteria used in making of wine, bread (dough nut) 4. PHYLUM OOMYCOTA (water molds) about 500 species 148 parasitize fishes and same food crops found in water or moist habitats cell wall is made up of cellulose instead of chitin Example: Saprolegnia – parasitizes fishes Peronospora – blue mold of tobacco 5. PHYLUM DEUTEROMYCOTA (Imperfect fungi) always reproduce asexually by coniodiospores no sexual reproduction unlike the other 5 phyla include some important fungi/ parasites that causes athlete’s foot and ringworm Example: Penicillium – the source of penicillin Candida – causes yeast infection 6. PHYLUM MYXOMYCOTA (slime molds) about 400 species resemble giant amoebas because they move over decaying organic matter by amoeboid movement seen on rotting logs, decaying leaves or moist soil the thallus of this mold is called “PLASMODIUM” Example: Dictyostelium, Physarum 149 IV. KINGDOM PLANTAE (plants) multicellular eukaryotic organisms mostly autotrophic (major producer in the world) non motile organisms over 300,000 species with cell wall made up of cellulose substance reproduce by sexual or asexual means with chlorophyll pigment needed in the process of photosynthesis CLASSIFICATION: I. DIVISION BRYOPHYTA (Bryophytes) non vascular plants or lack conducting tissues (no xylem and phloem) the first plants to live on land small multicellular plants lack true roots, stems, and leaves mostly terrestrial occurring in moist places, like in moist soil, rocks, cement fences and walls, tree trunks, forest floors, banks of streams and others THREE MAJOR GROUPS: 1. CLASS MUSCI (true mosses) about 4 cm. long with tiny, spirally arranged green leaves 150 grow as a colony forming green mats that cover moist and shady soil, rocks, cement structure, tree trunks the most common or popular mosses in our country is the Sphagnum or “peat moss” that used as planting medium for potted plants because it can hold/ absorbs great amount of water 2. CLASS HEPATICAE (Liver worts) with flat, leathery thallus that shaped like the liver *wort – “herb” grows in areas where mosses are found green in color about 1 cm. wide the most common genera are the Marchantia and Porella 3. CLASSS ANTHOCEROTAE (hornworts) looks like a small, flat, green structure about 2 cm. wide with numerous lobes that grows adhering to the ground the most common genus is the Anthroceros II. DIVISION TRACHEOPHYTA (Tracheophytes) vascular plants or with conducting tissues (xylem and phloem) the dominant land plants that ranges from herbs, shrubs and trees 151 generally grows taller and wider than bryophytes because of the presence of xylem and phloem can be seed bearers or non seed bearers seed bearers can be flowering (Angiosperm) or non flowering (Gymnosperm) the body is divided into different organs…(the roots, stems, leaves, flowers) 1. SUBDIVISION PSILOPHYTINA (Psilopsids) non seed bearing plant with body axis extending down ward into the soil leaves and roots are absent; usually small plant Example: Psilotum 2. SUBDIVISION LYCOPHYTINA (Clubmosses) non seed bearing, usually small with simple irregularly arranged leaves dominant land plant group in the swamps that covered the earth about 300 million yrs. Age Example: Lycopodium, Selaginella 3. SUBDIVISION SPHENOPHYTINA (horse tails) non seed bearing, known mostly as fossils generally small herbaceous plants form a strobilus or cone that resembles a horse tail Example: Equisetum 152 4. SUBDIVISION PTEROPHYTINA (Fern) most extensive and numerous of the seedless plants comprising more than 12,000 species the leaves are more broad and more vascularized than the others commonly grown in gardens for their beautiful leaves Example: ferns 5. SUBDIVISION SPERMATOPHYTINA (seed plants) the seedbearing plants with well developed vascular tissues undergo pollination process (cross/ self) group into gymnosperm and angiosperm based on how the seeds are borne A. GYMNOSPERM (naked seeds) non flowering seeds are not surrounded by a mature ovary wall, (exposed) seeds are borne on the surface of cones “cone bearing plants” 1. CLASS CYCADOPSIDA (cycads) dioecious plants with palmlike or fern like form produce strobili or cones grow in warm climates abundant during the age of dinosaurs locally known as the “PITOGO” or sago palm 153 2. CLASS GINKGOPSIDA (ginkgoes) dioecious plants with tree habit have strap – shaped or fan – shaped leaves with catkin like strobili common as an urban tree resistance to air pollution survived today as a single specie , the ginkgo or the “maiden hair tree” 3. CLASS CONIFEROPSIDA (conifers) monoecious plants most of which are trees with typical scale like or needle like leaves that are usually evergreen (pine tree) the most conspicuous of the gymnosperm especially in colder climates most common local species of pines are Pinus insularis and Pinus merkusli with both male and female cones in the same tree 4. CLASS GNETOPSIDA (gnetopsids) mostly large and coarse plants, frequently with thick unbranched stem bearing crown of palm like leaves tropical dessert plants; extinct Example: Gnetum, Ephedra, Welwitschia B. ANGIOSPERMS (flowering plants) constitute the dominant terrestrial vegetations close to 219,300 species of flowering plants 154 with seeds contained or enclosed within the ovary of the flower includes a great variety of shrubs, trees and herbaceous plants can grow as annuals, biennials and perennials CLASS MAGNOLIOPSIDA SUBCLASS MONOCOTYLEDONEAE (monocot) plants with only one cotyledon or (seed leaves) Example: rice, corn, lilies SUBCLASS DICOTYLEDONEAE (dicot) Plants with two cotyledons Example: fruit bearing trees like mango, avocado,santol flowers like rose, gumamela 155 V. KINGDOM ANIMALIA all animals are many-celled the cells are differentiated to form specialized tissues tissues are usually grouped to form organs and the organs to organ systems most animal cells have a nucleus and organelles such as mitochondria, golgi bodies, lysosomes and robosomes animal cells are bounded by a plasma membrane they are not rigid like plant cells. Animals are heterotrophic they feed on other organisms most animals are motile and can move from place to place all animals are capable of sexual reproduction although some reproduce asexually 1. Phylum Porifera (Sponges) Some sponges are the simplest of the animals. The body is perforated with minute pores called ostia for the entrance of water into a central cavity, the spongocoel. The larger openings, the oscular, are for the exit of water. Sponges have no organs, only tissues. 156 Digestion takes place within the cell called intercellular digestion. Flagellated cells circulate the water in the spongocoel. The skeleton is in the form of microscopic spicules or a network of sponging or both. The sponge is attached to the sea bottom or to rocks by means of a stolon. a. Class Calcarea Calcareous sponges Spicules limy (CaCO3). 1-, 3- or 4-rayed; body surface bristly; marine in shallow waters. Example: Grantia b. Class Hexactinellida. Glass sponges. Spicules siliceous, 6-rayed; marine, at 300 feet or deeper. Example: Venus’ flower basket. c. Class Demospongiae. Skeleton siliceous; mostly marine. Example: bath sponge. d. Class Sclerospongiae. Coralline sponges Massive skeleton of calcium carbonate 157 Example: Merlia. 2. Phylum Coelenterata (Cnidaria) Coelenterates Most coelenterates are colorful so that most of the time they are referred to as “flower animals”. These are the animals that fascinate scuba divers for they abound in the sea bottom. The body of the coelenterates is radially symmetrical. The digestive tube is in the form of a hollow, gastrovascular cavity. There is no anus. Hence the digestive tube is incomplete. Their mouth is surrounded with tentacles which are provided with stinging cells or nematocysts. a. Class Hydrozoa. Hydroids. Mouth opens directly into a digestive cavity that lacks partitions; hydroid stage usually in colonies; medusa with velum. Example: Hydra (freshwater polyp) b. Class Scyphozoa. Jellyfishes. Small to large medusae, chiefly of gelatinous mesoglae, and of bell or umbrella shape, 158 margined with tentacles; polyp stage minute or none Example: Acrometoides (a common specimen found in Manila bay) c. Class Anthozoa. Sea anemones, corals, etc. All polyps (no medusae); a flat oral disk with tentacles; digestive cavity divided by radial partitions. Examples: sea anemone, sea fan, staghorn coral, organ pipe coral and black coral. 3. Phylum Platyhelminthes (Flatworms) These are the unsegmented worms. The body is dorsoventrally flattened and bilaterally symmetrical. The digestive tube is incomplete because there is no anus. Flatworms are either free-living or parasitic. They are usually hemaproditic. a. Class Turbellaria (Free-living flatworms) their body is ribbonlike to dislike. they have no hooks or suckers. they are either marine, freshwater or terrestrial. Example: Planaria 159 b. Class Trematoda (Flukes) their body is often leaflike, with thick cuticle and no cilia. some have ventral suckers or hooks or both. all are parasitic. Example: Fasciola (liver fluke) c. Class Cestiodea. (Tapeworms) their body is flat, narrow, elongate, comprising of a scolex. they make use of suckers or hooks or both for attachments. all are parasitic. Example: Taenia (pork tapeworm) 4. Phylum Nematoda. (Roundworms) their body is cylindrical. there are about 10,000 species of these worms. some feed on decaying matter and are therefore scavengers. most species are parasitic on plants and animals a few are free-living. a typical example is Ascaris lumbricoides, eelworm of man. 160 the sexes are separate. the female looks differently from the male and are therefore sexually dimorphic. the body is slender and cylindrical, tapering at both ends. it is covered by a smooth, tough and elastic cuticle, bearing minute striations. the female is larger than the male. turbatrix aceti, vinegarell, is the most familiar example of a free-living nematode. this is seen as the minute organism on the surface of naturally fermented vinegar. these are non-pathogenic forms. parasitic forms include hookworms, whipworms and pinworms. 5. Phylum Rotifera (Wheel Animalcules) They are called wheel animalcules because of two groups of cilia which beat the water like a pair of spinning wheels. They are microscopic forms found in freshwater ponds, streams, muddy ditches and street gutters. They feed on unicellular forms with the use of the wheel organ. Example: Hydatina. 161 6. Phylum Bryozoa (Moss Animals) They are called moss animals because they are similar in appearance to bryophytes. All bryozoans are aquatic and most are marine. They are colonial most are attached or sessile. The body is cylindrical with the mouth surrounded by ciliated tentacles. The digestive system is complete. Example: Bugula. 7. Phylum Mollusca (Mollusks) Their body is radially symmetrical, usually no segmentation. Their soft bodies are covered by a mantle that usually secretes a limy shell. They usually have an anterior head and a ventral muscular foot for locomotion. The digestive tract is complete. Sexes are usually separate. Some are found in saltwater, others in freshwater and some on land. 162 a. Class Polyplacophora. Chitons Their body is usually elliptical. They have shells made up of eight plates. They are marine type. Example: Chiton. b. Class Scaphopoda. Tooth shells They have a tubular shell open at both ends and shaped like an elephant’s tusks. Example: Dentalium. c. Class Gastropoda. Univalve mollusks. They are known as stomach-footed mollusks. The foot is long and flat and lies under the belly. It is used for creeping, hence, the name stomachfooted or gastropods. They are also called univalves of the presence of single shell which may be spiral or not. The heads is distinct, with one or two pairs of tentacles. Example: snail, slug, abalo and cowry. d. Class Bivalvia. Bivalve mollusks. They are known as the hatchet-footed mollusks. The foot is wedge-shaped and is used for digging. The shell is made up of two valves, hence the name, bivalves. 163 They have no head or jaws. Examples: clam, mussel and oyster. e. Class Cephalopoda. Squids,octopus, etc. They are known as the head-footed mollusks because the foot is in the form of tentacles attached to the head, hence the name head-footed. The foot is used for food-getting. Eyes are larger and prominent. The shell is internal as in squids or external as in the nautili. Examples: squid, octopus (devilfish) and nautilus. 8. Phylum Annelida (Segmented Worms) There are about 10,000 anneloids. The unique feature of this group is segmentation. The body is divided into similar ringlike segments or somites. They have a complete digestive tract. They are found in freshwater, and in moist and damp places, in seashores or in burrows. a. Class Polychaeta. Sandworms, tubeworms, etc. Segmentation is conspicuous, with many somites having lateral projections that bear numerous setae. 164 The head is evident, with tentacles. Sexes are usually separate. They are chiefly marine. Example: clamworm. b. Class Oligochaeta. Earthworms, etc. Segmentation is also conspicuous. They have no head or parapodia. Their setae are usually few per somite. They are found in freshwaters and moist soil. Example: Pheretima benguetensis (common local earthworm). c. Class Hirudinea. Leeches. Their bodies are flat. The somites are inconspicuous, each is divided internally into several annuli. They have no setae or parapodia. The first and last body segments are modified to form suckers used for locomotion and attachment. Example: Hirudo (leech) 9. Phylum Arthropoda(Artropods) This is the largest of all phyla. They are found in almost any environment-on land, underground, in water, on plants, on animals and inside animals. 165 The anthropods are joint-footed with numerous paired appendages. The body is covered by a chitinous exoskeleton. Their digestive tract is complete. Sexes are usually separate. a. Class Merostomata. The cephalothorax broadly joined to abdomen on which are five or six pairs of appendages. They are aquatic type. Example: horseshoe crab b. Class Arachnida. Arachnids. Their abdomen lacks locomotor appendages. They are usually terestial. Examples: tick, scorpion, head louse, spider, and itch mite. c. Class Crustacea. Crustaceans. They have two pairs of antennae, one pair of jaws, and two pair of maxillae. The body is divided into a cephalothorax and abdomen. The cephalothorax is formed by the fusion of the head and thorax. Most of them are aquatic. 166 Examples: crayfishes, lobster, crab, shrimp and prawn. d. Class Insecta. Insects. These animals have distinct head, thorax and abdomen. The thorax typically with three pairs of legs and two pairs of wings. They are mainly terrestrial. Examples: grasshopper, fly, butterfly and mosquito. e. Class Chilophoda. Centipedes. Their body is long, flattened and has 15 to 181 somites, each with a pair of legs. They have one long pair of antennae. Centipedes are predators. They are terrestrial. Example: Scolopendra (centipede) f. Class Diplopoda. Millipedes. Their body is cylindrical and not flattened. The body is divided into a head, thorax and abdomen. The abdomen has 9 to more than 100 double somites, each with pairs of legs. They are terrestrial. Example: Julus (millipede) 167 10. Phylum Echinodermata (Echinoderms) The body of the echinoderms is radially symmetrical and has no segmentation. Characteristic of the group is the presence of spines that are either minute or large covering of the body. The body is supported by a skeleton of bony plates. Another unique feature of the group is watervascular system of circulation. Water, not blood, is issued for circulation. a. Class Crinoidea. Sea lilies, feather stars. They are flower like. The body is small and cup-shaped, which is called calyx. Attached to it are five flexible arms. Each arm branches into two, each bearing slender lateral pinnules. Thus, the arms resemble feathers. Example: Antedon. b. Class Asteroidea. Starfishes or sea stars. Their body is star-shaped or pentagonal with five two fifty arms or rays not sharply distinct from central disk. 168 Their skeleton is flexible, usually with short spines. Example: Asterias c. Class Ophiuroidea. Brittle stars. They have five long, segmented arms that move like snakes, hence, they are called snake star. The arms easily break when handled, hence, the name brittle star. It has great power of regeneration, the ability to replace lost parts. Example: Ophiura (brittle star) d. Class Echinoidea. Sea urchins, sand dollars. Their body may be rounded or ovoid; some are flattened, others are globular. They have no projecting arms. The body is covered with small or large spines. Example: Strongylocentrotus (sea urchin); Dendraster (sand dollar) e. Class Holothuroidea. Sea cucumbers. Their body is bilaterally symmetrical. They have no arms. 169 The mouth is on one end surrounded by retractile tentacles. The body is elongated or wormlike. Example: Holothuria 11. Phylum Chordata (Chordates) There are three unique characteristics of this phylum: they have notochord gill slits hollow nerve chord. Protochordates The protochordates are the invertebrate chordates or chordates without vertebral column. They look more like primitive invertebrates rather than chordates. However, they share the three unique characteristics of chordates, thus suggesting a biological relationship or kinship with the chordates. Example: Amphioxus (lancelet) Vertebrate Chordates There are about 49,000 species of vertebrates inhabiting the seas, freshwater, and land. 170 Of these, 30,000 species are fishes, the others are terrestrial forms. However, the amphibians, some reptiles and some mammals share the waters with the fishes. a. Class Cyclostomata. Lampreys. Their body is cylindrical, slender and with median fins only. Their mouth is always open because they have no jaws. They are called cyclostomes (circular mouth) or jawless vertebrates. Example: Petromyzon (lamprey) b. Class Chondrichthyes. Cartilaginous fishes. These fishes have skeletons of cartilage instead of bone. All species breathe through their gills. The gill slits are exposed and seen at the sides of the head. The skin is covered with placoid scales. Examples: Squalus(shark);Raja (ray) c. Class Osteichthyes. Bony fishes. These fishes have skeletons made chiefly of bone. All species breathe through their gills. 171 The gill slits are covered by an operculum or gill cover. The scales are usually cycloid and large. Examples: salmon, milkfish and lungfishes d. Class Amphibia. Amphibians. Most amphibians live partly on land and partly in water. As a result, they have legs instead of fins and lungs instead of gills in the adult. However, their larvae are aquatic and breathe through the gills. Examples: frogs, toads, salamanders and mud puppies e. Class Reptilia. Reptiles. These animals have dry skin covered with horny scales (hardened skin). They breathe through their lungs. Most of them are terrestrial and only a few are aquatic. They lay large eggs covered by a soft shell. Examples: tuatara, lizards, snakes, crocodile and alligator 172 f.Class Aves. Birds. Birds are the only group of vertebrates (excluding bats) capable of true flight. This is the only group with feathers. They breathe through the lungs. They lay eggs covered by a hard shell. Birds are warm-blooded or homeothermous. Most of them are terrestrial but some are aquatic. Some birds are unable to fly like the ostriches. Examples: duck, crow, and sparrow g. Class Mammalia. Mammals. This is the only group of vertebrates with hair. They gave birth to their young alive. They nurse their young with milk coming from their mammary glands. They are homeothermous or warm-blooded. Examples: man, kangaroo, horse, pig, cat, dog, cow, whale, bat, rabbit, fox, monkey, bear and others. 173 ECOSYSTEMS DEFINITION OF TERMS Ecology (Greek, oikos, house or home) – the study of the interactions of organisms among themselves and with the physical environment Population – all members of the same species inhabiting a particular area Community – all the populations found in a particular area Ecosystem – community and its physical environment, characterized by a flow of energy and a cycle of inorganic nutrients Biosphere – region of the earth (atmosphere, hydrosphere, lithosphere) where organisms exist Succession – progressive change in plant and animal life of an area Habitat – place where an organism lives and able to survive and reproduce Biome – a natural unit of living and non – living components that interact to form a stable system in which the exchange of materials follow a circular path Niche – functional role and position of an organism in the ecosystem 174 Pollution – any contamination of the environment; any process by which humans destroy the environment THE ECOSYSTEM Components Abiotic Components the non – living component the physical environment includes soil, water, light, inorganic nutrients, and weather conditions Biotic Components the living components composed of a habitat and a niche Different Roles (niche) of the Biotic Components Producers the autotrophic organisms capable of producing their own food; could be chemoautotrophs (bacteria), obtaining energy by oxidizing inorganic compounds to synthesize carbohydrates, or a photoautotrophs (plants), obtaining energy from light to synthesize carbohydrates 175 Consumers the heterotrophic organisms that eat available food classified into three groups: 1. herbivores (primary consumers) feed directly on green plants 2. carnivores (secondary or tertiary consumers) feed on other animals 3. omnivores feed on both plants and animals Decomposers the heterotrophic organisms that break down detritus, non – living organic matter, to inorganic matter, to be used again by the producers AQUATIC ECOSYSTEM Classification of Organisms Present in Aquatic Ecosystem 1. benthos, resting or living at the bottom 2. periphyton, attached or clinging on stems or leaves of rooted plants or other surfaces projecting above the bottom 3. plankton, floating, dependent on the current 4. nektons, swimming can navigate at will 5. neuston, resting or swimming on the surface Freshwater Ecosystems occupy relatively small portion of earth’s surface 176 the most convenient and cheapest source of water for domestic and industrial needs the study of freshwater habitats is called limnology Types of Freshwater Ecosystems 1. Lentic or standing water – ponds and lakes Subdivided into three major zones: a. littoral zone, shallow water region with light penetration up to the bottom b. limnetic zone, open water zone up to the depth of effective light penetration 2. Lotic or running water – rivers and streams Subdivided into two major zones: a. Rapid zone, shallow water where velocity of current is great enough to keep the bottom clear of silt and other loose materials providing a firm substrate. b. pool zone, deeper water where velocity of current is reduced and silt and other loose materials settle to the bottom providing a soft substrate Marine Ecosystem (Ocean) occupy 70% of the earth’s surface the great reservoir of living things and nutrients the study of marine habitat is called oceanography 177 Divisions of the Ocean 1. pelagic division includes the open sea a. neritic province, shallow water above the continental shelf, with more nutrients and organisms because sunlight penetrates the waters up to the bottom Subdivided into three zones: supratidal (above the high tide mark) intertidal (between high and low tide) subtidal (below the low tide mark) b. oceanic province, the region of the open sea beyond the continental shelf, above the oceanic basins Subdivided into four zones: euphotic zone, (depth up to 120 m, upper part of the ocean into which light can penetrate) bathyal zone (depth up to 3,000 m, lower part of the ocean in complete darkness) abyssal zone (depth up to 4,000 m) hadal zone (depth betond 4,000 m) 2. benthic division includes the depths of the sea Subdivided into three zones: 178 a. continental shelf in the sublittoral shelf, the floor of the neritic province b. continental slope in the bathyal zone, a sudden drop of the ocean floor from the continental shelf up to the abyssal plain c. abyssal plain in the abyssal zone, the ocean floor of the abyssal zone, interrupted by many underwater mountain chains called oceanic ridges TERRESTIAL ECOSYSTEM the most variable in terms of time and geography has the largest plant biomass Types of terrestrial biomes Tundra -located nearest to the polar region -vegetation includes lichens, mosses, grasses and lowgrowing shrubs -few animals adapted to cool temperature live in the tundra, polar bears, caribou, and musk ox; during summer, insects and birds migrate the biome Taiga -located just below the tundra extending in a broad belt across northern Eurasia and North America -composed of coniferous forest dominated by conebearing trees such as spruce, fir and pine 179 -birds, bears, deer, moose, beavers, wolves and even mountain lion could be found Temperate Deciduous Forest -located south of the taiga in eastern North America, eastern Asia and much of Europe -with moderate climate and relative high rainfall -dominated by deciduous trees, oak, beech and maple -amphibians and reptiles are found, together with some other vertebrates as squirrels, rabbits, foxes, deer and bears Tropical Rain Forest -located near the equator -considered to be the richest biome in terms of number and abundance of species -has a complex structure, with many levels of life, from simplest bryophytes and epiphytes to woody vines and giant trees -insects, amphibians, reptile birds, and mammals are well represented -characteristic of Philippine forest Grassland (Savanna) -located in regions where a relatively cool dry season is followed by a hot, rainy one 180 -dominated by grasses that can adapt to changing temperature and can tolerate high degree of grazing, flooding, drought and sometimes fire -supports large group of grazers (zebras and wildebeests) and browsers(giraffes), and predators(cheetahs and lions) Deserts -located at about 30o, in Northern and Southern hemispheres -support organisms adapted to arid conditions -plants are succulents, or shrubs with woody stems and small leaves -animals require little water or are adapted in storing water such as kangaroo rat, roadrunner, insects, lizards and snakes SPECIES INTERACTIONS Symbiotic Relationships refers to interactions in which there is a close relationship between members of two populations Parasitism -one species(parasite) benefits in terms of growth and reproduction to the harm of the other species(host) -tapeworm(parasite) and cow or pig(hosts), mites and dog 181 Commensalism -one species is benefited and the other is neither harmed nor benefited -sucker fish and shark, crane and carabao Mutualism -both species benefit in terms of growth and reproduction; -lichens(fungi and algae), termites and protest Predation one species(predator) uses the other(prey) as a food source ther must be an act of killing lioness(predator) and zebra(prey), eagle and chicken SUMMARY Ecology deals with the study of interrelationships between living organisms and the non-living factors in the environment, which may be affecting them. An ecosystem is an interacting system between the community and its abiotic environment. Different interactions occur in the biotic and abiotic components of the community. 182 VIRUSES not considered as true organism due to inability to perform metabolic activities --no metabolic machinery of their own --lack enzyme systems --can’t generate ATP --can’t reproduce themselves called “borderline forms” between living and nonliving things generally smaller than the smallest bacteria (less than 200 µm in diameter) can be purified and crystallized or stored the viral crystals are still infectious when given opportunity to invade the host cells considered as obligate intracellular parasites (can multiply outside a living cell) can infect all sorts of cell but very specific --bacteriophages infect only bacteria --tobacco mosaic virus only in plants --rabies virus only in mammals --human immunodeficiency virus (HIV) only in blood cells --polio virus only in spinal nerve cells --hepatitis virus only in liver cells 183 DISCOVERY OF VIRUS 1884, Louis Pasteur, French Chemist suggested that something smaller than a bacterium was the cause of rabies and gave the name “virus” to it from Latin meaning poison 1892, Dmitri Ivanowsky, Russian biologist studied tobacco mosaic disease and concluded that the disease-causing agent was smaller than any known bacteria and concluded that it was a toxin rather than a microorganism VIRAL STRUCTURE Outer capsid --composed of protein-subunits --maybe surrounded by an outer membranous envelope Inner core of nucleic acid --either DNA or RNA but not both --may contain various proteins (enzymes) needed to produce viral DNA or RNA TYPES OF VIRUS As to host cells 1. Plant viruses – live only in the cells of seed plant, especially flowering plants 2. Human and Animal viruses – live only in human and animal cells 184 3. Bacteriophages – invade only bacterial cells As Agents of diseases 1. Virulent – can cause a disease to the host immediately 2. Temperature – does not cause a disease to the host immediately As to the type of Nucleic Acid 1. DNA VIRUS – contains DNA as the genetic material, can cause sore throat, warts, herpes, chicken fox, fever, small pox, measles 2. RNA VIRUS – contains RNA as the genetic material, cam cause polio, hepatitis, rabies, common cold, influenza, pneumonia, encephalitis 3. RETROVIRUS – contains an enzyme transcriptase, that makes DNA from RNA, the DNA formed makes new RNA which in turn makes new protein to be part of a new virus e.g. HIV VIRUS AIDS (Acquired Immune Deficiency Syndrome) Caused by retrovirus HIV (Human Immunodeficiency Virus) The HIV invades and destroys the body’s white blood cells, particularly (D4 lymphocytes or helper T-cells Could be found in… -blood and semen (high concentration) 185 -vaginal secretion } -saliva, tears, urine} in trace concentration -breast milk } sexually transmitted disease that may be developed after 7 to 11 years of HIV infection TRANSMISSION OF HIV exchange of bodily fluids during sexual intercourse or oral genital contact sharing of blood contaminated needles by IV drug users (intravenous) transfusion of infected blood prenatal transmission from an infected woman to her fetus or infant SARS (Severe Acute Respiratory Syndrome) a condition of unknown etiology that has been described in patients in Asia, North America and Europe a respiratory illness classified as a typical pneumonia or an infection of the respiratory tract that is caused by the corona virus, a virus that causes common colds in human and more serious illness among animals 186 MODE OF TRANSMISSION the main way that SARS is spread is through droplet transmission such droplets maybe produced when someone with SARS sneezes or coughs SARS may also spread through contaminated objects Airborne transmission is most likely possible ORGANS AFFECTED inflation of the lungs and retention of fluid in the lungs tissue damage to the heart muscle and other organs like liver 187 EVOLUTION: I.HISTORY OF THE EARTH (MORE THAN 5 BILLION YEARS OLD) DIVIDED INTO THREE ERAS A. PALEOZOIC (ANCIENT LIFE) -the layers of the rocks and the kind of organisms formed during this time were preserved and recorded *EARLY PALEOZOIC ERA -the fishes were the first vertebrates to appear (no jaws and no paired fins) *MIDDLE PALEOZOIC ERA -Fishes with jaws and paired fins appeared *LATE PALEOZOIC ERA -Amphibians appeared along with some fishes which had fins with lobes that enabled them to propel themselves on land B. MESOZOIC ERA (MIDDLE LIFE) -considered as the great age of the reptiles *EARLY MESOZOIC ERA -dinosuars appeared *MIDDLE MESOZOIC ERA -birds appeared *LATE MESOZOIC ERA -dinosuars start to disappear 188 -as the great reptiles become extinct, the birds took over C. CENOZOIC (RECENT LIFE) -about seven million years ago, the first mammals appeared *EARLY CENOZOIC ERA -during this period, the horse was the first mammal appeared which was only as big as a dog -it had several toes on the foot -gradually became larger, legs became longer and only one toe remained on each foot *some mammals of this era have grown in size tremendously like rhinoceros, elephants, hippopotamus and others *some giant mammals disappeared before theend of the ice ages about 10 million years ago *LATE CENOZOIC ERA - the process of evolution showed that several organisms change new forms, some are lost or become extinct GEOLOGICAL TIMETABLE: Through the ages, the nature has left records of time and change. 189 “GEOLOGICAL CHANGES” -the layers of the earth’s crust were formed by sediment that settle at the bottom of oceans, seas, lakes or other bodies of water -here, the layers are cemented together by chemicals in the water and pressures of overlaying layers forming rock called “sedimentary rocks” -new layers settle above older layers leaving a timetable in rock -the exploration of these layers of sedimentary rocks from more recent layer near the surface to the ancient layer deep into the earth is a journey through million of years of GEOLOGICAL TIME. CONCEPTS OF EVOLUTION: The characteristics of living things change with time. Change in the characteristics of population over the course of many generations The change is directed by Natural Selection process. Changes are in the Genetic make up of the population EVIDENCES OF EVOLUTION FOSSIL – a record of the history of life that shows that organisms have changed over time BIOGEOGRAPHY – the study of the distribution of life form shows that organisms evolve in one locale and then spread to other regions 190 COMPARATIVE ANATOMY – related organisms share a unity of plan COMPARATIVE EMBRYOLOGY – related organisms develop similarly COMPARATIVE BIOCHEMISTRY - almost all living things use the same basic biochemical molecules, including DNA, ATP and many identical enzymes LAMARCK’S THEORY OF EVOLUTION -JEAN BAPTISTE de LAMARCK (1744-1829) proposed three theories about evolution 1. THEORY OF NEED -the production of a new organism or part of the organism arises from the need for it. 2. THEORY OF USE AND DISUSE - continued use of an organ strengthens it and continued disuse of an organ weakens it until it disappears 3. THEORY OF INHERITANCE OF ACQUIRED CHARACTERS -characteristics that have been acquired or changed during the lifetime of the organisms is transmitted to the offspring 191 DARWINISM (Charles Darwin 1809-1882) -proposed and formulated the process of EVOLUTION in his book “The Origin of Species” by means of natural selection. THEORY OF NATURAL SELECTION -According to Darwin, the chief factors responsible for the development of new species from common ancestry are as follows 1. OVERPRODUCTION – all organisms produce more offspring that can actually survive 2. STRUGGLE FOR EXISTENCE - because of overproduction, there is a constant struggle for existence among individuals 3. VARIATION AMONG INDIVIDUALS – plant breeders choose plants that are disease resistant or control the size or characteristics of fruits by experimentation (cross fertilization) 4. SURVIVAL OF THE FITTEST – slight variations in speed or instinct can mean survival for the fittest individual. In this way, nature selects the characteristics of a certain population by favoring even the slightest variation 5. TRANSMISSION OF THE VARIATION TO THE OFFSPRING – Darwin believed that these changes in the individual brought about by nature giving him a special fitness will automatically be transmitted to his offsprings as the type selected by nature to continue their species 192 RESULTS OF NATURAL SELECTION: Advance body organization and improve species Preserve and accumulate small-inherited modifications that are profitable for the species The favored form increases in number and generally the least favored decreases and become rare ORGANIC EVOLUTION defined as a change in genetics of a population over time (generations) a population refers to all individuals of the same species living in a defined area at the same time can be studied at two different levels 1. MICRO EVOLUTION -small scale genetic changes within populations -occurs through several mechanism 2. MACRO EVOLUTION -evolution within population -can also occur through several other mech. Ex. “speciation”- refers to the formation of new species; it occurs when one ancestral species evolves into more than one descendant species -brought about by variation, migration, environment change, selection and isolation 193 CONVERGENCE AND DIVERGENCE *CONVERGENT EVOLUTION / CONVERGENCE Two or more unrelated groups that adapt themselves to the same environment may show some common characteristics A condition nearly reverse to adaptive variation Ex. Fishes, whales and sea lions are all adapted to life in water *DIVERGENT EVOLUTION/DIVERGENCE Evolving of different characteristics in closely related groups An adaptive variation form of evolution Ex. A mammal like ancestor gave rise to bats, rabbits, elephant, whales 194 THE DIGESTIVE GLANDS Several Digestive glands aid in the breakdown of various organic substances in food. These are given in the table below indicating the enzyme they secrete and the action of each particular enzyme. REGION/GLANDS Mouth Salivary glands submaxillary sublingual parotid Pharynx Esophagus Stomach H cells chief cells DIGESTIVE ENZYME(S) salivary amylase (ptyalin) MODE OF ACTION Hydrolyzes starches to polysaccharides then to disaccharides maltose none none HCl mucin pepsin 195 lowers ph increases acidity of stomach lubricates the food splits proteins to proteases/pepto nes Small Intestine pancreas trypsin chymotrypsin carboxypeptides amylase breaks down polysaccharid es into a mixture of glucose & maltose breaks down fats to glycerol & fatty acids lipase liver/gall bladder mucosal lining Large intestine Cloaca/Anus (breakdown proteins & polypeptides to amino acids) bile emulsifier, enzyme) (an not bicarbonate enzyme) (not None none 196 facilitate digestion fats neutralizes acid of 197