Lifestyle Challenges in Post Pandemic Era Dr. Raka Islam Medical Officer Physical Medicine and Rehabilitation Dept. Shaheed Suhrawardy Medical College Hospital Introduction We are living in a planet of virus. Trillions of Bacteriophage working inside our body, making our living possible. Cont... Virus is our enemy too. Rhino virus first affected West Nile inhabitants. Endogenous retrovirus entered our genome 10 million years back. In 21st century, we encountered by SARS, MARS, Ebola and many more. Death toll is immense. Cont... • We are at the end of a pandemic COVID-19. • Till today death in world is 6.24 millions • In Bangladesh 29127 Cont... • Morbidity & Mortality due to COVID-19 found to be strongly related to comorbidities like DM, HTN, IHD, CKD, COPD • Most of which can be prevented or controlled by Lifestyle changes Cont… • Metabolic Syndrome is a major & escalating public health issue. • Urbanization, surplus energy intake, increase obesity and sedentary life style making it a challenge to mankind. • It confers 5 fold increase in risk of T2DM, 2 fold risk of CVD, 2 – 4 fold increase risk of Stroke and 2 – 4 fold increase risk of Myocardial infarction. Metabolic Syndrome The Metabolic Syndrome also known as Syndrome X, Insulin Resistance Syndrome, Dysmetabolic Syndrome - consists of a constellation of metabolic abnormalities that confer increased risk of cardiovascular disease and diabetes mellitus. Prevalence in India Age-standardized prevalence rates of MetS were 33.5% overall; Male 24.9%, Female 42.3%. Prevalence of Chronic Disease in US 6 in 10 Americans have a Chronic Disease 38% of Americans will be diagnosed with Cancer during their lifetimes Half of all Americans have CVD 1 in 3 have Pre-Diabetes, 90% do NOT know it 72% are Overweight or Obese Metabolic Syndrome Three of the following: • Waist Circumference : ≥90 cm (♂); ≥80 cm (♀) in South Asians • Fasting Triglyceride level : > 150 mg/dL • HDL Cholesterol level : < 40 mg/dL (♂); < 50 mg/dL (♀) • Blood Pressure : > 130 mm systolic or > 85 mm diastolic • Fasting Plasma Glucose level: ≥ 100 mg/dL * alternate: Previously diagnosed or on Medication Waist-Hip Ratio (WHR): Interpretation: High Risk WHR:> 0.80 for Females > 0.95 for Males Waist Indicates central (upper body) obesity and is considered high risk for diabetes & CVS disorders. Hip WHR = Waist/ Hip A WHR below these cut-off levels is considered low risk Hip Waist-Hip Ratio Standards for Men & Women Body Shapes :: Apple & Pear Carry more weight around Abdomen Carry more weight around Hip People having Metabolic Syndrome, typically have Apple-shaped bodies. Clinical Features Typically not associated with Symptoms. Elevated WHR & BP ?? CVD T2DM -NAFLD -HyperUricemia -Obstructive Sleep Apnea -Polycystic Ovary Syndrome** Risk Factors & Consequences Fatty Liver Disease Overweight/ Obesity Hypertension Sedentary Lifestyle Ageing Diabetes Mellitus Cardiovascular Disease Lipodystrophy Metabolic Syndrome Cancer Dementia Heart Disease Polycystic Ovary Laboratory Tests • Fasting lipids and glucose • apoB • hsCRP • Fibrinogen • Uric acid • Urinary albumin/creatinine ratio • Liver function • Testosterone • Luteinizing hormone • Follicle-stimulating hormone • A sleep study Management • The foundations of MetS management are essentially lifestyle modifications, like changes in dietary and exercise habits • Moreover, current evidence supports that diet and exercise, along with pharmacologic and surgical interventions, may inhibit the progression of MetS to T2D or CVD Lifestyle Modification Lifestyle Modification (contd..) Lifestyle Challenges • Obesity • Handling Stress • Work-Life balance • Spirituality • Diet • Lifelong commitment to a • Exercises • Restoration of Sleep Healthy Life-Style Obesity • Central obesity is the driving force behind the metabolic syndrome • Weight reduction is the primary approach • 5% to 10% weight reduction improves in Insulin Sensitivity and Metabolic Syndrome Recommendations for weight loss • A combination of • Caloric restriction • Increased physical activity and • Behavior modification Work life balance • Maximum 40 hours of work per week is healthy • In our country, We work > 40 hours/ week Diet Plan: Calorie Restriction ~ 500-kcal restriction daily = weight reduction of 1 lb. per week Carbohydrate restriction High-quality dietary pattern—(Fruits, Vegetables, Complex whole grains, Lean poultry, Fish etc) Many Diet Plans; should be individualized Intermittent Fasting Various meal timing schedules that cycle between voluntary fasting and non-fasting over a given period Good for Autophagy & Rejuvenation of Health Three methods: Time-restricted feeding Alternate-day fasting Periodic fasting Intermittent Fasting (contd.) Study shows that intermittent fasting may help with obesity, insulin resistance, dyslipidemia, hypertension, and inflammation and generally safe. Physical Activity • 60–90 min of daily activity is required to achieve modest weight reduction • Obese adult is unable to undertake this level of activity, a significant health benefit will follow from at least 30 min of moderate-intensity activity - daily Preparation for Exercises • Warm-up: consists of 5 – 10 min of aerobic activity • Activity session: 15 – 30 mins • Cool-down: similar to the warm-up and should last about 5 – 10 min Exercises The mnemonic ‘SAFE’ exercise are recommended: • Strengthening exercise • Aerobic exercise • Flexibility exercises • Endurance exercises Strengthening Exercise • Resistance training increases muscle strength by making them work against a weight or force • Includes using free weights, weight machines, resistance bands • Strength training improves the Insulin resistance and Metabolic syndrome Aerobic Exercise • With oxygen • Aerobic exercise is the type that moves large muscle groups and causes to breath more deeply and heart to work harder to pump blood. Its also called cardiovascular exercise. • It improves the health of heart and lungs Cardio-Pulmonary Rehab 6 Min Walk Test 10 Meter Walk Test Flexibility (Stretching) Exercise Flexibility exercises are aimed at increasing or maintaining range of motion at joints, also improve tone in muscles and keep it supple. They develop better muscular and body control. Endurance Exercise • Low resistance, exercises high repetition • Examples: Walking, Cycling, Swimming, or upper extremity ergometry that involve the use of the large muscle of the body Prescription of Exercise Exercises should be done according to FITT principle. Frequency Intensity Type Time : : : : 4 to 6 times/ week 30 to 40 min; 50-60% of target HR ‘SAFE’ exercises Morning is ideal time Restoration of Sleep Handling Stress Pharmacological Management • Dyslipidemia • HTN • Impaired Fasting Glucose • Insulin Resistance Surgical treatment • Bariatric Surgery (BS) and • Transcatheter Bariatric Embolotherapy Outline of Management Take Home Message - Prevention is better than Cure - Adoption of Healthy Lifestyle helps to prevent or manage Metabolic Syndrome, thus can reduce mortality & morbidity associated with Covid-19 - Exercises & Cardiopulmonary Rehab are essential components of LongCovid management - Self-Devotion & Commitment is a must to achieve the Goal Thank You