American University of Beirut Faculty of Arts and Sciences Department of Biology BIOL 223 (GENETICS- 4 credits) Prerequisite: BIOL 202 Instructor email Office AUB Extension Office hours General Lectures Recitations: Zakaria Kambris zk28@aub.edu.lb Biology 308 3911 M 10:00-11:00 am W 12:00- 1:00 pm or by appointment M+W F F F 9:00 - 9:50 am 9:00 - 9:50 am 10:00 - 10:50 am 11:00 - 11:50 am Colin Smith cs10@aub.edu.lb Biology 313 3887 WHF 4-5 pm CHEM 001 SLH PHYS 329 CHEM 001 Catalog Description BIOL 223 - Genetics Credits: 4.00, 3.3; 4 cr. Prerequisite: BIOL 202. Each semester. A course that deals with the basic principles of classical and modern genetics with emphasis on the analysis of genetic material and genetic processes at the molecular level. Course Learning Outcomes At the completion of this course, a student will be able to: 1- Understand and use common proper genetic notations (PLO 7); 2- Describe important historic experiments (PLO 7); 3- Explain mechanisms and regulation of replication and gene expression (PLO 4); 4- Analyze pedigree and inheritance and design breeding programs (PLO 5); 5- Describe the use of molecular genetics at the subcellular, cellular, organismal, and evolutionary levels (PLO 2); 6- Predict consequences of alterations to genetic material (PLO 3); 7- Construct and use genetic maps and complementation tests (PLO 3); 8- Work in the laboratory safely and efficiently (PLO 6); 9- Formulate and test hypotheses experimentally (PLO 5); 10- Properly record and present laboratory observations (PLO 1); 11- Perform common techniques such as gel electrophoresis, bacterial transformation, DNA extraction, RFLP analysis, and the polymerase chain reaction (PLO 6); 12- Design experimental approaches to basic and applied biological research questions (PLO 5); 13- Integrate information from many different areas of biology, chemistry, and physics (PLO 8); 14- Calculate probabilities in simple genetics systems (PLO 5); 15- Infer metabolic relationships from genetic data (PLO 5); 16- Debate ethical and social implications of genetics research (PLO 7); Resources Available to Students Required Textbook: Russell, P. J. 2010, iGenetics: A Molecular Approach, Pearson International Third Edition, The Benjamin/Cummings Publishing Company Some course material is available on AUB Moodle. Grading Criteria Kambris assessment Smith assessment Laboratory assessment 50% 25% 25% Exam I Exam II Final Academic Integrity: Please refer to AUB Student Code of Conduct http://www.aub.edu.lb/pnp/generaluniversitypolicies/Documents/StudentCodeConduct/StudentCodeC onduct.pdf and in particular section 1.1, which concerns academic misconduct including cheating, plagiarism, in-class disruption, and dishonesty. Please be aware that misconduct is vigorously prosecuted and that AUB has a zero tolerance policy. Topic Lecture Genetics: An Introduction DNA: The Genetic Material DNA: Replication Gene Function Gene Expression: Transcription Gene Expression: Translation DNA Mutation, DNA Repair, and Transposable Elements Exam I Sat 17 March (to be confirmed) Drosophila genetics - Development Recombinant DNA Cloning Technology Applications of Recombinant DNA Technology Genomics: Functional and Comparative Genomics Mapping and Sequencing of Genomes - Human Genome Project DNA Microarray Exam II Sat 28 April (to be confirmed) Mendelian Genetics & Chromosomal Basis of Inheritance Genetic Mapping in Eukaryotes Genetics of Bacteria and Bacteriophages Regulation of Gene Expression in Bacteria Regulation of Gene Expression in Eukaryotes Genetics of Cancer Final Exam To be announced Kambris Kambris Kambris Kambris Kambris Kambris Kambris Russell Chapters 1 2 3 4 5 6 7 Kambris Kambris Kambris Kambris Kambris Kambris 19 8 & 10 8 & 10 8&9 9 & 10 9 Smith Smith Smith Smith Smith Smith 11 & 12 14 15 17 18 20
