Uploaded by Huma Khan

Medical diseases and associated drugs/treatment

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Medical treatments:
Rickettsia: Doxycycline: 200mg/BD 5-7 days Chloramphenicol 500 mg 3 times a day 5-7 days
Medical abortion: Mifepristone (anti progesterone) 200 mcg and Misoprostol e1 analogue 800 mcg
(4tabs) 24-48hrs after mife pristoen 49-63 days after conception
Rabies: Essen regime 5 injections Zagreb 4 injection 0,3,7, 14, 28 or two on day 0 day 7 and day 21 antitoxin and diazepam
Tetanus: antitoxin, vaccine, diazepam
Arrhythmia in damaged cardiac tissue: IB (Mexilitine, tocainide, lidocaine)
Immediate anticoagulation: heparin
Type 2 DM: Dietary intervention, oral hypoglycemics, insulin
Ringworm: Terbinafine, griseofulvin and imidazole
Candiasis: systemic Amphotericin B and Oral Nystatin
Crytococcus Neoformans: fluconazole
Patent ductus arteriosus closure: indomethacine 0.2mg/kg/12hrs for 3 doses
Temporal Arteritis: High dose corticosteroids 40-60 mg/day 60-100mg/day
Schizophrenia negative symptons: Serotonin 2A antagonist 2nd generation anti-pyschotics
Aripiprazole, clonzapine, olanzapine, quetiapine, paliperidone, iloperidone, lurasidone, risperidone
ziprasidone
Alcohol abuse: Disulfiram and acamprosate
Diabetes Insipidus: central: desmopressin nephrogic: amiloride, hydrochlorothiazide and indomethacin
To keep PDA open: Alprostadil
Cytomegalovirus: Ganciclovir
Pnuemocystis jirovecii: TMP-SUX
Benign Prostatic hyperplasia: Finasteride, Tamsulosin
Buerger’s disease: smoking cessation
Carcinoid syndrome: octreotides
Malignant Hyperthermia: dantrolene
Chronic Gout: Overproducer: allopurinol Under excretory: probenecid
Acute gout: Nsaids and colchicine
Neisseria Meningitis: Pencillin/ceftriazone, Rifampin
Wegner’s Granulomatosis with polyangitis: cyclophosphamide and corticosteroids
ER positive breast cancer: Tamoxifen
Clostridium difficile: Metronidazole, Vancomycin
Mutiple sclerosis: b-interferon, immunosuppression, natazlizumab
Sickle cell Anemia: hydroxyurea
Depression: SSRI
Cytomegalovirus: Ganiclovir
Streptococcus Bovis: pencillin prophylaxsis
Bulimia: SSRI, Nystatin
Alcohol Withdrawal: benzodiazepine
Tonic Clonic: Phenytoin, valproate, carbamazepine
Gonorrhea: Ceftriaxone cover doxycycline-chlamydia
Generalized Anxiety Disorder: Buspirone
Prostate cancer/fibrosis: leuprolide/GnRH continuous
Malaria: chloroquine/mefloqine (blood schizont), primaquine (liver hypnozoite)
Hypercholesterolemia: statin
Hypertriglyceridemia: fibrate
Chlamydia Trachomatis: Doxycycline (+ceftriaxone) erythromycin in eyes
TB: RIPE rifampin, isoniazid, pyrazinamide, ethambutol
Enterococci: vanco.amp, aminoglycoside
Strep pneumonia: pen/cephalo, vanco(meningitis)
Acute Promyelocytic Anemia: All-trans retinoic acid
Infertility classic tm: leuprolide, pulsatile GnRH
Wafarin toxicity: acute-FFP chronic-vitamin K
Cystic Fibrosis: NAC, Anti-pseudomonas prophylaxis: Tobramycin/azithromycin
Hypertensive mom: Hpt Mom Love Nifeipine, hydralazine, methydopa, labetolol,
Nsaids in gastric ulcer: Celecoxib
Heparin induced thrombocytopenia HIT: Direct thrombin inhibitor = agatroban
Furosemide is a sulfa drug alternate: ethacrynic acid
Gynaecomastia causative: spironolactone switch on eplerenone, ketoconazole
Strep Pyogenes: Pencilin
CML: imatinib
Crohn’s: corticosteroids and infliximab
Stable angina: sublingual nitroglycerine
Hyperaldosteronism: spironolactone
Long term anticoagulation: warfarin
ED: sildenafil, verdanefil
Ulcerative colitis: 5-ASA, infliximab
SIADH: Demeclocycline, lithium and vasopressin receptor antagonist conivaptan, tolvaptan
Cyclophosphamide induced hemorrhagic cystitis Mesna
Antipsuedomonas antibiotics: Pip-tazo, cefepime, tobramycin, Cipro, tica-clav
Prolactinoma: dopamine agonist aka bromocriptine
Positive symptons of schiz: D2 receptor antagonist first and second generation anti pyschotics
Osteoporosis: Bisphosphonates, calcium and vit D
Trachomonas Vaginalis: Metronidazole
Migrane: Sumatriptan
Heparin : protamine sulphate
DKA: fluids, insulin and K
Hib: Rifampin
Bipolar: Lithium, valproate, Carbamazepine, lamotrigine
Prostate cancer: flutamide
Pulmonary Arterial Hypertension: Sildenafil, bosentan, epoprostenol
Her2/neu positive breast cancer: trastuzumab
Chronic Hepatitis: IFN alpha
Pheochormocytoma: a-antagonist phenoxybenzamine
Treponema pallidum: pencillin
Breats cancer on post menopausal women: anastrazole
Sporothrix Schenckii: oral potassium iodide
Toxoplasmosis Gondi: Sulfadiazine, pyrimethamine
Osteomalacia/rickets: vitamin D
Ethylene. methonal intoxication: fomepizole
Prolactinoma: Bromocriptine (dopamine agonists)
Osteoporosis: Bisphosphonates, vitamin D, calcium
Trichomonas Vaginalis: metronidazole
Neural tube defect: folic acid
Migrane: sumatriptan
Absence: Ethosuximide
Heparin: Protamine sulphate
DKA: K+, insulin, fluids
Haemophilus influenza B: rifampin
Bipolar: lithium, lamotrigine, valproate, carbamazepine
Prostate cancer: flutanide
Pulmonary arterial hypertension: sildenafil, bosentan, epoprostol
Chronic hpt: IFN-a
Pheochromocytoma: a-antagonists phenoxybenzamine
MRSA: vancomycin
Treponema Pallidum: pencillin
Breast ca in postmenopausal women: aromatase inhibitor anastrozole
Sporothrix schenckii: oral k iodide
Toxoplasma gondii: sulphadiazine pyrimerhamine
Osteomalacia/rickets: vit D
Ethylene/methanol: fomepizole
Anticoagulation: heparin
Hyperaldosteronism: Spironolactone
Wegener’s granulomatosis with polyangitis: cyclophosphamide, corticosteroid
Arrhythmia in cardiac: lidocaine, mexiletine, tocanide
Influenza: rimantidine, oseltamivir
Long term anticoagulation: Warfarin
Sickle cell anemia: Hydroxyurea
Malignant hypertension: dantrolene
Cml: imatinib
Clostrium tetani: antitoxin, vaccine, diazepam
UTI prophylaxsis: TMP-SUX
Bulimia: SSRI
Staph aureus: nafcillin, oxacillin, dicloxacillin mrsa: vanco
SiADH: lithium, demeclocycline, vasopressin receptor antagonist
Enterococci: vanco/ampi,
Cyclophosphamide induced- hemorrhagic cystitis: mesna
Tonic clonic: phenytoin, valproate, carbamazepine
ER positive breast ca” tamoxifen
ADHD: methylphenidate, amphetamines
Legionella: erythromycin
CLASSIC PRESENTATIONS:
ANTI-TOPOISOMERASE: DIFFUSE SCLERODERMA
Jaundice and non tender palpable gall bladder: distal
Enlarged cells with intranuclear inclusions: owl eye cells in cml
Renal epithelial casts in urine: acute toxic/viral nephrosis
Butterfly rash raynauds in a girl: SLE
Bacitracin sensitive: strep pyogenes
Bacitracin resistant: strep agalactaie
Rash on hands and feet: coxsackie A, secondary syphilis, rocky mountain spotted, Kawasaki
Lucid interval after head trauma: Epidural hematoma
Optochin sensitive: strep pneumonia Optochin resistant: viridans
Intranuclear eosinophilic droplet bodies: cowdry type A cmv hsv
Bloody LP: Subarachnoid haemorrhage if multiple if only one traumatic LP xanthochomic tap: previous
subarachnoid heam
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