Electrical Events During Neuronal Signaling (Stimulus è Graded Potential è Action Potential è Synaptic Transmission) GatedChannel (chemical, thermal, mechanical) © Kristie Lester 2014 Exercise #4: Question 1: Part (ii): 1. To the brain (sensory) – lateral spinothalamic pathway: Stimulus GP EPSP AP (temperature) First Order EPSP AP Second Order (PNS to spinal cord) AP POSTCENTRAL GYRUS Third Order (in spinal cord) (in brain) 2. From the brain: a) Corticospinal tract (somatic nervous system) GP EPSP/IPSP AP Upper Motor Neuron (in cerebral cortex) AP Lower Motor Neuron SKELETAL MUSCLE (in PNS – spinal or cranial nerve) b) Sympathetic (autonomic nervous system) GP EPSP AP Preganglionic (spinal cord to PNS) © Kristie Lester 2012 ACh* AP Postganglionic SWEAT GLANDS (in PNS) *usually sympathetic postganglionic neurons secrete norepinephrine as the nt (Fig. 14.2)