A Journal Reaction Paper on “Challenges in Lower-Limb Orthotic Research” A device affixed or applied to the exterior surface of the body to improve function, restrict or enforce motion, or support a body segment is referred to as an orthosis. Lower limb orthotics are specialized embedded systems which are used to rectify an incorrect alignment in specific parts of the lower limb. Braces, insoles, splints, and other devices are examples. Every lower limb orthotic is custom-made to match the demands of the wearer, and a podiatrist's full assessment and motion analysis are required. In the journal entitled “Challenges in Lower-Limb Orthotic Research”, I, as a reader, was no longer surprised upon knowing that even the most useful thing can still have its imperfection and challenge along the run. The lower-limb device has received complains that it is somehow not effective in correcting alignments of specific parts in the body. However, the articles in this special issue have relatively low levels of evidence supporting lower limb orthoses, based on study designs. The study by Bowers and Ross is maybe the exception in this problem, as it is based on a systematic review and so may be deemed Level I evidence. While conducting randomized clinical trials (which are considered to provide the highest degree of evidence due to the research design's capacity to restrict the influence of potential biases) is not always practicable or practical, and it is not always necessary. Furthermore, as stated in the article, heterogeneity within the population of orthosis users and within orthosis designs themselves is also a challenge to orthotic research. When designing a study, researchers must determine to what extent they will standardize the orthotic intervention being studied. This could lead to tighter inclusion criteria and difficulties with subject recruitment. Thus, it has been supported that even the designers and creators itself have admitted that the device may probably has its own challenges. Therefore, I agree that there is no such perfect study. Just as every research is, it undergoes trial and error, and as time goes by, improvements and developments were employed in order to have a better version of it; which then were made to help the people in every society.