Effect of Modafinil on blood pressure Modafinil is a great solution for achieving numerous health benefits. It is recommended by physicians for numerous reasons. One being its high potency of action. The action of Modafinil is by acting on the hypothalamus region of the brain. It helps in the secretion of hormones that helps achieve better brain activity with several other health benefits. One of the most common concerns associated with the use of Modafinil is its effect on the blood pressure. The Blood pressure is the pressure exerted by the blood on the blood vessel and artery of the person. The use of Modafinil dosage is not recommended for people with cardiac disorder. It is seen that the use of the Nootropic in heart patients can increase the heart beat and also cause elevation in the blood pressure of the person. People taking Modafinil should frequently get their bp and heart rate checked. It is safer for healthy people with no heart disorder.