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pharm chapter 4-6

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Chapter 4
assessment: information gathering regarding the current status of a particular patient, including
evaluation of past history and physical examination; provides a baseline of information and clues
to effectiveness of therapy
evaluation: part of the nursing process; determining the effects of the interventions that were
instituted for the patient and leading to further assessment and intervention
implementation: actions undertaken to meet a patient’s needs, such as administration of drugs,
comfort measures, or patient teaching
nursing: the art of nurturing and administering to the sick, combined with the scientific
application of chemistry, anatomy, physiology, biology, nutrition, psychology, and pharmacology
to the particular clinical situation
nursing diagnosis: statement of an actual or potential problem, based on the assessment of a
particular clinical situation, which directs needed nursing interventions
nursing process: the problem-solving process used to provide efficient nursing care; it involves
gathering information, formulating a nursing diagnosis statement, prioritizing the diagnoses,
developing goals and desired outcomes for the patient, carrying out interventions, and evaluating
the process
planning: the process of prioritizing the information gathered in assessment and, using the
established nursing diagnoses, to develop goals and desired outcomes for the patient
Assessment (gathering information) is the first step of the nursing process.
EX: history ( chronic conditions, drug use, allergies,etc)
Assessment #2: physical examination ( weight, age, drug effects)
Planning (goal setting, minimizing adverse effects, understanding drug
regiment
A
nursing diagnosis is simply a statement of the patient’s status from a nursing perspective
Implementation involves nursing interventions aimed at achieving the
goals of outcomes determined in the planning phase.
1. Drug administration
2. Provision of comfort measures
3. patient/family education
Comfort measures:
Managing adverse effects
1. Environmental control (temp, light. etc)
2. Safety measures (avoiding driving and the sun, using side rails)
3. Physical comfort measures (skin care, laxatives, frequent meals
Placebo effect
Nurses attitude can be a critical part of drug therapy
Lifestyle Adjustment
Evaluation: changes in assessment, diagnosis, and intervention
Key elements in any drug education program
1.
2.
3.
4.
5.
6.
7.
8.
Name,dose, and action of drug
Timing of administration
Special storage and preparation instructions
Specific OTC drugs or alternative therapies to avoid
Special comfort measures
Safety measures
Specific points about drug toxicity
Specific warnings about drug discontinuation
Chapter 5 : dosage calculations
apothecary system: a very old system of measure that was specifically developed
for use by apothecaries or pharmacists; it uses the minim as the basic unit of liquid
measure and the grain as the basic unit of solid measure
Clark rule: a method of determining the correct drug dose for a child based on the
known adult dose (assumes that the adult dose is based on a 150-lb person); it states
conversion: finding the equivalent values between two systems of measure
Fried rule: a method of determining a pediatric drug dose for a child younger than 2
years of age, based on the child’s age and the usual adult dose (assumes that an adult
dose would be appropriate for a 12.5-year-old child); it states
metric system: the most widely used system of measure, based on the decimal system;
all units in the system are determined as multiples of 10
ratio and proportion: an equation in which a ratio containing two known equivalent
amounts is on one side and a ratio containing the amount desired to convert and its
unknown equivalent is on the other side
Young rule: a method for determining pediatric drug dose based on the child’s age and
the usual adult dose; it states
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1 Kg = 1,000 g
1 Kg = 2.2 lbs.
1 L = 1,000 mL
1 g = 1,000 mg
1 mg = 1,000 mcg
1 gr = 60 mg
1 oz. = 30 g or 30 mL
1 tsp = 5 mL
1 lb. = 454 g
1 tbsp. = 15 mL
Measuring systems
- Metric system
- Apothecary system
- Household system
- Avoirdupois system
- Other systems
Metric system
Solid measure=
Gram (g)
1 milligram (mg)= 0.001 g
1 microgram (mcg)= 0.000001
1 kilogram (kg)= 1,000g
Liquid Measure=
Liter (L)
1 milililiter (mL) = 0.001L
1 mL= 1 cubic centimeter= 1cc
Apothecary
Solid measure=
Grain (gr)
60 gr= 1 dram (dr)
8 dr= 1 ounce (oz)
Liquid measure=
Minim (min)
60 min= 1 fluidram (fl dr)
8 fl dr= 1 fluid ounce (fl oz)
Household
Solid
Pound (lb)
1 lb= 16 ounces (oz)
Liquid measure:
Pint (pt)
2 pt= 1 quart (qt)
4qt= 1 gallon (gal)
16oz= 1 pt= 2 cups (c)
32 tablespoons (tbsp)= 1 pt
3 teaspoons (tbsp) = 1 tbsp
60 drp[s (gtt)= 1 tsp
The avoirdupois system is a system of measurement that use ounces and grains (
older system)
Calculating dose: oral drugs
Calculating dose: parenteral drugs
Calculating Dose: Intravenous Solutions
Pediatric dosage calculation
- Fried rule
- Young rule
- Clark rule
- Body surface area : most accurate
Fried rule
For children <2 years of age, this rule assumes that an adult dose would be
appropriate for a child who is 12.5 years (150 months) old
Young rule
Children 1-12 years of age
Clark rule
For infants under 1 year, uses child’s weight to calculate the appropriate dose
and assumes that the adult dose is based on a 150-lb person
Surface Area Calculation #1
Determine the child’s surface area with the use of a
nomogram (the height and weight of the child are
taken into consideration in this chart)
Chapter 6: Challenges to effective drug therapy
alternative therapy: includes herbs and other “natural” products as often found in
ancient records; these products are not controlled or tested by the U.S. Food and Drug
Administration and are considered to be dietary supplements; however, they are often
the basis for discovery of an active ingredient that is later developed into a regulated
medication
biological weapons: so-called germ warfare; the use of bacteria, viruses, and parasites
on a large scale to incapacitate or destroy a population
cost comparison: a comparison of the relative cost of the same drug provided by
different manufacturers to determine the costs to the consumer
internet: the worldwide digital information system accessed through computer systems
off-label uses: uses of a drug that are not part of the stated therapeutic indications for
which the drug was approved by the FDA; off-label uses may lead to new indications for
a drug
self-care: patients self-diagnosing and determining their own treatment needs
street drugs: nonprescription drugs with no known therapeutic use; used to enhance
mood or increase pleasure
Media influence
- 1990s: legal to advertise prescription drugs directly to the public
- Federal guidelines: When the advertisement states the indication, it must also
include:
- Contraindications
- Adverse effects
- Precautions
-Herbal medications of alternative therapies are not controlled or tested by the FDA.
Off-Label uses
Definition
The use of a drug for an indication not approved by the FDA
Occurrence
-Commonly done for groups of patients for which there is little premarketing
testing
-Used with pediatric and geriatric population
-May lead to discovery of new use for a drug
-Liability issues are fuzzy
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