Option A1. Neural development Essential idea: Modification of neurons starts in the earliest stages of embryogenesis and continues to the final years of life. A.1.U1 The neural tube of embryonic chordates is formed by in folding of ectoderm followed by elongation of the tube A.1.U2 Neurons are initially produced by differentiation in the neural tube A.1.U3 Immature neurons migrate to a final location A.1.U4 An axon grows from each immature neurons in response to chemical stimuli A.1.U5 Some axons extend beyond the neural tube to reach other parts of the body A.1.U6 A developing neuron forms multiple synapses A.1.U7 Synapses that are not used do not persist A.1.U8 Neural pruning involves the loss of unused neurons A.1.U9 The plasticity of the nervous system allows it to change with experience Applications A.1.A1 Incomplete closure of the embryonic neural tube can cause spina bifida A.1.A2 Events such as strokes may promote reorganization of brain function What conclusion regarding the effect of post-rehabilitation of stroke survivor can you make using the fMRI images below? Place your mouse pointer on the images to view the conclusion Skills A.1.S1 Annotation of a diagram of embryonic tissues in Xenopus, used as an animal model, during neurulation Can you identify the Xenopus embryonic tissues in the electron micrograph below Place your mouse pointer on ECG to view tissue labels