ANXIETY DISORDERS •A common dimension of day-to-day human experiences •An unpleasant emotion characterized by a feeling of vague, unspecified harm. ANXIETY DISORDERS • Marked by experience of physiological arousal, apprehension or feeling of dread, hyper vigilance, avoidance and sometimes, a specific fear or phobia FEAR VS ANXIETY FEAR - immediate alarm reaction to danger - Response to a known, external, definite or non-conflictual threat - Response to an immediate threat ANXIETY - Negative mood state characterized by bodily symptoms of physical tension and by apprehension about the future - Response to a threat that is unknown, internal vague or conflictual - Apprehension about a future threat ANXIETY DISORDERS • Primary determination of whether the fear or anxiety is excessive or out of proportion is made by the clinician, taking cultural contextual factors into account. • Can develop in childhood and persist into adulthood if not treated • Most occur in females than males (2:1) CAUSE OF ANXIETY DISORDERS • Biological Contributions - We inherit a tendency to be tense, uptight, and anxious - Behavioral Inhibition System (BIS): - Tendency is to freeze - Activated by signals from the brain stem of unexpected events that might signal danger. - Fight/Flight system (FFS): - Immediate alarm-and-escape response like panic. Environment can change the sensitivity of these brain circuits. - Ex: teenage smoking can lead to early GAD or panic disorder CAUSE OF ANXIETY DISORDERS Psychological Contributions • Freud: anxiety was a psychic reaction to danger surrounding the reactivation of an infantile fearful situation • “Sense of uncontrollability” / locus of control: higher, more anxious • Parents’ actions in childhood: Parents’ positive and predictable responses: less anxious. Negative/ overprotective: more anxious Social Contributions • Marriage, divorce, difficulties at work, death of a loved one, pressures to excel in school Triple Vulnerability Theory COMORBIDITIES Comorbidity: Co-occurrence of two or more disorders in an individual • Anxiety disorders with depression/ major depression • Diagnoses of depression or alcohol or drug abuse makes it less likely to recover from anxiety disorder and more likely to relapse Physical Comorbidities: • Anxiety disorder with thyroid disease, respiratory disease, gastrointestinal disease, arthritis, migraine headaches • Panic disorders and cardio, respiratory, gastrointestinal, and vestibular (inner ear) disorders SUICIDE - Weissman study: 20% of patients with panic disorder had attempted suicide - Anxiety or related disorder increases the chances of having thoughts about suicide (suicidal ideation) or making suicidal attempts - Strongest with panic disorder and posttraumatic stress disorder CLASSIFICATIONS OF ANXIETY DISORDERS • SEPARATION ANXIETY DISORDER • SELECTIVE MUTISM • SPECIFIC PHOBIA • SOCIAL ANXIETY DISORDERS • PANIC DISORDER • AGORAPHOBIA • GENERALIZED ANXIETY DISORDERS • SUBSTANCE/MEDICATION INDUCED ANXIETY DISORDERS SEPARATION ANXIETY DISORDER A. Inappropriate and excessive fear or anxiety concerning separation from those to whom the individual is attached (3 or more) 1. Excessive distress when anticipating or experiencing separation from home or from major attachment figures. SEPARATION ANXIETY… 2. Worry about losing major attachment figures 3. Worry about experiencing an untoward event from a major attachment figure. 4. Reluctance or refusal to go out because of fear of separation 5. Excessive fear or reluctance about being alone without attachment figures at home or in other settings SEPARATION ANXIETY… 6. Reluctance or refusal to sleep away from home or to go to sleep without being near a major attachment figure. 7. Repeated nightmares involving the theme of separation. 8. Repeated complaints of physical symptoms when separation from major attachment figures occurs or is anticipated. SEPARATION ANXIETY b. Fear, anxiety, or avoidance is persistent lasting for 4 weeks for children and 6 months or more for adults c. Disturbance causes distress d. Disturbance is not caused by another disorder RISKS FACTORS •Develops after life stresses, especially loss (ex. death of a relative or a pet) •Parental overprotection and intrusiveness SELECTIVE MUTISM a. Consistent failure to speak in specific social situations in which there is an expectation for speaking (e.g., at school) despite speaking in other situations. b. Disturbance interferes with educational or occupational achievement or with social communication. SELECTIVE MUTISM c. Duration of the disturbance is at least 1 month (not limited to the first month of school). d. the failure to speak is not attributable to a lack of knowledge of, or comfort with, the spoken language required in the social situation. e. the disturbance is not better explained by a communication disorder ASSOCIATED FEATURES • Excessive shyness • Fear of embarrassment • Social isolation and withdrawal • Clinging • Temper tantrums SPECIFIC PHOBIA A. Marked fear or anxiety about a specific object or situation B. Exposure to the stimulus provokes an immediate anxiety c. Phobic object or situation is actively avoided or endured with intense fear or anxiety. CONT… d. the fear or anxiety is out of proportion to the actual danger e. fear or anxiety or avoidance is persistent lasting for 6 months f. fear or anxiety or avoidance causes distress g. the anxiety is not better explained by another mental disorder SPECIFIC PHOBIA •Animal type •Natural environment type •Blood-injection-injury type •Situational type •Other types (loud sounds) Table 5.2 Words Used to Describe Highly Unlikely Phobias Fear Phobia Anything new Neophobia Asymmetrical things Asymmetriphobia Books Bibliophobia Children Pedophobia Dancing Chorophobia Englishness Anglophobia Garlic Alliumphobia Peanut butter sticking to the roof of the mouth Arachibutyrophobia Technology Technophobia Mice Musophobia Pseudoscientific terms Hellenophobia Table 5.3 Types of Specific Phobias Type of Phobia Source of Fear Associated Characteristics Animal Animals (e.g., snakes, insects) Generally begins during childhood Natural environment Aspects of the natural environment (e.g., Generally begins storms, heights, water) during childhood Blood, injection, Blood, injury, injections, or other invasive Clearly runs in families injury medical procedures Situational Specific situations (e.g., public Tends to begin either transportation, tunnels, bridges, elevators, in childhood or in mid- flying, driving, closed spaces) 20s. Fear of choking, fear of contracting an — Other illness, etc.; children’s fears of loud sounds, clowns, etc. DEVELOPMENT It can sometime develop: • After a traumatic event •Observation of others going through a traumatic event •An unexpected panic attack in the feared situation •informal transmission However, many are unable to recall the cause ETIOLOGY OF SPECIFIC PHOBIAS • CONDITIONING • MOWRER’S TWO-FACTOR MODEL • PAIRING OF STIMULUS WITH AVERSIVE UCS LEADS TO FEAR (CLASSICAL CONDITIONING) • AVOIDANCE MAINTAINED THOUGH NEGATIVE REINFORCEMENT (OPERANT CONDITIONING) Copyright 2009 John Wiley & Sons, NY 29 SOCIAL ANXIETY DISORDER (SOCIAL PHOBIA) • Starts in mid-teens • Duration is life long • Frequently appears among first degree biological relatives CRITERIA FOR SOCIAL ANXIETY DISORDER (SOCIAL PHOBIA) A. Marked fear or anxiety about one or more social situations in which the individual is exposed to possible scrutiny by others. Exposure to the feared social situation provokes anxiety B. The individual fears that he or she will act in a way or show anxiety symptoms that will be negatively evaluated CRITERIA FOR SOCIAL PHOBIA c. Social situations almost always provoke fear or anxiety. d. The social situations are avoided or endured with intense fear or anxiety. e. Fear or anxiety is out of proportion to the actual threat posed by the social situation and to the sociocultural context. CRITERIA FOR SOCIAL PHOBIA f. Persistent and lasting for 6 months or more. g. the fear, causes clinically significant distress or impairment in important areas of functioning. h. Not caused by physiological effects of a substance i. the fear, anxiety, or avoidance is not better explained by the symptoms of another mental disorder j. if another medical condition (e.g., parkinson’s disease, obesity, disfigurement from bums or injury) is present, the fear, anxiety, or avoidance is clearly unrelated or is excessive. SPECIFIERS: • Performance only: they have performance fears that impairs in their professional lives they do not fear or avoid non-performance situations. ASSOCIATED FEATURES • Paruresis “shy bladder syndrome” • May be inadequately assertive or excessively submissive • May overly show rigid body posture • May be shy or withdrawn • Seek employment that does not require social contract • Men may be delayed in marrying whereas women prefer to be homemakers ETIOLOGY OF SOCIAL PHOBIA • AVOIDANCE OR SAFETY BEHAVIORS • AVOID EYE CONTACT, APPEAR ALOOF, STAND APART FROM OTHERS IN SOCIAL SETTINGS • COGNITIVE FACTORS • NEGATIVE SELF EVALUATION • HARSH, PUNITIVE SELF-JUDGMENT • FEAR OF NEGATIVE EVALUATION BY OTHERS • EXPECT OTHERS TO DISLIKE THEM • EXCESSIVE ATTENTION TO INTERNAL CUES • E.G., HEART RATE 37 PSYCHOLOGICAL TREATMENT OF PTSD • EXPOSURE TO MEMORIES AND REMINDERS OF THE ORIGINAL TRAUMA • EITHER DIRECT (IN VIVO) OR IMAGINAL • TREATMENT MAY INITIALLY INCREASE SYMPTOMS • MORE EFFECTIVE THAN MEDICATION OR SUPPORTIVE THERAPY • COGNITIVE THERAPY • ENHANCE BELIEFS ABOUT COPING ABILITIES • ADDING CT TO EXPOSURE DOES NOT IMPROVE TREATMENT RESPONSE • TREATMENT OF ASD MAY PREVENT PTSD • SHOWS BENEFITS EVEN 5 YEARS AFTER THE TRAUMATIC EVENT Spectrum Model of Social Phobia and Avoidant Personality Disorder PANIC ATTACK • An abrupt surge of intense fear or intense discomfort that reaches a peak within minutes • A panic attack is not a mental disorder • Can occur in the context of any anxiety disorder as well as other mental disorders • When the presence of a panic attack is identified, it should be noted as a specifier (ex. “ptsd with panic attacks”). Uncued / Unexpected attacks - Occur unexpectedly without warning - Panic disorder diagnosis requires recurrent uncued attacks. - Panic Disorders Cued / Expected attacks - Triggered by specific situations (e.g., tunnel, mountain climbing=heights) - More likely a phobia PANIC DISORDER • Higher risk on women; 2:1 ratio • Commonly develops in young adults; • 20 – 24 years old • 25% unemployed for more than 5 years because of symptoms • Prognosis worse when agoraphobia is present PSYCHOSOCIAL FACTORS • Cognitive-behavioral theories – classical conditioning • Psychoanalytic theories – arise from an unsuccessful defense against anxietyprovoking impulses. PANIC DISORDER • Recurrent unexpected panic attacks. • (4 or more) Physical Symptoms • Palpitations, pounding heart or accelerated heart rate • Sweating • Trembling or shaking • Sensations of shortness of breath or smothering PANIC DISORDER •Feeling of choking •Chest pain •Nausea or abdominal distress •Feeling dizzy, fainting, lightheaded or faint PANIC DISORDER • Chills or heat sensations • Paresthesias (numbness or tingling sensations) • Derealization or depersonalization • Fear of losing control or going crazy • Fear of dying PANIC DISORDER • at least one of the attacks has been followed by 1 month (or more) of one or both of the following: 1. Persistent concern or worry about additional attacks or the consequences 2. Significant change in behavior related to the attacks c. Not caused by a substance d. Not caused by a gmc RISK FACTORS OF PANIC DISORDERS • • • • • • • • • negative affectivity anxiety sensitivity history of fearful spells separation anxiety (not a consistent factor) childhood sexual and physical abuse smoking identifiable stressors before the panic attack offspring of parents with anxiety disorder respiratory disturbance (asthma) ETIOLOGY OF PANIC • INTEROCEPTIVE CONDITIONING • CLASSICAL CONDITIONING OF PANIC IN RESPONSE TO BODILY SENSATIONS • PEOPLE WITH PANIC DISORDER SUSTAIN CLASSICALLY CONDITIONED FEARS LONGER ETIOLOGY OF PANIC • COGNITIVE FACTORS • LACK OF PERCEIVED CONTROL CAN TRIGGER PANIC • FEAR OF BODILY CHANGES • INTERPRETED AS IMPENDING DOOM • I MUST BE HAVING A HEART ATTACK! • BELIEFS INCREASE ANXIETY AND AROUSAL • CREATES VICIOUS CYCLE 57 TABLE 5.7 SAMPLE ITEMS FROM ANXIETY SENSITIVITY INDEX Table 5.7 Sample Items from the Anxiety Sensitivity Index Unusual body sensations scare me. When I notice that my heart is beating rapidly, I worry that I might have a heart attack. It scares me when I feel faint. It scares me when I feel “shaky” (trembling). Source: Peterson & Reiss, 1987. Note: People respond to each item on a 0 (very little) to 4 (very much) scale. AGORAPHOBIA a. Fear or anxiety in two or more of the following: 1. Public transportation 2. Open spaces. 3. Enclosed places 4. Standing in line or being in a crowd. 5. Being outside of the home alone. AGORAPHOBIA… b. Fears/ anxiety are due to thoughts that escape might be difficult c. Provoke anxiety d. Avoided or endured with anxiety e. Fear/anxiety is out of proportion f. Fear/anxiety is persistent lasting 6 months g. Fear/anxiety causes distress h. If a medical condition is present, the fear/ anxiety is in excess i. Fear/anxiety is not caused by another disorder ETIOLOGY OF AGORAPHOBIA • FEAR-OF-FEAR HYPOTHESIS (GOLDSTEIN & CHAMBLESS, 1978) • EXPECTATIONS ABOUT THE CATASTROPHIC CONSEQUENCES OF HAVING A PUBLIC PANIC ATTACK. • WHAT WILL PEOPLE THINK OF ME?!?! Copyright 2009 John Wiley & Sons, NY 61 GENERALIZED ANXIETY DISORDER A. Excessive anxiety and worry occurring more days than not for 6 months in a number of events or activities B. Controlling the worry is difficult GENERALIZED ANXIETY DISORDER c. 3 or more of the following (one for children) 1. Restlessness or feeling keyed up or on edge. 2. Easily fatigued. 3. Difficulty concentrating or mind going blank. 4. Irritability. 5. Muscle tension. 6. Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep). GENERALIZED ANXIETY DISORDER • Females are twice as likely as males to experience gad • 1/3 of the risk of GAD is genetic • Common worries: - Relationships, health, finances, daily hassles • Often begins in adolescence or earlier GENDER & SOCIOCULTURAL FACTORS • WOMEN ARE 2X AS LIKELY AS MEN TO HAVE ANXIETY DISORDER EXCEPT FOR OCD • POSSIBLE EXPLANATIONS • WOMEN MAY BE MORE LIKELY TO REPORT SYMPTOMS • WOMEN MORE LIKELY TO EXPERIENCE CHILDHOOD SEXUAL ABUSE • WOMEN SHOW MORE BIOLOGICAL STRESS REACTIVITY • SOCIOCULTURAL FACTORS • FOCUS OF ANXIETY VARIES • TAIJIN KYOFUSHO • JAPANESE FEAR OF OFFENDING OR EMBARRASSING OTHERS • RATIO OF SOMATIC TO PSYCHOLOGICAL SYMPTOMS APPEARS SIMILAR ACROSS CULTURES RISK FACTORS: PERSONALITY • Behavioral inhibition • Tendency to be agitated, distressed, and cry in unfamiliar or novel settings • observed in infants as young as 4 months • may be inherited • Predicts anxiety in childhood and social anxiety in adolescence • Neuroticism • React with negative affect • Linked to anxiety and depression RISK FACTORS: SOCIAL • NEGATIVE LIFE EVENTS • JOB LOSS, END OF RELATIONSHIP, ETC. • SEVERE STRESSORS OFTEN PRECEDE ONSET 80% WITH PANIC DISORDER • 70% WITH ANY ANXIETY DISORDER