Mutations A mutation involves a change in the order of the bases (A,T,C,G) in DNA. A mutation can happen while the mRNA is being made, or at any other time in the cell's life. Type of gene mutations: ● Addition: an additional base is ______________________ ● Deletion: one of the bases is _______________________ ● Substitution: one of the bases is ______________ with another. Consider the following sentence: Thedogatethecatandthemanwasmad Treat the sentence like mRNA - when broken down into “codons” you have: What if the following mutations occurred? ● Addition (Add a h after the first a) ○ ● Deletion (Remove the first e) ○ ● The dog hat eth eca tan dth ema nwa sma d Thd oga tet hec ata ndt hem anw asm ad Substitution: What if we change a letter? ○ The dog ate the cat and the tan was mad ○ The dog ate the hat and the man was mad ○ The log ate the cat and the man was mad Effects of mutations: Positive Mutation: Mutations that have a _____________________________ on the human. Negative Mutation: Mutations that have a _____________________________ on the human. Neutral Mutation: a mutation that has _______________________________________ effect.