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Magnetic nanoparticles drug delivery and bioimaging applications - ScienceDirect

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5/5/2021
Magnetic nanoparticles: drug delivery and bioimaging applications - ScienceDirect
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Metal Nanoparticles for Drug Delivery and Diagnostic
Applications
Micro and Nano Technologies
2020, Pages 189-213
Chapter 11 - Magnetic nanoparticles: drug delivery and
bioimaging applications
Salma Mirza 1, 2, Malik Shoaib Ahmad 3, Muhammad Ishaq Ali Shah 4, Muhammad Ateeq 4
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https://doi.org/10.1016/B978-0-12-816960-5.00011-2
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Abstract
The applications of nanotechnology in different fields of medical science have revolutionized the
healthcare sector for the diagnosis and treatment of several lethal diseases including cancer.
Magnetic nanoparticles (MNPs) are one of the most used nanomaterials in disease diagnosis,
targeted drug delivery, and biomedical imaging, such as magnetic resonance imaging (MRI). The
unparalleled magnetic properties of the MNPs assigned certain characteristic features such as
they can be used at the cellular and molecular level in a biological system and are also suitable
materials to be used in drug delivery and MRI. The MNPs are in the front line, providing an
attractive platform as alternative agents, as carriers in drug delivery and MRI. To better address
the specific biomedical needs, MNPs with higher magnetic moments, specific size and surfaces,
with enhanced functionalities, have great applications in the detection, diagnosis, targeted drug
delivery, and treatment of different diseases such as cardiovascular disease, different types of
malignant tumors, and neurological ailments. To date, various types of MNPs have been designed
and synthesized according to their applications in detection of diseases, targeted drug delivery to
various disease sites and different body parts, monitoring drug delivery, and also disease
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Magnetic nanoparticles: drug delivery and bioimaging applications - ScienceDirect
treatment. This chapter will provide an insight view of the design, synthesis, and applications of
MNPs in disease diagnosis, targeted drug delivery, and MRI.
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Keywords
Magnetic nanoparticles; iron oxide nanoparticles; superparamagnetic iron oxide
nanoparticles; ferromagnetic nanoparticles; antiferromagnetic nanoparticles; drug
delivery; magnetic resonance imaging; bioimaging
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