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It belongs to a class of medications known as PDE-5 inhibitors, which aid in the treatment of impotence by boosting blood flow to the male reproductive organ. The active element in this medicine, sildenafil citrate, aids in increasing blood flow to the male reproductive organ. As a result, you begin to have hard, longlasting erections, which are required for engaging in an awesome sexual activity. How Fildena looks? Fildena comes in triangle shape with purple colour and which known as a Fildena 100mg Purple Pill. What are phosphodiesterase inhibitors and How they work? In most cases, phosphodiesterase inhibitors operate by blocking phosphodiesterase enzymes. This also helps to prevent enzymes from breaking down the cAMP and cGMP molecules in the cell. A chemical called nitric oxide regulates the creation of cAMP and cGMP. The primary role of cAMP and cGMP is to help regulate physiological processes by lowering calcium levels in the cell. Phosphodiesterase enzymes break down both cAMP and cGMP in the end. Keep in mind that PDE-5 inhibitors are a type of medication that is used to treat erectile dysfunction in males. ED is the most frequent sexual disorder in males, and it is increasing in prevalence among men of all ages. Erectile dysfunction is caused by a lack of blood supply to the male reproductive organ, and PDE inhibitors are the initial therapy option for those who have it. When phosphodiesterase is inhibited, what occurs next? It becomes more difficult to break down cAMP and cGMP when phosphodiesterase is inhibited. As a result, their levels inside the cell rise, causing the cell’s calcium levels to drop. Finally, the targeted tissues experience vasodilation and smooth muscular relaxation. Is fildena is phosphodiesterase inhibitor? Yes, fildena 100mg are a PDE5 inhibitor that is used to effectively treat erectile dysfunction or impotence. 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