MUSCULOSKELETAL SYSTEM PHYSIOLOGY QUESTION 1 Which of the following ions stimulates neurotransmitter secretion in the neuromuscular junction? a. Sodium b. Potassium c. Calcium d. Magnesium ANSWER: C QUESTION 2 Which of the following is correct sequence for events happening at neuromuscular junction? A. Action potential in the motor neuron; depolarization of the muscle end plate; uptake of Ca2+ into the presynaptic nerve terminal B. Influx of Ca2+ into the presynaptic terminal; release of acetylcholine (ACh); depolarization of the muscle end plate C. Release of ACh; action potential in the motor neuron; action potential in the muscle D. Influx of Ca2+ into the motor end plate; action potential in the motor end plate; action potential in the muscle ANSWER: b QUESTION 3 An action potential in the motor end plate rapidly spreads to the central portions of the muscle cells by which of the following means? a) Z-lines b) sarcoplasmic reticulum c) pore in the plasma membrane d) transverse tubules answer: D QUESTION 4 Which of the following is the functions of tropomyosin in skeletal muscle? A. Sliding on actin to produce shortening B. Releasing Ca2 + after initiation of contraction C. Binding to myosin during contraction D. Acting by covering up the sites where myosin binds to actin ANSWER: D