KEY WORD DEFINITIONS Acid base balance: - the mechanisms the body uses to keep its fluid close to neutral; pH (normal level of 7.35 – 7.45), neither basic nor acidic, so the body can function normally. Lungs and Kidneys are integral in maintaining the normal acid base balance. Aldosterone: - a steroid hormone of the adrenal cortex that functions in the regulation of salt and water balance of the body. Angiotensin: - either of two forms of kinin of which one has vasoconstrictive action. OR a synthetic amide derivative of the physiologically active form used to treat some form of hypotension. Antidiuretic hormone (ADH): - also called vasopressin. A polypeptide hormone secreted by the posterior lobe of the pituitary gland or obtained synthetically that increases blood pressure and decreases urine flow. Diffusion: - the state of being spread out or transmitted especially by contact, the action of diffusing. Edema: -an abnormal infiltration and excess accumulation of serous fluid in connective tissue or in serous cavity (called dropsy) Extracellular: - situated or occurring outside the cell or cells of the body. Hypertonic: -exhibiting excessive tone or tension. OR Having a higher osmotic pressure than a surrounding medium or a fluid under comparison. Hypotonic: - having a deficient tone or tension. OR Having lower osmotic pressure than a surrounding medium or a fluid under comparison. Interstitial space: -fluid filled areas that surround the cells of a given tissue. Also known as third space. Intracellular: - within the cells. Isotonic: - of equal tension. OR Denoting a solution in which body cells can be bathed without net flow of water ac ross the semipermeable cell membrane; also, denoting a solution having the same tonicity as anothe r solution with which it is compared. Natriuretic peptides: Any peptide that stimulates the kidneys to excrete salt and water. Osmolarity: - normal is 270 to 300 mOsm/L. The concentration of a solution in terms of osmoles of solutes per liter of solution. pH: - the acidity or alkalinity of a solution, based on the amount of hydrogen ions available Renin: - enzyme produced by the kidney in conditions of abnormally low blood pressure. An enzyme that converts angiotensinogen to angiotensin I. Third space: - interstitial space