Depth Filtration Normal Semi Depth Depth Type of Filter Depth Filter : commonly used to remove high dirt contamination, such as for the first filtration process. • Pall’s Depth Filter provide a wide range of pore size that would be compatible for a broad spectrum of sample. The membrane of filter can be double or single layer, but for the better performances we suggested to used double layer. • The membrane is thicker than the “normal” filter. • Type of Depth Modules Sheets Typical Depth Sheet Filter Materials Cellulose fibres extremely fine three dimensional sieve large internal surface area (void volume of 70-85 %) Filter aid Diatomaceous earth permeable, fine matrix Perlite - bulky, flaky particles Microfine cellulose Synthetic polymer positive zeta potential wet strength Trial Filter Format Scale-Up Filter Format Double Layer SUPRAdisc HP Graded Sheets Combination Media Type Top sheet – bottom sheet Application PDK5 K 900 P - K100P Post Fermenter PDH4 K 700 P - KS 50 P Post Fermenter PDE2 K 100 P - EKM-P Post Centrifuge PDD1 KS 50 P – EKS-P Post Centrifuge / Post TFF Top sheet - Coarse grade Bottom sheet - Fine grade Drainage plate Bottom sheet - Fine grade Top sheet - Coarse grade