Running head: HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT Investigating Heart Math as a Treatment for Substance Abuse in an Inpatient Setting Edward McMillan Clinical Mental Health Counseling, Lenoir Rhyne University EDU 505 Research & Statistics Richard Trent Codd, III 10/27/2020 1 HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 2 Abstract The Heart Math system has existed and evolved over the last 25 years and has recently experienced a significant increase in scientific exploration. Heart Math claims its biofeedback tools and processes facilitate physical and emotional well-being through the trained increase in cardiac coherence. The process it teaches includes the practices of active gratitude and heartcentered breathing techniques. The scientific literature is noticeable lacking in the analysis of these practices and their individual associations with cardiac coherence and resulting increases in psychological and physiological well-being. This proposed 2x2 factorial analysis is intended to investigate the interactions and associations among several variables, including gratitude and heart-centered breathing practices, cardiac coherence, state and trait anxiety and craving in a sample of individuals who are clients of a 90 day substance use disorder inpatient treatment system. Keywords: Heart Math, Cardiac Coherence, Substance Abuse Treatment HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 3 Investigating Heart Math as a Treatment for Substance Abuse in an Inpatient Setting Heart Math is biofeedback system based on the heart rhythm coherence hypothesis (McCraty, et al. 2009). The hypothesis holds that the stability and pattern of heart rate activity from beat-to-beat (Heart Rate Variability) encode biological data over “macroscopic time scales,” which then effects cognitive performance and emotional experience. (McCraty, et al. 2009). The researchers at the Heart math institute further assert that this encoded information in heart rate variability can help synchronize the entire physiological system, which they term “Physiological Coherence” (McCraty & Childre, 2010). It is their thesis that heart-centered breath, gratitude and other positive emotions in general, as well as those emotions which are selfinduced, shift the heart and the system as a whole into this universally coherent and harmonious physiological state which is associated with improved performance, increased self-regulation, and overall sense of well-being (Shaffer et al., 2014). The Heart Math website boasts that the system “empowers” individuals in the selfregulation of their emotions and behaviors in order to decrease stress, increase resilience, and to realize their natural intuitive guidance in order to make self-effective choices. They further claim that the system facilitates the break through to superior levels of “personal balance, creativity, insight and health” (About Heart Math, 2020). The website also links a google scholar list of 466 citations in text stating that heart math technologies and techniques have been utilized in over 300 peer-reviewed or independent published studies (About Heart Math, 2020). However, the vast majority do not seem to be published in peer reviewed journals ion addition to the criteria for being related to the techniques and technology of Heart Math being very generous. Heart Math is claimed to have significantly reduced anxiety in nearly half of an 11,000+ sample of users and claims that it is beneficial in treating addiction (About Heart Math, 2020). HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 4 Additionally, substance abuse treatment facilities have begun to advertise the use of the system with clients (Sanctuary Program Highlights, 2020). This proposed study seeks to investigate the efficacy of the Heart Math system in increasing cardiac coherence and decreasing both trait and state anxiety as well as substance craving in a sample of individuals in an inpatient substance abuse treatment setting. Additional interests of the proposal are the associations between the primary techniques of the system and the above stated variables. Literature Review Heart rate variability refers to the intervals of time between contiguous heartbeats (Lehrer et al., 2020). An increasing amount of research has shown that structured variability in heart rate is likely a reliable indication of both physical and psychological general health (Lehrer et al., 2020). Heart rate variability biofeedback (HRVB), a technique used to increase heart rate variability, has gained increasing popularity among psychotherapists interested in utilizing psychophysiology in their practice (Lehrer et al., 2020). Research has shown that HRVB results in improvements in a variety of psychological and physiological conditions, such as depression, anxiety, asthma, pain, and hypertension (Lehrer et al., 2020). HRVB is also related to improvements in numerous types of human performance, including dance, music, athletics, agility and concentration (Lehrer et al., 2020). HRVB has recently been put forth as an useful psychotherapy component that focuses on neurovegetative components of psychological issues and is thought to improve treatment effectiveness (Caldwell and Steffen 2018; Lehrer 2018; Wheeler 2018). While there have been clinical and theoretical support and calls for more research into the usefulness of HRVB and Cardiac Coherence Biofeedback as supplemental treatments in front line substance abuse disorder programs, very little has been published to date (Eddie et al., 2016; HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 5 Leyro et al., 2019). The small amount of research that has been conducted has not included cardiac coherence or heart math. A 2015 study found that HRVB reduced both anxiety and cravings in a sample of 48 alcohol dependent individuals undergoing inpatient treatment (Penzlin et al.) Alayan et al. found that a HRVB practice of more than 12 minutes per day was related to a decrease in cravings over time in a sample of university students (2019). Research Methods Research Questions 1. Will active heart focused breathing increase cardiac coherence? 2. Will active gratitude practice increase cardiac coherence? 3. Will heart focused and gratitude have a combined positive effect on cardiac coherence? 4. Will heart focused, gratitude, and cardiac coherence be associated with decreased state and trait anxiety? 5. Will heart focused breathing, gratitude, and cardiac coherence be associated with decreased drug craving? Hypothesis This proposal hypothesizes that gratitude and resonant breathing will have individual and combined positive effects on cardiac coherence in individuals with substance abuse disorders who are in a 90 day inpatient treatment facility. Additionally, gratitude, resonant breathing and cardiac coherence will have individual negative associations with state anxiety as measured by the state anxiety portion of the Spielberger State-Trait-Anxiety Inventory (STAI-Y) (Spielberger et al., 1975), general anxiety as measured by the Penn St. Worry Questionnaire (Meyer et al., HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 6 1990) and drug cravings as measured by the Brief Substance Craving Scale (Somoza et al., 1995). Operational Definitions Heart Focused Breathing: Focusing attention on the heart or center of the chest while practicing a comfortable and controlled breathing at a rate of 4.5-6.5 breaths per minute (Schaffer, 2014). Gratitude Practice: Focusing and refocusing one’s attention on those things or experiences that an individual has significant personal appreciation for (Heckendorf, 2019). Cardiac Coherence: “A coherent heart rhythm is defined as a relatively harmonic (sinewave-like) signal with a very narrow, high-amplitude peak in the LF region of the HRV power spectrum with no major peaks in the VLF or HF regions. Coherence is assessed by identifying the maximum peak in the 0.04–0.26 Hz range of the HRV power spectrum, calculating the integral in a window 0.030 Hz wide, centered on the highest peak in that region, and then calculating the total power of the entire spectrum. The coherence ratio is formulated as: (Peak Power/[Total Power – Peak Power])” (McCraty, 2011). ` State Anxiety: Temporary and fluctuating experience of anxiety to a relatively immediate stressor, in this case the daily experience of early substance abuse recovery within an inpatient setting (Leal et al., 2017). Trait Anxiety: A relatively stable personality characteristic describing individual differences related to the propensity to experience state anxiety or worry (Leal et al., 2017). Drug Craving: The desire to acquire and use a particular drug or combination of drugs for the purposes of altering ones state of being (Sayette, 2000). HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 7 Participants and Sampling Participants for this proposed study will be obtained through a convenience sample in order to control for those extraneous variables related to therapeutic differences as much as possible and to facilitate data collection. This sampling decision is discussed in more detail in the limitations section of this proposal. Participants will be drawn from within a large substance abuse treatment system (“system”) located in the United States. The system consists of 16 inpatient substance abuse treatment facilities which provide a ninety day inpatient substance abuse treatment program. Treatment modalities across the system are uniform in both material and structure. Participants will be recruited during or shortly after the intake process at each individual system facility. Requirements for inclusion include: a diagnosis of Substance Use Disorder according to the Diagnostic and Statistical Manual for Mental Disorders, 5th edition (American Psychiatric Association, 2013), a client of the system, in his or her first week of the system’s 90 day treatment program, with no serious cardiac issues or illnesses (including but not limited to arrhythmias), not currently on any medication or supplement regimen that treats or that may cause symptoms of anxiety, not currently diagnosed with a Personality Disorder, with no recent history or currently experiencing any form of psychosis, no experience with or working knowledge of heart math or cardiac coherence, with no metabolic or hormonal disorders, with full release from system facilities medical staff. The prospective convenient sample will be largely compiled of white adults aged between 18 and 50, with a mean age of 34 according to the system’s average clientele. The system accepts both in and out of network insurance pay, as well as private cash pay. Therefore, the prospective sample will likely be well above average socioeconomic status. This is very comparable to the average population across private inpatient substance abuse treatment centers and should offer little threat to the external validity for the HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 8 target population. However, substance abuse affects individuals across all socio-economic and racial lines and any application of the proposed intervention to other subgroups within the substance abuse treatment domain warrants further investigation. Experimental Measures and Tools State-Trait Anxiety Inventory State Scale The State-Trait Anxiety Inventory (“STAI”) is a relatively short assessment designed to measure both state anxiety and trait anxiety. The STAI state scale is made up of a total of 20 statements that require respondents to label how they feel at a particular point in time (e.g., calm, tense) by rating such on a 4 point scale of intensity, which ranges from “not at all” to “very much so” (Spielberger, 1975; Spielberger 1983). The assessment has been shown to have internal consistency and reliability estimates that are generally satisfactory for a broad range of studies across a large variety of populations. (Barnes et al., 2002). Penn St. Worry Questionnaire The Penn State Worry Questionnaire for Adults (“PSWQ”) is the most frequently used measure to assess trait anxiety or pathological worry in adults (Meyer, Miller, Metzger, & Borcovec, 1990). The PSWQ is a 16-item self-report questionnaire, compiled from a factor analysis of 161 items believed to be related to worry. The PSWQ is proposed to measure a respondent’s disposition to worry. Additionally, it measures the intensity, frequency, and individual tendency for worry to be generalized (Meyer et al., 1990). Individuals are instructed to rate each item of the assessment on a 5-point Likert scale that ranges from 1 (“not at all typical of me”) to 5 (“very typical of me”). The first eleven items are positively scored in relation to pathological worry (e.g. “my worries overwhelm me”), whereas the final five items on the instrument require reverse scoring and show worry as not being an issue (e.g. “I never worry HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 9 about anything”). The scores from each item are added together to yield a total score that ranges from 16-80, with higher scores representing higher levels of pathological worry (Meyer et al., 1990). Brief Substance Craving Scale (2007 edition) The 2007 edition of the Brief Substance Craving Scale (“BSCS”) is an 8 item (4 items each for primary and secondary drug of choice), self-report instrument assesses craving for substances of abuse over a 24 hour period. A five point Likert scale is used to record Intensity and frequency of craving. The instrument was designed by the Craving Subcommittee of the NIDA Medications Development Research Units (MDRU) and is an expansion of the Cincinnati Craving Scale. Reliability data for this instrument has been collected at the Cincinnati MDRU. The BSCS takes approximately 5 minutes (Somoza et al., 1995). emWave Pro Desktop System Heart rate data will be recorded with the emWave pro Desktop system (“EWD”) (HeartMath, LLC, Boulder Creek California). EWD utilizes a pulse sensor that attaches to the ear and plugs into a PC or Mac USB port. The heart rate variability monitoring system collects pulse data, measures and then translates cardiac coherence data into user-friendly biofeedback information and graphics displayed on a computer screen. The biofeedback data displayed is utilized by the user to learn how to recognize when he or she is out of coherence and what thoughts or emotions may have precipitated or caused that loss of coherence. This data is then used as a prompt to reenter cardiac coherence through the use of active gratitude practice and heart centered breathing. HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 10 Design and Procedure The proposed design for this prospective experiment is a 2 x 2 factorial design. The study will be conducted over a 6 month period, while each individual experiment will last 10 weeks. The design will be implemented in the following manner so as to minimize threats to internal validity. Each of the system’s 16 facilities will be assigned as either a Gratitude Treatment, Breath Treatment, Combined Treatment, or Control Group utilizing a block randomization method. Each participating intervention center will be randomly assigned to one of the four treatment conditions in 4 different rounds. Each condition must be filled once in each round before the next round begins and randomization is reset. This will be done in order to keep sample sizes as equal as possible and to facilitate the standardization and streamlining of the training for those system therapists who will be administering the various intervention conditions. All groups will be administered the Penn St. Worry questionnaire pre-test, within 48 hours of intake and post-test during discharge. Individual therapists at the system facilities will receive training in how to coach active gratitude practice and/or heart centered breathing depending on what group there facility is assigned to. All individual therapists within the system will receive training on how to use and train clients to use the emWave Pro cardiac coherence biofeedback system. Individual participation in the study will commence at the beginning of the participant’s second full week as a client in the facility’s program and conclude 10 full weeks later. Gratitude Treatment Group Those qualifying participants at facilities that are assigned to the Gratitude Treatment group will undergo 10 minutes of coaching in active gratitude practice at the end of their daily 90 HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 11 minute individual therapy session during the first week of the study as a primer. At the end of the first week, participants will receive a 30 minute training in the use of the emWave Pro. Beginning the second week participants will begin using the biofeedback system for two 10 minute sessions at the end of daily individual therapy. During the session the participant will be instructed to engage in active gratitude practice. In between and after biofeedback sessions the therapist and participant will briefly discuss what the participant noticed regarding the cardiac coherence biofeedback as it relates to the participant’s gratitude practice, as well as their emotional and mental processes. The participant will be encouraged to utilize any insights gained during subsequent sessions. Breath Treatment Group Those qualifying participants at facilities that are assigned to the Breath Treatment group will undergo 10 minutes of coaching in heart focused breathing practice at the end of their daily 90 minute individual therapy session during the first week of the study as a primer. At the end of the first week, participants will receive a 30 minute training in the use of the emWave Pro. Beginning the second week participants will begin using the biofeedback system for two 10 minute sessions at the end of daily individual therapy. During the session the participant will be instructed to engage in heart focused breathing. In between and after biofeedback sessions the therapist and participant will briefly discuss what the participant noticed regarding the cardiac coherence biofeedback as it relates to the participant’s breathing and attention on breathing or lack there-of. The participant will be encouraged to utilize any insights gained during subsequent sessions. HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 12 Combined Treatment Group Those qualifying participants at facilities that are assigned to the Combined Treatment group will undergo 10 minutes of coaching in active gratitude practice and 10 minutes of coaching in heart focused breathing practice at the end of their daily 90 minute individual therapy session during the first week of the study as a primer. At the end of the first week, participants will receive a 30 minute training in the use of the emWave Pro. Beginning the second week participants will begin using the biofeedback system for two 10 minute sessions at the end of daily individual therapy. During the session the participant will be instructed to engage in both active gratitude practice and heart focused breathing. In between and after biofeedback sessions the therapist and participant will briefly discuss what the participant noticed regarding the cardiac coherence biofeedback as it relates to the participant’s active gratitude practice, the participant’s breathing, as well as the participant’s mental and emotional processes. The participant will be encouraged to utilize any insights gained during subsequent sessions. Control Treatment Group Those qualifying participants at facilities that are assigned to the Control Treatment group will undergo 10 minutes of psychoeducation in relapse prevention at the end of their daily 90 minute individual therapy session during the first week of the study. At the end of the first week, participants will receive a 30 minute training in the use of the emWave Pro. Beginning the second week participants will begin using the biofeedback system for two 10 minute sessions at the end of daily individual therapy. The participants in the control treatment group will be instructed to work on a relapse prevention plan during the biofeedback sessions. In between and after the biofeedback sessions participants in this group will be allowed to briefly stretch, walk HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 13 around or used the bathroom. They will also be allowed to ask the therapist questions regarding their relapse prevention plans during and after the sessions. For participants in all groups, the Brief Substance Craving Scale will be administered at the beginning and the end of the participant’s individual therapy session on Mondays, Wednesdays, and Fridays. The State Scale portion of the State-Trait Inventory will be administered at the beginning and end of the participant’s individual therapy sessions on Tuesdays and Thursdays. Limitations Due to the intimate nature of inpatient living and the goal oriented nature of the cardiac coherence biofeedback software used, treatment diffusion among participants was a primary concern of this proposal. While the block randomization utilized is intended to control for treatment diffusion and its threat to internal validity, it along with the convenience sampling result in a reduction in the randomization of participants to the different treatment groups and significantly threatens external validity. Additionally, although system programming is consistently uniform across system facilities, even slight individual differences among therapist orientation and delivery in group and individual sessions could threaten internal and external validity. Individual participant needs will likely drive individual sessions and threaten both internal and external validity. The high frequency and repetition of testing measures also poses a threat to validity. Withholding parts of the treatment, relapse prevention work, and/or the entire treatment from participants is a significant ethical concern. This is especially true due to the serious and deadly nature of substance abuse disorders. In order to lessen the ethical and therapeutic impact of missing intervention aspects, participants will be offered free virtual training and therapy HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 14 consisting of those modalities not included in their assigned treatment group intervention. This will be done by the system’s after care coordinators and after care therapist. Prospective participants will only be told that they may take part in a study related to heart math and cardiac coherence. Although participants will not be told of the specific intervention aspects during intake and the informed consent process in order to protect internal validity, they will be assured that any treatment aspect that they did not experience will be offered at no extra charge. They will then be fully debriefed, reminded of this option during the discharge process and arrangements will be made according to their wishes. HEART MATH AS A SUBSTANCE ABUSE INPATIENT TREATMENT 15 Reference List American Psychiatric Association (2013). Diagnostic and statistical manual of mental disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596 About Heart Math. (2020). Heart Math. https://www.heartmath.com/about/ Alayan, N., Eddie, D., Eller, L., Bates, M. E., & Carmody, D. P. (2019). Substance craving changes in university students receiving heart rate variability biofeedback: A longitudinal multilevel modeling approach. 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