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Baltimore Classification Worksheet

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Baltimore Classification
Please post this assignment to Canvas by Monday, Nov 9th at 1:59 pm
Remember: ________Template_____ Dependent _______Product_____ Polymerase
Below are four polymerases used by viruses to either replicate their genome and/or make mRNA for protein synthesis. Complete the table with
your group. For this activity, we are working with a virus in a eukaryotic animal cell.
If encoded by the host, what is the purpose in the host
Location of enzyme in host cell?
cell?
Polymerase
Encoded by Host or Virus
DNA Dependent RNA
Polymerase
Host
Transcribe DNA to mRNA
nucleus
DNA Dependent DNA
Polymerase
host
Replicate DNA
nucleus
RNA dependent RNA
polymerase
virus
Transcribe RNA to RNA
cytoplasm
RNA Dependent DNA
Polymerase
virus
Translate dsRNA to dsDNA
nucleus
Draw a eukaryotic animal cell. Draw and label all of the enzymes and molecules necessary for DNA replication, transcription, and translation in the eukaryotic
cell. Have each viral class invade the cell and make multiple virions. Use your drawings to complete the table below.
mRNA template
Where is mRNA
produced?
Polymerase used to
synthesize mRNA
Polymerase used to synthesize
genome
dsDNA genome
nucleus
DNA Dependent RNA
Polymerase
DNA Dependent DNA
Polymerase
dsRNA
(-) ssDNA
cytoplasm
RNA Dependent DNA
Polymerase
RNA dependent RNA
polymerase
IV
(+) ssRNA
(+) ssRNA
cytoplasm
RNA dependent RNA
polymerase
RNA dependent RNA
polymerase
V
(-)ssRNA
(-) ssRNA genome
cytoplasm
RNA dependent RNA
polymerase
RNA dependent RNA
polymerase
VI
ssRNA w/ reverse
transcriptase
Incorporated dsDNA
nucleus
DNA Dependent RNA
Polymerase
DNA Dependent RNA
Polymerase
Class
Genome
I
dsDNA
III
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