NUTRITION STUDY GUIDE – METABOLIC – THEORY EXAM #2 Discuss normal digestion, absorption, and metabolism I. Basic Nutrition Principles A. Ingestion: consumption of food B. Digestion: food broken down into tiny nutrients in the stomach 1. Mechanical: involve neuromuscular processes that moves food through GI tract 2. Absorption: movement of smaller elements though the digestive walls into blood stream C. Basic metabolism: biochemical reaction within the cell of the body - Anabolism: build up Glycogenolysis: catabolism of glycogen into - Catabolism: breakdown glucose, carbon dioxide, water Glycogenesis: anabolism of glucose into Gluconeogenesis: catabolism of amino glycogen acids and glycerol into glucose for energy Identify essential nutrients, explain the significance of each nutrient, and identify their dietary sources. I. Dietary Sources of Essential Nutrients A. Energy Nutrients – macro nutrients 1. Carbohydrates: - Contain: carbon, hydrogen, oxygen - Keep body from using proteins for energy, - 4kal/gram prevent ketosis, enhance memory and - Major supplier of energy, include: sugars, learning capabilities starches, fiber - 45% to 65% of daily caloric intake Simple carbohydrates Complex carbohydrate Broken down & absorbed quick, quick source of energy Monosaccharides: glucose, fructose, galactose Disaccharides: sucrose, maltose, lactose Starches – made up of many units of glucose Take longer to break down, provide longer periods of energy ***Dietary fiber: non-digestive part of plants Soluble fiber: combine with waste to assist in their removal Oat bran, beans, apples, carrots Insoluble fiber: bulk the diet Whole grains, skin and seed of fruits Benefits of fiber: -Promote cardiovascular health (lower cholesterol level) -Weight control -Improve glycemic control in diabetes -Improve regularity -Enhance immune function 2. Protein - Development – maintenance – repair body tissues, organs, cells - May provide energy if body doesn’t have enough fat or carbohydrates - 10%-35% of daily intake - Amino acid: must be consumed in food every day because body doesn’t make or store it Complete proteins: contain all essential amino acids (animal-based) Incomplete proteins: lack 1 or more essential amino acids (veggies, seeds, nuts, grains) ***Amino acids that cannot be used for synthesis are converted to fat - Healthy people rarely need protein supplements - 2/3 serving of protein-rich food = daily need - Nitrogen: growth, pregnancy, maintenance of muscle mass and vital organs, wound healing 3. Fats - Very concentrated *Trans fat: AVOID!!! (raise LDL, lower HDL, - Are type of lipid (similar to carbohydrate, longer shelf life) less oxygen, not dissolve in water) Cholesterol: - 20%-35% of daily intake - waxy fat-like, produced in liver/ part of - Functions: supply energy/ insulate body/ cell membrane and nerve tissues protect vital organs or tissues/ facilitate - body use this to form vit D and other nerve conduction/ transport molecules/ hormones Component of many hormones - Found ONLY in foods come from animals - Categories: triglycerides/ Phospholipids/ (butter, eggs, meats) Sterols - Not essential - Types: - Adult <200, Child 120-200, Infant: 70*Monounsaturated: BEST! (olive oil, 175, Newborn: 53-135 peanut oil, avocado, nuts, canola oil) - Forms: LDL (deposit cholesterol on the Polyunsaturated (fish oil, vegetable oil, wall of blood vessels); HDL (removes sunflower oil) cholesterol from cell and bring it back to Unsaturated: liquid at room temp liver and intestine to be recycled or *Saturated: NOT GOOD! (solid at room excreted temp, animal source, tropical oil butter) - Omega 3 & 6: Necessary for blood clotting, normal brain and nerve system functioning Prevent atherosclerosis & lower triglyceride Improve learning ability/ enhance immune function/ improve arthritis symptoms Lower cholesterol Reduce risk of heart disease B. Regulatory Nutrients – micro nutrients 1. Vitamins Important for metabolic and physiologic functions DON’T PRODUCE ENERGY Water soluble Vitamin B Facilitate energy production Act as coenzyme to form RBCs B1: necessary for production of HCl (for digestion) B2: maintain healthy skin, adaptation to light B3: IN COFFEE – critical in formation of fatty acid Pantothenic acid B5: Biotin B7: form purines (essential for DNA & RNA) B6: synthesis & catabolism of amino acid B12: RBC production, maintain myelin (protective sheath of the nerve), necessary to make DNA B9 Folic acid: synthesis of DNA, RBC formation, neural tube defect Vitamin C Most important vitamin Collagen synthesis Antioxidant ENHANCE ABSORPTION OF IRON Promote strong immune system Help with infection & night vision Bone & teeth development Deficiency: night blindness, immunity, impaired growth and development Liver, milk, egg yolk, dark leafy green veggie, orange/yellow veggie and fruits “sunshine vitamin” Bone and tissue development (Collaborate with calcium and phosphorus) Development of collagen Dairy products, eggs, fortified products, liver, fatty fish (salmon, mackerel) Essential for protein synthesis (promote blood clotting) Synthesized in body by bacteria in large intestine Liver needs vitamin K to produce a protein called PROTHROMBIN Deficiency: bruising/ bleeding Dark leafy veggies: broccoli, spinach, Brussel sprout, cabbage Antioxidant, protect cell from free radicals Promote healthy immune system Nuts, seeds, soybean, canola, corn, other vegetable oils Excreted in urine Easily destroyed by light, air, cooking Not stored in body, must be digested daily Fat soluble Soluble in fats and can be stored in body tissues and tend to remain Hypervitaminosis: too much vitamins stored in body Vitamin A Vitamin D Vitamin K Vitamin E 2. Minerals - Quickly used or lost in waste products must consume every day - No calories - Calcium: nerve conduction, muscle contraction, blood vessel expansion/ contraction, secretion of hormone - Phosphorus: bone development, muscle contraction, kidney function, nerve conduction, heartbeat regularity - Magnesium: work with calcium, structural support, BP and heartbeat regulation, nerve/muscle function - Zinc >< magnesium Sodium/ Potassium/ Chloride: Iron: vital part of hemoglobin Iodine: thyroid gland functioning 3. Water - Function: Control body temp Maintain acid-base balance Regulate fluid and electrolytes Transporting nutrients and waste - Dehydration: excessive sweating, diarrhea, vomiting. Dietary Recommendations Special Diets Clear liquid Pureed Thickened Diabetic Renal Short period of time Juice (no pulp)/ see-through At room temp Blended – No nuts/ seeds Avoid raw egg Pt has difficulty swallowing/ risk for aspiration Thin: like normal beverages Nectar: sip through a straw Honey: eat w/ spoon, no straw Spoon-thick: have shape, eat w/ spoon Control carb/ avoid high glycemic food Prefer high fiber Restrict potassium/ sodium/ protein/ phosphorus Prefer fresh fruit, veggies Limit: meats, processed food, peanut butter, cheese, nuts *Fluid restriction Zinc: immune function, wound healing, blood clotting, thyroid function, maintaining vision Symptoms: headache, loss of concentration. Men: 3.7L/day, Women: 2.7L/day - Water intoxication: excessive intake, failure to excrete - 60%-70%: adult, 54%: older adult, 77%: newborn, 97% embryo Full liquid Mechanical soft Gluten free Cardiac Vegan All items in clear liquid Juice (with or w/o pulp)/ milk Yogurt/ pudding/ cream soup Easy to chew food No wheat, barley, rye, oats Low cholesterol/sodium Minimize animal products/ processed foods No meat Need B12 supplements Discuss factors influencing nutrition Factors Affecting Ingestion A. Physiological impairments -Limited mobility of hands and arms -Poor tolerance of activity -Poor cognition -Poor physical state B. Lifespan considerations - Infants: critical period, need: vitD, - Adolescents: need additional calories/ fluoride, iron proteins/ minerals/ B-vitamins, iron - Toddlers/ preschoolers: deficiency in girls due to menstruation Long life habits are established - Young/ middle-aged adults: calories Growth spurts requirement lower/ steadily decline Food safety - Older adult: over/under nutrition C. Psycho-social considerations 1. Economics: food insecurity 2. Dietary preferences: meaning of food Identify developmental nutritional considerations and describe how nutrition influences growth and development throughout the life cycle Nutrition is always relevant It helps to maintain or increase wellness Dietary factors could be the cause of illness or could help restoring health Identify risk factors for and clinical signs of malnutrition -Condition with ability to ingest, digest, -Obesity absorb nutrients -Anorexia nervosa/ bulimia -Congenital anomalies -cancer/ radiotherapy -Surgical revisions of GI tract -Immobilization -Fed through IV only for > 1 week -Living alone -Pregnant pt -Alcohol/ substance abuse -Poor dietary habit *Clinical signs: Eyes: dark circle/bags under eyes/ poor night vision/ ruptured blood vessel in eyes/ nearsightedness/ pale lower eyelid Teeth and gum: bleeding gum/ crowed teeth Hair: hair loss, dry hair, dandruff Nails: spoon shape, white marks, pale nails, brittle nails, cuticle tears easy Muscle & joint: cramping, twitching, edema swelling, numbness/ tingling, clicking joints Mouth: cracks in corner, weak tooth enamel, painful tongue, loss of smell or taste Skin: bumps on back of arms, dry/rough skin, unusual nosebleed, easy bruising, dermatitis, stretch marks CNS: depression, dementia, nervousness, irritability, insomnia, dizziness Identify classifications and factors relating to nutritional alterations of more than body requirement and less than body requirement 1. More than body requirement a) Classifications 1) Overweight: BMI 25-29.9 2) Obese: BMI 30-39.9 3) Extreme obesity: BMI 40+ b) Epidemiology c) Etiology and pathophysiology Body weight beyond physical requirement Abnormal increase and accumulation of fat cells Adipocytes: increase in number (hyperplasia) and size (hypertrophy) d) Genetics e) Physiologic regulatory mechanisms Research in: eating behavior, energy metabolism, body fat metabolism Leptin: suppresses appetite, increase fat metabolism (satiety hormone) Ghrelin: regulate appetite (hunger hormone) f) Environmental factors Access to food Lack of physical exercise Low socioeconomic status g) Psychological factors Associations begins in childhood Sense of satiety can be altered Mindless eating Eating is social, associated with pleasure and fun h) Health risks associated with obesity Cardiovascular problems (high LDL, low HDL, high triglycerides) Diabetes (type 2) GI and liver problems Respiratory and sleep problems (sleep apnea, obesity hypoventilation) Musculoskeletal problems: osteoarthritis, inflammatory mediators, cartilage deterioration, hyperuricemia and gout Cancer: breast, endometrial, kidney, colorectal, pancreas, esophagus, gallbladder Psychological problems: stigmatization, low self-esteem, social isolation, depression 2. Less than body requirement a) Malnutrition Lack of nutrients, insufficient to meet body metabolic needs Contribute factors: starvation and physical illness (surgery, injury, hospitalization, undernutrition, GI disease) b) Malabsorption Impaired absorption of nutrients from GI tract c) Clinical manifestations Poor wound healing Develop pressure ulcers, infection, muscle strength, post-op complication, increased morbidity and mortality risks Diagnostic studies Swallowing and Gag reflex Lab tests/studies A. Albumin (slow) B. Pre-albumin (preferred) C. Total Protein D. CBC D. Total Protein E. Serum glucose F. UA Discuss enteral nutritional administration A. Gastrointestinal intubation 1. Short-term nutritional support a. Nasogastric (NG) tubes b. Nasointestional (NI) tubes 2. Long-term nutritional support a. Percutaneous endoscopic gastrostomy (PEG) tube b. Gastrostomy tubes B. Tube feeding safety Identify blood components and their functions A. Blood Cells 1. Erythrocytes (RBC) 2. Leukocytes (WBC) 3. Thrombocytes (Platelets) B. Plasma and Plasma Proteins Blood tests A. CBC B. RBC C. WBC D. Hemoglobin (Hgb) E. Hematocrit (Hct) F. Platelets (Plt) G. Differential (Diff) Nutritional Anemias Across the Life Span A. Overview B. Iron Deficiency Anemia 1. Pathophysiology 2. Clinical Manifestations 3. Assessment and Diagnostic Findings 4. Medical Management 5. Nursing Management C. Folic Acid Deficiency Anemia 1. Pathophysiology 2. Clinical Manifestations 3. Assessment and Diagnostic Findings 4. Medical Management 5. Nursing Management D. Vitamin B12Deficiency Anemia 1. Pathophysiology 2. Clinical Manifestations 3. Assessment and Diagnostic Findings 4. Medical Management 5. Nursing Management