Report in
Biochemistry
(Diabetes Mellitus)
Stephanie Bernas
Contribution’ to the Reporting
“What enzymes that the diabetes
mellitus is lacking?”
Submitted To:
Mr. Francis Panaguiton
What enzymes that the diabetes
mellitus is lacking?
Glucose 6 Phosphate Dehydrogenase (G6pd)
Glucose-6-Phosphate Dehydrogenase is the first
step in the pentose phosphate pathway, which is
in charge of a series of chemical reactions that
convert glucose (a type of sugar found in most
carbohydrates) to ribose-5-phosphate.
G6pd are responsible for keeping red blood cells
healthy so they can function properly and live a
normal life span. This enzyme also protects red
blood
cells
from
damage
and
premature
destruction. This enzyme is involved in the
correct digestion of carbohydrates and is found
in almost all types of cells.
Diabetes is more likely to occur in patients
with poor glucose tolerance or fasting glucose.
A lack of this enzyme increases the
diabetes and impaired fasting glucose.
risk
of
Glucokinase
Glucokinase is a major regulator enzyme in the
pancreatic
beta-cell.
Also
known
as
the
pancreatic beta-cell sensor is an enzyme that
regulates insulin secretion.
When blood glucose levels rise, Glucokinase in
beta cells acts as a glucose sensor, boosting
insulin production.
It plays a vital role in the breakdown of sugars
in the body, found in the iver and beta cells in
the pancreas.