CHEMISTRYOFLIFE I.ELEMENTS–Asubstancethatcannotbebrokendownbynormalchemicalmeans. .Mosta bundantinlivingo rganisms: O xygen(65%),Carbon(18.5%),H ydrogen(9.5%),Nitrogen(3.2% ) A B.Atoms-Smallestp arto fa ne lementthath asa llo fitsc haracteristics 1 .Innucleus= a .Protons:+c harge;Thea tomicn umberspecifiesthep rotonn umber b.Neutrons: n eutralc harge;=Atomicm ass– Atomicn umber 2 .Electrons:n egativec harge:inEnergylevels: 1 st (2), 2 nd (8),3 rd (8) a .(Electron# =p roton# ifthereisn oc harge) b.Electron# =p roton# -c harge Example:Boron:Atomicm ass= 11;Atomic# = 5 ● Protonnumber= 5 (atomic# ); ● Neutron# = 6 (Atomicm ass– Atomic# ;11-5) ● Electron# = 5 (proton# -c harge;5 -0) ● Atomicdiagram:protonsa ndneutronsinnucleus ● Electronsin“ energylevels”: C.Isotopes:Havea d ifferent neutronn umberthanthem ost commonlyo ccurringa toms Carbon14has2 additionalneutrons thanCarbon12. D.Ion:Ac hargeda tom(differentn umbero fe lectrons); ELECTRON# =PROTONS– CHARGE;Nitrogen-3h as1 0e lectrons(=7--3) a .Cation:+c harge b .Anion:-c harge Nitrogen(-3) E.ChemicalBonds:Atomstrytofilluptheiro uter (valence)shello fe lectrons 1 .Ionicb onds: Atomstransfere lectronsa nd becomeo ppositelyc hargeda nda ttract Na🡪e -🡪Cl; -Nab ecomes+ ,Clb ecomes-🡪NaCl (tablesalt) 2 . Covalentb onds:Atomssharee lectrons;.Strongesta ndm ost commoninb ody Polar– Slightlyc hargedo ne ithersided uetou nevensharingo fe lectrons Hydrogenbonds: i.Betweenp olarm olecules Weakestb ond- Cohesion(b ondstoitself) -Adhesion(b ondstosomethinge lse 3. ii. - 4.Freer adicals– Reactivea tomswith unpairede lectrons -Antioxidants– Havee xtrae lectronsthatc an donatetofreeradicalstostabilizethem II.ChemicalReactions: Bondsa reb rokena ndreformed,Leadsto energystorageo rrelease -Activatione nergy:Energyn eededtob egin -Catalyst:Reducesa ctivatione nergy ANABOLIC BUILDINGm oleculesu singe nergy SYNTHESIS EXERGONIC(energye ntersthereaction) Dehydration(waterisp roducedinthep rocess) A+B+e nergy🡪AB+H2O Ex:ADP+P+e nergy🡪ATP+H2O CATABOLIC SPLITTINGMOLECULESRELEASINGENERGY DECOMPOSITION EXERGONIC(energye xitsthereaction) HYDROLYSIS(waterissplitd uringthereaction) AB+H2O🡪A+B+Energy Ex:ATP+H2O🡺ADP+P+e nergy III.AdenosineTriphosphate(ATP)–Suppliesenergytocells IV.AcidsandBases A.pHscale–-Measuresc oncentrationo fH +ionsina solution .7isn eutral;Acid=<7;Base=>7 1 2 .BLOODp H=7.35-7.45 B.LOGARITHMICSCALE 1.Achangein1numberonthescaleequatesto10X changeinstrength 2 .Example:4 is1 0Xm orea cidicthan5 ,1 00X(10^2) m orea cidicthan6 ,a nd1 000X(10^3)morea cidicthan7 V.OrganicCompounds: A.Containa Carbon“ skeleton”:“ BACKBONEO FLIFE” CARBONFORMSMULTIPLEc ovalentBONDS Organic Common Buildingblocks Main (monomer Compound Name function Carbohydrates Sugars Examples Monosaccharides Quickenergy ● ● Lipids Fats Fattyacids Proteins XXXX Aminoacids NucleicAcids Blueprint oflife Nucleotides Monosaccharides-Glucose Fructose,Galactose Disaccharide -Lactose,Sucrose, Maltose Polysaccharide-Glycogen Triglycerides–Storedenergy Phospholipids–Cellmembrane Waxes Hormones ● Energy ● reserves ● ● Protection ● ● Cell ● membrane ● Catalysts Enzymes Keratin ● Growth, Hemoglobin Myosin Actin maintenan Melanin ce,repair Heredity DNA(2strands) RNA (1strand) ● B.Enzymes:Proteinsthata cta sa c atalystina livingo rganism 1.DescribedbytheLocka ndK eyModel a .ENZYMESARESPECIFICTO1 MOLECULEAND ARERELEASEDUNCHANGED b .Enzymesc anb ed enaturedb yp Ha ndtemperature changes,orswitchedo ffb yg enes 2..Nameu suallye ndsin“ a se” (lactase,sucrose)