Transport System Transport System Lesson Objectives Understanding the importance of having transport system in some multicellular organisms Synthesizing the concept of circulatory system Why multicellular organism need the circulatory system? Cell needed nutrient and oxygen for metabolism reaction, while excretory product such as CO2 and urea need to be eliminated. Diffusion is one of main transport system that materials that will move passively between the external environment and the cell. So the cell can get what they need. This simple diffusion occurs only through the cell membrane. Why multicellular organism need the circulatory system? Let’s imagine for using cube in each organism. For exchange of substances, such as oxygen for these organisms occurs very quickly as they have a very large Why multicellular organism need the circulatory system? The surface area in contact with the outside environment is very large when compared to the volume of the inside of the organism. Its surface area to volume ratio (sa : vol) is large, so there is a relatively big surface area over which substances can diffuse into or out of the organism. The more bigger organism in size, the more lesser SA/V. Diffusion of substance becomes Questions What is the relationship between the size of cubes & the total surface area to volume (TSA/V) ratio? Which cube shows the largest value of TSA/V ratio? Explain your answer and relate the relationship of TSA/V with multicellular organism? How the multicellular organism can get nutrient and oxygen and deliver to each cell in their body? The basic strategy to overcome this problem is with a specific structure such as lungs and digestive system and let the substances reach each cell via circulatory system Circulatory System - Mass Transport System This efficiency of mass transport system enable human and animal cell to get their need sufficiently Blood & Its Components Six Main Functions 1. Transport materials from one place to another. 2. Provide a watery environment for individual cells. 3. Help maintain a constant internal temperature. 4. Combat disease and infection. 5. Help regulate the body’s pH level. 6. Prevent the loss of body fluids through clotting. Components of Blood 1. Plasma Fluid component Makes up 55% Other 45% is all cells 2. Red blood cells 3. White blood cells 4. Platelets Plasma Fluid component (90% water) Like a river carrying sediment Contains and transports: Proteins Red blood cells White blood cells Platelets Essential nutrients Enzymes Hormones Gases Organic salts Red Blood Cells – RBC (Erythrocytes) Makes up 43% of blood Transports oxygen and a little carbon dioxide on its hemoglobin Hemoglobin A protein Consists of a red pigment Contains iron Did you know? When oxygen is attached hemoglobin it appears RED. Each RBC contains 280 million hemoglobin molecules Once oxygen is released, the hemoglobin changes shape and reflects BLUE light. Can you see it under your skin? Red Blood Cells – RBC Produced in the bone marrow Contain a nucleus when produced, but it is lost in circulation Rate of 2.3 millions per second Gives a donut shape Used RBC are destroyed by the liver and spleen Red Blood Cell Facts 1 liter of blood can carry: 3 mL of oxygen without hemoglobin 200 mL of oxygen with hemoglobin Can survive 4.5 seconds Can survive 5 minutes Anemia is the lack of red blood cells or hemoglobin Causes: loss of blood or lack of dietary iron Red Blood Cell Facts Quantity is influenced by the sex, health, age, and altitude At high altitudes there is less oxygen so more RBC are created Men = 5.5 million RBC per mL of blood Women = 4.5 million RBC per mL of blood White Blood Cells (Leukocytes & Lymphocytes) Make up about 1% of blood Protect against illnesses and invaders Form the immune system Pus is created from dead white blood cells that have engulfed an invader Your own guard or doctor! White Blood Cells Larger than RBC Contain a nucleus Fact: There are 700 RBC for every white blood cell Platelets Make up about 1% of blood Necessary for coagulation (clotting) If broken blood vessel is found a set of chemical reactions is started Fibrin - a sticky network of protein fibers forms over the injury A dry and thick crust (scab) will form A natural band aid! Platelet Facts Hemophilia is a genetic blood disorder where clots cannot be formed Can die of blood loss Thrombosis is a clot that forms and closes off a blood vessel Clot in brain can cause an apoplectic stroke or a heart attack Clot that moves is an embolism and it very dangerous Complete Your Test Tube Identify 4 main components & their percentages Complete Review Table Any Questions? What kind of disease that will get after observe the blood test sample below? 1. Disease on the sample B, give me the reason why? What kind of disease that will get after observe the blood test sample below? 2. Disease on the sample A, give me the reason why? What kind of disease that will get after observe the blood test sample below? 3. Disease on the sample C, give me the reason why? 90% Concept Map Blood which is composed of Gases, cells, nutrients, etc. ____ % is made up of Cells function including which carry function a.k.a. coagulation __________ & __________ also known as erythrocytes types: leukocytes & lymphocytes