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Comparative study of 15% TCA peel versus 35% glycolic acid peel for the treatment of melasma - PubMed

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Indian Dermatol Online J. 2012 May;3(2):109-13. doi: 10.4103/2229-5178.96702.
Comparative study of 15% TCA peel versus 35%
glycolic acid peel for the treatment of melasma
Neerja Puri
1
Affiliations
PMID: 23130283 PMCID: PMC3481880 DOI: 10.4103/2229-5178.96702
Free PMC article
Abstract
Background: Chemical peels are the mainstay of a cosmetic practitioner's armamentarium because
they can be used to treat some skin disorders and can provide aesthetic benefit.
Objectives: To compare 15% TCA peel and 35% glycolic acid peel for the treatment of melasma.
Material and methods: We selected 30 participants of melasma aged between 20 and 50 years from
the dermatology outpatient department and treated equal numbers with 15% TCA and 35% glycolic
acid.
Results: Subjective response as graded by the patient showed good or very good response in 70%
participants in the glycolic acid group and 64% in the TCA group.
Conclusions: There was statistically insignificant difference in the efficacy between the two groups
for the treatment of melasma.
Keywords: Acne scarring; TCA; glycolic acid; melasma; peels; photoaging.
Figures
Figure 1a Melasma in a
Figure 1b After five
Figure 2a Melasma in a
22 year-old-girl…
sessions of 35%…
40-year-old lady…
Figure 2b After treatment
with 15% TCA…
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