CONCEPT: Glucose Regulation EXEMPLARS: Diabetes Mellitus Type 1 and Type 2 Instructions: Fill in the grid below to compare/contrast type 1 diabetes with type 2 diabetes. Diabetes Mellitus Type 1 The pancreas produces little or no insulin. Diabetes Mellitus Type 2 Body resists the effects of insulin or doesn’t produce enough insulin to maintain normal glucose levels What is different? Assessments – what signs and symptoms would you expect to see Increased thirst Frequent urination Bed-wetting in children Extreme hunger Unintended weight loss Fatigue and weakness Increased thirst Frequent urination Fatigue Weight loss Frequent sores Areas of darkened skin Type 2 has darkened areas of skin and more infections and slow healing sores. Type 1 has bed wetting because it is diagnosed in childhood Labs and Diagnostics – What tests would you expect, and specific values or results that are significant A1C ≥ 6.5%’ OR 8-hour fasting blood glucose level of > 126 mg/dl OR Oral glucose tolerance test of 200mg/dl or more in a 2-hour sample OR Random blood glucose level of 200mg/dl or more accompanied by classic signs of diabetes A1C test: 6.5% and higher on two separate tests Random blood sugars or 200 or higher In type 2 diabetes, the main indicator is the A1C test while in type 1 the blood sugar is the main test Medications – what medications would you expect to be prescribed for this disease process? Rapid-acting insulin Short-acting insulin Intermediate acting insulin Long-acting insulin Metformin Insulin Meglitinides Thiazolidinediones DPP-4 inhibitors Type 2 has oral medications, not just insulin unlike type 1 Brief Pathophysiology Type 2 is usually adult onset and type 1 is usually childhood onset Type 2 deals more with the body resisting insulin Acute Complications – What acute complications would you monitor for? Hypoglycemia Diabetic ketoacidosis Long Term Complications – What long term complications are you concerned about? Microvascular complications: eye, kidney and nerve disease (neuropathy) Heart disease Foot damage Monitor for hypoglycemia and diabetic ketoacidosis Patient Education – what educational needs would you anticipate with a new diagnosis? Hypoglycemia Hyperosmolar hyperglycemic nonketoic syndrome (high blood glucose) Neuropathy Kidney and eye damage Hearing impairment Sleep apnea High BP Eating low fat and calorie food. Exercise Type 2 diabetes has the HHS, not type 1 diabetes Sleep apnea because of obesity in type 2 not in type 1 type 2 has losing weight because obesity contributes to type 2 Diabetes Medication Review Questions 1. Which is the most appropriate timing regarding the nurse's administration of a rapid-acting insulin to a hospitalized patient? a. Give it 15 minutes before the patient begins a meal. b. Give it ½ hour before a meal. c. Give it 1 hour after a meal. d. The timing of the insulin injection does not matter with insulin lispro. 2. Which statement is appropriate for the nurse to include in patient teaching regarding type 2 diabetes? a. “Insulin injections are never used with type 2 diabetes.” b. “You don't need to measure your blood glucose levels because you are not taking insulin injections.” c. “A person with type 2 diabetes still has functioning beta cells in his or her pancreas.” d. “Patients with type 2 diabetes usually have better control over their diabetes than those with type 1 diabetes.” 3. The nurse monitoring a patient for a therapeutic response to oral antidiabetic drugs will look for: a. fewer episodes of diabetic ketoacidosis (DKA). b. weight loss of 5 pounds. c. hemoglobin A1C levels of less than 7%. d. glucose levels of 150 mg/dL. 4. A patient with type 2 diabetes is scheduled for magnetic resonance imaging (MRI) with contrast dye. The nurse reviews the orders and notices that the patient is receiving metformin (Glucophage). Which action by the nurse is appropriate? a. Proceed with the MRI as scheduled. b. Notify the radiology department that the patient is receiving metformin. c. Expect to hold the metformin the day of the test and for 48 hours after the test is performed. d. Call the prescriber regarding holding the metformin for 2 days before the MRI is performed. 5. A patient with type 2 diabetes has a new prescription for repaglinide (Prandin). After 1 week, she calls the office to ask what to do, because she keeps missing meals. “I work right through lunch sometimes, and I'm not sure whether I need to take it. What do I need to do?” What is the nurse's best response? a. “You need to try not to skip meals, but if that happens, you will need to skip that dose of Prandin.” b. “We will probably need to change your prescription to insulin injections because you can't eat meals on a regular basis.” c. “Go ahead and take the pill when you first remember that you missed it.” d. “Take both pills with the next meal, and try to eat a little extra to make up for what you missed at lunchtime.” 6. Which action will the nurse recommend to a client with type 1 diabetes on insulin therapy who has been having a morning fasting blood glucose (FBG) level of 160 mg/dL and is diagnosed with “Somogyi phenomenon” to achieve better control? a. “Avoid eating any carbohydrate with your evening meal.” b. “Eat a bedtime snack containing equal amounts of protein and carbohydrates.” c. “Inject the insulin into your arm rather than in the abdomen right around the navel.” d. “Take your evening insulin dose right before going to bed instead of at supper time.”