Mammalian Digestive System 2.2.5: Trace the digestion of foods in a mammalian digestive system, including: – physical digestion – chemical digestion – absorption of nutrients, minerals and water – elimination of solid waste The table shows the main structures and associated organs of the human digestive system (alimentary canal) and their functions. The diagram shows the main structures of the digestive system. 1 The Process of Digestion Digestion is the breaking down of large and complex food particles into much smaller and simpler particles. There are two types of digestion: physical (mechanical) and chemical. The overall aim of digestion is to break down the particles into substances that are small enough to be absorbed through the intestinal walls into the bloodstream. Physical Digestion This involves the physical breakdown of food particles. It begins in the mouth when the different types of teeth break food into smaller pieces by cutting, tearing, chewing and grinding the food. The churning motion of the stomach continues the process of physical digestion. The aim of this physical digestion id to start the process of breaking food into smaller pieces so that its surface area is increased and it can then be acted on by enzymes in chemical digestion. Chemical Digestion Chemical digestion is the process of using digestive enzymes to chemically break down the large, complex molecules in the food that has been ingested into their smaller, simpler forms. Some of the simple substances obtained are glucose from complex carbohydrates, amino acids from proteins, glycerol and fatty acids from lipids and nucleotides from nucleic acids. Pathway Through Digestive System 1. Mouth After food enters the mouth, physical digestion begins the process of the breakdown of the food. Teeth break the food up into smaller pieces with greater surface area for the more efficient action of enzymes. Salivary amylase is released into the mouth, and is mixed with the food by the tongue and the action of chewing. This enzyme begins the chemical breakdown of the complex carbohydrate starch into the simpler sugar maltose. Once the food has been chewed into small pieces and mixed with saliva, the tongue forms it into a ball shape called the bolus. This is then swallowed and enters the oesophagus. 2. Oesophagus Once the bolus enters the oesophagus, it travels along the soft-walled, muscleringed tube to the stomach. As it passes the entrance to the trachea, a flap of skin, the epiglottis, closes over this entrance to prevent the entry of food into the respiratory system. The bolus of food does not move down the oesophagus just due to gravity. Muscular contractions also move the bolus by a process called peristalsis. 2 3. Stomach diaphragm At the entry and exit of the stomach, are narrow openings whose opening and closing are controlled by circular sphincter muscles. This controls the movement of substances into and out of the stomach. Once inside the stomach, relaxation and contraction of the stomach walls continue physical digestion. The bolus breaks up into pieces that combine with gastric juices contained within the stomach to form a mixture of known as chyme. Gastric juices, secreted from the wall of the stomach, contain water, hydrochloric acid, pepsinogen and pepsin. The acid causes the pH of the interior of the stomach to be at 2.0 – 3.0. Mucus lining the stomach prevents the acid from ‘eating away’ the walls of the stomach. oesophagus Cardiac sphincter Pyloric sphincter Stomach lining Diagram showing the structure of the stomach The enzyme pepsinogen is converted into an active form called pepsin in the acidic environment and begins the chemical breakdown of the long chained proteins into shorter chained peptides. Pepsin also breaks down nucleic acids (DNA and RNA) in the food to their component nucleotides. The chyme remains in the stomach for about 6 hours. 4. Small intestine The chyme from the stomach enters the small intestine gradually through a small muscular opening, the pyloric sphincter. The highly folded small intestine is approximately 7m long in an adult and contains 3 main regions: the duodenum (at the start of the small intestine), the jejunum (middle section) and the ileum (end region). Diagram showing 3 parts of small intestine As the chyme enters the duodenum, it stimulates the release of a hormone, which in turn stimulates the release of pancreatic juices into the area. Pancreatic juices are secreted by the pancreas and contain a mixture of the digestive enzymes amylase, trypsin and lipase as well as bicarbonate ions. The 3 bicarbonate ions act to neutralise the acidic chyme leaving the stomach. Amylase and trypsin continue the chemical breakdown of carbohydrates and proteins. When there are lipids present in the chyme, bile is released into the duodenum. Bile is produced by the liver and is stored in the gall bladder. Bile is not a digestive enzyme. It acts in the same way as detergent acts on fats when washing a greasy saucepan- it breaks down (emulsifies) the fats into smaller pieces or fat droplets. This increases the surface are for the action of the digestive enzyme lipase to chemically break the lipids into fatty acid and glycerol molecules. From the duodenum, food enters the jejunum where most of the absorption of the digestive products occurs. Absorption in the digestive tract The absorption of substances mostly occurs in the jejunum section of the small intestine. Some substances, such as alcohol and drugs, are absorbed quickly into the stomach. The products of digestion including amino acids, glucose, fatty acids and glycerol, move into the transport systems of the body in the small intestine. These products are moved by diffusion or active transport through tiny projections called villi, which line the intestinal wall. These projections greatly increase the surface area for much more efficient diffusion. Villi walls are moist and are one cell thick. They have a rich blood supply in the tiny capillaries that are wrapped around a lacteal. Lacteals are connected to another transport system in the body- the lymph Diagram of villi in small intestine system. Glucose and amino acids are absorbed into the capillaries, while fatty acids and glycerol move into the lacteal. Some water absorption will also occur here. 5. Liver Digested food, once absorbed into the bloodstream, travels to the liver, which is the centre of food metabolism. It plays an important role in keeping sugars, glycogen, and protein levels in balance in the body. It also detoxifies blood. 4 6. Large Intestine When all the required digestive products have been absorbed in the small intestine, the remaining undigested material moves to the large intestine. This material is composed of substances such as water, salts and dietary fibre. The large intestine has two main sections: the colon and the rectum. In the colon, the water and Diagram showing the parts of the large intestine some salts are absorbed back into the bloodstream, with the undigested material compacting into a more solid substance. Vitamins A and K, which are produced by bacteria in the colon acting on the undigested matter, are also absorbed into the bloodstream. Elimination of Solid Waste The remaining waste material, known as faeces, is moved into the rectum by peristalsis and then egested, or eliminated, from the body through the anus. The end products of digestion can be built up by the body into useful substances, as either new biological material or an energy source. For example, in mammals such as humans, blood transports the products of digestion to where they are needed in the body. They can then be reassembled by the cells of the body into structural parts (for example, lipids and proteins form structural part of cell membranes, and protein fibres in muscle tissue) or into energy storage (for example, fatty tissue or fat beneath the skin, or the carbohydrate glycogen, a form of ‘animal starch’ in the liver and muscles). Protein cannot be stored. 5 Questions Using the information in this booklet, answer the following questions: 1. Define the term digestion. 2. Outline the main functions of the digestive system. 3. Distinguish between physical and chemical digestion and identify where in the digestive system each of these occurs. Use a table with suitable headings to answer this question. 4. Identify and draw a flow chart to show, the structures that food must pass through in a typical mammalian digestive system. 6 5. Complete the table below. Table of nutrients and the simple digestive products they form Nutrient Digestive Products formed proteins nucleic acids carbohydrates lipids 6. Outline the function of bile and identify where it is stored and where it is produced. 7. Outline the function of the following enzymes: a. Amylase b. Pepsin c. Trypsin d. Lipase 7 8. Identify the structures that increase the surface area of the internal wall of the small intestine and explain how these structures assist the absorption of the products of digestion. 9. Determine whether the material egested from the digestive system is part of the internal or external environment. Justify your answer. 8 10. Construct a summary table identifying each organ of the digestive system and its function. 9