CHAPTER 12 GENETICS March 8 and 10: Introduction to Genetics/ Further exploring gene expression At Home learners: Take the Check-In survey ALL STUDENTS: Write a hypothesis to the question posed in the schoology discussion: “How Did Noelle Get These Parakeets?” i Write a hypothesis for the chapter mystery problem. Write a hypothesis for the chapter mystery problem. March 10, 2021 If you’re remote: Fill in the check in form ALL STUDENTS: Fill in the Dominant and Recessive Trait survey in the week 9 folder in schoology. Remote Learners ● ● ● ● Finish your assessment from last week Complete the Note Taking Guide for 12.1 Work in breakout rooms if you choose. Leave when you’re finished. March 16, 2021 THE WORK OF GREGOR MENDEL ● CHECK IN IS DIFFERENT! I’m just going to be checking in with you as you arrive. ● Make sure you’ve got a coin with you :) ● Open the 12.1 note taking guide you completed last week (it should be in your google docs) ● Open the “Probability and Heredity” Note taking guide in Notability. MODEL SYSTEMS • Mendel used pea plants as a model system to study genetics. • Discuss and write some reasons why peas were better than using other common agricultural organisms. THE ROLE OF FERTILIZATION • How are pea plants typically fertilized? • How did Mendel modify how they were fertilized? GENES AND ALLELES • Traits are controlled by genes • Genes often have two or more alleles • Which traits did Mendel study? What were the alleles for those traits? Trait Alleles Dominant trait Recessive trait Seed shape Round and Wrinkled Round Wrinkled DOMINANT AND RECESSIVE ALLELES An organism with a recessive allele will only express that trait if the dominant allele is not present. • Of the traits that Mendel studied which alleles were dominant and which were recessive? Trait Alleles Dominant trait Recessive trait Seed shape Round and Wrinkled Round Wrinkled Seed Color Yellow and Green Seed Coat Gray and White Pod Shape Smooth and constricted Pod Color Green and yellow Flower Position Axial and terminal Plant Height Tall and short Trait Alleles Dominant trait Recessive trait Seed shape Round and Wrinkled Round Wrinkled Seed Color Yellow and Green Yellow Green Seed Coat Gray and White Gray White Pod Shape Smooth and constricted Smooth Constricted Pod Color Green and yellow Green Yellow Flower Position Axial and terminal Axial Terminal Plant Height Tall and short Tall Short DOMINANT AND RECESSIVE TRAITS IN HUMANS • Look at the class data. Can you infer which traits are dominant and which are recessive? DOMINANT AND RECESSIVE TRAITS • KEY IDEA: Dominant does not mean “common”. • Some forms of Polydactyly (having multiple fingers or toes) is actually a dominant trait, although rare in the population. • Why do you think some recessive traits are more common in the population? SEGREGATION • Describe each generation below. • P generation: • F1 generation: • F2 generation: • What did Mendel conclude from this? • FORMATION OF GAMETES • Alleles separate during gamete formation. (Gametes are reproductive cells: egg and sperm) • Offspring receive one allele from each parent CHAPTER 11 LESSON 2 PROBABILITY AND HEREDITY March 18, 2021 Probability and Heredity Warm up: ● How many times should your coin be heads if you flip it 10 times? Type your answer in the chat! ● Attendance: Scale of chihuahuas, how are you? WHAT ARE THE ODDS? • What is the probability that your coin will land heads up? • Test your hypothesis by flipping your coin 10 times. • • Track your progress using the “FIRST: Single Coin Flip Class Data Collection Form” After 10 Flips summarize your data with form “SECOND: Single Coin Flip Data Summary” WHAT ARE THE ODDS? • Write a hypothesis. What is the probability that you AND your partner will flip: • both heads? • heads and a tails? • both tails? • At home: Use the chat. • In person: Share out loud (I’ll put it on the board) WHAT ARE THE ODDS? • What is the probability that you AND your partner will flip: • heads? • heads and a tails? • two tails? • Test your hypothesis: Use the “THIRD: 2 coin flips data collection” form WHAT ARE THE ODDS? • Flip two coins with a partner (a total of 4 coins flipped) • What is the probability you and your partner will get • heads on one penny, tails on the other and two heads on your silver coins? Write a hypothesis: At home use the chat, in person I’ll call on you. CHAPTER 11 LESSON 2 PROBABILITY AND HEREDITY STUDENTS WILL BE ABLE TO • Appropriately choose symbols to represent alleles when completing Punnett squares. • Use Punnett squares to predict possible phenotypes and genotypes single and dual trait crosses. TERMS WE WILL USE: • Define and provide an example of the following • Homozygous: • Heterozygous: • Genotype: • Phenotype: CHOOSING SYMBOLS • Same letter is used for both alleles • Named after dominant allele • Dominant allele is capitalized, and recessive is lowercase. • Choose appropriate symbols to represent the alleles for the traits that Mendel studied. Trait Alleles Dominant Recessive trait symbol trait symbol Seed shape Round and Wrinkled R Seed Color Yellow and Green Seed Coat Gray and White Pod Shape Smooth and constricted Pod Color Green and yellow Flower Position Axial and terminal Plant Height Tall and short r WHAT IS THE PHENOTYPE OF EACH OF THE FOLLOWING PEA PLANTS FROM MENDEL’S TESTS? Include if the trait is homozygous or heterozygous • Rr: • tt: • GG: • Yy: • AA: • aa: PUNNETT SQUARES B b B BB Bb b Bb bb • Alleles from parent 1 • Alleles from parent 2 • Possible genotypes of offspring PUNNETT SQUARE PRACTICE Show a cross between two heterozygous yellow seed pea plants • PUNNETT SQUARE PRACTICE Show a cross between two heterozygous green pod pea plants PUNNETT SQUARE PRACTICE • Show a cross between a short pea plant and a heterozygous tall pea plant. PUNNETT SQUARE PRACTICE • Show a cross between a short pea plant and a homozygous tall pea plant. INDEPENDENT ASSORTMENT • Mendel: “Does segregation of one pair of alleles affect another set of alleles?” • Punnett square predictions • F1: • F2: • Observations: • Conclusions: March 22, 2021 Probability and Heredity Warm up: ● Take out your punnett square practice worksheet. ● Correct it in a different color. (answer key in schoology) ● Attendance: Scale of Patrick, how are you? WARM UP • Take out two different coins: a penny and one other • If both you and a partner each flip a penny and a silver coin, what is the probability that you will flip two heads on your penny and two tails on your silver coin (nickel/dime/quarter, etc.)? • Test this hypothesis. A google form has been sent to you to help. TWO FACTOR CROSS ● ● Traits often work in conjunction with each other. Mendel studied seed appearance (round/wrinkled and yellow/green) TWO FACTOR CROSS ● ● ● To determine the probability of getting a combination of traits, we need to use a more complex punnett square This shows a self pollinating heterozygous wrinkled; heterozygous yellow seed plant. This “Dihybrid cross” results in a 9:3:3:1 ratio of phenotypes. 9/16: Round Yellow 3/16: Round Green 3/16: Wrinkled Yellow 1/16: Wrinkled Green TWO FACTOR CROSS INSTRUCTIONS • Determine all combinations of alleles that each parent can pass along • Use FOIL method to help with this • Check: You should have two letters above each box. Each should represent a different trait. • Copy alleles into boxes. • Check: All boxes should have 4 letters in them, two of each. • Keep the same letters together and write capital letters first. • Use highlighters, markers, or symbols to mark the phenotypes in each box. • Dihybrid crosses result in a 9:3:3:1 ratio TWO FACTOR CROSS PRACTICE • What is the probability of each genotype and phenotype in a cross between a homozygous round, green seeded plant and a heterozygous round, heterozygous yellow seeded plant? • What is the probability of each genotype and phenotype in a cross between a heterozygous round, heterozygous yellow seeded plant and a wrinkled, green seeded plant? • What is the probability of each genotype and phenotype in a cross between a homozygous round, green seeded plant and a heterozygous round, heterozygous yellow seeded plant? Ry Ry Ry Ry RY RRYy RRYy RRYy RRYy Ry RRyy RRyy RRyy RRyy rY RrYy RrYy RrYy RrYy ry Rryy Rryy Rryy Rryy 50% round yellow seeds, 50% round green seeds • What is the probability of each genotype and phenotype in a cross between a heterozygous round, heterozygous yellow seeded plant and a wrinkled, green seeded plant? RY Ry rY ry ry RrYy Rryy rrYy rryy ry RrYy Rryy rrYy rryy ry RrYy Rryy rrYy rryy ry RrYy Rryy rrYy rryy 25% round yellow seeds, 25% round green seeds, 25% wrinkled yellow seeds, 25% wrinkled green seeds March 25, 2021 OTHER PATTERNS OF INHERITANCE (non Mendelian Genetics) ● Open up the Non Mendelian Genetics note taker in notability ● INCOMPLETE DOMINANCE • Alleles are neither dominant or recessive; heterozygous individuals don’t fully express either trait • Examples: • • Four o’clock flowers andalusian chickens • What symbols would you suggest to communicate this? INCOMPLETE DOMINANCE • Predict the probability of each genotype and phenotype if you cross a pink four o'clock flowered with another pink four o'clock flower plant INCOMPLETE DOMINANCE • Predict the probability of each genotype and phenotype if you cross a white four o'clock plant with a pink four o'clock flowered plant CODOMINANCE Both traits are fully expressed. Examples: ● ● ● Erminette chickens Camelias Blood type (A and B are codominant and produce type AB) CODOMINANCE: Symbols Capital letters named after trait Superscript for alleles. Chicken feather Camellia petal color color Blood type CODOMINANCE • What is the probability that an erminette chicken crossed with another erminette chicken will produce a black chicken? • A white chicken? • Another erminette chicken? MULTIPLE ALLELES • There’s more than two possibilities for types of alleles • Examples: • Rabbit fur coat color. • Blood type in humans (antibodies on surface called “Immunoglobulin” CODOMINANCE and MULTIPLE ALLELES • If a parent who is heterozygous type A blood has children with someone who is heterozygous type B, what blood types could the children have? CODOMINANCE and MULTIPLE ALLELES • If a parent who is homozygous type A blood has children with someone who is homozygous type B, what blood types could the children have? CODOMINANCE and MULTIPLE ALLELES • If a parent who is type AB blood has children with someone who is type O blood, what blood types could the children have? POLYGENIC TRAITS • Many traits are produced by the interaction of many genes. This often leads to a range or spectrum of phenotypes. • Examples: ● ● ● Eye color of fruit flies Skin color of humans Feather color in parakeets GENES AND THE ENVIRONMENT • An environmental conditions affect gene expression and phenotype • Examples: • • Western white butterflies Siamese cats Revisit your hypothesis. After talking to the pet shop owner, Noelle learned that two genes control feather color. A dominant Y allele results in the production of a yellow pigment. The dominant B allele controls melanin production. If the genotype contains at least one Y and one B allele, the offspring will be green. If the genotype contains two recessive y alleles and at least one dominant B allele, the offspring will be blue. If the offspring contains two recessive y alleles and two recessive b alleles, the offspring will be white. ● What are the genotypes of each of the 5 birds that Noelle now has? Discuss with your pod.