Chapter 1 Introduction and descriptive epidemiology : history and uses of epidemiology Learning Objectives: At the end of this unit the student is expected to: • describe the key aspects of epidemiology • Discuss the uses of Epidemiology • Identify the basic study designs used in epidemiology • recognize the role of epidemiology in society and link epidemiology to nursing practice. . History of Epidemiology • John Snow. • In 1849, John Snow, an English physician, formulated and tested a hypothesis concerning the origin of an epidemic of cholera in London.. John Snow’s Map http://scienceblogs.com/significantfigures/ind ex.php/2013/03/11/200-years-of-dr-johnsnow-a-significant-figure-in-the-world-ofwater/ History of Epidemiology • Between 1849 and 1854, the Lambeth Company changed its source to an area of the Thames where the water was "quite free from the sewage of London." The rates of cholera declined in those areas of the city supplied by the Lambeth Company, while there was no change in those areas receiving water from the Southwark and Vauxhall Company. • Finally, Snow concluded that the source of cholera outbreak was contaminated water. What is epidemiology • Epidemiology is the study of how disease is distributed in populations and the factors that influence or determine this distribution. • Epidemiology is about the understanding of disease development and the methods used to uncover the etiology, progression, and treatment of the disease. • It is the study of patterns of disease, risk behaviors and protective factors in human populations. Definition • Epidemiology as defined by Last is “the study of the distribution and determinants of health-related states or events in specified populations, and the application of this study to the prevention and control of health problems” Definition of epidemiology Study • includes: surveillance, observation, hypothesis testing, analytic research and experiments. Distribution • refers to analysis of: times, persons, places and classes of people affected. Determinants • include factors that influence health: biological, chemical, physical, social, cultural, economic, genetic and behavioral. Healthrelated states and events • refer to: diseases, causes of death, behaviors such as use of tobacco, positive health states, reactions to preventive regimes and provision and use of health services. Specified populations • include those with identifiable characteristics, such as occupational groups. Application to prevention and control • the aims of public health—to promote, protect, and restore health. THINK-PAIR-SHARE ACTIVITY If you were a nurse in Snow’s time, list what hypotheses you might generate about cholera transmission from these observations. Uses of Epidemiology • To make a community diagnosis. Epidemiology helps to identify and describe health problems in a community (for example, the prevalence of anemia, or the nutrition status of children). • To monitor continuously over a period of time the change of health in a community. (for example, the effect of a vaccination program, health education, nutritional supplementation). Uses of Epidemiology • To practice surveillance for a specific disease in order to be able to act quickly and so cut short any outbreak (example cholera) • To investigate an outbreak of a communicable disease, analyze the reasons for it, plan a feasible remedy and carry it out, and monitor the effects of the remedy on the outbreak. • To plan effective health services. Effective services, interventions and remedies all depend on accurate community data. Objectives of Epidemiology 1. Identify disease etiology 2. Determine the burden of disease 3. Study the natural history of disease 4. Evaluate preventive and therapeutic measures 5. Provide foundation for public policy Descriptive vs. Analytical Epidemiology Descriptive Epidemiology Includes activities related to characterizing the distribution of diseases within a population Analytical Epidemiology Concerns activities related to identifying possible causes for the occurrence of diseases Disease distribution also known as: (Descriptive epidemiology) • Disease distribution is considered in terms of Persons, time and place (Who, when and where). Person Place Time Persons • Persons who are affected by disease in terms of age, sex, race, occupation etc. • The common characteristics relating to those persons affected by disease. Time • Time relates to when the diseases is most likely to increase e.g. an epidemic, endemic, seasonal, cyclic etc . Place • Place refer to the geographical distribution of a diseases and the common characteristics that are favorable for that diseases in the given locality. • Some diseases are localized, regional, pandemic etc Disease determinant factors • also knows as “Analytic epidemiology” • it include the Agent, host and environment Epidemiology and prevention Epidemiology and clinical practice • Epidemiology is critical not only to public health but also to clinical practice. The practice of medicine is dependent on population data. • Example, if a physician hears an apical systolic murmur, how does he or she know that it represents mitral regurgitation? Where did this knowledge originate? The diagnosis is based on correlation of the clinical findings (such as the auscultatory findings—sounds heard using a stethoscope) with the findings of surgical pathology or autopsy and with the results of catheterization or angiography studies in a large group of patients. Link epidemiology to nursing practice Epidemiological studies can potentially offer considerable benefits to the way nurses incorporate health-related practices into their professional role. Epidemiological studies also offers a valuable opportunity for the nursing profession to become more active in helping to determine health policy issues. • How does epidemiology relate to nursing? • Why is epidemiology important in the nursing profession? • Can nurses be epidemiologists? Summary • Epidemiology is the study of the distribution and determinants of health-related states in populations • Epidemiology is an invaluable tool for providing a rational basis on which effective prevention programs can be planned and implemented. REFERENCES Celentano, D., Szklo, M. and Gordis, L. (2019). Gordis epidemiology Section I : Page from 2 to 19