Electronogram 1 - Hydropic dystrophy of parenchymal
cells (Balloon Dystrophy)
1. Part of parenchyma cells
2. Changes in nuclei - Only part because of ultra picture . It is normal
and unchanged.
3. Changes in cytoplasm - Accumulation of protein fluid due to
expansion of sarcoplasmic reticulum - SR is expanded forming large
vacuoles (very large) filled by protein fluid.
4. Changes in organelles - Mitochondrion are enlarged , abnormal ,
abnormal partly destroyed. Ribosome are decreased in size and
number , compressed by vacuoles
5. Hydropic dystrophy of parenchymal cells (Balloon Dystrophy)
Electronogram 2 - Fibrinoid degeneration of collagen
fibres
1. Collagen fibres
2. - 4. Collagen fibres are swelled , partly destroyed due to deposition
between them of masses of pathological protein - fibrinoid (Black)
5. Fibrinoid degeneration of collagen fibres
Electronogram 3 - Amyloidosis of glomeruli
1. Part of glomerular filter
2. - 4. Deposits between endothelium and basement membrane of
glomeruli are seen of amyloid. Depositions of pathological protein
substance is observed between endothelium and basement membrane
of bowman's capsule. Deposition is irregular.
5. Amyloidosis of glomeruli
Electronogram 4 - Ischemia of myocardium ( Necrobiosis
or pre necrotic stage )
1. Part of myocardiocyte
2. Nuclei is not represented
3. Endoplasmic reticulum is expanded forming vacuoles filled by
protein fluid ( Balloon / Hydropic Dystrophy ) . Also can be seen
large lipid inclusions.
4. Mitochondrion are enlarged , abnormal , some of them partially
destroyed , myofibrils are swelled beginning to rupture in disk.
5. Ischemia of myocardium ( Necrobiosis or pre necrotic stage )
Electronogram 5 - Emigration of leukocytes through the
vessel wall in stage of exudation , inflammation .
1. Part of blood vessel
2. - 4.
• Part A - Vessel wall , Segmented nuclear leukocytes are stick to the
vessel wall inside lumen (margination of leukocytes)
• Part B- Leukocytes are inside the wall between endothelium and
basal membrane of blood vessel. This is called leukodiapedesis
5. Emigration of leukocytes through the vessel wall in stage of
exudation , inflammation .
Electronogram 6 - Hypertrophy of heart myocardium
stage compensatory
1. Cardiomyocytes with mitochondrion and myofilaments
2. - 4. Mitochondrion are increased in number and size.
5. Hypertrophy of heart myocardium stage compensatory
Electronogram 7 - Hypertrophy of heart myocardium
stage decompensatory
1. Cardiomyocytes with mitochondrion , myofilaments and lipids
2. - 4. Mitochondrion changes include swelling , refraction and
destruction of cristae . Structure of myocardium locally destroyed .
Small lipid droplet seen near mitochondrion.
5. Hypertrophy of heart myocardium stage decompensatory
Electronogram 8 - Cellular atypia
1. Cell
2. Nucleus is enlarged significantly , irregular, with 2 nucleases
(polyploidy) , chromatin is placed on periphery , irregularly spreading.
3. Less amount of cytoplasm . Ratio nuclear : cytoplasm is 1:1 .
Normally ratio is 1:6 or 1:4 . Nucleus cannot be more than 25% of
cell.
4. Set of organelles is different in amount , content & size.
5. Cellular atypia (Ultrastructural atypia of tumor cell )
Electronogram 9 - Subacute / Membranous / Immune
complexes glomerulus nephriti
1. Part of glomerular filter
2. - 4. Deposition of immune complex is seen on basal membrane of
Bowman’s capsule . They are divided by processes . Basal membrane is
rough . Podocytes have lost their pedicles (outgrowths).
5. Subacute / Membranous / Immune complexes glomerulus nephritis
Electronogram 10 - Cropous pneumonia resolution stage
( 3-4 stage )
1. Alveolar space ( space inside alveoli )
2. - 4. Segmentary nucleo leukocytes which are in contact with fibrinose
exudate poor by lysosomes (use them for resolution ) . Leukocytes far
from exudates are rich by lysosomes .
3. Cropous pneumonia resolution stage ( 3-4 stage )